LLM4Sweat: A Trustworthy Large Language Model for Hyperhidrosis Support

While large language models (LLMs) have shown promise in healthcare, their application for rare medical conditions is still hindered by scarce and unreliable datasets for fine-tuning. Hyperhidrosis, a disorder causing excessive sweating beyond physiological needs, is one such rare disorder, affecting 2-3% of the population and significantly impacting both physical comfort and psychosocial well-being. To date, no work has tailored LLMs to advance the diagnosis or care of hyperhidrosis. To address this gap, we present LLM4Sweat, an open-source and domain-specific LLM framework for trustworthy and empathetic hyperhidrosis support. The system follows a three-stage pipeline. In the data augmentation stage, a frontier LLM generates medically plausible synthetic vignettes from curated open-source data to create a diverse and balanced question-answer dataset. In the fine-tuning stage, an open-source foundation model is fine-tuned on the dataset to provide diagnosis, personalized treatment recommendations, and empathetic psychological support. In the inference and expert evaluation stage, clinical and psychological specialists assess accuracy, appropriateness, and empathy, with validated responses iteratively enriching the dataset. Experiments show that LLM4Sweat outperforms baselines and delivers the first open-source LLM framework for hyperhidrosis, offering a generalizable approach for other rare diseases with similar data and trustworthiness challenges.

Retrieval-Augmented Review Generation for Poisoning Recommender Systems

Recent studies have shown that recommender systems (RSs) are highly vulnerable to data poisoning attacks, where malicious actors inject fake user profiles, including a group of well-designed fake ratings, to manipulate recommendations. Due to security and privacy constraints in practice, attackers typically possess limited knowledge of the victim system and thus need to craft profiles that have transferability across black-box RSs. To maximize the attack impact, the profiles often remains imperceptible. However, generating such high-quality profiles with the restricted resources is challenging. Some works suggest incorporating fake textual reviews to strengthen the profiles; yet, the poor quality of the reviews largely undermines the attack effectiveness and imperceptibility under the practical setting. To tackle the above challenges, in this paper, we propose to enhance the quality of the review text by harnessing in-context learning (ICL) capabilities of multimodal foundation models. To this end, we introduce a demonstration retrieval algorithm and a text style transfer strategy to augment the navie ICL. Specifically, we propose a novel practical attack framework named RAGAN to generate high-quality fake user profiles, which can gain insights into the robustness of RSs. The profiles are generated by a jailbreaker and collaboratively optimized on an instructional agent and a guardian to improve the attack transferability and imperceptibility. Comprehensive experiments on various real-world datasets demonstrate that RAGAN achieves the state-of-the-art poisoning attack performance.

Large Foundation Model for Ads Recommendation

Online advertising relies on accurate recommendation models, with recent advances using pre-trained large-scale foundation models (LFMs) to capture users' general interests across multiple scenarios and tasks. However, existing methods have critical limitations: they extract and transfer only user representations (URs), ignoring valuable item representations (IRs) and user-item cross representations (CRs); and they simply use a UR as a feature in downstream applications, which fails to bridge upstream-downstream gaps and overlooks more transfer granularities. In this paper, we propose LFM4Ads, an All-Representation Multi-Granularity transfer framework for ads recommendation. It first comprehensively transfers URs, IRs, and CRs, i.e., all available representations in the pre-trained foundation model. To effectively utilize the CRs, it identifies the optimal extraction layer and aggregates them into transferable coarse-grained forms. Furthermore, we enhance the transferability via multi-granularity mechanisms: non-linear adapters for feature-level transfer, an Isomorphic Interaction Module for module-level transfer, and Standalone Retrieval for model-level transfer. LFM4Ads has been successfully deployed in Tencent's industrial-scale advertising platform, processing tens of billions of daily samples while maintaining terabyte-scale model parameters with billions of sparse embedding keys across approximately two thousand features. Since its production deployment in Q4 2024, LFM4Ads has achieved 10+ successful production launches across various advertising scenarios, including primary ones like Weixin Moments and Channels. These launches achieve an overall GMV lift of 2.45% across the entire platform, translating to estimated annual revenue increases in the hundreds of millions of dollars.

Distribution-Guided Auto-Encoder for User Multimodal Interest Cross Fusion

Traditional recommendation methods rely on correlating the embedding vectors of item IDs to capture implicit collaborative filtering signals to model the user's interest in the target item. Consequently, traditional ID-based methods often encounter data sparsity problems stemming from the sparse nature of ID features. To alleviate the problem of item ID sparsity, recommendation models incorporate multimodal item information to enhance recommendation accuracy. However, existing multimodal recommendation methods typically employ early fusion approaches, which focus primarily on combining text and image features, while neglecting the contextual influence of user behavior sequences. This oversight prevents dynamic adaptation of multimodal interest representations based on behavioral patterns, consequently restricting the model's capacity to effectively capture user multimodal interests. Therefore, this paper proposes the Distribution-Guided Multimodal-Interest Auto-Encoder (DMAE), which achieves the cross fusion of user multimodal interest at the behavioral level.Ultimately, extensive experiments demonstrate the superiority of DMAE.

MISS: Multi-Modal Tree Indexing and Searching with Lifelong Sequential Behavior for Retrieval Recommendation

Large-scale industrial recommendation systems typically employ a two-stage paradigm of retrieval and ranking to handle huge amounts of information. Recent research focuses on improving the performance of retrieval model. A promising way is to introduce extensive information about users and items. On one hand, lifelong sequential behavior is valuable. Existing lifelong behavior modeling methods in ranking stage focus on the interaction of lifelong behavior and candidate items from retrieval stage. In retrieval stage, it is difficult to utilize lifelong behavior because of a large corpus of candidate items. On the other hand, existing retrieval methods mostly relay on interaction information, potentially disregarding valuable multi-modal information. To solve these problems, we represent the pioneering exploration of leveraging multi-modal information and lifelong sequence model within the advanced tree-based retrieval model. We propose Multi-modal Indexing and Searching with lifelong Sequence (MISS), which contains a multi-modal index tree and a multi-modal lifelong sequence modeling module. Specifically, for better index structure, we propose multi-modal index tree, which is built using the multi-modal embedding to precisely represent item similarity. To precisely capture diverse user interests in user lifelong sequence, we propose collaborative general search unit (Co-GSU) and multi-modal general search unit (MM-GSU) for multi-perspective interests searching.

DGenCTR: Towards a Universal Generative Paradigm for Click-Through Rate Prediction via Discrete Diffusion

Recent advances in generative models have inspired the field of recommender systems to explore generative approaches, but most existing research focuses on sequence generation, a paradigm ill-suited for click-through rate (CTR) prediction. CTR models critically depend on a large number of cross-features between the target item and the user to estimate the probability of clicking on the item, and discarding these cross-features will significantly impair model performance. Therefore, to harness the ability of generative models to understand data distributions and thereby alleviate the constraints of traditional discriminative models in label-scarce space, diverging from the item-generation paradigm of sequence generation methods, we propose a novel sample-level generation paradigm specifically designed for the CTR task: a two-stage Discrete Diffusion-Based Generative CTR training framework (DGenCTR). This two-stage framework comprises a diffusion-based generative pre-training stage and a CTR-targeted supervised fine-tuning stage for CTR. Finally, extensive offline experiments and online A/B testing conclusively validate the effectiveness of our framework.

You Only Evaluate Once: A Tree-based Rerank Method at Meituan

Reranking plays a crucial role in modern recommender systems by capturing the mutual influences within the list. Due to the inherent challenges of combinatorial search spaces, most methods adopt a two-stage search paradigm: a simple General Search Unit (GSU) efficiently reduces the candidate space, and an Exact Search Unit (ESU) effectively selects the optimal sequence. These methods essentially involve making trade-offs between effectiveness and efficiency, while suffering from a severe \textbf{inconsistency problem}, that is, the GSU often misses high-value lists from ESU. To address this problem, we propose YOLOR, a one-stage reranking method that removes the GSU while retaining only the ESU. Specifically, YOLOR includes: (1) a Tree-based Context Extraction Module (TCEM) that hierarchically aggregates multi-scale contextual features to achieve "list-level effectiveness", and (2) a Context Cache Module (CCM) that enables efficient feature reuse across candidate permutations to achieve "permutation-level efficiency". Extensive experiments across public and industry datasets validate YOLOR's performance, and we have successfully deployed YOLOR on the Meituan food delivery platform.

OneLoc: Geo-Aware Generative Recommender Systems for Local Life Service

Local life service is a vital scenario in Kuaishou App, where video recommendation is intrinsically linked with store's location information. Thus, recommendation in our scenario is challenging because we should take into account user's interest and real-time location at the same time. In the face of such complex scenarios, end-to-end generative recommendation has emerged as a new paradigm, such as OneRec in the short video scenario, OneSug in the search scenario, and EGA in the advertising scenario. However, in local life service, an end-to-end generative recommendation model has not yet been developed as there are some key challenges to be solved. The first challenge is how to make full use of geographic information. The second challenge is how to balance multiple objectives, including user interests, the distance between user and stores, and some other business objectives. To address the challenges, we propose OneLoc. Specifically, we leverage geographic information from different perspectives: (1) geo-aware semantic ID incorporates both video and geographic information for tokenization, (2) geo-aware self-attention in the encoder leverages both video location similarity and user's real-time location, and (3) neighbor-aware prompt captures rich context information surrounding users for generation. To balance multiple objectives, we use reinforcement learning and propose two reward functions, i.e., geographic reward and GMV reward. With the above design, OneLoc achieves outstanding offline and online performance. In fact, OneLoc has been deployed in local life service of Kuaishou App. It serves 400 million active users daily, achieving 21.016% and 17.891% improvements in terms of gross merchandise value (GMV) and orders numbers.

Cohort-Aware Agents for Individualized Lung Cancer Risk Prediction Using a Retrieval-Augmented Model Selection Framework

Accurate lung cancer risk prediction remains challenging due to substantial variability across patient populations and clinical settings -- no single model performs best for all cohorts. To address this, we propose a personalized lung cancer risk prediction agent that dynamically selects the most appropriate model for each patient by combining cohort-specific knowledge with modern retrieval and reasoning techniques. Given a patient's CT scan and structured metadata -- including demographic, clinical, and nodule-level features -- the agent first performs cohort retrieval using FAISS-based similarity search across nine diverse real-world cohorts to identify the most relevant patient population from a multi-institutional database. Second, a Large Language Model (LLM) is prompted with the retrieved cohort and its associated performance metrics to recommend the optimal prediction algorithm from a pool of eight representative models, including classical linear risk models (e.g., Mayo, Brock), temporally-aware models (e.g., TDVIT, DLSTM), and multi-modal computer vision-based approaches (e.g., Liao, Sybil, DLS, DLI). This two-stage agent pipeline -- retrieval via FAISS and reasoning via LLM -- enables dynamic, cohort-aware risk prediction personalized to each patient's profile. Building on this architecture, the agent supports flexible and cohort-driven model selection across diverse clinical populations, offering a practical path toward individualized risk assessment in real-world lung cancer screening.

Global-Distribution Aware Scenario-Specific Variational Representation Learning Framework

With the emergence of e-commerce, the recommendations provided by commercial platforms must adapt to diverse scenarios to accommodate users' varying shopping preferences. Current methods typically use a unified framework to offer personalized recommendations for different scenarios. However, they often employ shared bottom representations, which partially hinders the model's capacity to capture scenario uniqueness. Ideally, users and items should exhibit specific characteristics in different scenarios, prompting the need to learn scenario-specific representations to differentiate scenarios. Yet, variations in user and item interactions across scenarios lead to data sparsity issues, impeding the acquisition of scenario-specific representations. To learn robust scenario-specific representations, we introduce a Global-Distribution Aware Scenario-Specific Variational Representation Learning Framework (GSVR) that can be directly applied to existing multi-scenario methods. Specifically, considering the uncertainty stemming from limited samples, our approach employs a probabilistic model to generate scenario-specific distributions for each user and item in each scenario, estimated through variational inference (VI). Additionally, we introduce the global knowledge-aware multinomial distributions as prior knowledge to regulate the learning of the posterior user and item distributions, ensuring similarities among distributions for users with akin interests and items with similar side information. This mitigates the risk of users or items with fewer records being overwhelmed in sparse scenarios. Extensive experimental results affirm the efficacy of GSVR in assisting existing multi-scenario recommendation methods in learning more robust representations.