Universal Lesion Detection (ULD) in computed tomography plays an essential role in computer-aided diagnosis systems. Many detection approaches achieve excellent results for ULD using possible bounding boxes (or anchors) as proposals. However, empirical evidence shows that using anchor-based proposals leads to a high false-positive (FP) rate. In this paper, we propose a box-to-map method to represent a bounding box with three soft continuous maps with bounds in x-, y- and xy- directions. The bounding maps (BMs) are used in two-stage anchor-based ULD frameworks to reduce the FP rate. In the 1 st stage of the region proposal network, we replace the sharp binary ground-truth label of anchors with the corresponding xy-direction BM hence the positive anchors are now graded. In the 2 nd stage, we add a branch that takes our continuous BMs in x- and y- directions for extra supervision of detailed locations. Our method, when embedded into three state-of-the-art two-stage anchor-based detection methods, brings a free detection accuracy improvement (e.g., a 1.68% to 3.85% boost of sensitivity at 4 FPs) without extra inference time.
Remote physiological measurements, e.g., remote photoplethysmography (rPPG) based heart rate (HR), heart rate variability (HRV) and respiration frequency (RF) measuring, are playing more and more important roles under the application scenarios where contact measurement is inconvenient or impossible. Since the amplitude of the physiological signals is very small, they can be easily affected by head movements, lighting conditions, and sensor diversities. To address these challenges, we propose a cross-verified feature disentangling strategy to disentangle the physiological features with non-physiological representations, and then use the distilled physiological features for robust multi-task physiological measurements. We first transform the input face videos into a multi-scale spatial-temporal map (MSTmap), which can suppress the irrelevant background and noise features while retaining most of the temporal characteristics of the periodic physiological signals. Then we take pairwise MSTmaps as inputs to an autoencoder architecture with two encoders (one for physiological signals and the other for non-physiological information) and use a cross-verified scheme to obtain physiological features disentangled with the non-physiological features. The disentangled features are finally used for the joint prediction of multiple physiological signals like average HR values and rPPG signals. Comprehensive experiments on different large-scale public datasets of multiple physiological measurement tasks as well as the cross-database testing demonstrate the robustness of our approach.
Recent methods in multiple landmark detection based on deep convolutional neural networks (CNNs) reach high accuracy and improve traditional clinical workflow. However, the vulnerability of CNNs to adversarial-example attacks can be easily exploited to break classification and segmentation tasks. This paper is the first to study how fragile a CNN-based model on multiple landmark detection to adversarial perturbations. Specifically, we propose a novel Adaptive Targeted Iterative FGSM (ATI-FGSM) attack against the state-of-the-art models in multiple landmark detection. The attacker can use ATI-FGSM to precisely control the model predictions of arbitrarily selected landmarks, while keeping other stationary landmarks still, by adding imperceptible perturbations to the original image. A comprehensive evaluation on a public dataset for cephalometric landmark detection demonstrates that the adversarial examples generated by ATI-FGSM break the CNN-based network more effectively and efficiently, compared with the original Iterative FGSM attack. Our work reveals serious threats to patients' health. Furthermore, we discuss the limitations of our method and provide potential defense directions, by investigating the coupling effect of nearby landmarks, i.e., a major source of divergence in our experiments. Our source code is available at https://github.com/qsyao/attack_landmark_detection.
With the mushrooming use of computed tomography (CT) images in clinical decision making, management of CT data becomes increasingly difficult. From the patient identification perspective, using the standard DICOM tag to track patient information is challenged by issues such as misspelling, lost file, site variation, etc. In this paper, we explore the feasibility of leveraging the faces in 3D CT images as biometric features. Specifically, we propose an automatic processing pipeline that first detects facial landmarks in 3D for ROI extraction and then generates aligned 2D depth images, which are used for automatic recognition. To boost the recognition performance, we employ transfer learning to reduce the data sparsity issue and to introduce a group sampling strategy to increase inter-class discrimination when training the recognition network. Our proposed method is capable of capturing underlying identity characteristics in medical images while reducing memory consumption. To test its effectiveness, we curate 600 3D CT images of 280 patients from multiple sources for performance evaluation. Experimental results demonstrate that our method achieves a 1:56 identification accuracy of 92.53% and a 1:1 verification accuracy of 96.12%, outperforming other competing approaches.
Face presentation attack detection (PAD) has been an urgent problem to be solved in the face recognition systems. Conventional approaches usually assume the testing and training are within the same domain; as a result, they may not generalize well into unseen scenarios because the representations learned for PAD may overfit to the subjects in the training set. In light of this, we propose an efficient disentangled representation learning for cross-domain face PAD. Our approach consists of disentangled representation learning (DR-Net) and multi-domain learning (MD-Net). DR-Net learns a pair of encoders via generative models that can disentangle PAD informative features from subject discriminative features. The disentangled features from different domains are fed to MD-Net which learns domain-independent features for the final cross-domain face PAD task. Extensive experiments on several public datasets validate the effectiveness of the proposed approach for cross-domain PAD.
Remote measurement of physiological signals from videos is an emerging topic. The topic draws great interests, but the lack of publicly available benchmark databases and a fair validation platform are hindering its further development. For this concern, we organize the first challenge on Remote Physiological Signal Sensing (RePSS), in which two databases of VIPL and OBF are provided as the benchmark for kin researchers to evaluate their approaches. The 1st challenge of RePSS focuses on measuring the average heart rate from facial videos, which is the basic problem of remote physiological measurement. This paper presents an overview of the challenge, including data, protocol, analysis of results and discussion. The top ranked solutions are highlighted to provide insights for researchers, and future directions are outlined for this topic and this challenge.
Combined variations containing low-resolution and occlusion often present in face images in the wild, e.g., under the scenario of video surveillance. While most of the existing face image recovery approaches can handle only one type of variation per model, in this work, we propose a deep generative adversarial network (FCSR-GAN) for performing joint face completion and face super-resolution via multi-task learning. The generator of FCSR-GAN aims to recover a high-resolution face image without occlusion given an input low-resolution face image with occlusion. The discriminator of FCSR-GAN uses a set of carefully designed losses (an adversarial loss, a perceptual loss, a pixel loss, a smooth loss, a style loss, and a face prior loss) to assure the high quality of the recovered high-resolution face images without occlusion. The whole network of FCSR-GAN can be trained end-to-end using our two-stage training strategy. Experimental results on the public-domain CelebA and Helen databases show that the proposed approach outperforms the state-of-the-art methods in jointly performing face super-resolution (up to 8 $\times$) and face completion, and shows good generalization ability in cross-database testing. Our FCSR-GAN is also useful for improving face identification performance when there are low-resolution and occlusion in face images.
Heart rate (HR) is an important physiological signal that reflects the physical and emotional status of a person. Traditional HR measurements usually rely on contact monitors, which may cause inconvenience and discomfort. Recently, some methods have been proposed for remote HR estimation from face videos; however, most of them focus on well-controlled scenarios, their generalization ability into less-constrained scenarios (e.g., with head movement, and bad illumination) are not known. At the same time, lacking large-scale HR databases has limited the use of deep models for remote HR estimation. In this paper, we propose an end-to-end RhythmNet for remote HR estimation from the face. In RyhthmNet, we use a spatial-temporal representation encoding the HR signals from multiple ROI volumes as its input. Then the spatial-temporal representations are fed into a convolutional network for HR estimation. We also take into account the relationship of adjacent HR measurements from a video sequence via Gated Recurrent Unit (GRU) and achieves efficient HR measurement. In addition, we build a large-scale multi-modal HR database (named as VIPL-HR, available at 'http://vipl.ict.ac.cn/view_database.php?id=15'), which contains 2,378 visible light videos (VIS) and 752 near-infrared (NIR) videos of 107 subjects. Our VIPL-HR database contains various variations such as head movements, illumination variations, and acquisition device changes, replicating a less-constrained scenario for HR estimation. The proposed approach outperforms the state-of-the-art methods on both the public-domain and our VIPL-HR databases.
Facial action units (AUs) recognition is essential for emotion analysis and has been widely applied in mental state analysis. Existing work on AU recognition usually requires big face dataset with AU labels; however, manual AU annotation requires expertise and can be time-consuming. In this work, we propose a semi-supervised approach for AU recognition utilizing a large number of web face images without AU labels and a relatively small face dataset with AU annotations inspired by the co-training methods. Unlike traditional co-training methods that require provided multi-view features and model re-training, we propose a novel co-training method, namely multi-label co-regularization, for semi-supervised facial AU recognition. Two deep neural networks are utilized to generate multi-view features for both labeled and unlabeled face images, and a multi-view loss is designed to enforce the two feature generators to get conditional independent representations. In order to constrain the prediction consistency of the two views, we further propose a multi-label co-regularization loss by minimizing the distance of the predicted AU probability distributions of two views. In addition, prior knowledge of the relationship between individual AUs is embedded through a graph convolutional network (GCN) for exploiting useful information from the big unlabeled dataset. Experiments on several benchmarks show that the proposed approach can effectively leverage large datasets of face images without AU labels to improve the AU recognition accuracy and outperform the state-of-the-art semi-supervised AU recognition methods.