ViP$^2$-CLIP: Visual-Perception Prompting with Unified Alignment for Zero-Shot Anomaly Detection

Zero-shot anomaly detection (ZSAD) aims to detect anomalies without any target domain training samples, relying solely on external auxiliary data. Existing CLIP-based methods attempt to activate the model's ZSAD potential via handcrafted or static learnable prompts. The former incur high engineering costs and limited semantic coverage, whereas the latter apply identical descriptions across diverse anomaly types, thus fail to adapt to complex variations. Furthermore, since CLIP is originally pretrained on large-scale classification tasks, its anomaly segmentation quality is highly sensitive to the exact wording of class names, severely constraining prompting strategies that depend on class labels. To address these challenges, we introduce ViP$^{2}$-CLIP. The key insight of ViP$^{2}$-CLIP is a Visual-Perception Prompting (ViP-Prompt) mechanism, which fuses global and multi-scale local visual context to adaptively generate fine-grained textual prompts, eliminating manual templates and class-name priors. This design enables our model to focus on precise abnormal regions, making it particularly valuable when category labels are ambiguous or privacy-constrained. Extensive experiments on 15 industrial and medical benchmarks demonstrate that ViP$^{2}$-CLIP achieves state-of-the-art performance and robust cross-domain generalization.

LLaVA-RadZ: Can Multimodal Large Language Models Effectively Tackle Zero-shot Radiology Recognition?

Recently, multimodal large models (MLLMs) have demonstrated exceptional capabilities in visual understanding and reasoning across various vision-language tasks. However, MLLMs usually perform poorly in zero-shot medical disease recognition, as they do not fully exploit the captured features and available medical knowledge. To address this challenge, we propose LLaVA-RadZ, a simple yet effective framework for zero-shot medical disease recognition. Specifically, we design an end-to-end training strategy, termed Decoding-Side Feature Alignment Training (DFAT) to take advantage of the characteristics of the MLLM decoder architecture and incorporate modality-specific tokens tailored for different modalities, which effectively utilizes image and text representations and facilitates robust cross-modal alignment. Additionally, we introduce a Domain Knowledge Anchoring Module (DKAM) to exploit the intrinsic medical knowledge of large models, which mitigates the category semantic gap in image-text alignment. DKAM improves category-level alignment, allowing for accurate disease recognition. Extensive experiments on multiple benchmarks demonstrate that our LLaVA-RadZ significantly outperforms traditional MLLMs in zero-shot disease recognition and exhibits the state-of-the-art performance compared to the well-established and highly-optimized CLIP-based approaches.