PhysPose: Refining 6D Object Poses with Physical Constraints

Accurate 6D object pose estimation from images is a key problem in object-centric scene understanding, enabling applications in robotics, augmented reality, and scene reconstruction. Despite recent advances, existing methods often produce physically inconsistent pose estimates, hindering their deployment in real-world scenarios. We introduce PhysPose, a novel approach that integrates physical reasoning into pose estimation through a postprocessing optimization enforcing non-penetration and gravitational constraints. By leveraging scene geometry, PhysPose refines pose estimates to ensure physical plausibility. Our approach achieves state-of-the-art accuracy on the YCB-Video dataset from the BOP benchmark and improves over the state-of-the-art pose estimation methods on the HOPE-Video dataset. Furthermore, we demonstrate its impact in robotics by significantly improving success rates in a challenging pick-and-place task, highlighting the importance of physical consistency in real-world applications.

Large-scale Pre-training for Grounded Video Caption Generation

We propose a novel approach for captioning and object grounding in video, where the objects in the caption are grounded in the video via temporally dense bounding boxes. We introduce the following contributions. First, we present a large-scale automatic annotation method that aggregates captions grounded with bounding boxes across individual frames into temporally dense and consistent bounding box annotations. We apply this approach on the HowTo100M dataset to construct a large-scale pre-training dataset, named HowToGround1M. We also introduce a Grounded Video Caption Generation model, dubbed GROVE, and pre-train the model on HowToGround1M. Second, we introduce a new dataset, called iGround, of 3500 videos with manually annotated captions and dense spatio-temporally grounded bounding boxes. This allows us to measure progress on this challenging problem, as well as to fine-tune our model on this small-scale but high-quality data. Third, we demonstrate that our approach achieves state-of-the-art results on the proposed iGround dataset compared to a number of baselines, as well as on the VidSTG and ActivityNet-Entities datasets. We perform extensive ablations that demonstrate the importance of pre-training using our automatically annotated HowToGround1M dataset followed by fine-tuning on the manually annotated iGround dataset and validate the key technical contributions of our model.

6D Object Pose Tracking in Internet Videos for Robotic Manipulation

We seek to extract a temporally consistent 6D pose trajectory of a manipulated object from an Internet instructional video. This is a challenging set-up for current 6D pose estimation methods due to uncontrolled capturing conditions, subtle but dynamic object motions, and the fact that the exact mesh of the manipulated object is not known. To address these challenges, we present the following contributions. First, we develop a new method that estimates the 6D pose of any object in the input image without prior knowledge of the object itself. The method proceeds by (i) retrieving a CAD model similar to the depicted object from a large-scale model database, (ii) 6D aligning the retrieved CAD model with the input image, and (iii) grounding the absolute scale of the object with respect to the scene. Second, we extract smooth 6D object trajectories from Internet videos by carefully tracking the detected objects across video frames. The extracted object trajectories are then retargeted via trajectory optimization into the configuration space of a robotic manipulator. Third, we thoroughly evaluate and ablate our 6D pose estimation method on YCB-V and HOPE-Video datasets as well as a new dataset of instructional videos manually annotated with approximate 6D object trajectories. We demonstrate significant improvements over existing state-of-the-art RGB 6D pose estimation methods. Finally, we show that the 6D object motion estimated from Internet videos can be transferred to a 7-axis robotic manipulator both in a virtual simulator as well as in a real world set-up. We also successfully apply our method to egocentric videos taken from the EPIC-KITCHENS dataset, demonstrating potential for Embodied AI applications.

ShowHowTo: Generating Scene-Conditioned Step-by-Step Visual Instructions

The goal of this work is to generate step-by-step visual instructions in the form of a sequence of images, given an input image that provides the scene context and the sequence of textual instructions. This is a challenging problem as it requires generating multi-step image sequences to achieve a complex goal while being grounded in a specific environment. Part of the challenge stems from the lack of large-scale training data for this problem. The contribution of this work is thus three-fold. First, we introduce an automatic approach for collecting large step-by-step visual instruction training data from instructional videos. We apply this approach to one million videos and create a large-scale, high-quality dataset of 0.6M sequences of image-text pairs. Second, we develop and train ShowHowTo, a video diffusion model capable of generating step-by-step visual instructions consistent with the provided input image. Third, we evaluate the generated image sequences across three dimensions of accuracy (step, scene, and task) and show our model achieves state-of-the-art results on all of them. Our code, dataset, and trained models are publicly available.

Generative Timelines for Instructed Visual Assembly

The objective of this work is to manipulate visual timelines (e.g. a video) through natural language instructions, making complex timeline editing tasks accessible to non-expert or potentially even disabled users. We call this task Instructed visual assembly. This task is challenging as it requires (i) identifying relevant visual content in the input timeline as well as retrieving relevant visual content in a given input (video) collection, (ii) understanding the input natural language instruction, and (iii) performing the desired edits of the input visual timeline to produce an output timeline. To address these challenges, we propose the Timeline Assembler, a generative model trained to perform instructed visual assembly tasks. The contributions of this work are three-fold. First, we develop a large multimodal language model, which is designed to process visual content, compactly represent timelines and accurately interpret timeline editing instructions. Second, we introduce a novel method for automatically generating datasets for visual assembly tasks, enabling efficient training of our model without the need for human-labeled data. Third, we validate our approach by creating two novel datasets for image and video assembly, demonstrating that the Timeline Assembler substantially outperforms established baseline models, including the recent GPT-4o, in accurately executing complex assembly instructions across various real-world inspired scenarios.

Grounded Video Caption Generation

We propose a new task, dataset and model for grounded video caption generation. This task unifies captioning and object grounding in video, where the objects in the caption are grounded in the video via temporally consistent bounding boxes. We introduce the following contributions. First, we present a task definition and a manually annotated test dataset for this task, referred to as GROunded Video Caption Generation (GROC). Second, we introduce a large-scale automatic annotation method leveraging an existing model for grounded still image captioning together with an LLM for summarising frame-level captions into temporally consistent captions in video. Furthermore, we prompt the LLM to track by language -- classifying noun phrases from the frame-level captions into noun phrases of the video-level generated caption. We apply this approach to videos from the HowTo100M dataset, which results in a new large-scale training dataset, called HowToGround, with automatically annotated captions and spatio-temporally consistent bounding boxes with coherent natural language labels. Third, we introduce a new grounded video caption generation model, called VideoGround, and train the model on the new automatically annotated HowToGround dataset. Finally, results of our VideoGround model set the state of the art for the new task of grounded video caption generation. We perform extensive ablations and demonstrate the importance of key technical contributions of our model.

Training on test proteins improves fitness, structure, and function prediction

Data scarcity and distribution shifts often hinder the ability of machine learning models to generalize when applied to proteins and other biological data. Self-supervised pre-training on large datasets is a common method to enhance generalization. However, striving to perform well on all possible proteins can limit model's capacity to excel on any specific one, even though practitioners are often most interested in accurate predictions for the individual protein they study. To address this limitation, we propose an orthogonal approach to achieve generalization. Building on the prevalence of self-supervised pre-training, we introduce a method for self-supervised fine-tuning at test time, allowing models to adapt to the test protein of interest on the fly and without requiring any additional data. We study our test-time training (TTT) method through the lens of perplexity minimization and show that it consistently enhances generalization across different models, their scales, and datasets. Notably, our method leads to new state-of-the-art results on the standard benchmark for protein fitness prediction, improves protein structure prediction for challenging targets, and enhances function prediction accuracy.

MassSpecGym: A benchmark for the discovery and identification of molecules

The discovery and identification of molecules in biological and environmental samples is crucial for advancing biomedical and chemical sciences. Tandem mass spectrometry (MS/MS) is the leading technique for high-throughput elucidation of molecular structures. However, decoding a molecular structure from its mass spectrum is exceptionally challenging, even when performed by human experts. As a result, the vast majority of acquired MS/MS spectra remain uninterpreted, thereby limiting our understanding of the underlying (bio)chemical processes. Despite decades of progress in machine learning applications for predicting molecular structures from MS/MS spectra, the development of new methods is severely hindered by the lack of standard datasets and evaluation protocols. To address this problem, we propose MassSpecGym -- the first comprehensive benchmark for the discovery and identification of molecules from MS/MS data. Our benchmark comprises the largest publicly available collection of high-quality labeled MS/MS spectra and defines three MS/MS annotation challenges: \textit{de novo} molecular structure generation, molecule retrieval, and spectrum simulation. It includes new evaluation metrics and a generalization-demanding data split, therefore standardizing the MS/MS annotation tasks and rendering the problem accessible to the broad machine learning community. MassSpecGym is publicly available at \url{https://github.com/pluskal-lab/MassSpecGym}.

Revealing data leakage in protein interaction benchmarks

In recent years, there has been remarkable progress in machine learning for protein-protein interactions. However, prior work has predominantly focused on improving learning algorithms, with less attention paid to evaluation strategies and data preparation. Here, we demonstrate that further development of machine learning methods may be hindered by the quality of existing train-test splits. Specifically, we find that commonly used splitting strategies for protein complexes, based on protein sequence or metadata similarity, introduce major data leakage. This may result in overoptimistic evaluation of generalization, as well as unfair benchmarking of the models, biased towards assessing their overfitting capacity rather than practical utility. To overcome the data leakage, we recommend constructing data splits based on 3D structural similarity of protein-protein interfaces and suggest corresponding algorithms. We believe that addressing the data leakage problem is critical for further progress in this research area.

POP-3D: Open-Vocabulary 3D Occupancy Prediction from Images

We describe an approach to predict open-vocabulary 3D semantic voxel occupancy map from input 2D images with the objective of enabling 3D grounding, segmentation and retrieval of free-form language queries. This is a challenging problem because of the 2D-3D ambiguity and the open-vocabulary nature of the target tasks, where obtaining annotated training data in 3D is difficult. The contributions of this work are three-fold. First, we design a new model architecture for open-vocabulary 3D semantic occupancy prediction. The architecture consists of a 2D-3D encoder together with occupancy prediction and 3D-language heads. The output is a dense voxel map of 3D grounded language embeddings enabling a range of open-vocabulary tasks. Second, we develop a tri-modal self-supervised learning algorithm that leverages three modalities: (i) images, (ii) language and (iii) LiDAR point clouds, and enables training the proposed architecture using a strong pre-trained vision-language model without the need for any 3D manual language annotations. Finally, we demonstrate quantitatively the strengths of the proposed model on several open-vocabulary tasks: Zero-shot 3D semantic segmentation using existing datasets; 3D grounding and retrieval of free-form language queries, using a small dataset that we propose as an extension of nuScenes. You can find the project page here https://vobecant.github.io/POP3D.