MATE: LLM-Powered Multi-Agent Translation Environment for Accessibility Applications

Accessibility remains a critical concern in today's society, as many technologies are not developed to support the full range of user needs. Existing multi-agent systems (MAS) often cannot provide comprehensive assistance for users in need due to the lack of customization stemming from closed-source designs. Consequently, individuals with disabilities frequently encounter significant barriers when attempting to interact with digital environments. We introduce MATE, a multimodal accessibility MAS, which performs the modality conversions based on the user's needs. The system is useful for assisting people with disabilities by ensuring that data will be converted to an understandable format. For instance, if the user cannot see well and receives an image, the system converts this image to its audio description. MATE can be applied to a wide range of domains, industries, and areas, such as healthcare, and can become a useful assistant for various groups of users. The system supports multiple types of models, ranging from LLM API calling to using custom machine learning (ML) classifiers. This flexibility ensures that the system can be adapted to various needs and is compatible with a wide variety of hardware. Since the system is expected to run locally, it ensures the privacy and security of sensitive information. In addition, the framework can be effectively integrated with institutional technologies (e.g., digital healthcare service) for real-time user assistance. Furthermore, we introduce ModCon-Task-Identifier, a model that is capable of extracting the precise modality conversion task from the user input. Numerous experiments show that ModCon-Task-Identifier consistently outperforms other LLMs and statistical models on our custom data. Our code and data are publicly available at https://github.com/AlgazinovAleksandr/Multi-Agent-MATE.

Enhancing AI Face Realism: Cost-Efficient Quality Improvement in Distilled Diffusion Models with a Fully Synthetic Dataset

This study presents a novel approach to enhance the cost-to-quality ratio of image generation with diffusion models. We hypothesize that differences between distilled (e.g. FLUX.1-schnell) and baseline (e.g. FLUX.1-dev) models are consistent and, therefore, learnable within a specialized domain, like portrait generation. We generate a synthetic paired dataset and train a fast image-to-image translation head. Using two sets of low- and high-quality synthetic images, our model is trained to refine the output of a distilled generator (e.g., FLUX.1-schnell) to a level comparable to a baseline model like FLUX.1-dev, which is more computationally intensive. Our results show that the pipeline, which combines a distilled version of a large generative model with our enhancement layer, delivers similar photorealistic portraits to the baseline version with up to an 82% decrease in computational cost compared to FLUX.1-dev. This study demonstrates the potential for improving the efficiency of AI solutions involving large-scale image generation.

Replace in Translation: Boost Concept Alignment in Counterfactual Text-to-Image

Text-to-Image (T2I) has been prevalent in recent years, with most common condition tasks having been optimized nicely. Besides, counterfactual Text-to-Image is obstructing us from a more versatile AIGC experience. For those scenes that are impossible to happen in real world and anti-physics, we should spare no efforts in increasing the factual feel, which means synthesizing images that people think very likely to be happening, and concept alignment, which means all the required objects should be in the same frame. In this paper, we focus on concept alignment. As controllable T2I models have achieved satisfactory performance for real applications, we utilize this technology to replace the objects in a synthesized image in latent space step-by-step to change the image from a common scene to a counterfactual scene to meet the prompt. We propose a strategy to instruct this replacing process, which is called as Explicit Logical Narrative Prompt (ELNP), by using the newly SoTA language model DeepSeek to generate the instructions. Furthermore, to evaluate models' performance in counterfactual T2I, we design a metric to calculate how many required concepts in the prompt can be covered averagely in the synthesized images. The extensive experiments and qualitative comparisons demonstrate that our strategy can boost the concept alignment in counterfactual T2I.

GAN-based synthetic FDG PET images from T1 brain MRI can serve to improve performance of deep unsupervised anomaly detection models

Background and Objective. Research in the cross-modal medical image translation domain has been very productive over the past few years in tackling the scarce availability of large curated multimodality datasets with the promising performance of GAN-based architectures. However, only a few of these studies assessed task-based related performance of these synthetic data, especially for the training of deep models. Method. We design and compare different GAN-based frameworks for generating synthetic brain [18F]fluorodeoxyglucose (FDG) PET images from T1 weighted MRI data. We first perform standard qualitative and quantitative visual quality evaluation. Then, we explore further impact of using these fake PET data in the training of a deep unsupervised anomaly detection (UAD) model designed to detect subtle epilepsy lesions in T1 MRI and FDG PET images. We introduce novel diagnostic task-oriented quality metrics of the synthetic FDG PET data tailored to our unsupervised detection task, then use these fake data to train a use case UAD model combining a deep representation learning based on siamese autoencoders with a OC-SVM density support estimation model. This model is trained on normal subjects only and allows the detection of any variation from the pattern of the normal population. We compare the detection performance of models trained on 35 paired real MR T1 of normal subjects paired either on 35 true PET images or on 35 synthetic PET images generated from the best performing generative models. Performance analysis is conducted on 17 exams of epilepsy patients undergoing surgery. Results. The best performing GAN-based models allow generating realistic fake PET images of control subject with SSIM and PSNR values around 0.9 and 23.8, respectively and in distribution (ID) with regard to the true control dataset. The best UAD model trained on these synthetic normative PET data allows reaching 74% sensitivity. Conclusion. Our results confirm that GAN-based models are the best suited for MR T1 to FDG PET translation, outperforming transformer or diffusion models. We also demonstrate the diagnostic value of these synthetic data for the training of UAD models and evaluation on clinical exams of epilepsy patients. Our code and the normative image dataset are available.

Translation-Equivariance of Normalization Layers and Aliasing in Convolutional Neural Networks

The design of convolutional neural architectures that are exactly equivariant to continuous translations is an active field of research. It promises to benefit scientific computing, notably by making existing imaging systems more physically accurate. Most efforts focus on the design of downsampling/pooling layers, upsampling layers and activation functions, but little attention is dedicated to normalization layers. In this work, we present a novel theoretical framework for understanding the equivariance of normalization layers to discrete shifts and continuous translations. We also determine necessary and sufficient conditions for normalization layers to be equivariant in terms of the dimensions they operate on. Using real feature maps from ResNet-18 and ImageNet, we test those theoretical results empirically and find that they are consistent with our predictions.

Q-space Guided Collaborative Attention Translation Network for Flexible Diffusion-Weighted Images Synthesis

This study, we propose a novel Q-space Guided Collaborative Attention Translation Networks (Q-CATN) for multi-shell, high-angular resolution DWI (MS-HARDI) synthesis from flexible q-space sampling, leveraging the commonly acquired structural MRI data. Q-CATN employs a collaborative attention mechanism to effectively extract complementary information from multiple modalities and dynamically adjust its internal representations based on flexible q-space information, eliminating the need for fixed sampling schemes. Additionally, we introduce a range of task-specific constraints to preserve anatomical fidelity in DWI, enabling Q-CATN to accurately learn the intrinsic relationships between directional DWI signal distributions and q-space. Extensive experiments on the Human Connectome Project (HCP) dataset demonstrate that Q-CATN outperforms existing methods, including 1D-qDL, 2D-qDL, MESC-SD, and QGAN, in estimating parameter maps and fiber tracts both quantitatively and qualitatively, while preserving fine-grained details. Notably, its ability to accommodate flexible q-space sampling highlights its potential as a promising toolkit for clinical and research applications. Our code is available at https://github.com/Idea89560041/Q-CATN.

PhytoSynth: Leveraging Multi-modal Generative Models for Crop Disease Data Generation with Novel Benchmarking and Prompt Engineering Approach

Collecting large-scale crop disease images in the field is labor-intensive and time-consuming. Generative models (GMs) offer an alternative by creating synthetic samples that resemble real-world images. However, existing research primarily relies on Generative Adversarial Networks (GANs)-based image-to-image translation and lack a comprehensive analysis of computational requirements in agriculture. Therefore, this research explores a multi-modal text-to-image approach for generating synthetic crop disease images and is the first to provide computational benchmarking in this context. We trained three Stable Diffusion (SD) variants-SDXL, SD3.5M (medium), and SD3.5L (large)-and fine-tuned them using Dreambooth and Low-Rank Adaptation (LoRA) fine-tuning techniques to enhance generalization. SD3.5M outperformed the others, with an average memory usage of 18 GB, power consumption of 180 W, and total energy use of 1.02 kWh/500 images (0.002 kWh per image) during inference task. Our results demonstrate SD3.5M's ability to generate 500 synthetic images from just 36 in-field samples in 1.5 hours. We recommend SD3.5M for efficient crop disease data generation.

Enhancing Synthetic CT from CBCT via Multimodal Fusion: A Study on the Impact of CBCT Quality and Alignment

Cone-Beam Computed Tomography (CBCT) is widely used for real-time intraoperative imaging due to its low radiation dose and high acquisition speed. However, despite its high resolution, CBCT suffers from significant artifacts and thereby lower visual quality, compared to conventional Computed Tomography (CT). A recent approach to mitigate these artifacts is synthetic CT (sCT) generation, translating CBCT volumes into the CT domain. In this work, we enhance sCT generation through multimodal learning, integrating intraoperative CBCT with preoperative CT. Beyond validation on two real-world datasets, we use a versatile synthetic dataset, to analyze how CBCT-CT alignment and CBCT quality affect sCT quality. The results demonstrate that multimodal sCT consistently outperform unimodal baselines, with the most significant gains observed in well-aligned, low-quality CBCT-CT cases. Finally, we demonstrate that these findings are highly reproducible in real-world clinical datasets.

The Role of AI in Early Detection of Life-Threatening Diseases: A Retinal Imaging Perspective

Retinal imaging has emerged as a powerful, non-invasive modality for detecting and quantifying biomarkers of systemic diseases-ranging from diabetes and hypertension to Alzheimer's disease and cardiovascular disorders but current insights remain dispersed across platforms and specialties. Recent technological advances in optical coherence tomography (OCT/OCTA) and adaptive optics (AO) now deliver ultra-high-resolution scans (down to 5 {\mu}m ) with superior contrast and spatial integration, allowing early identification of microvascular abnormalities and neurodegenerative changes. At the same time, AI-driven and machine learning (ML) algorithms have revolutionized the analysis of large-scale retinal datasets, increasing sensitivity and specificity; for example, deep learning models achieve > 90 \% sensitivity for diabetic retinopathy and AUC = 0.89 for the prediction of cardiovascular risk from fundus photographs. The proliferation of mobile health technologies and telemedicine platforms further extends access, reduces costs, and facilitates community-based screening and longitudinal monitoring. Despite these breakthroughs, translation into routine practice is hindered by heterogeneous imaging protocols, limited external validation of AI models, and integration challenges within clinical workflows. In this review, we systematically synthesize the latest OCT/OCT and AO developments, AI/ML approaches, and mHealth/Tele-ophthalmology initiatives and quantify their diagnostic performance across disease domains. Finally, we propose a roadmap for multicenter protocol standardization, prospective validation trials, and seamless incorporation of retinal screening into primary and specialty care pathways-paving the way for precision prevention, early intervention, and ongoing treatment of life-threatening systemic diseases.

RoboSwap: A GAN-driven Video Diffusion Framework For Unsupervised Robot Arm Swapping

Recent advancements in generative models have revolutionized video synthesis and editing. However, the scarcity of diverse, high-quality datasets continues to hinder video-conditioned robotic learning, limiting cross-platform generalization. In this work, we address the challenge of swapping a robotic arm in one video with another: a key step for crossembodiment learning. Unlike previous methods that depend on paired video demonstrations in the same environmental settings, our proposed framework, RoboSwap, operates on unpaired data from diverse environments, alleviating the data collection needs. RoboSwap introduces a novel video editing pipeline integrating both GANs and diffusion models, combining their isolated advantages. Specifically, we segment robotic arms from their backgrounds and train an unpaired GAN model to translate one robotic arm to another. The translated arm is blended with the original video background and refined with a diffusion model to enhance coherence, motion realism and object interaction. The GAN and diffusion stages are trained independently. Our experiments demonstrate that RoboSwap outperforms state-of-the-art video and image editing models on three benchmarks in terms of both structural coherence and motion consistency, thereby offering a robust solution for generating reliable, cross-embodiment data in robotic learning.