Abstract:Large language models (LLMs) demonstrate impressive capabilities across diverse tasks but raise concerns about privacy, copyright, and harmful materials. Existing LLM unlearning methods rarely consider the continual and high-volume nature of real-world deletion requests, which can cause utility degradation and catastrophic forgetting as requests accumulate. To address this challenge, we introduce \fit, a framework for continual unlearning that handles large numbers of deletion requests while maintaining robustness against both catastrophic forgetting and post-unlearning recovery. \fit mitigates degradation through rigorous data \underline{F}iltering, \underline{I}mportance-aware updates, and \underline{T}argeted layer attribution, enabling stable performance across long sequences of unlearning operations and achieving a favorable balance between forgetting effectiveness and utility retention. To support realistic evaluation, we present \textbf{PCH}, a benchmark covering \textbf{P}ersonal information, \textbf{C}opyright, and \textbf{H}armful content in sequential deletion scenarios, along with two symmetric metrics, Forget Degree (F.D.) and Retain Utility (R.U.), which jointly assess forgetting quality and utility preservation. Extensive experiments on four open-source LLMs with hundreds of deletion requests show that \fit achieves the strongest trade-off between F.D. and R.U., surpasses existing methods on MMLU, CommonsenseQA, and GSM8K, and remains resistant against both relearning and quantization recovery attacks.
Abstract:Although machine unlearning is essential for removing private, harmful, or copyrighted content from LLMs, current benchmarks often fail to faithfully represent the true "forgetting scope" learned by the model. We formalize two distinct unlearning granularities, domain-level and instance-level, and propose BiForget, an automated framework for synthesizing high-quality forget sets. Unlike prior work relying on external generators, BiForget exploits the target model per se to elicit data that matches its internal knowledge distribution through seed-guided and adversarial prompting. Our experiments across diverse benchmarks show that it achieves a superior balance of relevance, diversity, and efficiency. Quantitatively, in the Harry Potter domain, it improves relevance by ${\sim}20$ and diversity by ${\sim}$0.05 while halving the total data size compared to SOTAs. Ultimately, it facilitates more robust forgetting and better utility preservation, providing a more rigorous foundation for evaluating LLM unlearning.




Abstract:Purpose: To develop a fully automated deep learning system, AutoLugano, for end-to-end lymphoma classification by performing lesion segmentation, anatomical localization, and automated Lugano staging from baseline FDG-PET/CT scans. Methods: The AutoLugano system processes baseline FDG-PET/CT scans through three sequential modules:(1) Anatomy-Informed Lesion Segmentation, a 3D nnU-Net model, trained on multi-channel inputs, performs automated lesion detection (2) Atlas-based Anatomical Localization, which leverages the TotalSegmentator toolkit to map segmented lesions to 21 predefined lymph node regions using deterministic anatomical rules; and (3) Automated Lugano Staging, where the spatial distribution of involved regions is translated into Lugano stages and therapeutic groups (Limited vs. Advanced Stage).The system was trained on the public autoPET dataset (n=1,007) and externally validated on an independent cohort of 67 patients. Performance was assessed using accuracy, sensitivity, specificity, F1-scorefor regional involvement detection and staging agreement. Results: On the external validation set, the proposed model demonstrated robust performance, achieving an overall accuracy of 88.31%, sensitivity of 74.47%, Specificity of 94.21% and an F1-score of 80.80% for regional involvement detection,outperforming baseline models. Most notably, for the critical clinical task of therapeutic stratification (Limited vs. Advanced Stage), the system achieved a high accuracy of 85.07%, with a specificity of 90.48% and a sensitivity of 82.61%.Conclusion: AutoLugano represents the first fully automated, end-to-end pipeline that translates a single baseline FDG-PET/CT scan into a complete Lugano stage. This study demonstrates its strong potential to assist in initial staging, treatment stratification, and supporting clinical decision-making.




Abstract:Unlearning in large language models (LLMs) is intended to remove the influence of specific data, yet current evaluations rely heavily on token-level metrics such as accuracy and perplexity. We show that these metrics can be misleading: models often appear to forget, but their original behavior can be rapidly restored with minimal fine-tuning, revealing that unlearning may obscure information rather than erase it. To diagnose this phenomenon, we introduce a representation-level evaluation framework using PCA-based similarity and shift, centered kernel alignment, and Fisher information. Applying this toolkit across six unlearning methods, three domains (text, code, math), and two open-source LLMs, we uncover a critical distinction between reversible and irreversible forgetting. In reversible cases, models suffer token-level collapse yet retain latent features; in irreversible cases, deeper representational damage occurs. We further provide a theoretical account linking shallow weight perturbations near output layers to misleading unlearning signals, and show that reversibility is modulated by task type and hyperparameters. Our findings reveal a fundamental gap in current evaluation practices and establish a new diagnostic foundation for trustworthy unlearning in LLMs. We provide a unified toolkit for analyzing LLM representation changes under unlearning and relearning: https://github.com/XiaoyuXU1/Representational_Analysis_Tools.git.
Abstract:Large language models (LLMs) trained over extensive corpora risk memorizing sensitive, copyrighted, or toxic content. To address this, we propose OBLIVIATE, a robust unlearning framework that removes targeted data while preserving model utility. The framework follows a structured process: extracting target tokens, building retain sets, and fine-tuning with a tailored loss function comprising three components -- masking, distillation, and world fact. Using low-rank adapters (LoRA), it ensures efficiency without compromising unlearning quality. We conduct experiments on multiple datasets, including the Harry Potter series, WMDP, and TOFU, using a comprehensive suite of metrics: forget quality (new document-level memorization score), model utility, and fluency. Results demonstrate its effectiveness in resisting membership inference attacks, minimizing the impact on retained data, and maintaining robustness across diverse scenarios.
Abstract:Despite being widely applied due to their exceptional capabilities, Large Language Models (LLMs) have been proven to be vulnerable to backdoor attacks. These attacks introduce targeted vulnerabilities into LLMs by poisoning training samples and full-parameter fine-tuning. However, this kind of backdoor attack is limited since they require significant computational resources, especially as the size of LLMs increases. Besides, parameter-efficient fine-tuning (PEFT) offers an alternative but the restricted parameter updating may impede the alignment of triggers with target labels. In this study, we first verify that backdoor attacks with PEFT may encounter challenges in achieving feasible performance. To address these issues and improve the effectiveness of backdoor attacks with PEFT, we propose a novel backdoor attack algorithm from weak to strong based on contrastive knowledge distillation (W2SAttack). Specifically, we poison small-scale language models through full-parameter fine-tuning to serve as the teacher model. The teacher model then covertly transfers the backdoor to the large-scale student model through contrastive knowledge distillation, which employs PEFT. Theoretical analysis reveals that W2SAttack has the potential to augment the effectiveness of backdoor attacks. We demonstrate the superior performance of W2SAttack on classification tasks across four language models, four backdoor attack algorithms, and two different architectures of teacher models. Experimental results indicate success rates close to 100% for backdoor attacks targeting PEFT.