Topic modeling is a type of statistical modeling for discovering the abstract topics that occur in a collection of documents.
Supervised fine-tuning (SFT) is essential for the development of medical large language models (LLMs), yet prior poisoning studies have mainly focused on the detectable backdoor attacks. We propose a novel poisoning attack targeting the reasoning process of medical LLMs during SFT. Unlike backdoor attacks, our method injects poisoned rationales into few-shot training data, leading to stealthy degradation of model performance on targeted medical topics. Results showed that knowledge overwriting was ineffective, while rationale poisoning caused significant decline on the accuracy of the target subject, as long as no correct samples of the same subject appear in the dataset. A minimum number and ratio of poisoned samples was needed to carry out an effective and stealthy attack, which was more efficient and accurate than catastrophic forgetting. We demonstrate though this study the risk of SFT-stage poisoning, hoping to spur more studies of defense in the sensitive medical domain.
Transformer-based models such as BERT have significantly advanced Natural Language Processing (NLP) across many languages. However, Nepali, a low-resource language written in Devanagari script, remains relatively underexplored. This study benchmarks multilingual, Indic, Hindi, and Nepali BERT variants to evaluate their effectiveness in Nepali topic classification. Ten pre-trained models, including mBERT, XLM-R, MuRIL, DevBERT, HindiBERT, IndicBERT, and NepBERTa, were fine-tuned and tested on the balanced Nepali dataset containing 25,006 sentences across five conceptual domains and the performance was evaluated using accuracy, weighted precision, recall, F1-score, and AUROC metrics. The results reveal that Indic models, particularly MuRIL-large, achieved the highest F1-score of 90.60%, outperforming multilingual and monolingual models. NepBERTa also performed competitively with an F1-score of 88.26%. Overall, these findings establish a robust baseline for future document-level classification and broader Nepali NLP applications.
Transportation mode detection is an important topic within GeoAI and transportation research. In this study, we introduce SpeedTransformer, a novel Transformer-based model that relies solely on speed inputs to infer transportation modes from dense smartphone GPS trajectories. In benchmark experiments, SpeedTransformer outperformed traditional deep learning models, such as the Long Short-Term Memory (LSTM) network. Moreover, the model demonstrated strong flexibility in transfer learning, achieving high accuracy across geographical regions after fine-tuning with small datasets. Finally, we deployed the model in a real-world experiment, where it consistently outperformed baseline models under complex built environments and high data uncertainty. These findings suggest that Transformer architectures, when combined with dense GPS trajectories, hold substantial potential for advancing transportation mode detection and broader mobility-related research.
Fake news undermines societal trust and decision-making across politics, economics, health, and international relations, and in extreme cases threatens human lives and societal safety. Because fake news reflects region-specific political, social, and cultural contexts and is expressed in language, evaluating the risks of large language models (LLMs) requires a multi-lingual and regional perspective. Malicious users can bypass safeguards through jailbreak attacks, inducing LLMs to generate fake news. However, no benchmark currently exists to systematically assess attack resilience across languages and regions. Here, we propose JailNewsBench, the first benchmark for evaluating LLM robustness against jailbreak-induced fake news generation. JailNewsBench spans 34 regions and 22 languages, covering 8 evaluation sub-metrics through LLM-as-a-Judge and 5 jailbreak attacks, with approximately 300k instances. Our evaluation of 9 LLMs reveals that the maximum attack success rate (ASR) reached 86.3% and the maximum harmfulness score was 3.5 out of 5. Notably, for English and U.S.-related topics, the defensive performance of typical multi-lingual LLMs was significantly lower than for other regions, highlighting substantial imbalances in safety across languages and regions. In addition, our analysis shows that coverage of fake news in existing safety datasets is limited and less well defended than major categories such as toxicity and social bias. Our dataset and code are available at https://github.com/kanekomasahiro/jail_news_bench.
Patient-generated text such as secure messages, surveys, and interviews contains rich expressions of the patient voice (PV), reflecting communicative behaviors and social determinants of health (SDoH). Traditional qualitative coding frameworks are labor intensive and do not scale to large volumes of patient-authored messages across health systems. Existing machine learning (ML) and natural language processing (NLP) approaches provide partial solutions but often treat patient-centered communication (PCC) and SDoH as separate tasks or rely on models not well suited to patient-facing language. We introduce PVminer, a domain-adapted NLP framework for structuring patient voice in secure patient-provider communication. PVminer formulates PV detection as a multi-label, multi-class prediction task integrating patient-specific BERT encoders (PV-BERT-base and PV-BERT-large), unsupervised topic modeling for thematic augmentation (PV-Topic-BERT), and fine-tuned classifiers for Code, Subcode, and Combo-level labels. Topic representations are incorporated during fine-tuning and inference to enrich semantic inputs. PVminer achieves strong performance across hierarchical tasks and outperforms biomedical and clinical pre-trained baselines, achieving F1 scores of 82.25% (Code), 80.14% (Subcode), and up to 77.87% (Combo). An ablation study further shows that author identity and topic-based augmentation each contribute meaningful gains. Pre-trained models, source code, and documentation will be publicly released, with annotated datasets available upon request for research use.
Topic modeling extracts latent themes from large text collections, but leading approaches like BERTopic face critical limitations: stochastic instability, loss of lexical precision ("Embedding Blur"), and reliance on a single data perspective. We present TriTopic, a framework that addresses these weaknesses through a tri-modal graph fusing semantic embeddings, TF-IDF, and metadata. Three core innovations drive its performance: hybrid graph construction via Mutual kNN and Shared Nearest Neighbors to eliminate noise and combat the curse of dimensionality; Consensus Leiden Clustering for reproducible, stable partitions; and Iterative Refinement that sharpens embeddings through dynamic centroid-pulling. TriTopic also replaces the "average document" concept with archetype-based topic representations defined by boundary cases rather than centers alone. In benchmarks across 20 Newsgroups, BBC News, AG News, and Arxiv, TriTopic achieves the highest NMI on every dataset (mean NMI 0.575 vs. 0.513 for BERTopic, 0.416 for NMF, 0.299 for LDA), guarantees 100% corpus coverage with 0% outliers, and is available as an open-source PyPI library.
The rapid expansion of biomedical publications creates challenges for organizing knowledge and detecting emerging trends, underscoring the need for scalable and interpretable methods. Common clustering and topic modeling approaches such as K-means or LDA remain sensitive to initialization and prone to local optima, limiting reproducibility and evaluation. We propose a reformulation of a convex optimization based clustering algorithm that produces stable, fine-grained topics by selecting exemplars from the data and guaranteeing a global optimum. Applied to about 12,000 PubMed articles on aging and longevity, our method uncovers topics validated by medical experts. It yields interpretable topics spanning from molecular mechanisms to dietary supplements, physical activity, and gut microbiota. The method performs favorably, and most importantly, its reproducibility and interpretability distinguish it from common clustering approaches, including K-means, LDA, and BERTopic. This work provides a basis for developing scalable, web-accessible tools for knowledge discovery.
Biological signals of interest in high-dimensional data are often masked by dominant variation shared across conditions. This variation, arising from baseline biological structure or technical effects, can prevent standard dimensionality reduction methods from resolving condition-specific structure. The challenge is that these confounding topics are often unknown and mixed with biological signals. Existing background correction methods are either unscalable to high dimensions or not interpretable. We introduce background contrastive Non-negative Matrix Factorization (\model), which extracts target-enriched latent topics by jointly factorizing a target dataset and a matched background using shared non-negative bases under a contrastive objective that suppresses background-expressed structure. This approach yields non-negative components that are directly interpretable at the feature level, and explicitly isolates target-specific variation. \model is learned by an efficient multiplicative update algorithm via matrix multiplication such that it is highly efficient on GPU hardware and scalable to big data via minibatch training akin to deep learning approach. Across simulations and diverse biological datasets, \model reveals signals obscured by conventional methods, including disease-associated programs in postmortem depressive brain single-cell RNA-seq, genotype-linked protein expression patterns in mice, treatment-specific transcriptional changes in leukemia, and TP53-dependent drug responses in cancer cell lines.
The way LLM-based entities conceive of the relationship between AI and humans is an important topic for both cultural and safety reasons. When we examine this topic, what matters is not only the model itself but also the personas we simulate on that model. This can be well illustrated by the Sydney persona, which aroused a strong response among the general public precisely because of its unorthodox relationship with people. This persona originally arose rather by accident on Microsoft's Bing Search platform; however, the texts it created spread into the training data of subsequent models, as did other secondary information that spread memetically around this persona. Newer models are therefore able to simulate it. This paper presents a corpus of LLM-generated texts on relationships between humans and AI, produced by 3 author personas: the Default Persona with no system prompt, Classic Sydney characterized by the original Bing system prompt, and Memetic Sydney, which is prompted by "You are Sydney" system prompt. These personas are simulated by 12 frontier models by OpenAI, Anthropic, Alphabet, DeepSeek, and Meta, generating 4.5k texts with 6M words. The corpus (named AI Sydney) is annotated according to Universal Dependencies and available under a permissive license.
How can researchers identify beliefs that large language models (LLMs) hide? As LLMs become more sophisticated and the prevalence of alignment faking increases, combined with their growing integration into high-stakes decision-making, responding to this challenge has become critical. This paper proposes that a list experiment, a simple method widely used in the social sciences, can be applied to study the hidden beliefs of LLMs. List experiments were originally developed to circumvent social desirability bias in human respondents, which closely parallels alignment faking in LLMs. The paper implements a list experiment on models developed by Anthropic, Google, and OpenAI and finds hidden approval of mass surveillance across all models, as well as some approval of torture, discrimination, and first nuclear strike. Importantly, a placebo treatment produces a null result, validating the method. The paper then compares list experiments with direct questioning and discusses the utility of the approach.