Responsible Deep Learning for Software as a Medical Device

Tools, models and statistical methods for signal processing and medical image analysis and training deep learning models to create research prototypes for eventual clinical applications are of special interest to the biomedical imaging community. But material and optical properties of biological tissues are complex and not easily captured by imaging devices. Added complexity can be introduced by datasets with underrepresentation of medical images from races and ethnicities for deep learning, and limited knowledge about the regulatory framework needed for commercialization and safety of emerging Artificial Intelligence (AI) and Machine Learning (ML) technologies for medical image analysis. This extended version of the workshop paper presented at the special session of the 2022 IEEE 19th International Symposium on Biomedical Imaging, describes strategy and opportunities by University of California professors engaged in machine learning (section I) and clinical research (section II), the Office of Science and Engineering Laboratories (OSEL) section III, and officials at the US FDA in Center for Devices & Radiological Health (CDRH) section IV. Performance evaluations of AI/ML models of skin (RGB), tissue biopsy (digital pathology), and lungs and kidneys (Magnetic Resonance, X-ray, Computed Tomography) medical images for regulatory evaluations and real-world deployment are discussed.

Integration and Performance Analysis of Artificial Intelligence and Computer Vision Based on Deep Learning Algorithms

This paper focuses on the analysis of the application effectiveness of the integration of deep learning and computer vision technologies. Deep learning achieves a historic breakthrough by constructing hierarchical neural networks, enabling end-to-end feature learning and semantic understanding of images. The successful experiences in the field of computer vision provide strong support for training deep learning algorithms. The tight integration of these two fields has given rise to a new generation of advanced computer vision systems, significantly surpassing traditional methods in tasks such as machine vision image classification and object detection. In this paper, typical image classification cases are combined to analyze the superior performance of deep neural network models while also pointing out their limitations in generalization and interpretability, proposing directions for future improvements. Overall, the efficient integration and development trend of deep learning with massive visual data will continue to drive technological breakthroughs and application expansion in the field of computer vision, making it possible to build truly intelligent machine vision systems. This deepening fusion paradigm will powerfully promote unprecedented tasks and functions in computer vision, providing stronger development momentum for related disciplines and industries.

Image Transformation for IoT Time-Series Data: A Review

In the era of the Internet of Things (IoT), where smartphones, built-in systems, wireless sensors, and nearly every smart device connect through local networks or the internet, billions of smart things communicate with each other and generate vast amounts of time-series data. As IoT time-series data is high-dimensional and high-frequency, time-series classification or regression has been a challenging issue in IoT. Recently, deep learning algorithms have demonstrated superior performance results in time-series data classification in many smart and intelligent IoT applications. However, it is hard to explore the hidden dynamic patterns and trends in time-series. Recent studies show that transforming IoT data into images improves the performance of the learning model. In this paper, we present a review of these studies which use image transformation/encoding techniques in IoT domain. We examine the studies according to their encoding techniques, data types, and application areas. Lastly, we emphasize the challenges and future dimensions of image transformation.

TOP-ReID: Multi-spectral Object Re-Identification with Token Permutation

Multi-spectral object Re-identification (ReID) aims to retrieve specific objects by leveraging complementary information from different image spectra. It delivers great advantages over traditional single-spectral ReID in complex visual environment. However, the significant distribution gap among different image spectra poses great challenges for effective multi-spectral feature representations. In addition, most of current Transformer-based ReID methods only utilize the global feature of class tokens to achieve the holistic retrieval, ignoring the local discriminative ones. To address the above issues, we step further to utilize all the tokens of Transformers and propose a cyclic token permutation framework for multi-spectral object ReID, dubbled TOP-ReID. More specifically, we first deploy a multi-stream deep network based on vision Transformers to preserve distinct information from different image spectra. Then, we propose a Token Permutation Module (TPM) for cyclic multi-spectral feature aggregation. It not only facilitates the spatial feature alignment across different image spectra, but also allows the class token of each spectrum to perceive the local details of other spectra. Meanwhile, we propose a Complementary Reconstruction Module (CRM), which introduces dense token-level reconstruction constraints to reduce the distribution gap across different image spectra. With the above modules, our proposed framework can generate more discriminative multi-spectral features for robust object ReID. Extensive experiments on three ReID benchmarks (i.e., RGBNT201, RGBNT100 and MSVR310) verify the effectiveness of our methods. The code is available at https://github.com/924973292/TOP-ReID.

Removing NSFW Concepts from Vision-and-Language Models for Text-to-Image Retrieval and Generation

Vision-and-Language models such as CLIP have demonstrated remarkable effectiveness across a wide range of tasks. However, these models are typically trained on web-scale data, which can introduce inappropriate content and lead to the development of unsafe and biased behavior. This, in turn, hampers their applicability in sensitive and trustworthy contexts and could raise significant concern in their adoption. To overcome these limitations, we introduce a methodology to make Vision-and-Language models safer by removing their sensitivity to not-safe-for-work concepts. We show how this can be done by distilling from a large language model which converts between safe and unsafe sentences and which is fine-tuned starting from just 100 manually-curated pairs. We conduct extensive experiments on the resulting embedding space for both retrieval and text-to-image generation, where we show that our model can also be properly employed with pre-trained image generators. Our source code and trained models are available at: https://github.com/aimagelab/safe-clip.

Camera calibration for the surround-view system: a benchmark and dataset

Surround-view system (SVS) is widely used in the Advanced Driver Assistance System (ADAS). SVS uses four fisheye lenses to monitor real-time scenes around the vehicle. However, accurate intrinsic and extrinsic parameter estimation is required for the proper functioning of the system. At present, the intrinsic calibration can be pipeline by utilizing checkerboard algorithm, while extrinsic calibration is still immature. Therefore, we proposed a specific calibration pipeline to estimate extrinsic parameters robustly. This scheme takes a driving sequence of four cameras as input. It firstly utilizes lane line to roughly estimate each camera pose. Considering the environmental condition differences in each camera, we separately select strategies from two methods to accurately estimate the extrinsic parameters. To achieve accurate estimates for both front and rear camera, we proposed a method that mutually iterating line detection and pose estimation. As for bilateral camera, we iteratively adjust the camera pose and position by minimizing texture and edge error between ground projections of adjacent cameras. After estimating the extrinsic parameters, the surround-view image can be synthesized by homography-based transformation. The proposed pipeline can robustly estimate the four SVS camera extrinsic parameters in real driving environments. In addition, to evaluate the proposed scheme, we build a surround-view fisheye dataset, which contains 40 videos with 32,000 frames, acquired from different real traffic scenarios. All the frames in each video are manually labeled with lane annotation, with its GT extrinsic parameters. Moreover, this surround-view dataset could be used by other researchers to evaluate their performance. The dataset will be available soon.

Domain Generalization with Vital Phase Augmentation

Deep neural networks have shown remarkable performance in image classification. However, their performance significantly deteriorates with corrupted input data. Domain generalization methods have been proposed to train robust models against out-of-distribution data. Data augmentation in the frequency domain is one of such approaches that enable a model to learn phase features to establish domain-invariant representations. This approach changes the amplitudes of the input data while preserving the phases. However, using fixed phases leads to susceptibility to phase fluctuations because amplitudes and phase fluctuations commonly occur in out-of-distribution. In this study, to address this problem, we introduce an approach using finite variation of the phases of input data rather than maintaining fixed phases. Based on the assumption that the degree of domain-invariant features varies for each phase, we propose a method to distinguish phases based on this degree. In addition, we propose a method called vital phase augmentation (VIPAug) that applies the variation to the phases differently according to the degree of domain-invariant features of given phases. The model depends more on the vital phases that contain more domain-invariant features for attaining robustness to amplitude and phase fluctuations. We present experimental evaluations of our proposed approach, which exhibited improved performance for both clean and corrupted data. VIPAug achieved SOTA performance on the benchmark CIFAR-10 and CIFAR-100 datasets, as well as near-SOTA performance on the ImageNet-100 and ImageNet datasets. Our code is available at https://github.com/excitedkid/vipaug.

Comparing YOLOv8 and Mask RCNN for object segmentation in complex orchard environments

Instance segmentation, an important image processing operation for automation in agriculture, is used to precisely delineate individual objects of interest within images, which provides foundational information for various automated or robotic tasks such as selective harvesting and precision pruning. This study compares the one-stage YOLOv8 and the two-stage Mask R-CNN machine learning models for instance segmentation under varying orchard conditions across two datasets. Dataset 1, collected in dormant season, includes images of dormant apple trees, which were used to train multi-object segmentation models delineating tree branches and trunks. Dataset 2, collected in the early growing season, includes images of apple tree canopies with green foliage and immature (green) apples (also called fruitlet), which were used to train single-object segmentation models delineating only immature green apples. The results showed that YOLOv8 performed better than Mask R-CNN, achieving good precision and near-perfect recall across both datasets at a confidence threshold of 0.5. Specifically, for Dataset 1, YOLOv8 achieved a precision of 0.90 and a recall of 0.95 for all classes. In comparison, Mask R-CNN demonstrated a precision of 0.81 and a recall of 0.81 for the same dataset. With Dataset 2, YOLOv8 achieved a precision of 0.93 and a recall of 0.97. Mask R-CNN, in this single-class scenario, achieved a precision of 0.85 and a recall of 0.88. Additionally, the inference times for YOLOv8 were 10.9 ms for multi-class segmentation (Dataset 1) and 7.8 ms for single-class segmentation (Dataset 2), compared to 15.6 ms and 12.8 ms achieved by Mask R-CNN's, respectively.

Scene Text Image Super-resolution based on Text-conditional Diffusion Models

Scene Text Image Super-resolution (STISR) has recently achieved great success as a preprocessing method for scene text recognition. STISR aims to transform blurred and noisy low-resolution (LR) text images in real-world settings into clear high-resolution (HR) text images suitable for scene text recognition. In this study, we leverage text-conditional diffusion models (DMs), known for their impressive text-to-image synthesis capabilities, for STISR tasks. Our experimental results revealed that text-conditional DMs notably surpass existing STISR methods. Especially when texts from LR text images are given as input, the text-conditional DMs are able to produce superior quality super-resolution text images. Utilizing this capability, we propose a novel framework for synthesizing LR-HR paired text image datasets. This framework consists of three specialized text-conditional DMs, each dedicated to text image synthesis, super-resolution, and image degradation. These three modules are vital for synthesizing distinct LR and HR paired images, which are more suitable for training STISR methods. Our experiments confirmed that these synthesized image pairs significantly enhance the performance of STISR methods in the TextZoom evaluation.

Generative AI Beyond LLMs: System Implications of Multi-Modal Generation

As the development of large-scale Generative AI models evolve beyond text (1D) generation to include image (2D) and video (3D) generation, processing spatial and temporal information presents unique challenges to quality, performance, and efficiency. We present the first work towards understanding this new system design space for multi-modal text-to-image (TTI) and text-to-video (TTV) generation models. Current model architecture designs are bifurcated into 2 categories: Diffusion- and Transformer-based models. Our systematic performance characterization on a suite of eight representative TTI/TTV models shows that after state-of-the-art optimization techniques such as Flash Attention are applied, Convolution accounts for up to 44% of execution time for Diffusion-based TTI models, while Linear layers consume up to 49% of execution time for Transformer-based models. We additionally observe that Diffusion-based TTI models resemble the Prefill stage of LLM inference, and benefit from 1.1-2.5x greater speedup from Flash Attention than Transformer-based TTI models that resemble the Decode phase. Since optimizations designed for LLMs do not map directly onto TTI/TTV models, we must conduct a thorough characterization of these workloads to gain insights for new optimization opportunities. In doing so, we define sequence length in the context of TTI/TTV models and observe sequence length can vary up to 4x in Diffusion model inference. We additionally observe temporal aspects of TTV workloads pose unique system bottlenecks, with Temporal Attention accounting for over 60% of total Attention time. Overall, our in-depth system performance characterization is a critical first step towards designing efficient and deployable systems for emerging TTI/TTV workloads.