Assessing the Usability of GutGPT: A Simulation Study of an AI Clinical Decision Support System for Gastrointestinal Bleeding Risk

Applications of large language models (LLMs) like ChatGPT have potential to enhance clinical decision support through conversational interfaces. However, challenges of human-algorithmic interaction and clinician trust are poorly understood. GutGPT, a LLM for gastrointestinal (GI) bleeding risk prediction and management guidance, was deployed in clinical simulation scenarios alongside the electronic health record (EHR) with emergency medicine physicians, internal medicine physicians, and medical students to evaluate its effect on physician acceptance and trust in AI clinical decision support systems (AI-CDSS). GutGPT provides risk predictions from a validated machine learning model and evidence-based answers by querying extracted clinical guidelines. Participants were randomized to GutGPT and an interactive dashboard, or the interactive dashboard and a search engine. Surveys and educational assessments taken before and after measured technology acceptance and content mastery. Preliminary results showed mixed effects on acceptance after using GutGPT compared to the dashboard or search engine but appeared to improve content mastery based on simulation performance. Overall, this study demonstrates LLMs like GutGPT could enhance effective AI-CDSS if implemented optimally and paired with interactive interfaces.

LightZero: A Unified Benchmark for Monte Carlo Tree Search in General Sequential Decision Scenarios

Building agents based on tree-search planning capabilities with learned models has achieved remarkable success in classic decision-making problems, such as Go and Atari. However, it has been deemed challenging or even infeasible to extend Monte Carlo Tree Search (MCTS) based algorithms to diverse real-world applications, especially when these environments involve complex action spaces and significant simulation costs, or inherent stochasticity. In this work, we introduce LightZero, the first unified benchmark for deploying MCTS/MuZero in general sequential decision scenarios. Specificially, we summarize the most critical challenges in designing a general MCTS-style decision-making solver, then decompose the tightly-coupled algorithm and system design of tree-search RL methods into distinct sub-modules. By incorporating more appropriate exploration and optimization strategies, we can significantly enhance these sub-modules and construct powerful LightZero agents to tackle tasks across a wide range of domains, such as board games, Atari, MuJoCo, MiniGrid and GoBigger. Detailed benchmark results reveal the significant potential of such methods in building scalable and efficient decision intelligence. The code is available as part of OpenDILab at https://github.com/opendilab/LightZero.

Context-Based Soft Actor Critic for Environments with Non-stationary Dynamics

The performance of deep reinforcement learning methods prone to degenerate when applied to environments with non-stationary dynamics. In this paper, we utilize the latent context recurrent encoders motivated by recent Meta-RL materials, and propose the Latent Context-based Soft Actor Critic (LC-SAC) method to address aforementioned issues. By minimizing the contrastive prediction loss function, the learned context variables capture the information of the environment dynamics and the recent behavior of the agent. Then combined with the soft policy iteration paradigm, the LC-SAC method alternates between soft policy evaluation and soft policy improvement until it converges to the optimal policy. Experimental results show that the performance of LC-SAC is significantly better than the SAC algorithm on the MetaWorld ML1 tasks whose dynamics changes drasticly among different episodes, and is comparable to SAC on the continuous control benchmark task MuJoCo whose dynamics changes slowly or doesn't change between different episodes. In addition, we also conduct relevant experiments to determine the impact of different hyperparameter settings on the performance of the LC-SAC algorithm and give the reasonable suggestions of hyperparameter setting.

Decomposed Soft Actor-Critic Method for Cooperative Multi-Agent Reinforcement Learning

Deep reinforcement learning methods have shown great performance on many challenging cooperative multi-agent tasks. Two main promising research directions are multi-agent value function decomposition and multi-agent policy gradients. In this paper, we propose a new decomposed multi-agent soft actor-critic (mSAC) method, which effectively combines the advantages of the aforementioned two methods. The main modules include decomposed Q network architecture, discrete probabilistic policy and counterfactual advantage function (optinal). Theoretically, mSAC supports efficient off-policy learning and addresses credit assignment problem partially in both discrete and continuous action spaces. Tested on StarCraft II micromanagement cooperative multiagent benchmark, we empirically investigate the performance of mSAC against its variants and analyze the effects of the different components. Experimental results demonstrate that mSAC significantly outperforms policy-based approach COMA, and achieves competitive results with SOTA value-based approach Qmix on most tasks in terms of asymptotic perfomance metric. In addition, mSAC achieves pretty good results on large action space tasks, such as 2c_vs_64zg and MMM2.