Semantic Lens: Instance-Centric Semantic Alignment for Video Super-Resolution

As a critical clue of video super-resolution (VSR), inter-frame alignment significantly impacts overall performance. However, accurate pixel-level alignment is a challenging task due to the intricate motion interweaving in the video. In response to this issue, we introduce a novel paradigm for VSR named Semantic Lens, predicated on semantic priors drawn from degraded videos. Specifically, video is modeled as instances, events, and scenes via a Semantic Extractor. Those semantics assist the Pixel Enhancer in understanding the recovered contents and generating more realistic visual results. The distilled global semantics embody the scene information of each frame, while the instance-specific semantics assemble the spatial-temporal contexts related to each instance. Furthermore, we devise a Semantics-Powered Attention Cross-Embedding (SPACE) block to bridge the pixel-level features with semantic knowledge, composed of a Global Perspective Shifter (GPS) and an Instance-Specific Semantic Embedding Encoder (ISEE). Concretely, the GPS module generates pairs of affine transformation parameters for pixel-level feature modulation conditioned on global semantics. After that, the ISEE module harnesses the attention mechanism to align the adjacent frames in the instance-centric semantic space. In addition, we incorporate a simple yet effective pre-alignment module to alleviate the difficulty of model training. Extensive experiments demonstrate the superiority of our model over existing state-of-the-art VSR methods.

Approximation of nearly-periodic symplectic maps via structure-preserving neural networks

A continuous-time dynamical system with parameter $\varepsilon$ is nearly-periodic if all its trajectories are periodic with nowhere-vanishing angular frequency as $\varepsilon$ approaches 0. Nearly-periodic maps are discrete-time analogues of nearly-periodic systems, defined as parameter-dependent diffeomorphisms that limit to rotations along a circle action, and they admit formal $U(1)$ symmetries to all orders when the limiting rotation is non-resonant. For Hamiltonian nearly-periodic maps on exact presymplectic manifolds, the formal $U(1)$ symmetry gives rise to a discrete-time adiabatic invariant. In this paper, we construct a novel structure-preserving neural network to approximate nearly-periodic symplectic maps. This neural network architecture, which we call symplectic gyroceptron, ensures that the resulting surrogate map is nearly-periodic and symplectic, and that it gives rise to a discrete-time adiabatic invariant and a long-time stability. This new structure-preserving neural network provides a promising architecture for surrogate modeling of non-dissipative dynamical systems that automatically steps over short timescales without introducing spurious instabilities.

Image Translation Based Nuclei Segmentation for Immunohistochemistry Images

Numerous deep learning based methods have been developed for nuclei segmentation for H&E images and have achieved close to human performance. However, direct application of such methods to another modality of images, such as Immunohistochemistry (IHC) images, may not achieve satisfactory performance. Thus, we developed a Generative Adversarial Network (GAN) based approach to translate an IHC image to an H&E image while preserving nuclei location and morphology and then apply pre-trained nuclei segmentation models to the virtual H&E image. We demonstrated that the proposed methods work better than several baseline methods including direct application of state of the art nuclei segmentation methods such as Cellpose and HoVer-Net, trained on H&E and a generative method, DeepLIIF, using two public IHC image datasets.

Stabilized Neural Ordinary Differential Equations for Long-Time Forecasting of Dynamical Systems

In data-driven modeling of spatiotemporal phenomena careful consideration often needs to be made in capturing the dynamics of the high wavenumbers. This problem becomes especially challenging when the system of interest exhibits shocks or chaotic dynamics. We present a data-driven modeling method that accurately captures shocks and chaotic dynamics by proposing a novel architecture, stabilized neural ordinary differential equation (ODE). In our proposed architecture, we learn the right-hand-side (RHS) of an ODE by adding the outputs of two NN together where one learns a linear term and the other a nonlinear term. Specifically, we implement this by training a sparse linear convolutional NN to learn the linear term and a dense fully-connected nonlinear NN to learn the nonlinear term. This is in contrast with the standard neural ODE which involves training only a single NN for learning the RHS. We apply this setup to the viscous Burgers equation, which exhibits shocked behavior, and show better short-time tracking and prediction of the energy spectrum at high wavenumbers than a standard neural ODE. We also find that the stabilized neural ODE models are much more robust to noisy initial conditions than the standard neural ODE approach. We also apply this method to chaotic trajectories of the Kuramoto-Sivashinsky equation. In this case, stabilized neural ODEs keep long-time trajectories on the attractor, and are highly robust to noisy initial conditions, while standard neural ODEs fail at achieving either of these results. We conclude by demonstrating how stabilizing neural ODEs provide a natural extension for use in reduced-order modeling by projecting the dynamics onto the eigenvectors of the learned linear term.

Artificial Neural Network and its Application Research Progress in Distillation

Artificial neural networks learn various rules and algorithms to form different ways of processing information, and have been widely used in various chemical processes. Among them, with the development of rectification technology, its production scale continues to expand, and its calculation requirements are also more stringent, because the artificial neural network has the advantages of self-learning, associative storage and high-speed search for optimized solutions, it can make high-precision simulation predictions for rectification operations, so it is widely used in the chemical field of rectification. This article gives a basic overview of artificial neural networks, and introduces the application research of artificial neural networks in distillation at home and abroad.

BridgeNet: A Joint Learning Network of Depth Map Super-Resolution and Monocular Depth Estimation

Depth map super-resolution is a task with high practical application requirements in the industry. Existing color-guided depth map super-resolution methods usually necessitate an extra branch to extract high-frequency detail information from RGB image to guide the low-resolution depth map reconstruction. However, because there are still some differences between the two modalities, direct information transmission in the feature dimension or edge map dimension cannot achieve satisfactory result, and may even trigger texture copying in areas where the structures of the RGB-D pair are inconsistent. Inspired by the multi-task learning, we propose a joint learning network of depth map super-resolution (DSR) and monocular depth estimation (MDE) without introducing additional supervision labels. For the interaction of two subnetworks, we adopt a differentiated guidance strategy and design two bridges correspondingly. One is the high-frequency attention bridge (HABdg) designed for the feature encoding process, which learns the high-frequency information of the MDE task to guide the DSR task. The other is the content guidance bridge (CGBdg) designed for the depth map reconstruction process, which provides the content guidance learned from DSR task for MDE task. The entire network architecture is highly portable and can provide a paradigm for associating the DSR and MDE tasks. Extensive experiments on benchmark datasets demonstrate that our method achieves competitive performance. Our code and models are available at https://rmcong.github.io/proj_BridgeNet.html.

Prediction of financial time series using LSTM and data denoising methods

In order to further overcome the difficulties of the existing models in dealing with the non-stationary and nonlinear characteristics of high-frequency financial time series data, especially its weak generalization ability, this paper proposes an ensemble method based on data denoising methods, including the wavelet transform (WT) and singular spectrum analysis (SSA), and long-term short-term memory neural network (LSTM) to build a data prediction model, The financial time series is decomposed and reconstructed by WT and SSA to denoise. Under the condition of denoising, the smooth sequence with effective information is reconstructed. The smoothing sequence is introduced into LSTM and the predicted value is obtained. With the Dow Jones industrial average index (DJIA) as the research object, the closing price of the DJIA every five minutes is divided into short-term (1 hour), medium-term (3 hours) and long-term (6 hours) respectively. . Based on root mean square error (RMSE), mean absolute error (MAE), mean absolute percentage error (MAPE) and absolute percentage error standard deviation (SDAPE), the experimental results show that in the short-term, medium-term and long-term, data denoising can greatly improve the accuracy and stability of the prediction, and can effectively improve the generalization ability of LSTM prediction model. As WT and SSA can extract useful information from the original sequence and avoid overfitting, the hybrid model can better grasp the sequence pattern of the closing price of the DJIA. And the WT-LSTM model is better than the benchmark LSTM model and SSA-LSTM model.

Deep Learning Derived Histopathology Image Score for Increasing Phase 3 Clinical Trial Probability of Success

Failures in Phase 3 clinical trials contribute to expensive cost of drug development in oncology. To drastically reduce such cost, responders to an oncology treatment need to be identified early on in the drug development process with limited amount of patient data before the planning of Phase 3 clinical trials. Despite the challenge of small sample size, we pioneered the use of deep-learning derived digital pathology scores to identify responders based on the immunohistochemistry images of the target antigen expressed in tumor biopsy samples from a Phase 1 Non-small Cell Lung Cancer clinical trial. Based on repeated 10-fold cross validations, the deep-learning derived score on average achieved 4% higher AUC of ROC curve and 6% higher AUC of Precision-Recall curve comparing to the tumor proportion score (TPS) based clinical benchmark. In a small independent testing set of patients, we also demonstrated that the deep-learning derived score achieved numerically at least 25% higher responder rate in the enriched population than the TPS clinical benchmark.

EasyQuant: Post-training Quantization via Scale Optimization

The 8 bits quantization has been widely applied to accelerate network inference in various deep learning applications. There are two kinds of quantization methods, training-based quantization and post-training quantization. Training-based approach suffers from a cumbersome training process, while post-training quantization may lead to unacceptable accuracy drop. In this paper, we present an efficient and simple post-training method via scale optimization, named EasyQuant (EQ),that could obtain comparable accuracy with the training-based method.Specifically, we first alternately optimize scales of weights and activations for all layers target at convolutional outputs to further obtain the high quantization precision. Then, we lower down bit width to INT7 both for weights and activations, and adopt INT16 intermediate storage and integer Winograd convolution implementation to accelerate inference.Experimental results on various computer vision tasks show that EQ outperforms the TensorRT method and can achieve near INT8 accuracy in 7 bits width post-training.