Augmenting representations with scientific papers

Astronomers have acquired vast repositories of multimodal data, including images, spectra, and time series, complemented by decades of literature that analyzes astrophysical sources. Still, these data sources are rarely systematically integrated. This work introduces a contrastive learning framework designed to align X-ray spectra with domain knowledge extracted from scientific literature, facilitating the development of shared multimodal representations. Establishing this connection is inherently complex, as scientific texts encompass a broader and more diverse physical context than spectra. We propose a contrastive pipeline that achieves a 20% Recall@1% when retrieving texts from spectra, proving that a meaningful alignment between these modalities is not only possible but capable of accelerating the interpretation of rare or poorly understood sources. Furthermore, the resulting shared latent space effectively encodes physically significant information. By fusing spectral and textual data, we improve the estimation of 20 physical variables by 16-18% over unimodal spectral baselines. Our results indicate that a Mixture of Experts (MoE) strategy, which leverages both unimodal and shared representations, yields superior performance. Finally, outlier analysis within the multimodal latent space identifies high-priority targets for follow-up investigation, including a candidate pulsating ULX (PULX) and a gravitational lens system. Importantly, this framework can be extended to other scientific domains where aligning observational data with existing literature is possible.

PrivMedChat: End-to-End Differentially Private RLHF for Medical Dialogue Systems

Large language models are increasingly used for patient-facing medical assistance and clinical decision support, but adapting them to clinical dialogue often requires supervision derived from doctor-patient conversations that may contain sensitive information. Conventional supervised fine-tuning and reinforcement learning from human feedback (RLHF) can amplify memorization risks, enabling empirical membership inference and extraction of rare training-set content. We present PrivMedChat, an end-to-end framework for differentially private RLHF (DP-RLHF) for medical dialogue. Our design enforces differential privacy at every training stage that directly accesses dialogue-derived supervision: (i) Differential Private Stochastic Gradient Descent (DP-SGD) for medical SFT and (ii) DP-SGD for reward model learning from preference pairs. To limit additional privacy expenditure during alignment, we apply DP-SGD to the PPO actor and critic when operating on dialogue-derived prompts, while the reward model remains fixed after DP training. We also introduce an annotation-free preference construction strategy that pairs physician responses with filtered non-expert generations to produce scalable preference data without clinician labeling. Experiments on medical dialogue benchmarks show that PrivMedChat at $\varepsilon=7$ achieves the highest ROUGE-L of 0.156 among all DP models, reduces clinical hallucinations to 1.4% and harmful advice to 0.4%, and obtains the highest overall score of 2.86 in a 3-model LLM-jury evaluation, while producing membership-inference signals that are near chance (AUC 0.510-0.555). We open-source our code at https://github.com/sudip-bhujel/privmedchat.

Embedding interpretable $\ell_1$-regression into neural networks for uncovering temporal structure in cell imaging

While artificial neural networks excel in unsupervised learning of non-sparse structure, classical statistical regression techniques offer better interpretability, in particular when sparseness is enforced by $\ell_1$ regularization, enabling identification of which factors drive observed dynamics. We investigate how these two types of approaches can be optimally combined, exemplarily considering two-photon calcium imaging data where sparse autoregressive dynamics are to be extracted. We propose embedding a vector autoregressive (VAR) model as an interpretable regression technique into a convolutional autoencoder, which provides dimension reduction for tractable temporal modeling. A skip connection separately addresses non-sparse static spatial information, selectively channeling sparse structure into the $\ell_1$-regularized VAR. $\ell_1$-estimation of regression parameters is enabled by differentiating through the piecewise linear solution path. This is contrasted with approaches where the autoencoder does not adapt to the VAR model. Having an embedded statistical model also enables a testing approach for comparing temporal sequences from the same observational unit. Additionally, contribution maps visualize which spatial regions drive the learned dynamics.

BAED: a New Paradigm for Few-shot Graph Learning with Explanation in the Loop

The challenges of training and inference in few-shot environments persist in the area of graph representation learning. The quality and quantity of labels are often insufficient due to the extensive expert knowledge required to annotate graph data. In this context, Few-Shot Graph Learning (FSGL) approaches have been developed over the years. Through sophisticated neural architectures and customized training pipelines, these approaches enhance model adaptability to new label distributions. However, compromises in \textcolor{black}{the model's} robustness and interpretability can result in overfitting to noise in labeled data and degraded performance. This paper introduces the first explanation-in-the-loop framework for the FSGL problem, called BAED. We novelly employ the belief propagation algorithm to facilitate label augmentation on graphs. Then, leveraging an auxiliary graph neural network and the gradient backpropagation method, our framework effectively extracts explanatory subgraphs surrounding target nodes. The final predictions are based on these informative subgraphs while mitigating the influence of redundant information from neighboring nodes. Extensive experiments on seven benchmark datasets demonstrate superior prediction accuracy, training efficiency, and explanation quality of BAED. As a pioneer, this work highlights the potential of the explanation-based research paradigm in FSGL.

Spatial Autoregressive Modeling of DINOv3 Embeddings for Unsupervised Anomaly Detection

DINO models provide rich patch-level representations that have recently enabled strong performance in unsupervised anomaly detection (UAD). Most existing methods extract patch embeddings from ``normal'' images and model them independently, ignoring spatial and neighborhood relationships between patches. This implicitly assumes that self-attention and positional encodings sufficiently encode contextual information within each patch embedding. In addition, the normative distribution is often modeled as memory banks or prototype-based representations, which require storing large numbers of features and performing costly comparisons at inference time, leading to substantial memory and computational overhead. In this work, we address both limitations by proposing a simple and efficient framework that explicitly models spatial and contextual dependencies between patch embeddings using a 2D autoregressive (AR) model. Instead of storing embeddings or clustering prototypes, our approach learns a compact parametric model of the normative distribution via an AR convolutional neural network (CNN). At test time, anomaly detection reduces to a single forward pass through the network and enables fast and memory-efficient inference. We evaluate our method on the BMAD benchmark, which comprises three medical imaging datasets, and compare it against existing work including recent DINO-based methods. Experimental results demonstrate that explicitly modeling spatial dependencies achieves competitive anomaly detection performance while substantially reducing inference time and memory requirements. Code is available at the project page: https://eerdil.github.io/spatial-ar-dinov3-uad/.

STMI: Segmentation-Guided Token Modulation with Cross-Modal Hypergraph Interaction for Multi-Modal Object Re-Identification

Multi-modal object Re-Identification (ReID) aims to exploit complementary information from different modalities to retrieve specific objects. However, existing methods often rely on hard token filtering or simple fusion strategies, which can lead to the loss of discriminative cues and increased background interference. To address these challenges, we propose STMI, a novel multi-modal learning framework consisting of three key components: (1) Segmentation-Guided Feature Modulation (SFM) module leverages SAM-generated masks to enhance foreground representations and suppress background noise through learnable attention modulation; (2) Semantic Token Reallocation (STR) module employs learnable query tokens and an adaptive reallocation mechanism to extract compact and informative representations without discarding any tokens; (3) Cross-Modal Hypergraph Interaction (CHI) module constructs a unified hypergraph across modalities to capture high-order semantic relationships. Extensive experiments on public benchmarks (i.e., RGBNT201, RGBNT100, and MSVR310) demonstrate the effectiveness and robustness of our proposed STMI framework in multi-modal ReID scenarios.

GENAI WORKBENCH: AI-Assisted Analysis and Synthesis of Engineering Systems from Multimodal Engineering Data

Modern engineering design platforms excel at discipline-specific tasks such as CAD, CAM, and CAE, but often lack native systems engineering frameworks. This creates a disconnect where system-level requirements and architectures are managed separately from detailed component design, hindering holistic development and increasing integration risks. To address this, we present the conceptual framework for the GenAI Workbench, a Model-Based Systems Engineering (MBSE) environment that integrates systems engineering principles into the designer's workflow. Built on an open-source PLM platform, it establishes a unified digital thread by linking semantic data from documents, physical B-rep geometry, and relational system graphs. The workbench facilitates an AI-assisted workflow where a designer can ingest source documents, from which the system automatically extracts requirements and uses vision-language models to generate an initial system architecture, such as a Design Structure Matrix (DSM). This paper presents the conceptual architecture, proposed methodology, and anticipated impact of this work-in-progress framework, which aims to foster a more integrated, data-driven, and informed engineering design methodology.

Adaptive Memory Admission Control for LLM Agents

LLM-based agents increasingly rely on long-term memory to support multi-session reasoning and interaction, yet current systems provide little control over what information is retained. In practice, agents either accumulate large volumes of conversational content, including hallucinated or obsolete facts, or depend on opaque, fully LLM-driven memory policies that are costly and difficult to audit. As a result, memory admission remains a poorly specified and weakly controlled component in agent architectures. To address this gap, we propose Adaptive Memory Admission Control (A-MAC), a framework that treats memory admission as a structured decision problem. A-MAC decomposes memory value into five complementary and interpretable factors: future utility, factual confidence, semantic novelty, temporal recency, and content type prior. The framework combines lightweight rule-based feature extraction with a single LLM-assisted utility assessment, and learns domain-adaptive admission policies through cross-validated optimization. This design enables transparent and efficient control over long-term memory. Experiments on the LoCoMo benchmark show that A-MAC achieves a superior precision-recall tradeoff, improving F1 to 0.583 while reducing latency by 31% compared to state-of-the-art LLM-native memory systems. Ablation results identify content type prior as the most influential factor for reliable memory admission. These findings demonstrate that explicit and interpretable admission control is a critical design principle for scalable and reliable memory in LLM-based agents.

HAMMER: Harnessing MLLM via Cross-Modal Integration for Intention-Driven 3D Affordance Grounding

Humans commonly identify 3D object affordance through observed interactions in images or videos, and once formed, such knowledge can be generically generalized to novel objects. Inspired by this principle, we advocate for a novel framework that leverages emerging multimodal large language models (MLLMs) for interaction intention-driven 3D affordance grounding, namely HAMMER. Instead of generating explicit object attribute descriptions or relying on off-the-shelf 2D segmenters, we alternatively aggregate the interaction intention depicted in the image into a contact-aware embedding and guide the model to infer textual affordance labels, ensuring it thoroughly excavates object semantics and contextual cues. We further devise a hierarchical cross-modal integration mechanism to fully exploit the complementary information from the MLLM for 3D representation refinement and introduce a multi-granular geometry lifting module that infuses spatial characteristics into the extracted intention embedding, thus facilitating accurate 3D affordance localization. Extensive experiments on public datasets and our newly constructed corrupted benchmark demonstrate the superiority and robustness of HAMMER compared to existing approaches. All code and weights are publicly available.

T2S-Bench & Structure-of-Thought: Benchmarking and Prompting Comprehensive Text-to-Structure Reasoning

Think about how human handles complex reading tasks: marking key points, inferring their relationships, and structuring information to guide understanding and responses. Likewise, can a large language model benefit from text structure to enhance text-processing performance? To explore it, in this work, we first introduce Structure of Thought (SoT), a prompting technique that explicitly guides models to construct intermediate text structures, consistently boosting performance across eight tasks and three model families. Building upon this insight, we present T2S-Bench, the first benchmark designed to evaluate and improve text-to-structure capabilities of models. T2S-Bench includes 1.8K samples across 6 scientific domains and 32 structural types, rigorously constructed to ensure accuracy, fairness, and quality. Evaluation on 45 mainstream models reveals substantial improvement potential: the average accuracy on the multi-hop reasoning task is only 52.1%, and even the most advanced model achieves 58.1% node accuracy in end-to-end extraction. Furthermore, on Qwen2.5-7B-Instruct, SoT alone yields an average +5.7% improvement across eight diverse text-processing tasks, and fine-tuning on T2S-Bench further increases this gain to +8.6%. These results highlight the value of explicit text structuring and the complementary contributions of SoT and T2S-Bench. Dataset and eval code have been released at https://t2s-bench.github.io/T2S-Bench-Page/.