Unsupervised Domain Adaptation for Vestibular Schwannoma and Cochlea Segmentation via Semi-supervised Learning and Label Fusion

Automatic methods to segment the vestibular schwannoma (VS) tumors and the cochlea from magnetic resonance imaging (MRI) are critical to VS treatment planning. Although supervised methods have achieved satisfactory performance in VS segmentation, they require full annotations by experts, which is laborious and time-consuming. In this work, we aim to tackle the VS and cochlea segmentation problem in an unsupervised domain adaptation setting. Our proposed method leverages both the image-level domain alignment to minimize the domain divergence and semi-supervised training to further boost the performance. Furthermore, we propose to fuse the labels predicted from multiple models via noisy label correction. In the MICCAI 2021 crossMoDA challenge, our results on the final evaluation leaderboard showed that our proposed method has achieved promising segmentation performance with mean dice score of 79.9% and 82.5% and ASSD of 1.29 mm and 0.18 mm for VS tumor and cochlea, respectively. The cochlea ASSD achieved by our method has outperformed all other competing methods as well as the supervised nnU-Net.

CrossMoDA 2021 challenge: Benchmark of Cross-Modality Domain Adaptation techniques for Vestibular Schwnannoma and Cochlea Segmentation

Domain Adaptation (DA) has recently raised strong interests in the medical imaging community. While a large variety of DA techniques has been proposed for image segmentation, most of these techniques have been validated either on private datasets or on small publicly available datasets. Moreover, these datasets mostly addressed single-class problems. To tackle these limitations, the Cross-Modality Domain Adaptation (crossMoDA) challenge was organised in conjunction with the 24th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2021). CrossMoDA is the first large and multi-class benchmark for unsupervised cross-modality DA. The challenge's goal is to segment two key brain structures involved in the follow-up and treatment planning of vestibular schwannoma (VS): the VS and the cochleas. Currently, the diagnosis and surveillance in patients with VS are performed using contrast-enhanced T1 (ceT1) MRI. However, there is growing interest in using non-contrast sequences such as high-resolution T2 (hrT2) MRI. Therefore, we created an unsupervised cross-modality segmentation benchmark. The training set provides annotated ceT1 (N=105) and unpaired non-annotated hrT2 (N=105). The aim was to automatically perform unilateral VS and bilateral cochlea segmentation on hrT2 as provided in the testing set (N=137). A total of 16 teams submitted their algorithm for the evaluation phase. The level of performance reached by the top-performing teams is strikingly high (best median Dice - VS:88.4%; Cochleas:85.7%) and close to full supervision (median Dice - VS:92.5%; Cochleas:87.7%). All top-performing methods made use of an image-to-image translation approach to transform the source-domain images into pseudo-target-domain images. A segmentation network was then trained using these generated images and the manual annotations provided for the source image.

A Survey on Epistemic (Model) Uncertainty in Supervised Learning: Recent Advances and Applications

Quantifying the uncertainty of supervised learning models plays an important role in making more reliable predictions. Epistemic uncertainty, which usually is due to insufficient knowledge about the model, can be reduced by collecting more data or refining the learning models. Over the last few years, scholars have proposed many epistemic uncertainty handling techniques which can be roughly grouped into two categories, i.e., Bayesian and ensemble. This paper provides a comprehensive review of epistemic uncertainty learning techniques in supervised learning over the last five years. As such, we, first, decompose the epistemic uncertainty into bias and variance terms. Then, a hierarchical categorization of epistemic uncertainty learning techniques along with their representative models is introduced. In addition, several applications such as computer vision (CV) and natural language processing (NLP) are presented, followed by a discussion on research gaps and possible future research directions.

An Explicit-Joint and Supervised-Contrastive Learning Framework for Few-Shot Intent Classification and Slot Filling

Intent classification (IC) and slot filling (SF) are critical building blocks in task-oriented dialogue systems. These two tasks are closely-related and can flourish each other. Since only a few utterances can be utilized for identifying fast-emerging new intents and slots, data scarcity issue often occurs when implementing IC and SF. However, few IC/SF models perform well when the number of training samples per class is quite small. In this paper, we propose a novel explicit-joint and supervised-contrastive learning framework for few-shot intent classification and slot filling. Its highlights are as follows. (i) The model extracts intent and slot representations via bidirectional interactions, and extends prototypical network to achieve explicit-joint learning, which guarantees that IC and SF tasks can mutually reinforce each other. (ii) The model integrates with supervised contrastive learning, which ensures that samples from same class are pulled together and samples from different classes are pushed apart. In addition, the model follows a not common but practical way to construct the episode, which gets rid of the traditional setting with fixed way and shot, and allows for unbalanced datasets. Extensive experiments on three public datasets show that our model can achieve promising performance.

Cross-Modality Domain Adaptation for Vestibular Schwannoma and Cochlea Segmentation

Automatic methods to segment the vestibular schwannoma (VS) tumors and the cochlea from magnetic resonance imaging (MRI) are critical to VS treatment planning. Although supervised methods have achieved satisfactory performance in VS segmentation, they require full annotations by experts, which is laborious and time-consuming. In this work, we aim to tackle the VS and cochlea segmentation problem in an unsupervised domain adaptation setting. Our proposed method leverages both the image-level domain alignment to minimize the domain divergence and semi-supervised training to further boost the performance. Furthermore, we propose to fuse the labels predicted from multiple models via noisy label correction. Our results on the challenge validation leaderboard showed that our unsupervised method has achieved promising VS and cochlea segmentation performance with mean dice score of 0.8261 $\pm$ 0.0416; The mean dice value for the tumor is 0.8302 $\pm$ 0.0772. This is comparable to the weakly-supervised based method.

Review Polarity-wise Recommender

Utilizing review information to enhance recommendation, the de facto review-involved recommender systems, have received increasing interests over the past few years. Thereinto, one advanced branch is to extract salient aspects from textual reviews (i.e., the item attributes that users express) and combine them with the matrix factorization technique. However, existing approaches all ignore the fact that semantically different reviews often include opposite aspect information. In particular, positive reviews usually express aspects that users prefer, while negative ones describe aspects that users reject. As a result, it may mislead the recommender systems into making incorrect decisions pertaining to user preference modeling. Towards this end, in this paper, we propose a Review Polarity-wise Recommender model, dubbed as RPR, to discriminately treat reviews with different polarities. To be specific, in this model, positive and negative reviews are separately gathered and utilized to model the user-preferred and user-rejected aspects, respectively. Besides, in order to overcome the imbalance problem of semantically different reviews, we also develop an aspect-aware importance weighting approach to align the aspect importance for these two kinds of reviews. Extensive experiments conducted on eight benchmark datasets have demonstrated the superiority of our model as compared to a series of state-of-the-art review-involved baselines. Moreover, our method can provide certain explanations to the real-world rating prediction scenarios.

Trade the Event: Corporate Events Detection for News-Based Event-Driven Trading

In this paper, we introduce an event-driven trading strategy that predicts stock movements by detecting corporate events from news articles. Unlike existing models that utilize textual features (e.g., bag-of-words) and sentiments to directly make stock predictions, we consider corporate events as the driving force behind stock movements and aim to profit from the temporary stock mispricing that may occur when corporate events take place. The core of the proposed strategy is a bi-level event detection model. The low-level event detector identifies events' existences from each token, while the high-level event detector incorporates the entire article's representation and the low-level detected results to discover events at the article-level. We also develop an elaborately-annotated dataset EDT for corporate event detection and news-based stock prediction benchmark. EDT includes 9721 news articles with token-level event labels as well as 303893 news articles with minute-level timestamps and comprehensive stock price labels. Experiments on EDT indicate that the proposed strategy outperforms all the baselines in winning rate, excess returns over the market, and the average return on each transaction.

Converse, Focus and Guess -- Towards Multi-Document Driven Dialogue

We propose a novel task, Multi-Document Driven Dialogue (MD3), in which an agent can guess the target document that the user is interested in by leading a dialogue. To benchmark progress, we introduce a new dataset of GuessMovie, which contains 16,881 documents, each describing a movie, and associated 13,434 dialogues. Further, we propose the MD3 model. Keeping guessing the target document in mind, it converses with the user conditioned on both document engagement and user feedback. In order to incorporate large-scale external documents into the dialogue, it pretrains a document representation which is sensitive to attributes it talks about an object. Then it tracks dialogue state by detecting evolvement of document belief and attribute belief, and finally optimizes dialogue policy in principle of entropy decreasing and reward increasing, which is expected to successfully guess the user's target in a minimum number of turns. Experiments show that our method significantly outperforms several strong baseline methods and is very close to human's performance.

Understanding the Effect of Out-of-distribution Examples and Interactive Explanations on Human-AI Decision Making

Although AI holds promise for improving human decision making in societally critical domains, it remains an open question how human-AI teams can reliably outperform AI alone and human alone in challenging prediction tasks (also known as complementary performance). We explore two directions to understand the gaps in achieving complementary performance. First, we argue that the typical experimental setup limits the potential of human-AI teams. To account for lower AI performance out-of-distribution than in-distribution because of distribution shift, we design experiments with different distribution types and investigate human performance for both in-distribution and out-of-distribution examples. Second, we develop novel interfaces to support interactive explanations so that humans can actively engage with AI assistance. Using in-person user study and large-scale randomized experiments across three tasks, we demonstrate a clear difference between in-distribution and out-of-distribution, and observe mixed results for interactive explanations: while interactive explanations improve human perception of AI assistance's usefulness, they may magnify human biases and lead to limited performance improvement. Overall, our work points out critical challenges and future directions towards complementary performance.