From Sports to Safety: Benchmarking Proactive Risk Inference in MLLMs

Timely anticipation of physical hazards is essential for real-world safety, yet existing MLLM evaluations focus on harmful content or general risks, leaving proactive physical hazard prediction underexplored. Sports provide a well-suited testbed: accident causes span diverse injury dimensions and pre-accident spatiotemporal cues draw on reasoning capabilities shared with broader safety domains such as autonomous driving and fall detection. We introduce SPRINT (Sports Proactive Risk INference Testbed), a benchmark of 2,888 real-world sports videos (2,440 accident, 448 safe controls) spanning 14 sports and 3 environmental settings. Accident videos feature fine-grained annotations of early hazard cues, accident timing, and hierarchical causes; safe videos are manually verified as accident-free and serve to diagnose prompt-induced false alarms. Evaluating state-of-the-art MLLMs under diverse prompts and temporal windows reveals a sharp gap between hazard sensitivity and understanding: the best model exceeds 95% in signaling hazards yet falls below 50% in identifying their causes. Diagnostic experiments further show that explicit danger queries trigger severe false alarms even on hazard-free videos. These findings indicate that current MLLMs exhibit only superficial proactive safety, lacking stable, cause-grounded early warning, and underscore the need for reliable proactive safety in dynamic physical environments. Data and code will be open-sourced upon acceptance.

AI for Social Good: An Investigation of the Causal Relationship Between Environmental Regulations and Their Effects on Air Pollution in London, UK

Air pollution regulation is central to urban public health governance, but estimating its effects is difficult because policies are implemented non-randomly and pollution trajectories are shaped by meteorology, socioeconomic change, temporal trends, and overlapping interventions. This study develops an uncertainty-aware Bayesian deep learning framework to estimate the aggregate effect of air pollution regulations on PM$_{2.5}$ concentrations in London from 2010 to 2020. The framework integrates daily PM$_{2.5}$ observations from Inner London monitoring stations, meteorological covariates, annual socioeconomic indicators, month-of-year and day-of-week indicators, and daily regulation status data for 32 policy measures. A Bayesian LSTM captures temporal dependencies in environmental and socioeconomic covariates, Bayesian embedding layers represent temporal and regulation status inputs, and a regulation status prediction branch supports propensity score-based adjustment for non-random policy implementation. Regulatory effects are estimated by comparing observed PM$_{2.5}$ concentrations with counterfactual predictions under a hypothetical no-regulation scenario, with uncertainty summarized across repeated Bayesian training runs and bootstrap resampling. Results show that London's regulations were associated with an average PM$_{2.5}$ reduction of 1.88 $μ$g/m$^3$, a relative reduction of 12.35%, with a 95% confidence interval of 1.64-2.12 $μ$g/m$^3$. Estimated effects were limited before 2013, became clearer from 2013 to 2017, and were strongest in 2018 and 2019. The findings suggest that sustained and cumulative regulatory interventions contributed to measurable improvements in London's air quality. This study demonstrates how uncertainty-aware causal AI can support environmental accountability, public health protection, and evidence-based governance for environmental decision-making.

SmartDirector: Keyframe-Conditioned Cinematic Video Generation with Narrative Pacing Control

The narrative quality of a video fundamentally determines its perceptual value. Although existing video generation methods can produce visually appealing content, they predominantly rely on sparse conditioning signals such as text prompts or first/last frames, which limits precise control over narrative structure and temporal pacing. In this paper, we propose SmartDirector, a framework that enhances the narrative capacity of video generation models through multiple keyframes. SmartDirector supports flexible generation scenarios including single-shot generation, multi-shot narrative synthesis, and video extension. The framework operates in two stages: Director-Gen generates a low-resolution video conditioned on the provided keyframes, and Director-SR refines the output by exploiting high-resolution keyframes as semantic anchors to recover fine-grained details. To enable robust multi-keyframe training, we construct a data pipeline that curates single-shot and multi-shot sequences from movies. Extensive experiments demonstrate that SmartDirector substantially outperforms existing state-of-the-art approaches. We will release the code to facilitate further research.

Do We Need Distinct Representations for Every Speech Token? Unveiling and Exploiting Redundancy in Large Speech Language Models

Large Speech Language Models (LSLMs) typically operate at high token rates (tokens/s) to ensure acoustic fidelity, yet this results in sequence lengths that far exceed the underlying semantic content, incurring prohibitive inference costs. In this paper, we empirically revisit the necessity of such granular token-level processing. Through layer-wise oracle interventions, we unveil a structured redundancy hierarchy: while shallow layers encode essential acoustic details, deep layers exhibit extreme redundancy, allowing for aggressive compression. Motivated by these findings, we introduce Affinity Pooling, a training-free, similarity-based token merging mechanism. By strategically applying this method at both input and deep layers, we effectively compress speech representations without compromising semantic information. Extensive evaluations across three tasks demonstrate that our approach reduces prefilling FLOPs by 27.48\% while maintaining competitive accuracy. Practical deployment further confirms significant efficiency gains, yielding up to $\sim$1.7$\times$ memory savings and $\sim$1.1$\times$ faster time-to-first-token on long utterances. Our results challenge the necessity of fully distinct token representations, providing new perspectives on LSLM efficiency.

Label Noise Cleaning for Supervised Classification via Bernoulli Random Sampling

Label noise - incorrect labels assigned to observations - can substantially degrade the performance of supervised classifiers. This paper proposes a label noise cleaning method based on Bernoulli random sampling. We show that the mean label noise levels of subsets generated by Bernoulli random sampling containing a given observation are identically distributed for all clean observations, and identically distributed, with a different distribution, for all noisy observations. Although the mean label noise levels are not independent across observations, by introducing an independent coupling we further prove that they converge to a mixture of two well-separated distributions corresponding to clean and noisy observations. By establishing a linear model between cross-validated classification errors and label noise levels, we are able to approximate this mixture distribution and thereby separate clean and noisy observations without any prior label information. The proposed method is classifier-agnostic, theoretically justified, and demonstrates strong performance on both simulated and real datasets.

EagleVision: A Dual-Stage Framework with BEV-grounding-based Chain-of-Thought for Spatial Intelligence

Recent spatial intelligence approaches typically attach 3D cues to 2D reasoning pipelines or couple MLLMs with black-box reconstruction modules, leading to weak spatial consistency, limited viewpoint diversity, and evidence chains that cannot be traced back to supporting views. Frameworks for "thinking with images" (e.g., ChatGPT-o3 and DeepEyes) show that stepwise multimodal reasoning can emerge by interleaving hypothesis formation with active acquisition of visual evidence, but they do not address three key challenges in spatial Chain-of-Thought (CoT): building global space perception under strict token budgets, explicitly associating 3D hypotheses with video frames for verification, and designing spatially grounded rewards for reinforcement learning. To address these issues, we present EagleVision, a dual-stage framework for progressive spatial cognition through macro perception and micro verification. In the macro perception stage, EagleVision employs a semantics-perspective-fusion determinantal point process (SPF-DPP) to select a compact set of geometry- and semantics-aware keyframes from long videos under a fixed token budget. In the micro verification stage, we formalize spatial CoT as BEV-grounded pose querying: the agent iteratively predicts poses on a BEV plane, retrieves the nearest real frames, and is trained purely by reinforcement learning with a spatial grounding reward that scores the consistency between predicted poses and observed views. On VSI-Bench, EagleVision achieves state-of-the-art performance among open-source vision-language models, demonstrating strong and generalizable spatial understanding.

MS-BART: Unified Modeling of Mass Spectra and Molecules for Structure Elucidation

Mass spectrometry (MS) plays a critical role in molecular identification, significantly advancing scientific discovery. However, structure elucidation from MS data remains challenging due to the scarcity of annotated spectra. While large-scale pretraining has proven effective in addressing data scarcity in other domains, applying this paradigm to mass spectrometry is hindered by the complexity and heterogeneity of raw spectral signals. To address this, we propose MS-BART, a unified modeling framework that maps mass spectra and molecular structures into a shared token vocabulary, enabling cross-modal learning through large-scale pretraining on reliably computed fingerprint-molecule datasets. Multi-task pretraining objectives further enhance MS-BART's generalization by jointly optimizing denoising and translation task. The pretrained model is subsequently transferred to experimental spectra through finetuning on fingerprint predictions generated with MIST, a pre-trained spectral inference model, thereby enhancing robustness to real-world spectral variability. While finetuning alleviates the distributional difference, MS-BART still suffers molecular hallucination and requires further alignment. We therefore introduce a chemical feedback mechanism that guides the model toward generating molecules closer to the reference structure. Extensive evaluations demonstrate that MS-BART achieves SOTA performance across 5/12 key metrics on MassSpecGym and NPLIB1 and is faster by one order of magnitude than competing diffusion-based methods, while comprehensive ablation studies systematically validate the model's effectiveness and robustness.

Reverse-Speech-Finder: A Neural Network Backtracking Architecture for Generating Alzheimer's Disease Speech Samples and Improving Diagnosis Performance

This study introduces Reverse-Speech-Finder (RSF), a groundbreaking neural network backtracking architecture designed to enhance Alzheimer's Disease (AD) diagnosis through speech analysis. Leveraging the power of pre-trained large language models, RSF identifies and utilizes the most probable AD-specific speech markers, addressing both the scarcity of real AD speech samples and the challenge of limited interpretability in existing models. RSF's unique approach consists of three core innovations: Firstly, it exploits the observation that speech markers most probable of predicting AD, defined as the most probable speech-markers (MPMs), must have the highest probability of activating those neurons (in the neural network) with the highest probability of predicting AD, defined as the most probable neurons (MPNs). Secondly, it utilizes a speech token representation at the input layer, allowing backtracking from MPNs to identify the most probable speech-tokens (MPTs) of AD. Lastly, it develops an innovative backtracking method to track backwards from the MPNs to the input layer, identifying the MPTs and the corresponding MPMs, and ingeniously uncovering novel speech markers for AD detection. Experimental results demonstrate RSF's superiority over traditional methods such as SHAP and Integrated Gradients, achieving a 3.5% improvement in accuracy and a 3.2% boost in F1-score. By generating speech data that encapsulates novel markers, RSF not only mitigates the limitations of real data scarcity but also significantly enhances the robustness and accuracy of AD diagnostic models. These findings underscore RSF's potential as a transformative tool in speech-based AD detection, offering new insights into AD-related linguistic deficits and paving the way for more effective non-invasive early intervention strategies.

Unravelling Causal Genetic Biomarkers of Alzheimer's Disease via Neuron to Gene-token Backtracking in Neural Architecture: A Groundbreaking Reverse-Gene-Finder Approach

Alzheimer's Disease (AD) affects over 55 million people globally, yet the key genetic contributors remain poorly understood. Leveraging recent advancements in genomic foundation models, we present the innovative Reverse-Gene-Finder technology, a ground-breaking neuron-to-gene-token backtracking approach in a neural network architecture to elucidate the novel causal genetic biomarkers driving AD onset. Reverse-Gene-Finder comprises three key innovations. Firstly, we exploit the observation that genes with the highest probability of causing AD, defined as the most causal genes (MCGs), must have the highest probability of activating those neurons with the highest probability of causing AD, defined as the most causal neurons (MCNs). Secondly, we utilize a gene token representation at the input layer to allow each gene (known or novel to AD) to be represented as a discrete and unique entity in the input space. Lastly, in contrast to the existing neural network architectures, which track neuron activations from the input layer to the output layer in a feed-forward manner, we develop an innovative backtracking method to track backwards from the MCNs to the input layer, identifying the Most Causal Tokens (MCTs) and the corresponding MCGs. Reverse-Gene-Finder is highly interpretable, generalizable, and adaptable, providing a promising avenue for application in other disease scenarios.

From Generalist to Specialist: A Survey of Large Language Models for Chemistry

Large Language Models (LLMs) have significantly transformed our daily life and established a new paradigm in natural language processing (NLP). However, the predominant pretraining of LLMs on extensive web-based texts remains insufficient for advanced scientific discovery, particularly in chemistry. The scarcity of specialized chemistry data, coupled with the complexity of multi-modal data such as 2D graph, 3D structure and spectrum, present distinct challenges. Although several studies have reviewed Pretrained Language Models (PLMs) in chemistry, there is a conspicuous absence of a systematic survey specifically focused on chemistry-oriented LLMs. In this paper, we outline methodologies for incorporating domain-specific chemistry knowledge and multi-modal information into LLMs, we also conceptualize chemistry LLMs as agents using chemistry tools and investigate their potential to accelerate scientific research. Additionally, we conclude the existing benchmarks to evaluate chemistry ability of LLMs. Finally, we critically examine the current challenges and identify promising directions for future research. Through this comprehensive survey, we aim to assist researchers in staying at the forefront of developments in chemistry LLMs and to inspire innovative applications in the field.