LEFT: Learnable Fusion of Tri-view Tokens for Unsupervised Time Series Anomaly Detection

As a fundamental data mining task, unsupervised time series anomaly detection (TSAD) aims to build a model for identifying abnormal timestamps without assuming the availability of annotations. A key challenge in unsupervised TSAD is that many anomalies are too subtle to exhibit detectable deviation in any single view (e.g., time domain), and instead manifest as inconsistencies across multiple views like time, frequency, and a mixture of resolutions. However, most cross-view methods rely on feature or score fusion and do not enforce analysis-synthesis consistency, meaning the frequency branch is not required to reconstruct the time signal through an inverse transform, and vice versa. In this paper, we present Learnable Fusion of Tri-view Tokens (LEFT), a unified unsupervised TSAD framework that models anomalies as inconsistencies across complementary representations. LEFT learns feature tokens from three views of the same input time series: frequency-domain tokens that embed periodicity information, time-domain tokens that capture local dynamics, and multi-scale tokens that learns abnormal patterns at varying time series granularities. By learning a set of adaptive Nyquist-constrained spectral filters, the original time series is rescaled into multiple resolutions and then encoded, allowing these multi-scale tokens to complement the extracted frequency- and time-domain information. When generating the fused representation, we introduce a novel objective that reconstructs fine-grained targets from coarser multi-scale structure, and put forward an innovative time-frequency cycle consistency constraint to explicitly regularize cross-view agreement. Experiments on real-world benchmarks show that LEFT yields the best detection accuracy against SOTA baselines, while achieving a 5x reduction on FLOPs and 8x speed-up for training.

AnomaMind: Agentic Time Series Anomaly Detection with Tool-Augmented Reasoning

Time series anomaly detection is critical in many real-world applications, where effective solutions must localize anomalous regions and support reliable decision-making under complex settings. However, most existing methods frame anomaly detection as a purely discriminative prediction task with fixed feature inputs, rather than an evidence-driven diagnostic process. As a result, they often struggle when anomalies exhibit strong context dependence or diverse patterns. We argue that these limitations stem from the lack of adaptive feature preparation, reasoning-aware detection, and iterative refinement during inference. To address these challenges, we propose AnomaMind, an agentic time series anomaly detection framework that reformulates anomaly detection as a sequential decision-making process. AnomaMind operates through a structured workflow that progressively localizes anomalous intervals in a coarse-to-fine manner, augments detection through multi-turn tool interactions for adaptive feature preparation, and refines anomaly decisions via self-reflection. The workflow is supported by a set of reusable tool engines, enabling context-aware diagnostic analysis. A key design of AnomaMind is an explicitly designed hybrid inference mechanism for tool-augmented anomaly detection. In this mechanism, general-purpose models are responsible for autonomous tool interaction and self-reflective refinement, while core anomaly detection decisions are learned through reinforcement learning under verifiable workflow-level feedback, enabling task-specific optimization within a flexible reasoning framework. Extensive experiments across diverse settings demonstrate that AnomaMind consistently improves anomaly detection performance. The code is available at https://anonymous.4open.science/r/AnomaMind.

Locally Private Parametric Methods for Change-Point Detection

We study parametric change-point detection, where the goal is to identify distributional changes in time series, under local differential privacy. In the non-private setting, we derive improved finite-sample accuracy guarantees for a change-point detection algorithm based on the generalized log-likelihood ratio test, via martingale methods. In the private setting, we propose two locally differentially private algorithms based on randomized response and binary mechanisms, and analyze their theoretical performance. We derive bounds on detection accuracy and validate our results through empirical evaluation. Our results characterize the statistical cost of local differential privacy in change-point detection and show how privacy degrades performance relative to a non-private benchmark. As part of this analysis, we establish a structural result for strong data processing inequalities (SDPI), proving that SDPI coefficients for Rényi divergences and their symmetric variants (Jeffreys-Rényi divergences) are achieved by binary input distributions. These results on SDPI coefficients are also of independent interest, with applications to statistical estimation, data compression, and Markov chain mixing.

NeuroMambaLLM: Dynamic Graph Learning of fMRI Functional Connectivity in Autistic Brains Using Mamba and Language Model Reasoning

Large Language Models (LLMs) have demonstrated strong semantic reasoning across multimodal domains. However, their integration with graph-based models of brain connectivity remains limited. In addition, most existing fMRI analysis methods rely on static Functional Connectivity (FC) representations, which obscure transient neural dynamics critical for neurodevelopmental disorders such as autism. Recent state-space approaches, including Mamba, model temporal structure efficiently, but are typically used as standalone feature extractors without explicit high-level reasoning. We propose NeuroMambaLLM, an end-to-end framework that integrates dynamic latent graph learning and selective state-space temporal modelling with LLMs. The proposed method learns the functional connectivity dynamically from raw Blood-Oxygen-Level-Dependent (BOLD) time series, replacing fixed correlation graphs with adaptive latent connectivity while suppressing motion-related artifacts and capturing long-range temporal dependencies. The resulting dynamic brain representations are projected into the embedding space of an LLM model, where the base language model remains frozen and lightweight low-rank adaptation (LoRA) modules are trained for parameter-efficient alignment. This design enables the LLM to perform both diagnostic classification and language-based reasoning, allowing it to analyze dynamic fMRI patterns and generate clinically meaningful textual reports.

Adaptive Structured Pruning of Convolutional Neural Networks for Time Series Classification

Deep learning models for Time Series Classification (TSC) have achieved strong predictive performance but their high computational and memory requirements often limit deployment on resource-constrained devices. While structured pruning can address these issues by removing redundant filters, existing methods typically rely on manually tuned hyperparameters such as pruning ratios which limit scalability and generalization across datasets. In this work, we propose Dynamic Structured Pruning (DSP), a fully automatic, structured pruning framework for convolution-based TSC models. DSP introduces an instance-wise sparsity loss during training to induce channel-level sparsity, followed by a global activation analysis to identify and prune redundant filters without needing any predefined pruning ratio. This work tackles computational bottlenecks of deep TSC models for deployment on resource-constrained devices. We validate DSP on 128 UCR datasets using two different deep state-of-the-art architectures: LITETime and InceptionTime. Our approach achieves an average compression of 58% for LITETime and 75% for InceptionTime architectures while maintaining classification accuracy. Redundancy analyses confirm that DSP produces compact and informative representations, offering a practical path for scalable and efficient deep TSC deployment.

Rethinking the Role of LLMs in Time Series Forecasting

Large language models (LLMs) have been introduced to time series forecasting (TSF) to incorporate contextual knowledge beyond numerical signals. However, existing studies question whether LLMs provide genuine benefits, often reporting comparable performance without LLMs. We show that such conclusions stem from limited evaluation settings and do not hold at scale. We conduct a large-scale study of LLM-based TSF (LLM4TSF) across 8 billion observations, 17 forecasting scenarios, 4 horizons, multiple alignment strategies, and both in-domain and out-of-domain settings. Our results demonstrate that \emph{LLM4TS indeed improves forecasting performance}, with especially large gains in cross-domain generalization. Pre-alignment outperforming post-alignment in over 90\% of tasks. Both pretrained knowledge and model architecture of LLMs contribute and play complementary roles: pretraining is critical under distribution shifts, while architecture excels at modeling complex temporal dynamics. Moreover, under large-scale mixed distributions, a fully intact LLM becomes indispensable, as confirmed by token-level routing analysis and prompt-based improvements. Overall, Our findings overturn prior negative assessments, establish clear conditions under which LLMs are not only useful, and provide practical guidance for effective model design. We release our code at https://github.com/EIT-NLP/LLM4TSF.

Deep Modeling and Interpretation for Bladder Cancer Classification

Deep models based on vision transformer (ViT) and convolutional neural network (CNN) have demonstrated remarkable performance on natural datasets. However, these models may not be similar in medical imaging, where abnormal regions cover only a small portion of the image. This challenge motivates this study to investigate the latest deep models for bladder cancer classification tasks. We propose the following to evaluate these deep models: 1) standard classification using 13 models (four CNNs and eight transormer-based models), 2) calibration analysis to examine if these models are well calibrated for bladder cancer classification, and 3) we use GradCAM++ to evaluate the interpretability of these models for clinical diagnosis. We simulate $\sim 300$ experiments on a publicly multicenter bladder cancer dataset, and the experimental results demonstrate that the ConvNext series indicate limited generalization ability to classify bladder cancer images (e.g., $\sim 60\%$ accuracy). In addition, ViTs show better calibration effects compared to ConvNext and swin transformer series. We also involve test time augmentation to improve the models interpretability. Finally, no model provides a one-size-fits-all solution for a feasible interpretable model. ConvNext series are suitable for in-distribution samples, while ViT and its variants are suitable for interpreting out-of-distribution samples.

Uncertainty in Federated Granger Causality: From Origins to Systemic Consequences

Granger Causality (GC) provides a rigorous framework for learning causal structures from time-series data. Recent federated variants of GC have targeted distributed infrastructure applications (e.g., smart grids) with distributed clients that generate high-dimensional data bound by data-sovereignty constraints. However, Federated GC algorithms only yield deterministic point estimates of causality and neglect uncertainty. This paper establishes the first methodology for rigorously quantifying uncertainty and its propagation within federated GC frameworks. We systematically classify sources of uncertainty, explicitly differentiating aleatoric (data noise) from epistemic (model variability) effects. We derive closed-form recursions that model the evolution of uncertainty through client-server interactions and identify four novel cross-covariance components that couple data uncertainties with model parameter uncertainties across the federated architecture. We also define rigorous convergence conditions for these uncertainty recursions and obtain explicit steady-state variances for both server and client model parameters. Our convergence analysis demonstrates that steady-state variances depend exclusively on client data statistics, thus eliminating dependence on initial epistemic priors and enhancing robustness. Empirical evaluations on synthetic benchmarks and real-world industrial datasets demonstrate that explicitly characterizing uncertainty significantly improves the reliability and interpretability of federated causal inference.

Statistical benchmarking of transformer models in low signal-to-noise time-series forecasting

We study the performance of transformer architectures for multivariate time-series forecasting in low-data regimes consisting of only a few years of daily observations. Using synthetically generated processes with known temporal and cross-sectional dependency structures and varying signal-to-noise ratios, we conduct bootstrapped experiments that enable direct evaluation via out-of-sample correlations with the optimal ground-truth predictor. We show that two-way attention transformers, which alternate between temporal and cross-sectional self-attention, can outperform standard baselines-Lasso, boosting methods, and fully connected multilayer perceptrons-across a wide range of settings, including low signal-to-noise regimes. We further introduce a dynamic sparsification procedure for attention matrices applied during training, and demonstrate that it becomes significantly effective in noisy environments, where the correlation between the target variable and the optimal predictor is on the order of a few percent. Analysis of the learned attention patterns reveals interpretable structure and suggests connections to sparsity-inducing regularization in classical regression, providing insight into why these models generalize effectively under noise.

Time-to-Event Transformer to Capture Timing Attention of Events in EHR Time Series

Automatically discovering personalized sequential events from large-scale time-series data is crucial for enabling precision medicine in clinical research, yet it remains a formidable challenge even for contemporary AI models. For example, while transformers capture rich associations, they are mostly agnostic to event timing and ordering, thereby bypassing potential causal reasoning. Intuitively, we need a method capable of evaluating the "degree of alignment" among patient-specific trajectories and identifying their shared patterns, i.e., the significant events in a consistent sequence. This necessitates treating timing as a true \emph{computable} dimension, allowing models to assign ``relative timestamps'' to candidate events beyond their observed physical times. In this work, we introduce LITT, a novel Timing-Transformer architecture that enables temporary alignment of sequential events on a virtual ``relative timeline'', thereby enabling \emph{event-timing-focused attention} and personalized interpretations of clinical trajectories. Its interpretability and effectiveness are validated on real-world longitudinal EHR data from 3,276 breast cancer patients to predict the onset timing of cardiotoxicity-induced heart disease. Furthermore, LITT outperforms both the benchmark and state-of-the-art survival analysis methods on public datasets, positioning it as a significant step forward for precision medicine in clinical AI.