TCMBench: A Comprehensive Benchmark for Evaluating Large Language Models in Traditional Chinese Medicine

Large language models (LLMs) have performed remarkably well in various natural language processing tasks by benchmarking, including in the Western medical domain. However, the professional evaluation benchmarks for LLMs have yet to be covered in the traditional Chinese medicine(TCM) domain, which has a profound history and vast influence. To address this research gap, we introduce TCM-Bench, an comprehensive benchmark for evaluating LLM performance in TCM. It comprises the TCM-ED dataset, consisting of 5,473 questions sourced from the TCM Licensing Exam (TCMLE), including 1,300 questions with authoritative analysis. It covers the core components of TCMLE, including TCM basis and clinical practice. To evaluate LLMs beyond accuracy of question answering, we propose TCMScore, a metric tailored for evaluating the quality of answers generated by LLMs for TCM related questions. It comprehensively considers the consistency of TCM semantics and knowledge. After conducting comprehensive experimental analyses from diverse perspectives, we can obtain the following findings: (1) The unsatisfactory performance of LLMs on this benchmark underscores their significant room for improvement in TCM. (2) Introducing domain knowledge can enhance LLMs' performance. However, for in-domain models like ZhongJing-TCM, the quality of generated analysis text has decreased, and we hypothesize that their fine-tuning process affects the basic LLM capabilities. (3) Traditional metrics for text generation quality like Rouge and BertScore are susceptible to text length and surface semantic ambiguity, while domain-specific metrics such as TCMScore can further supplement and explain their evaluation results. These findings highlight the capabilities and limitations of LLMs in the TCM and aim to provide a more profound assistance to medical research.

IAPT: Instruction-Aware Prompt Tuning for Large Language Models

Soft prompt tuning is a widely studied parameter-efficient fine-tuning method. However, it has a clear drawback: many soft tokens must be inserted into the input sequences to guarantee downstream performance. As a result, soft prompt tuning is less considered than Low-rank adaptation (LoRA) in the large language modeling (LLM) era. In this work, we propose a novel prompt tuning method, Instruction-Aware Prompt Tuning (IAPT), that requires only four soft tokens. First, we install a parameter-efficient soft prompt generator at each Transformer layer to generate idiosyncratic soft prompts for each input instruction. The generated soft prompts can be seen as a semantic summary of the input instructions and can effectively guide the output generation. Second, the soft prompt generators are modules with a bottleneck architecture consisting of a self-attention pooling operation, two linear projections, and an activation function. Pilot experiments show that prompt generators at different Transformer layers require different activation functions. Thus, we propose to learn the idiosyncratic activation functions for prompt generators automatically with the help of rational functions. We have conducted experiments on various tasks, and the experimental results demonstrate that (a) our IAPT method can outperform the recent baselines with comparable tunable parameters. (b) Our IAPT method is more efficient than LoRA under the single-backbone multi-tenant setting.

Nonlinear denoising score matching for enhanced learning of structured distributions

We present a novel method for training score-based generative models which uses nonlinear noising dynamics to improve learning of structured distributions. Generalizing to a nonlinear drift allows for additional structure to be incorporated into the dynamics, thus making the training better adapted to the data, e.g., in the case of multimodality or (approximate) symmetries. Such structure can be obtained from the data by an inexpensive preprocessing step. The nonlinear dynamics introduces new challenges into training which we address in two ways: 1) we develop a new nonlinear denoising score matching (NDSM) method, 2) we introduce neural control variates in order to reduce the variance of the NDSM training objective. We demonstrate the effectiveness of this method on several examples: a) a collection of low-dimensional examples, motivated by clustering in latent space, b) high-dimensional images, addressing issues with mode collapse, small training sets, and approximate symmetries, the latter being a challenge for methods based on equivariant neural networks, which require exact symmetries.

Learning heavy-tailed distributions with Wasserstein-proximal-regularized $α$-divergences

In this paper, we propose Wasserstein proximals of $\alpha$-divergences as suitable objective functionals for learning heavy-tailed distributions in a stable manner. First, we provide sufficient, and in some cases necessary, relations among data dimension, $\alpha$, and the decay rate of data distributions for the Wasserstein-proximal-regularized divergence to be finite. Finite-sample convergence rates for the estimation in the case of the Wasserstein-1 proximal divergences are then provided under certain tail conditions. Numerical experiments demonstrate stable learning of heavy-tailed distributions -- even those without first or second moment -- without any explicit knowledge of the tail behavior, using suitable generative models such as GANs and flow-based models related to our proposed Wasserstein-proximal-regularized $\alpha$-divergences. Heuristically, $\alpha$-divergences handle the heavy tails and Wasserstein proximals allow non-absolute continuity between distributions and control the velocities of flow-based algorithms as they learn the target distribution deep into the tails.

ALoRA: Allocating Low-Rank Adaptation for Fine-tuning Large Language Models

Parameter-efficient fine-tuning (PEFT) is widely studied for its effectiveness and efficiency in the era of large language models. Low-rank adaptation (LoRA) has demonstrated commendable performance as a popular and representative method. However, it is implemented with a fixed intrinsic rank that might not be the ideal setting for the downstream tasks. Recognizing the need for more flexible downstream task adaptation, we extend the methodology of LoRA to an innovative approach we call allocating low-rank adaptation (ALoRA) that enables dynamic adjustments to the intrinsic rank during the adaptation process. First, we propose a novel method, AB-LoRA, that can effectively estimate the importance score of each LoRA rank. Second, guided by AB-LoRA, we gradually prune abundant and negatively impacting LoRA ranks and allocate the pruned LoRA budgets to important Transformer modules needing higher ranks. We have conducted experiments on various tasks, and the experimental results demonstrate that our ALoRA method can outperform the recent baselines with comparable tunable parameters.

Text2MDT: Extracting Medical Decision Trees from Medical Texts

Knowledge of the medical decision process, which can be modeled as medical decision trees (MDTs), is critical to build clinical decision support systems. However, the current MDT construction methods rely heavily on time-consuming and laborious manual annotation. In this work, we propose a novel task, Text2MDT, to explore the automatic extraction of MDTs from medical texts such as medical guidelines and textbooks. We normalize the form of the MDT and create an annotated Text-to-MDT dataset in Chinese with the participation of medical experts. We investigate two different methods for the Text2MDT tasks: (a) an end-to-end framework which only relies on a GPT style large language models (LLM) instruction tuning to generate all the node information and tree structures. (b) The pipeline framework which decomposes the Text2MDT task to three subtasks. Experiments on our Text2MDT dataset demonstrate that: (a) the end-to-end method basd on LLMs (7B parameters or larger) show promising results, and successfully outperform the pipeline methods. (b) The chain-of-thought (COT) prompting method \cite{Wei2022ChainOT} can improve the performance of the fine-tuned LLMs on the Text2MDT test set. (c) the lightweight pipelined method based on encoder-based pretrained models can perform comparably with LLMs with model complexity two magnititudes smaller. Our Text2MDT dataset is open-sourced at \url{https://tianchi.aliyun.com/dataset/95414}, and the source codes are open-sourced at \url{https://github.com/michael-wzhu/text2dt}.

Efficient Multi-domain Text Recognition Deep Neural Network Parameterization with Residual Adapters

Recent advancements in deep neural networks have markedly enhanced the performance of computer vision tasks, yet the specialized nature of these networks often necessitates extensive data and high computational power. Addressing these requirements, this study presents a novel neural network model adept at optical character recognition (OCR) across diverse domains, leveraging the strengths of multi-task learning to improve efficiency and generalization. The model is designed to achieve rapid adaptation to new domains, maintain a compact size conducive to reduced computational resource demand, ensure high accuracy, retain knowledge from previous learning experiences, and allow for domain-specific performance improvements without the need to retrain entirely. Rigorous evaluation on open datasets has validated the model's ability to significantly lower the number of trainable parameters without sacrificing performance, indicating its potential as a scalable and adaptable solution in the field of computer vision, particularly for applications in optical text recognition.

Overview of the PromptCBLUE Shared Task in CHIP2023

This paper presents an overview of the PromptCBLUE shared task (http://cips-chip.org.cn/2023/eval1) held in the CHIP-2023 Conference. This shared task reformualtes the CBLUE benchmark, and provide a good testbed for Chinese open-domain or medical-domain large language models (LLMs) in general medical natural language processing. Two different tracks are held: (a) prompt tuning track, investigating the multitask prompt tuning of LLMs, (b) probing the in-context learning capabilities of open-sourced LLMs. Many teams from both the industry and academia participated in the shared tasks, and the top teams achieved amazing test results. This paper describes the tasks, the datasets, evaluation metrics, and the top systems for both tasks. Finally, the paper summarizes the techniques and results of the evaluation of the various approaches explored by the participating teams.

Improving Prompt Tuning with Learned Prompting Layers

Prompt tuning prepends a soft prompt to the input embeddings or hidden states and only optimizes the prompt to adapt pretrained models (PTMs) to downstream tasks. The previous work manually selects prompt layers which are far from optimal and failed to exploit the potential of prompt tuning. In this work, we propose a novel framework, \underline{S}elective \underline{P}rompt \underline{T}uning (SPT), that learns to select the proper prompt layers by inserting a prompt controlled by a learnable probabilistic gate at each intermediate layer. We further propose a novel bi-level optimization framework, SPT-DARTS, that can better optimize the learnable gates and improve the final prompt tuning performances of the learned prompt layer settings. We conduct extensive experiments with ten benchmark datasets under the full-data and few-shot scenarios. The results demonstrate that our SPT framework can perform better than the previous state-of-the-art PETuning baselines with comparable or fewer tunable parameters.

PromptCBLUE: A Chinese Prompt Tuning Benchmark for the Medical Domain

Biomedical language understanding benchmarks are the driving forces for artificial intelligence applications with large language model (LLM) back-ends. However, most current benchmarks: (a) are limited to English which makes it challenging to replicate many of the successes in English for other languages, or (b) focus on knowledge probing of LLMs and neglect to evaluate how LLMs apply these knowledge to perform on a wide range of bio-medical tasks, or (c) have become a publicly available corpus and are leaked to LLMs during pre-training. To facilitate the research in medical LLMs, we re-build the Chinese Biomedical Language Understanding Evaluation (CBLUE) benchmark into a large scale prompt-tuning benchmark, PromptCBLUE. Our benchmark is a suitable test-bed and an online platform for evaluating Chinese LLMs' multi-task capabilities on a wide range bio-medical tasks including medical entity recognition, medical text classification, medical natural language inference, medical dialogue understanding and medical content/dialogue generation. To establish evaluation on these tasks, we have experimented and report the results with the current 9 Chinese LLMs fine-tuned with differtent fine-tuning techniques.