MedMimic: Physician-Inspired Multimodal Fusion for Early Diagnosis of Fever of Unknown Origin

Fever of unknown origin FUO remains a diagnostic challenge. MedMimic is introduced as a multimodal framework inspired by real-world diagnostic processes. It uses pretrained models such as DINOv2, Vision Transformer, and ResNet-18 to convert high-dimensional 18F-FDG PET/CT imaging into low-dimensional, semantically meaningful features. A learnable self-attention-based fusion network then integrates these imaging features with clinical data for classification. Using 416 FUO patient cases from Sichuan University West China Hospital from 2017 to 2023, the multimodal fusion classification network MFCN achieved macro-AUROC scores ranging from 0.8654 to 0.9291 across seven tasks, outperforming conventional machine learning and single-modality deep learning methods. Ablation studies and five-fold cross-validation further validated its effectiveness. By combining the strengths of pretrained large models and deep learning, MedMimic offers a promising solution for disease classification.

TencentPretrain: A Scalable and Flexible Toolkit for Pre-training Models of Different Modalities

Recently, the success of pre-training in text domain has been fully extended to vision, audio, and cross-modal scenarios. The proposed pre-training models of different modalities are showing a rising trend of homogeneity in their model structures, which brings the opportunity to implement different pre-training models within a uniform framework. In this paper, we present TencentPretrain, a toolkit supporting pre-training models of different modalities. The core feature of TencentPretrain is the modular design. The toolkit uniformly divides pre-training models into 5 components: embedding, encoder, target embedding, decoder, and target. As almost all of common modules are provided in each component, users can choose the desired modules from different components to build a complete pre-training model. The modular design enables users to efficiently reproduce existing pre-training models or build brand-new one. We test the toolkit on text, vision, and audio benchmarks and show that it can match the performance of the original implementations.

A Simple and Effective Method to Improve Zero-Shot Cross-Lingual Transfer Learning

Existing zero-shot cross-lingual transfer methods rely on parallel corpora or bilingual dictionaries, which are expensive and impractical for low-resource languages. To disengage from these dependencies, researchers have explored training multilingual models on English-only resources and transferring them to low-resource languages. However, its effect is limited by the gap between embedding clusters of different languages. To address this issue, we propose Embedding-Push, Attention-Pull, and Robust targets to transfer English embeddings to virtual multilingual embeddings without semantic loss, thereby improving cross-lingual transferability. Experimental results on mBERT and XLM-R demonstrate that our method significantly outperforms previous works on the zero-shot cross-lingual text classification task and can obtain a better multilingual alignment.

SAMP: A Toolkit for Model Inference with Self-Adaptive Mixed-Precision

The latest industrial inference engines, such as FasterTransformer1 and TurboTransformers, have verified that half-precision floating point (FP16) and 8-bit integer (INT8) quantization can greatly improve model inference speed. However, the existing FP16 or INT8 quantization methods are too complicated, and improper usage will lead to performance damage greatly. In this paper, we develop a toolkit for users to easily quantize their models for inference, in which a Self-Adaptive Mixed-Precision (SAMP) is proposed to automatically control quantization rate by a mixed-precision architecture to balance efficiency and performance. Experimental results show that our SAMP toolkit has a higher speedup than PyTorch and FasterTransformer while ensuring the required performance. In addition, SAMP is based on a modular design, decoupling the tokenizer, embedding, encoder and target layers, which allows users to handle various downstream tasks and can be seamlessly integrated into PyTorch.