A Manifold Proximal Linear Method for Sparse Spectral Clustering with Application to Single-Cell RNA Sequencing Data Analysis

Spectral clustering is one of the fundamental unsupervised learning methods widely used in data analysis. Sparse spectral clustering (SSC) imposes sparsity to the spectral clustering and it improves the interpretability of the model. This paper considers a widely adopted model for SSC, which can be formulated as an optimization problem over the Stiefel manifold with nonsmooth and nonconvex objective. Such an optimization problem is very challenging to solve. Existing methods usually solve its convex relaxation or need to smooth its nonsmooth part using certain smoothing techniques. In this paper, we propose a manifold proximal linear method (ManPL) that solves the original SSC formulation. We also extend the algorithm to solve the multiple-kernel SSC problems, for which an alternating ManPL algorithm is proposed. Convergence and iteration complexity results of the proposed methods are established. We demonstrate the advantage of our proposed methods over existing methods via the single-cell RNA sequencing data analysis.

Zeroth-Order Algorithms for Nonconvex Minimax Problems with Improved Complexities

In this paper, we study zeroth-order algorithms for minimax optimization problems that are nonconvex in one variable and strongly-concave in the other variable. Such minimax optimization problems have attracted significant attention lately due to their applications in modern machine learning tasks. We first design and analyze the Zeroth-Order Gradient Descent Ascent (\texttt{ZO-GDA}) algorithm, and provide improved results compared to existing works, in terms of oracle complexity. Next, we propose the Zeroth-Order Gradient Descent Multi-Step Ascent (\texttt{ZO-GDMSA}) algorithm that significantly improves the oracle complexity of \texttt{ZO-GDA}. We also provide stochastic version of \texttt{ZO-GDA} and \texttt{ZO-GDMSA} to handle stochastic nonconvex minimax problems, and provide oracle complexity results.

Nonconvex Stochastic Nested Optimization via Stochastic ADMM

We consider the stochastic nested composition optimization problem where the objective is a composition of two expected-value functions. We proposed the stochastic ADMM to solve this complicated objective. In order to find an $\epsilon$ stationary point where the expected norm of the subgradient of corresponding augmented Lagrangian is smaller than $\epsilon$, the total sample complexity of our method is $\mathcal{O}(\epsilon^{-3})$ for the online case and $\mathcal{O} \Bigl((2N_1 + N_2) + (2N_1 + N_2)^{1/2}\epsilon^{-2}\Bigr)$ for the finite sum case. The computational complexity is consistent with proximal version proposed in \cite{zhang2019multi}, but our algorithm can solve more general problem when the proximal mapping of the penalty is not easy to compute.