Sequential Diagnosis Prediction with Transformer and Ontological Representation

Sequential diagnosis prediction on the Electronic Health Record (EHR) has been proven crucial for predictive analytics in the medical domain. EHR data, sequential records of a patient's interactions with healthcare systems, has numerous inherent characteristics of temporality, irregularity and data insufficiency. Some recent works train healthcare predictive models by making use of sequential information in EHR data, but they are vulnerable to irregular, temporal EHR data with the states of admission/discharge from hospital, and insufficient data. To mitigate this, we propose an end-to-end robust transformer-based model called SETOR, which exploits neural ordinary differential equation to handle both irregular intervals between a patient's visits with admitted timestamps and length of stay in each visit, to alleviate the limitation of insufficient data by integrating medical ontology, and to capture the dependencies between the patient's visits by employing multi-layer transformer blocks. Experiments conducted on two real-world healthcare datasets show that, our sequential diagnoses prediction model SETOR not only achieves better predictive results than previous state-of-the-art approaches, irrespective of sufficient or insufficient training data, but also derives more interpretable embeddings of medical codes. The experimental codes are available at the GitHub repository (https://github.com/Xueping/SETOR).

Federated Learning for Privacy-Preserving Open Innovation Future on Digital Health

Privacy protection is an ethical issue with broad concern in Artificial Intelligence (AI). Federated learning is a new machine learning paradigm to learn a shared model across users or organisations without direct access to the data. It has great potential to be the next-general AI model training framework that offers privacy protection and therefore has broad implications for the future of digital health and healthcare informatics. Implementing an open innovation framework in the healthcare industry, namely open health, is to enhance innovation and creative capability of health-related organisations by building a next-generation collaborative framework with partner organisations and the research community. In particular, this game-changing collaborative framework offers knowledge sharing from diverse data with a privacy-preserving. This chapter will discuss how federated learning can enable the development of an open health ecosystem with the support of AI. Existing challenges and solutions for federated learning will be discussed.

Federated Learning for Open Banking

Open banking enables individual customers to own their banking data, which provides fundamental support for the boosting of a new ecosystem of data marketplaces and financial services. In the near future, it is foreseeable to have decentralized data ownership in the finance sector using federated learning. This is a just-in-time technology that can learn intelligent models in a decentralized training manner. The most attractive aspect of federated learning is its ability to decompose model training into a centralized server and distributed nodes without collecting private data. This kind of decomposed learning framework has great potential to protect users' privacy and sensitive data. Therefore, federated learning combines naturally with an open banking data marketplaces. This chapter will discuss the possible challenges for applying federated learning in the context of open banking, and the corresponding solutions have been explored as well.

Multi-Center Federated Learning

Federated learning (FL) can protect data privacy in distributed learning since it merely collects local gradients from users without access to their data. However, FL is fragile in the presence of heterogeneity that is commonly encountered in practical settings, e.g., non-IID data over different users. Existing FL approaches usually update a single global model to capture the shared knowledge of all users by aggregating their gradients, regardless of the discrepancy between their data distributions. By comparison, a mixture of multiple global models could capture the heterogeneity across various users if assigning the users to different global models (i.e., centers) in FL. To this end, we propose a novel multi-center aggregation mechanism . It learns multiple global models from data, and simultaneously derives the optimal matching between users and centers. We then formulate it as a bi-level optimization problem that can be efficiently solved by a stochastic expectation maximization (EM) algorithm. Experiments on multiple benchmark datasets of FL show that our method outperforms several popular FL competitors. The source code are open source on Github.

Complex Knowledge Base Question Answering: A Survey

Knowledge base question answering (KBQA) aims to answer a question over a knowledge base (KB). Early studies mainly focused on answering simple questions over KBs and achieved great success. However, their performance on complex questions is still far from satisfactory. Therefore, in recent years, researchers propose a large number of novel methods, which looked into the challenges of answering complex questions. In this survey, we review recent advances on KBQA with the focus on solving complex questions, which usually contain multiple subjects, express compound relations, or involve numerical operations. In detail, we begin with introducing the complex KBQA task and relevant background. Then, we describe benchmark datasets for complex KBQA task and introduce the construction process of these datasets. Next, we present two mainstream categories of methods for complex KBQA, namely semantic parsing-based (SP-based) methods and information retrieval-based (IR-based) methods. Specifically, we illustrate their procedures with flow designs and discuss their major differences and similarities. After that, we summarize the challenges that these two categories of methods encounter when answering complex questions, and explicate advanced solutions and techniques used in existing work. Finally, we conclude and discuss several promising directions related to complex KBQA for future research.

Disentangling Hate in Online Memes

Hateful and offensive content detection has been extensively explored in a single modality such as text. However, such toxic information could also be communicated via multimodal content such as online memes. Therefore, detecting multimodal hateful content has recently garnered much attention in academic and industry research communities. This paper aims to contribute to this emerging research topic by proposing DisMultiHate, which is a novel framework that performed the classification of multimodal hateful content. Specifically, DisMultiHate is designed to disentangle target entities in multimodal memes to improve hateful content classification and explainability. We conduct extensive experiments on two publicly available hateful and offensive memes datasets. Our experiment results show that DisMultiHate is able to outperform state-of-the-art unimodal and multimodal baselines in the hateful meme classification task. Empirical case studies were also conducted to demonstrate DisMultiHate's ability to disentangle target entities in memes and ultimately showcase DisMultiHate's explainability of the multimodal hateful content classification task.

Beyond Low-pass Filtering: Graph Convolutional Networks with Automatic Filtering

Graph convolutional networks are becoming indispensable for deep learning from graph-structured data. Most of the existing graph convolutional networks share two big shortcomings. First, they are essentially low-pass filters, thus the potentially useful middle and high frequency band of graph signals are ignored. Second, the bandwidth of existing graph convolutional filters is fixed. Parameters of a graph convolutional filter only transform the graph inputs without changing the curvature of a graph convolutional filter function. In reality, we are uncertain about whether we should retain or cut off the frequency at a certain point unless we have expert domain knowledge. In this paper, we propose Automatic Graph Convolutional Networks (AutoGCN) to capture the full spectrum of graph signals and automatically update the bandwidth of graph convolutional filters. While it is based on graph spectral theory, our AutoGCN is also localized in space and has a spatial form. Experimental results show that AutoGCN achieves significant improvement over baseline methods which only work as low-pass filters.

Order-Agnostic Cross Entropy for Non-Autoregressive Machine Translation

We propose a new training objective named order-agnostic cross entropy (OaXE) for fully non-autoregressive translation (NAT) models. OaXE improves the standard cross-entropy loss to ameliorate the effect of word reordering, which is a common source of the critical multimodality problem in NAT. Concretely, OaXE removes the penalty for word order errors, and computes the cross entropy loss based on the best possible alignment between model predictions and target tokens. Since the log loss is very sensitive to invalid references, we leverage cross entropy initialization and loss truncation to ensure the model focuses on a good part of the search space. Extensive experiments on major WMT benchmarks show that OaXE substantially improves translation performance, setting new state of the art for fully NAT models. Further analyses show that OaXE alleviates the multimodality problem by reducing token repetitions and increasing prediction confidence. Our code, data, and trained models are available at https://github.com/tencent-ailab/ICML21_OAXE.

A Survey on Complex Knowledge Base Question Answering: Methods, Challenges and Solutions

Knowledge base question answering (KBQA) aims to answer a question over a knowledge base (KB). Recently, a large number of studies focus on semantically or syntactically complicated questions. In this paper, we elaborately summarize the typical challenges and solutions for complex KBQA. We begin with introducing the background about the KBQA task. Next, we present the two mainstream categories of methods for complex KBQA, namely semantic parsing-based (SP-based) methods and information retrieval-based (IR-based) methods. We then review the advanced methods comprehensively from the perspective of the two categories. Specifically, we explicate their solutions to the typical challenges. Finally, we conclude and discuss some promising directions for future research.