Ontology-Guided Diffusion for Zero-Shot Visual Sim2Real Transfer

Bridging the simulation-to-reality (sim2real) gap remains challenging as labelled real-world data is scarce. Existing diffusion-based approaches rely on unstructured prompts or statistical alignment, which do not capture the structured factors that make images look real. We introduce Ontology- Guided Diffusion (OGD), a neuro-symbolic zero-shot sim2real image translation framework that represents realism as structured knowledge. OGD decomposes realism into an ontology of interpretable traits -- such as lighting and material properties -- and encodes their relationships in a knowledge graph. From a synthetic image, OGD infers trait activations and uses a graph neural network to produce a global embedding. In parallel, a symbolic planner uses the ontology traits to compute a consistent sequence of visual edits needed to narrow the realism gap. The graph embedding conditions a pretrained instruction-guided diffusion model via cross-attention, while the planned edits are converted into a structured instruction prompt. Across benchmarks, our graph-based embeddings better distinguish real from synthetic imagery than baselines, and OGD outperforms state-of-the-art diffusion methods in sim2real image translations. Overall, OGD shows that explicitly encoding realism structure enables interpretable, data-efficient, and generalisable zero-shot sim2real transfer.

GSMem: 3D Gaussian Splatting as Persistent Spatial Memory for Zero-Shot Embodied Exploration and Reasoning

Effective embodied exploration requires agents to accumulate and retain spatial knowledge over time. However, existing scene representations, such as discrete scene graphs or static view-based snapshots, lack \textit{post-hoc re-observability}. If an initial observation misses a target, the resulting memory omission is often irrecoverable. To bridge this gap, we propose \textbf{GSMem}, a zero-shot embodied exploration and reasoning framework built upon 3D Gaussian Splatting (3DGS). By explicitly parameterizing continuous geometry and dense appearance, 3DGS serves as a persistent spatial memory that endows the agent with \textit{Spatial Recollection}: the ability to render photorealistic novel views from optimal, previously unoccupied viewpoints. To operationalize this, GSMem employs a retrieval mechanism that simultaneously leverages parallel object-level scene graphs and semantic-level language fields. This complementary design robustly localizes target regions, enabling the agent to ``hallucinate'' optimal views for high-fidelity Vision-Language Model (VLM) reasoning. Furthermore, we introduce a hybrid exploration strategy that combines VLM-driven semantic scoring with a 3DGS-based coverage objective, balancing task-aware exploration with geometric coverage. Extensive experiments on embodied question answering and lifelong navigation demonstrate the robustness and effectiveness of our framework

GEAR: Geography-knowledge Enhanced Analog Recognition Framework in Extreme Environments

The Mariana Trench and the Qinghai-Tibet Plateau exhibit significant similarities in geological origins and microbial metabolic functions. Given that deep-sea biological sampling faces prohibitive costs, recognizing structurally homologous terrestrial analogs of the Mariana Trench on the Qinghai-Tibet Plateau is of great significance. Yet, no existing model adequately addresses cross-domain topographic similarity retrieval, either neglecting geographical knowledge or sacrificing computational efficiency. To address these challenges, we present \underline{\textbf{G}}eography-knowledge \underline{\textbf{E}}nhanced \underline{\textbf{A}}nalog \underline{\textbf{R}}ecognition (\textbf{GEAR}) Framework, a three-stage pipeline designed to efficiently retrieve analogs from 2.5 million square kilometers of the Qinghai-Tibet Plateau: (1) Skeleton guided Screening and Clipping: Recognition of candidate valleys and initial screening based on size and linear morphological criteria. (2) Physics aware Filtering: The Topographic Waveform Comparator (TWC) and Morphological Texture Module (MTM) evaluate the waveform and texture and filter out inconsistent candidate valleys. (3) Graph based Fine Recognition: We design a \underline{\textbf{M}}orphology-integrated \underline{\textbf{S}}iamese \underline{\textbf{G}}raph \underline{\textbf{N}}etwork (\textbf{MSG-Net}) based on geomorphological metrics. Correspondingly, we release an expert-annotated topographic similarity dataset targeting tectonic collision zones. Experiments demonstrate the effectiveness of every stage. Besides, MSG-Net achieved an F1-Score 1.38 percentage points higher than the SOTA baseline. Using features extracted by MSG-Net, we discovered a significant correlation with biological data, providing evidence for future biological analysis.

HypeMed: Enhancing Medication Recommendations with Hypergraph-Based Patient Relationships

Medication recommendations aim to generate safe and effective medication sets from health records. However, accurately recommending medications hinges on inferring a patient's latent clinical condition from sparse and noisy observations, which requires both (i) preserving the visit-level combinatorial semantics of co-occurring entities and (ii) leveraging informative historical references through effective, visit-conditioned retrieval. Most existing methods fall short in one of both aspects: graph-based modeling often fragments higher-order intra-visit patterns into pairwise relations, while inter-visit augmentation methods commonly exhibit an imbalance between learning a globally stable representation space and performing dynamic retrieval within it. To address these limitations, this paper proposes HypeMed, a two-stage hypergraph-based framework unifying intra-visit coherence modeling and inter-visit augmentation. HypeMed consists of two core modules: MedRep for representation pre-training, and SimMR for similarity-enhanced recommendation. In the first stage, MedRep encodes clinical visits as hyperedges via knowledge-aware contrastive pre-training, creating a globally consistent, retrieval-friendly embedding space. In the second stage, SimMR performs dynamic retrieval within this space, fusing retrieved references with the patient's longitudinal data to refine medication prediction. Evaluation on real-world benchmarks shows that HypeMed outperforms state-of-the-art baselines in both recommendation precision and DDI reduction, simultaneously enhancing the effectiveness and safety of clinical decision support.

Are a Thousand Words Better Than a Single Picture? Beyond Images -- A Framework for Multi-Modal Knowledge Graph Dataset Enrichment

Multi-Modal Knowledge Graphs (MMKGs) benefit from visual information, yet large-scale image collection is hard to curate and often excludes ambiguous but relevant visuals (e.g., logos, symbols, abstract scenes). We present Beyond Images, an automatic data-centric enrichment pipeline with optional human auditing. This pipeline operates in three stages: (1) large-scale retrieval of additional entity-related images, (2) conversion of all visual inputs into textual descriptions to ensure that ambiguous images contribute usable semantics rather than noise, and (3) fusion of multi-source descriptions using a large language model (LLM) to generate concise, entity-aligned summaries. These summaries replace or augment the text modality in standard MMKG models without changing their architectures or loss functions. Across three public MMKG datasets and multiple baseline models, we observe consistent gains (up to 7% Hits@1 overall). Furthermore, on a challenging subset of entities with visually ambiguous logos and symbols, converting images into text yields large improvements (201.35% MRR and 333.33% Hits@1). Additionally, we release a lightweight Text-Image Consistency Check Interface for optional targeted audits, improving description quality and dataset reliability. Our results show that scaling image coverage and converting ambiguous visuals into text is a practical path to stronger MMKG completion. Code, datasets, and supplementary materials are available at https://github.com/pengyu-zhang/Beyond-Images.

Open Biomedical Knowledge Graphs at Scale: Construction, Federation, and AI Agent Access with Samyama Graph Database

Biomedical knowledge is fragmented across siloed databases -- Reactome for pathways, STRING for protein interactions, ClinicalTrials.gov for study registries, DrugBank for drug vocabularies, DGIdb for drug-gene interactions, SIDER for side effects. We present three open-source biomedical knowledge graphs -- Pathways KG (118,686 nodes, 834,785 edges from 5 sources), Clinical Trials KG (7,774,446 nodes, 26,973,997 edges from 5 sources), and Drug Interactions KG (32,726 nodes, 191,970 edges from 3 sources) -- built on Samyama, a high-performance graph database written in Rust. Our contributions are threefold. First, we describe a reproducible ETL pattern for constructing large-scale KGs from heterogeneous public data sources, with cross-source deduplication, batch loading (Python Cypher and Rust native loaders), and portable snapshot export. Second, we demonstrate cross-KG federation: loading all three snapshots into a single graph tenant enables property-based joins across datasets. Third, we introduce schema-driven MCP server generation for LLM agent access, evaluated on a new BiomedQA benchmark (40 pharmacology questions): domain-specific MCP tools achieve 98% accuracy vs. 0% for text-to-Cypher and 75% for standalone GPT-4o. All data sources are open-license. The combined federated graph (7.9M nodes, 28M edges) loads in approximately 3 minutes on commodity cloud hardware, and cross-KG queries complete in 80ms-4s.

Training-Only Heterogeneous Image-Patch-Text Graph Supervision for Advancing Few-Shot Learning Adapters

Recent adapter-based CLIP tuning (e.g., Tip-Adapter) is a strong few-shot learner, achieving efficiency by caching support features for fast prototype matching. However, these methods rely on global uni-modal feature vectors, overlooking fine-grained patch relations and their structural alignment with class text. To bridge this gap without incurring inference costs, we introduce a novel asymmetric training-only framework. Instead of altering the lightweight adapter, we construct a high-capacity auxiliary Heterogeneous Graph Teacher that operates solely during training. This teacher (i) integrates multi-scale visual patches and text prompts into a unified graph, (ii) performs deep cross-modal reasoning via a Modality-aware Graph Transformer (MGT), and (iii) applies discriminative node filtering to extract high-fidelity class features. Crucially, we employ a cache-aware dual-objective strategy to supervise this relational knowledge directly into the Tip-Adapter's key-value cache, effectively upgrading the prototypes while the graph teacher is discarded at test time. Thus, inference remains identical to Tip-Adapter with zero extra latency or memory. Across standard 1-16-shot benchmarks, our method consistently establishes a new state-of-the-art. Ablations confirm that the auxiliary graph supervision, text-guided reasoning, and node filtering are the essential ingredients for robust few-shot adaptation. Code is available at https://github.com/MR-Sherif/TOGA.git.

SIA: A Synthesize-Inject-Align Framework for Knowledge-Grounded and Secure E-commerce Search LLMs with Industrial Deployment

Large language models offer transformative potential for e-commerce search by enabling intent-aware recommendations. However, their industrial deployment is hindered by two critical challenges: (1) knowledge hallucination due to insufficient encoding of dynamic, fine-grained product knowledge, and (2) security vulnerabilities under jailbreak attacks that threaten compliance. To address these issues, we propose SI--a Synthesize-Inject-Align framework for building knowledgeable and secure e-commerce search LLMs. Our approach first synthesizes high-quality natural language corpus by combining structured knowledge graphs with unstructured behavioral logs, augmented with reasoning chains and safety-aware data.We then introduce a parameter-efficient pre-training strategy based on Depth Up-Scaling to inject domain knowledge while preserving general capabilities. Finally, a dual-path alignment method via multi-task instruction tuning and adversarial training strengthens both task performance and safety robustness. The framework has been deployed at JD.com, China's largest self-operated e-commerce platform, where A/B tests across five core search scenarios demonstrate significant improvements in key business metrics, validating its industrial effectiveness and scalability.

Modeling Overlapped Speech with Shuffles

We propose to model parallel streams of data, such as overlapped speech, using shuffles. Specifically, this paper shows how the shuffle product and partial order finite-state automata (FSAs) can be used for alignment and speaker-attributed transcription of overlapped speech. We train using the total score on these FSAs as a loss function, marginalizing over all possible serializations of overlapping sequences at subword, word, and phrase levels. To reduce graph size, we impose temporal constraints by constructing partial order FSAs. We address speaker attribution by modeling (token, speaker) tuples directly. Viterbi alignment through the shuffle product FSA directly enables one-pass alignment. We evaluate performance on synthetic LibriSpeech overlaps. To our knowledge, this is the first algorithm that enables single-pass alignment of multi-talker recordings. All algorithms are implemented using k2 / Icefall.

Knowledge Graph Extraction from Biomedical Literature for Alkaptonuria Rare Disease

Alkaptonuria (AKU) is an ultra-rare autosomal recessive metabolic disorder caused by mutations in the HGD (Homogentisate 1,2-Dioxygenase) gene, leading to a pathological accumulation of homogentisic acid (HGA) in body fluids and tissues. This leads to systemic manifestations, including premature spondyloarthropathy, renal and prostatic stones, and cardiovascular complications. Being ultra-rare, the amount of data related to the disease is limited, both in terms of clinical data and literature. Knowledge graphs (KGs) can help connect the limited knowledge about the disease (basic mechanisms, manifestations and existing therapies) with other knowledge; however, AKU is frequently underrepresented or entirely absent in existing biomedical KGs. In this work, we apply a text-mining methodology based on PubTator3 for large-scale extraction of biomedical relations. We construct two KGs of different sizes, validate them using existing biochemical knowledge and use them to extract genes, diseases and therapies possibly related to AKU. This computational framework reveals the systemic interactions of the disease, its comorbidities, and potential therapeutic targets, demonstrating the efficacy of our approach in analyzing rare metabolic disorders.