Foundation Model for Advancing Healthcare: Challenges, Opportunities, and Future Directions

Foundation model, which is pre-trained on broad data and is able to adapt to a wide range of tasks, is advancing healthcare. It promotes the development of healthcare artificial intelligence (AI) models, breaking the contradiction between limited AI models and diverse healthcare practices. Much more widespread healthcare scenarios will benefit from the development of a healthcare foundation model (HFM), improving their advanced intelligent healthcare services. Despite the impending widespread deployment of HFMs, there is currently a lack of clear understanding about how they work in the healthcare field, their current challenges, and where they are headed in the future. To answer these questions, a comprehensive and deep survey of the challenges, opportunities, and future directions of HFMs is presented in this survey. It first conducted a comprehensive overview of the HFM including the methods, data, and applications for a quick grasp of the current progress. Then, it made an in-depth exploration of the challenges present in data, algorithms, and computing infrastructures for constructing and widespread application of foundation models in healthcare. This survey also identifies emerging and promising directions in this field for future development. We believe that this survey will enhance the community's comprehension of the current progress of HFM and serve as a valuable source of guidance for future development in this field. The latest HFM papers and related resources are maintained on our website: https://github.com/YutingHe-list/Awesome-Foundation-Models-for-Advancing-Healthcare.

An Open-World, Diverse, Cross-Spatial-Temporal Benchmark for Dynamic Wild Person Re-Identification

Person re-identification (ReID) has made great strides thanks to the data-driven deep learning techniques. However, the existing benchmark datasets lack diversity, and models trained on these data cannot generalize well to dynamic wild scenarios. To meet the goal of improving the explicit generalization of ReID models, we develop a new Open-World, Diverse, Cross-Spatial-Temporal dataset named OWD with several distinct features. 1) Diverse collection scenes: multiple independent open-world and highly dynamic collecting scenes, including streets, intersections, shopping malls, etc. 2) Diverse lighting variations: long time spans from daytime to nighttime with abundant illumination changes. 3) Diverse person status: multiple camera networks in all seasons with normal/adverse weather conditions and diverse pedestrian appearances (e.g., clothes, personal belongings, poses, etc.). 4) Protected privacy: invisible faces for privacy critical applications. To improve the implicit generalization of ReID, we further propose a Latent Domain Expansion (LDE) method to develop the potential of source data, which decouples discriminative identity-relevant and trustworthy domain-relevant features and implicitly enforces domain-randomized identity feature space expansion with richer domain diversity to facilitate domain invariant representations. Our comprehensive evaluations with most benchmark datasets in the community are crucial for progress, although this work is far from the grand goal toward open-world and dynamic wild applications.

Dynamic Weighted Combiner for Mixed-Modal Image Retrieval

Mixed-Modal Image Retrieval (MMIR) as a flexible search paradigm has attracted wide attention. However, previous approaches always achieve limited performance, due to two critical factors are seriously overlooked. 1) The contribution of image and text modalities is different, but incorrectly treated equally. 2) There exist inherent labeling noises in describing users' intentions with text in web datasets from diverse real-world scenarios, giving rise to overfitting. We propose a Dynamic Weighted Combiner (DWC) to tackle the above challenges, which includes three merits. First, we propose an Editable Modality De-equalizer (EMD) by taking into account the contribution disparity between modalities, containing two modality feature editors and an adaptive weighted combiner. Second, to alleviate labeling noises and data bias, we propose a dynamic soft-similarity label generator (SSG) to implicitly improve noisy supervision. Finally, to bridge modality gaps and facilitate similarity learning, we propose a CLIP-based mutual enhancement module alternately trained by a mixed-modality contrastive loss. Extensive experiments verify that our proposed model significantly outperforms state-of-the-art methods on real-world datasets. The source code is available at \url{https://github.com/fuxianghuang1/DWC}.

Language Guided Local Infiltration for Interactive Image Retrieval

Interactive Image Retrieval (IIR) aims to retrieve images that are generally similar to the reference image but under the requested text modification. The existing methods usually concatenate or sum the features of image and text simply and roughly, which, however, is difficult to precisely change the local semantics of the image that the text intends to modify. To solve this problem, we propose a Language Guided Local Infiltration (LGLI) system, which fully utilizes the text information and penetrates text features into image features as much as possible. Specifically, we first propose a Language Prompt Visual Localization (LPVL) module to generate a localization mask which explicitly locates the region (semantics) intended to be modified. Then we introduce a Text Infiltration with Local Awareness (TILA) module, which is deployed in the network to precisely modify the reference image and generate image-text infiltrated representation. Extensive experiments on various benchmark databases validate that our method outperforms most state-of-the-art IIR approaches.

Probability Weighted Compact Feature for Domain Adaptive Retrieval

Domain adaptive image retrieval includes single-domain retrieval and cross-domain retrieval. Most of the existing image retrieval methods only focus on single-domain retrieval, which assumes that the distributions of retrieval databases and queries are similar. However, in practical application, the discrepancies between retrieval databases often taken in ideal illumination/pose/background/camera conditions and queries usually obtained in uncontrolled conditions are very large. In this paper, considering the practical application, we focus on challenging cross-domain retrieval. To address the problem, we propose an effective method named Probability Weighted Compact Feature Learning (PWCF), which provides inter-domain correlation guidance to promote cross-domain retrieval accuracy and learns a series of compact binary codes to improve the retrieval speed. First, we derive our loss function through the Maximum A Posteriori Estimation (MAP): Bayesian Perspective (BP) induced focal-triplet loss, BP induced quantization loss and BP induced classification loss. Second, we propose a common manifold structure between domains to explore the potential correlation across domains. Considering the original feature representation is biased due to the inter-domain discrepancy, the manifold structure is difficult to be constructed. Therefore, we propose a new feature named Histogram Feature of Neighbors (HFON) from the sample statistics perspective. Extensive experiments on various benchmark databases validate that our method outperforms many state-of-the-art image retrieval methods for domain adaptive image retrieval. The source code is available at https://github.com/fuxianghuang1/PWCF