All in One: Generative Modeling as Mean-Field Game Design

Mean-field games (MFGs) offer a unifying lens on continuous-time generative modeling: a cost tuple recovering twelve prominent models---Continuous Normalizing Flows, OT-Flow, Score-based Models, Schrödinger Bridges, and more---as special cases of one variational problem. Yet two dimensions of this space remain entirely unexplored: the interaction term $\mathcal{I}$ is set to zero in many existing models, and the rich family of MFG solvers has never been applied to generative modeling. We address both gaps with MFGLab an open-source PyTorch library whose primary API is the cost tuple: all twelve models are specified by four composable cost functions, and the training loop, log-Jacobian, and reverse-ODE sampler are shared automatically. We additionally propose DI-Flow, a novel cost design that uses a differentiable entropy functional to encourage mode coverage, and provide learning-based MFG solvers that substantially outperform neural training on stochastic-dynamics rows. Experiments on two 2-D benchmarks confirm that the unified API is lossless relative to hand-coded implementations.

Multi-Agent Privacy Game in Federated Learning: A Unified Mean-Field View

Federated learning enables collaborative model training across distributed clients without centralising their data, yet privacy remains a persistent concern because the shared model updates can leak information about local datasets. Existing privacy-preserving methods either inject calibrated noise into client updates, limiting their composition guarantees, or formulate client privacy choices as a multi-agent game whose Nash equilibrium becomes intractable as the number of clients grows. We bridge these two lines of work by formulating privacy-preserving federated learning as a mean-field privacy game: each client strategically chooses its own privacy budget while interacting with the population only through a single mean-field statistic. The mean-field limit yields a tractable equilibrium for arbitrarily many clients, accommodates heterogeneous client preferences, and inherits an exponentially decaying privacy guarantee through a log-Sobolev contraction. The framework recovers the entropic privacy baseline as the homogeneous special case and the multi-agent privacy game as the finite-population case. Experiments on quadratic regression, logistic regression, and MNIST demonstrate that the proposed framework attains the privacy-utility trade-off of the entropic baseline while delivering a personalized privacy guarantee that the homogeneous baseline cannot express.

How Does Urban Context Relate to Residential Building Health? A Vision-POI Fusion Framework for Building-Level Housing Inspection

Housing-level urban physical examination is essential for identifying residential building problems and supporting targeted urban renewal. Existing automated inspection studies primarily rely on individual images and rarely examine whether surrounding urban functional context can provide supplementary information for building-level assessment. This study proposes a vision-POI fusion framework that combines multi-view visual inspection with POI-derived neighborhood context for residential building health assessment. The empirical dataset covers 92 old residential communities, 3,237 residential buildings, and 25,608 field-acquired inspection images in Qingdao, China, encompassing seven categories of housing-related issues. First, multiple object detection models are evaluated to extract issue locations, categories, and confidence scores from individual images. The image-level outputs are subsequently aggregated across multiple views to construct interpretable building-level representations. Second, POI features are extracted within 500m, 1,000m, and 1,500m neighborhood buffers to characterize surrounding functional environments. Pearson and Spearman correlation analyses, combined with false discovery rate correction, are used to identify candidate contextual features. Finally, visual and POI features are integrated using a cost-sensitive Random Forest classifier under community-isolated spatial cross-validation. The results show that multi-view aggregation provides the main performance improvement, increasing the building-level Macro-F1 from 60.84% under Direct Detection to 74.95%. Incorporating POI context further increases Macro-F1 to 76.79%, although the additional gain is modest and category-dependent. POI information therefore functions as a supplementary contextual prior rather than a substitute for direct visual evidence or a causal determinant of building condition.

Artemis: Anatomy-Resolved inTervention for Eliminating Multimodal NeuroImage confounderS

Multimodal neuroimaging, integrating functional connectivity from fMRI and structural connectivity from DTI, enables non-invasive analysis of brain networks using graph neural networks. However, demographic factors such as age and sex systematically confound the relationship between brain connectivity and clinical outcomes, causing GNNs to exploit spurious shortcuts rather than learning causally invariant representations. While recent causal GNN methods introduce causality at the graph-modeling level, their causal mechanisms remain domain-agnostic without accounting for the real-world confounders inherent in clinical neuroimaging data. Moreover, brain networks are constructed from atlas-based parcellations where each region exhibits distinct sensitivity to demographic factors, necessitating region-aware adjustment. We propose Artemis, a region-level causal framework that bridges this gap with causal intervention at each brain region independently by learning region-specific confounder representations with lightweight parameters. Our adjustment comprehensively utilized the multimodal functional and structural features for graph reasoning as a plug-in module compatible with arbitrary GNN backbones. Experiments on three benchmarks, ADNI for disease diagnosis, OASIS for dementia staging, and HCP for sex classification, demonstrate consistent improvements over representative GNN-based baselines. Multiple supporting experiments further demonstrate statistical significance and neuroscientific interpretability.

Listen, Look, Drive: Coupling Audio Instructions for User-aware VLA-based Autonomous Driving

Vision Language Action (VLA) models promise an open-vocabulary interface that can translate perceptual ambiguity into semantically grounded driving decisions, yet they still treat language as a static prior fixed at inference time. As a result, the model must infer continuously shifting objectives from pixels alone, yielding delayed or overly conservative maneuvers. We argue that effective VLAs for autonomous driving need an online channel in which users can influence driving with specific intentions. To this end, we present EchoVLA, a user-aware VLA that couples camera streams with in situ audio instructions. We augment the nuScenes dataset with temporally aligned, intent-specific speech commands generated by converting ego-motion descriptions into synthetic audios. Further, we compose emotional speech-trajectory pairs into a multimodal Chain-of-Thought (CoT) for fine-tuning a Multimodal Large Model (MLM) based on Qwen2.5-Omni. Specifically, we synthesize the audio-augmented dataset with different emotion types paired with corresponding driving behaviors, leveraging the emotional cues embedded in tone, pitch, and speech tempo to reflect varying user states, such as urgent or hesitant intentions, thus enabling our EchoVLA to interpret not only the semantic content but also the emotional context of audio commands for more nuanced and emotionally adaptive driving behavior. In open-loop benchmarks, our approach reduces the average L2 error by $59.4\%$ and the collision rate by $74.4\%$ compared to the baseline of vision-only perception. More experiments on nuScenes dataset validate that EchoVLA not only steers the trajectory through audio instructions, but also modulates driving behavior in response to the emotions detected in the user's speech.

FigEx2: Visual-Conditioned Panel Detection and Captioning for Scientific Compound Figures

Scientific compound figures combine multiple labeled panels into a single image, but captions in real pipelines are often missing or only provide figure-level summaries, making panel-level understanding difficult. In this paper, we propose FigEx2, visual-conditioned framework that localizes panels and generates panel-wise captions directly from the compound figure. To mitigate the impact of diverse phrasing in open-ended captioning, we introduce a noise-aware gated fusion module that adaptively filters token-level features to stabilize the detection query space. Furthermore, we employ a staged optimization strategy combining supervised learning with reinforcement learning (RL), utilizing CLIP-based alignment and BERTScore-based semantic rewards to enforce strict multimodal consistency. To support high-quality supervision, we curate BioSci-Fig-Cap, a refined benchmark for panel-level grounding, alongside cross-disciplinary test suites in physics and chemistry. Experimental results demonstrate that FigEx2 achieves a superior 0.726 mAP@0.5:0.95 for detection and significantly outperforms Qwen3-VL-8B by 0.51 in METEOR and 0.24 in BERTScore. Notably, FigEx2 exhibits remarkable zero-shot transferability to out-of-distribution scientific domains without any fine-tuning.

Aligning Findings with Diagnosis: A Self-Consistent Reinforcement Learning Framework for Trustworthy Radiology Reporting

Multimodal Large Language Models (MLLMs) have shown strong potential for radiology report generation, yet their clinical translation is hindered by architectural heterogeneity and the prevalence of factual hallucinations. Standard supervised fine-tuning often fails to strictly align linguistic outputs with visual evidence, while existing reinforcement learning approaches struggle with either prohibitive computational costs or limited exploration. To address these challenges, we propose a comprehensive framework for self-consistent radiology report generation. First, we conduct a systematic evaluation to identify optimal vision encoder and LLM backbone configurations for medical imaging. Building on this foundation, we introduce a novel "Reason-then-Summarize" architecture optimized via Group Relative Policy Optimization (GRPO). This framework restructures generation into two distinct components: a think block for detailed findings and an answer block for structured disease labels. By utilizing a multi-dimensional composite reward function, we explicitly penalize logical discrepancies between the generated narrative and the final diagnosis. Extensive experiments on the MIMIC-CXR benchmark demonstrate that our method achieves state-of-the-art performance in clinical efficacy metrics and significantly reduces hallucinations compared to strong supervised baselines.

R-GenIMA: Integrating Neuroimaging and Genetics with Interpretable Multimodal AI for Alzheimer's Disease Progression

Early detection of Alzheimer's disease (AD) requires models capable of integrating macro-scale neuroanatomical alterations with micro-scale genetic susceptibility, yet existing multimodal approaches struggle to align these heterogeneous signals. We introduce R-GenIMA, an interpretable multimodal large language model that couples a novel ROI-wise vision transformer with genetic prompting to jointly model structural MRI and single nucleotide polymorphisms (SNPs) variations. By representing each anatomically parcellated brain region as a visual token and encoding SNP profiles as structured text, the framework enables cross-modal attention that links regional atrophy patterns to underlying genetic factors. Applied to the ADNI cohort, R-GenIMA achieves state-of-the-art performance in four-way classification across normal cognition (NC), subjective memory concerns (SMC), mild cognitive impairment (MCI), and AD. Beyond predictive accuracy, the model yields biologically meaningful explanations by identifying stage-specific brain regions and gene signatures, as well as coherent ROI-Gene association patterns across the disease continuum. Attention-based attribution revealed genes consistently enriched for established GWAS-supported AD risk loci, including APOE, BIN1, CLU, and RBFOX1. Stage-resolved neuroanatomical signatures identified shared vulnerability hubs across disease stages alongside stage-specific patterns: striatal involvement in subjective decline, frontotemporal engagement during prodromal impairment, and consolidated multimodal network disruption in AD. These results demonstrate that interpretable multimodal AI can synthesize imaging and genetics to reveal mechanistic insights, providing a foundation for clinically deployable tools that enable earlier risk stratification and inform precision therapeutic strategies in Alzheimer's disease.

Why Text Prevails: Vision May Undermine Multimodal Medical Decision Making

With the rapid progress of large language models (LLMs), advanced multimodal large language models (MLLMs) have demonstrated impressive zero-shot capabilities on vision-language tasks. In the biomedical domain, however, even state-of-the-art MLLMs struggle with basic Medical Decision Making (MDM) tasks. We investigate this limitation using two challenging datasets: (1) three-stage Alzheimer's disease (AD) classification (normal, mild cognitive impairment, dementia), where category differences are visually subtle, and (2) MIMIC-CXR chest radiograph classification with 14 non-mutually exclusive conditions. Our empirical study shows that text-only reasoning consistently outperforms vision-only or vision-text settings, with multimodal inputs often performing worse than text alone. To mitigate this, we explore three strategies: (1) in-context learning with reason-annotated exemplars, (2) vision captioning followed by text-only inference, and (3) few-shot fine-tuning of the vision tower with classification supervision. These findings reveal that current MLLMs lack grounded visual understanding and point to promising directions for improving multimodal decision making in healthcare.

DRE: An Effective Dual-Refined Method for Integrating Small and Large Language Models in Open-Domain Dialogue Evaluation

Large Language Models (LLMs) excel at many tasks but struggle with ambiguous scenarios where multiple valid responses exist, often yielding unreliable results. Conversely, Small Language Models (SLMs) demonstrate robustness in such scenarios but are susceptible to misleading or adversarial inputs. We observed that LLMs handle negative examples effectively, while SLMs excel with positive examples. To leverage their complementary strengths, we introduce SLIDE (Small and Large Integrated for Dialogue Evaluation), a method integrating SLMs and LLMs via adaptive weighting. Building on SLIDE, we further propose a Dual-Refinement Evaluation (DRE) method to enhance SLM-LLM integration: (1) SLM-generated insights guide the LLM to produce initial evaluations; (2) SLM-derived adjustments refine the LLM's scores for improved accuracy. Experiments demonstrate that DRE outperforms existing methods, showing stronger alignment with human judgment across diverse benchmarks. This work illustrates how combining small and large models can yield more reliable evaluation tools, particularly for open-ended tasks such as dialogue evaluation.