The Vehicle Routing Problem (VRP) is one of the most intensively studied combinatorial optimisation problems for which numerous models and algorithms have been proposed. To tackle the complexities, uncertainties and dynamics involved in real-world VRP applications, Machine Learning (ML) methods have been used in combination with analytical approaches to enhance problem formulations and algorithmic performance across different problem solving scenarios. However, the relevant papers are scattered in several traditional research fields with very different, sometimes confusing, terminologies. This paper presents a first, comprehensive review of hybrid methods that combine analytical techniques with ML tools in addressing VRP problems. Specifically, we review the emerging research streams on ML-assisted VRP modelling and ML-assisted VRP optimisation. We conclude that ML can be beneficial in enhancing VRP modelling, and improving the performance of algorithms for both online and offline VRP optimisations. Finally, challenges and future opportunities of VRP research are discussed.
In this paper, we propose a rule-based engine composed of high quality and interpretable regular expressions for medical text classification. The regular expressions are auto generated by a constructive heuristic method and optimized using a Pool-based Simulated Annealing (PSA) approach. Although existing Deep Neural Network (DNN) methods present high quality performance in most Natural Language Processing (NLP) applications, the solutions are regarded as uninterpretable black boxes to humans. Therefore, rule-based methods are often introduced when interpretable solutions are needed, especially in the medical field. However, the construction of regular expressions can be extremely labor-intensive for large data sets. This research aims to reduce the manual efforts while maintaining high-quality solutions
Internet hospital is a rising business thanks to recent advances in mobile web technology and high demand of health care services. Online medical services become increasingly popular and active. According to US data in 2018, 80 percent of internet users have asked health-related questions online. Numerous data is generated in unprecedented speed and scale. Those representative questions and answers in medical fields are valuable raw data sources for medical data mining. Automated machine interpretation on those sheer amount of data gives an opportunity to assist doctors to answer frequently asked medical-related questions from the perspective of information retrieval and machine learning approaches. In this work, we propose a novel two-stage framework for the semantic matching of query-level medical questions.
The detection of cell shape changes in 3D time-lapse images of complex tissues is an important task. However, it is a challenging and tedious task to establish a comprehensive dataset to improve the performance of deep learning models. In the paper, we present a deep learning approach to augment 3D live images of the Caenorhabditis elegans embryo, so that we can further speed up the specific structural pattern recognition. We use an unsupervised training over unlabeled images to generate supplementary datasets for further pattern recognition. Technically, we used Alex-style neural networks in a generative adversarial network framework to generate new datasets that have common features of the C. elegans membrane structure. We also made the dataset available for a broad scientific community.