OxygenREC-v2: Internalizing Discrimination into Generative Recommendation

Generative recommendation unifies retrieval and ranking within a single model by autoregressively decoding semantic identifier (SID) sequences. Yet reliably incorporating behavior signals from clicks, cart additions, and orders remains challenging. Existing approaches either jointly optimize generative and discriminative objectives, requiring delicate trade-offs, or use a separate ranker as a post-hoc reinforcement-learning reward, risking out-of-distribution scoring and reward misalignment. We propose OxygenREC-v2, a generative recommender that Internalizes Discrimination into Generative Recommendation (IDGR). Rather than adding a separate discriminative objective, OxygenREC-v2 uses logged behavior to condition generation and supervise training. During pre-training, a behavior instruction conditions generation on the target behavior. During post-training, future interaction behaviors are exploited as privileged knowledge in our entropy-aware trajectory optimization self-distillation framework, enabling reward-model-free policy optimization. Throughout both training stages, OxygenREC-v2 maintains a single unified backbone. We implement OxygenREC-v2 as a 3B-parameter, 1B-activated MoE and deploy it on JD.com's large-scale e-commerce platform. Across multiple online A/B tests, OxygenREC-v2 improves user click-through conversion rate (UCTCVR) by 1.6--4.4% and GMV by 2.8--6.8% over OxygenREC-v1.

A Zero-Shot Deep Image Prior Framework for Denoising and Deconvolution in Fluorescence Microscopy

Fluorescence microscopy images are degraded by noise and diffraction-induced blur, which compromise structural fidelity and limit quantitative analysis. Supervised deep learning methods achieve impressive restoration performance but require large-scale paired datasets that are difficult to obtain in practice. To address this issue, we propose SDIP, a zero-shot deep image prior (DIP) framework that sequentially performs denoising and deconvolution without external training data. An aSeqDIP-based module first suppresses noise while preserving fine structures through sequential autoencoding regularization. In the deconvolution stage, a wavelet-based background correction step is incorporated before the proposed RLG-DIP module performs artifact-reduced deconvolution. RLG-DIP uses the Richardson-Lucy deconvolution result as a physically consistent guidance prior, integrating the imaging model with the implicit prior of DIP to stabilize the ill-posed deconvolution process. Experiments on the BioSR dataset across multiple cellular structures demonstrate that SDIP improves both signal-to-noise ratio and resolution, achieving superior visual quality and improved quantitative performance on most evaluated structures. The proposed framework may also provide useful insights for designing physically guided DIP methods for other inverse problems.

OxygenREC: An Instruction-Following Generative Framework for E-commerce Recommendation

Traditional recommendation systems suffer from inconsistency in multi-stage optimization objectives. Generative Recommendation (GR) mitigates them through an end-to-end framework; however, existing methods still rely on matching mechanisms based on inductive patterns. Although responsive, they lack the ability to uncover complex user intents that require deductive reasoning based on world knowledge. Meanwhile, LLMs show strong deep reasoning capabilities, but their latency and computational costs remain challenging for industrial applications. More critically, there are performance bottlenecks in multi-scenario scalability: as shown in Figure 1, existing solutions require independent training and deployment for each scenario, leading to low resource utilization and high maintenance costs-a challenge unaddressed in GR literature. To address these, we present OxygenREC, an industrial recommendation system that leverages Fast-Slow Thinking to deliver deep reasoning with strict latency and multi-scenario requirements of real-world environments. First, we adopt a Fast-Slow Thinking architecture. Slow thinking uses a near-line LLM pipeline to synthesize Contextual Reasoning Instructions, while fast thinking employs a high-efficiency encoder-decoder backbone for real-time generation. Second, to ensure reasoning instructions effectively enhance recommendation generation, we introduce a semantic alignment mechanism with Instruction-Guided Retrieval (IGR) to filter intent-relevant historical behaviors and use a Query-to-Item (Q2I) loss for instruction-item consistency. Finally, to resolve multi-scenario scalability, we transform scenario information into controllable instructions, using unified reward mapping and Soft Adaptive Group Clip Policy Optimization (SA-GCPO) to align policies with diverse business objectives, realizing a train-once-deploy-everywhere paradigm.