MicroSegNet: A Deep Learning Approach for Prostate Segmentation on Micro-Ultrasound Images

Micro-ultrasound (micro-US) is a novel 29-MHz ultrasound technique that provides 3-4 times higher resolution than traditional ultrasound, delivering comparable accuracy for diagnosing prostate cancer to MRI but at a lower cost. Accurate prostate segmentation is crucial for prostate volume measurement, cancer diagnosis, prostate biopsy, and treatment planning. This paper proposes a deep learning approach for automated, fast, and accurate prostate segmentation on micro-US images. Prostate segmentation on micro-US is challenging due to artifacts and indistinct borders between the prostate, bladder, and urethra in the midline. We introduce MicroSegNet, a multi-scale annotation-guided Transformer UNet model to address this challenge. During the training process, MicroSegNet focuses more on regions that are hard to segment (challenging regions), where expert and non-expert annotations show discrepancies. We achieve this by proposing an annotation-guided cross entropy loss that assigns larger weight to pixels in hard regions and lower weight to pixels in easy regions. We trained our model using micro-US images from 55 patients, followed by evaluation on 20 patients. Our MicroSegNet model achieved a Dice coefficient of 0.942 and a Hausdorff distance of 2.11 mm, outperforming several state-of-the-art segmentation methods, as well as three human annotators with different experience levels. We will make our code and dataset publicly available to promote transparency and collaboration in research.

Image Registration of In Vivo Micro-Ultrasound and Ex Vivo Pseudo-Whole Mount Histopathology Images of the Prostate: A Proof-of-Concept Study

Early diagnosis of prostate cancer significantly improves a patient's 5-year survival rate. Biopsy of small prostate cancers is improved with image-guided biopsy. MRI-ultrasound fusion-guided biopsy is sensitive to smaller tumors but is underutilized due to the high cost of MRI and fusion equipment. Micro-ultrasound (micro-US), a novel high-resolution ultrasound technology, provides a cost-effective alternative to MRI while delivering comparable diagnostic accuracy. However, the interpretation of micro-US is challenging due to subtle gray scale changes indicating cancer vs normal tissue. This challenge can be addressed by training urologists with a large dataset of micro-US images containing the ground truth cancer outlines. Such a dataset can be mapped from surgical specimens (histopathology) onto micro-US images via image registration. In this paper, we present a semi-automated pipeline for registering in vivo micro-US images with ex vivo whole-mount histopathology images. Our pipeline begins with the reconstruction of pseudo-whole-mount histopathology images and a 3D micro-US volume. Each pseudo-whole-mount histopathology image is then registered with the corresponding axial micro-US slice using a two-stage approach that estimates an affine transformation followed by a deformable transformation. We evaluated our registration pipeline using micro-US and histopathology images from 18 patients who underwent radical prostatectomy. The results showed a Dice coefficient of 0.94 and a landmark error of 2.7 mm, indicating the accuracy of our registration pipeline. This proof-of-concept study demonstrates the feasibility of accurately aligning micro-US and histopathology images. To promote transparency and collaboration in research, we will make our code and dataset publicly available.

ImSimCSE: Improving Contrastive Learning for Sentence Embeddings from Two Perspectives

This paper aims to improve contrastive learning for sentence embeddings from two perspectives: handling dropout noise and addressing feature corruption. Specifically, for the first perspective, we identify that the dropout noise from negative pairs affects the model's performance. Therefore, we propose a simple yet effective method to deal with such type of noise. Secondly, we pinpoint the rank bottleneck of current solutions to feature corruption and propose a dimension-wise contrastive learning objective to address this issue. Both proposed methods are generic and can be applied to any contrastive learning based models for sentence embeddings. Experimental results on standard benchmarks demonstrate that combining both proposed methods leads to a gain of 1.8 points compared to the strong baseline SimCSE configured with BERT base. Furthermore, applying the proposed method to DiffCSE, another strong contrastive learning based baseline, results in a gain of 1.4 points.

Self-Supervised Sentence Compression for Meeting Summarization

The conventional summarization model often fails to capture critical information in meeting transcripts, as meeting corpus usually involves multiple parties with lengthy conversations and is stuffed with redundant and trivial content. To tackle this problem, we present SVB, an effective and efficient framework for meeting summarization that `compress' the redundancy while preserving important content via three processes: sliding-window dialogue restoration and \textbf{S}coring, channel-wise importance score \textbf{V}oting, and relative positional \textbf{B}ucketing. Specifically, under the self-supervised paradigm, the sliding-window scoring aims to rate the importance of each token from multiple views. Then these ratings are aggregated by channel-wise voting. Tokens with high ratings will be regarded as salient information and labeled as \textit{anchors}. Finally, to tailor the lengthy input to an acceptable length for the language model, the relative positional bucketing algorithm is performed to retain the anchors while compressing other irrelevant contents in different granularities. Without large-scale pre-training or expert-grade annotating tools, our proposed method outperforms previous state-of-the-art approaches. A vast amount of evaluations and analyses are conducted to prove the effectiveness of our method.

Message Passing Neural Networks for Traffic Forecasting

A road network, in the context of traffic forecasting, is typically modeled as a graph where the nodes are sensors that measure traffic metrics (such as speed) at that location. Traffic forecasting is interesting because it is complex as the future speed of a road is dependent on a number of different factors. Therefore, to properly forecast traffic, we need a model that is capable of capturing all these different factors. A factor that is missing from the existing works is the node interactions factor. Existing works fail to capture the inter-node interactions because none are using the message-passing flavor of GNN, which is the one best suited to capture the node interactions This paper presents a plausible scenario in road traffic where node interactions are important and argued that the most appropriate GNN flavor to capture node interactions is message-passing. Results from real-world data show the superiority of the message-passing flavor for traffic forecasting. An additional experiment using synthetic data shows that the message-passing flavor can capture inter-node interaction better than other flavors.

Traffic Forecasting on New Roads Unseen in the Training Data Using Spatial Contrastive Pre-Training

New roads are being constructed all the time. However, the capabilities of previous deep forecasting models to generalize to new roads not seen in the training data (unseen roads) are rarely explored. In this paper, we introduce a novel setup called a spatio-temporal (ST) split to evaluate the models' capabilities to generalize to unseen roads. In this setup, the models are trained on data from a sample of roads, but tested on roads not seen in the training data. Moreover, we also present a novel framework called Spatial Contrastive Pre-Training (SCPT) where we introduce a spatial encoder module to extract latent features from unseen roads during inference time. This spatial encoder is pre-trained using contrastive learning. During inference, the spatial encoder only requires two days of traffic data on the new roads and does not require any re-training. We also show that the output from the spatial encoder can be used effectively to infer latent node embeddings on unseen roads during inference time. The SCPT framework also incorporates a new layer, named the spatially gated addition (SGA) layer, to effectively combine the latent features from the output of the spatial encoder to existing backbones. Additionally, since there is limited data on the unseen roads, we argue that it is better to decouple traffic signals to trivial-to-capture periodic signals and difficult-to-capture Markovian signals, and for the spatial encoder to only learn the Markovian signals. Finally, we empirically evaluated SCPT using the ST split setup on four real-world datasets. The results showed that adding SCPT to a backbone consistently improves forecasting performance on unseen roads. More importantly, the improvements are greater when forecasting further into the future.

CANet: Curved Guide Line Network with Adaptive Decoder for Lane Detection

Lane detection is challenging due to the complicated on road scenarios and line deformation from different camera perspectives. Lots of solutions were proposed, but can not deal with corner lanes well. To address this problem, this paper proposes a new top-down deep learning lane detection approach, CANET. A lane instance is first responded by the heat-map on the U-shaped curved guide line at global semantic level, thus the corresponding features of each lane are aggregated at the response point. Then CANET obtains the heat-map response of the entire lane through conditional convolution, and finally decodes the point set to describe lanes via adaptive decoder. The experimental results show that CANET reaches SOTA in different metrics. Our code will be released soon.

Because Every Sensor Is Unique, so Is Every Pair: Handling Dynamicity in Traffic Forecasting

Traffic forecasting is a critical task to extract values from cyber-physical infrastructures, which is the backbone of smart transportation. However owing to external contexts, the dynamics at each sensor are unique. For example, the afternoon peaks at sensors near schools are more likely to occur earlier than those near residential areas. In this paper, we first analyze real-world traffic data to show that each sensor has a unique dynamic. Further analysis also shows that each pair of sensors also has a unique dynamic. Then, we explore how node embedding learns the unique dynamics at every sensor location. Next, we propose a novel module called Spatial Graph Transformers (SGT) where we use node embedding to leverage the self-attention mechanism to ensure that the information flow between two sensors is adaptive with respect to the unique dynamic of each pair. Finally, we present Graph Self-attention WaveNet (G-SWaN) to address the complex, non-linear spatiotemporal traffic dynamics. Through empirical experiments on four real-world, open datasets, we show that the proposed method achieves superior performance on both traffic speed and flow forecasting. Code is available at: https://github.com/aprbw/G-SWaN

CLARE: Conservative Model-Based Reward Learning for Offline Inverse Reinforcement Learning

This work aims to tackle a major challenge in offline Inverse Reinforcement Learning (IRL), namely the reward extrapolation error, where the learned reward function may fail to explain the task correctly and misguide the agent in unseen environments due to the intrinsic covariate shift. Leveraging both expert data and lower-quality diverse data, we devise a principled algorithm (namely CLARE) that solves offline IRL efficiently via integrating "conservatism" into a learned reward function and utilizing an estimated dynamics model. Our theoretical analysis provides an upper bound on the return gap between the learned policy and the expert policy, based on which we characterize the impact of covariate shift by examining subtle two-tier tradeoffs between the exploitation (on both expert and diverse data) and exploration (on the estimated dynamics model). We show that CLARE can provably alleviate the reward extrapolation error by striking the right exploitation-exploration balance therein. Extensive experiments corroborate the significant performance gains of CLARE over existing state-of-the-art algorithms on MuJoCo continuous control tasks (especially with a small offline dataset), and the learned reward is highly instructive for further learning.