BioT5: Enriching Cross-modal Integration in Biology with Chemical Knowledge and Natural Language Associations

Recent advancements in biological research leverage the integration of molecules, proteins, and natural language to enhance drug discovery. However, current models exhibit several limitations, such as the generation of invalid molecular SMILES, underutilization of contextual information, and equal treatment of structured and unstructured knowledge. To address these issues, we propose $\mathbf{BioT5}$, a comprehensive pre-training framework that enriches cross-modal integration in biology with chemical knowledge and natural language associations. $\mathbf{BioT5}$ utilizes SELFIES for $100%$ robust molecular representations and extracts knowledge from the surrounding context of bio-entities in unstructured biological literature. Furthermore, $\mathbf{BioT5}$ distinguishes between structured and unstructured knowledge, leading to more effective utilization of information. After fine-tuning, BioT5 shows superior performance across a wide range of tasks, demonstrating its strong capability of capturing underlying relations and properties of bio-entities. Our code is available at $\href{https://github.com/QizhiPei/BioT5}{Github}$.

Human Respiration Detection Under Interference: Challenges and Solutions

Recent research has highlighted the detection of human respiration rate using commodity WiFi devices. Nevertheless, these devices encounter challenges in accurately discerning human respiration amidst the prevailing human motion interference encountered in daily life. To tackle this predicament, this paper introduces a passive sensing and communication system designed specifically for respiration detection in the presence of robust human motion interference. Operating within the 60.48GHz band, the proposed system aims to detect human respiration even when confronted with substantial human motion interference within close proximity. Subsequently, a neural network is trained using the collected data by us to enable human respiration detection. The experimental results demonstrate a consistently high accuracy rate over 90\% of the human respiration detection under interference, given an adequate sensing duration. Finally, an empirical model is derived analytically to achieve the respiratory rate counting in 10 seconds.