Conditional Diffusion for 3D CT Volume Reconstruction from 2D X-rays

Computed tomography (CT) provides rich 3D anatomical details but is often constrained by high radiation exposure, substantial costs, and limited availability. While standard chest X-rays are cost-effective and widely accessible, they only provide 2D projections with limited pathological information. Reconstructing 3D CT volumes from 2D X-rays offers a transformative solution to increase diagnostic accessibility, yet existing methods predominantly rely on synthetic X-ray projections, limiting clinical generalization. In this work, we propose AXON, a multi-stage diffusion-based framework that reconstructs high-fidelity 3D CT volumes directly from real X-rays. AXON employs a coarse-to-fine strategy, with a Brownian Bridge diffusion model-based initial stage for global structural synthesis, followed by a ControlNet-based refinement stage for local intensity optimization. It also supports bi-planar X-ray input to mitigate depth ambiguities inherent in 2D-to-3D reconstruction. A super-resolution network is integrated to upscale the generated volumes to achieve diagnostic-grade resolution. Evaluations on both public and external datasets demonstrate that AXON significantly outperforms state-of-the-art baselines, achieving a 11.9% improvement in PSNR and a 11.0% increase in SSIM with robust generalizability across disparate clinical distributions. Our code is available at https://github.com/ai-med/AXON.

Controllable Complex Human Motion Video Generation via Text-to-Skeleton Cascades

Generating videos of complex human motions such as flips, cartwheels, and martial arts remains challenging for current video diffusion models. Text-only conditioning is temporally ambiguous for fine-grained motion control, while explicit pose-based controls, though effective, require users to provide complete skeleton sequences that are costly to produce for long and dynamic actions. We propose a two-stage cascaded framework that addresses both limitations. First, an autoregressive text-to-skeleton model generates 2D pose sequences from natural language descriptions by predicting each joint conditioned on previously generated poses. This design captures long-range temporal dependencies and inter-joint coordination required for complex motions. Second, a pose-conditioned video diffusion model synthesizes videos from a reference image and the generated skeleton sequence. It employs DINO-ALF (Adaptive Layer Fusion), a multi-level reference encoder that preserves appearance and clothing details under large pose changes and self-occlusions. To address the lack of publicly available datasets for complex human motion video generation, we introduce a Blender-based synthetic dataset containing 2,000 videos with diverse characters performing acrobatic and stunt-like motions. The dataset provides full control over appearance, motion, and environment. It fills an important gap because existing benchmarks significantly under-represent acrobatic motions while web-collected datasets raise copyright and privacy concerns. Experiments on our synthetic dataset and the Motion-X Fitness benchmark show that our text-to-skeleton model outperforms prior methods on FID, R-precision, and motion diversity. Our pose-to-video model also achieves the best results among all compared methods on VBench metrics for temporal consistency, motion smoothness, and subject preservation.

USFetal: Tools for Fetal Brain Ultrasound Compounding

Ultrasound offers a safe, cost-effective, and widely accessible technology for fetal brain imaging, making it especially suitable for routine clinical use. However, it suffers from view-dependent artifacts, operator variability, and a limited field of view, which make interpretation and quantitative evaluation challenging. Ultrasound compounding aims to overcome these limitations by integrating complementary information from multiple 3D acquisitions into a single, coherent volumetric representation. This work provides four main contributions: (1) We present the first systematic categorization of computational strategies for fetal brain ultrasound compounding, including both classical techniques and modern learning-based frameworks. (2) We implement and compare representative methods across four key categories - multi-scale, transformation-based, variational, and deep learning approaches - emphasizing their core principles and practical advantages. (3) Motivated by the lack of full-view, artifact-free ground truth required for supervised learning, we focus on unsupervised and self-supervised strategies and introduce two new deep learning based approaches: a self-supervised compounding framework and an adaptation of unsupervised deep plug-and-play priors for compounding. (4) We conduct a comprehensive evaluation on ten multi-view fetal brain ultrasound datasets, using both expert radiologist scoring and standard quantitative image-quality metrics. We also release the USFetal Compounding Toolbox, publicly available to support benchmarking and future research. Keywords: Ultrasound compounding, fetal brain, deep learning, self-supervised, unsupervised.

LatentMove: Towards Complex Human Movement Video Generation

Image-to-video (I2V) generation seeks to produce realistic motion sequences from a single reference image. Although recent methods exhibit strong temporal consistency, they often struggle when dealing with complex, non-repetitive human movements, leading to unnatural deformations. To tackle this issue, we present LatentMove, a DiT-based framework specifically tailored for highly dynamic human animation. Our architecture incorporates a conditional control branch and learnable face/body tokens to preserve consistency as well as fine-grained details across frames. We introduce Complex-Human-Videos (CHV), a dataset featuring diverse, challenging human motions designed to benchmark the robustness of I2V systems. We also introduce two metrics to assess the flow and silhouette consistency of generated videos with their ground truth. Experimental results indicate that LatentMove substantially improves human animation quality--particularly when handling rapid, intricate movements--thereby pushing the boundaries of I2V generation. The code, the CHV dataset, and the evaluation metrics will be available at https://github.com/ --.

MedBridge: Bridging Foundation Vision-Language Models to Medical Image Diagnosis

Recent vision-language foundation models deliver state-of-the-art results on natural image classification but falter on medical images due to pronounced domain shifts. At the same time, training a medical foundation model requires substantial resources, including extensive annotated data and high computational capacity. To bridge this gap with minimal overhead, we introduce MedBridge, a lightweight multimodal adaptation framework that re-purposes pretrained VLMs for accurate medical image diagnosis. MedBridge comprises three key components. First, a Focal Sampling module that extracts high-resolution local regions to capture subtle pathological features and compensate for the limited input resolution of general-purpose VLMs. Second, a Query Encoder (QEncoder) injects a small set of learnable queries that attend to the frozen feature maps of VLM, aligning them with medical semantics without retraining the entire backbone. Third, a Mixture of Experts mechanism, driven by learnable queries, harnesses the complementary strength of diverse VLMs to maximize diagnostic performance. We evaluate MedBridge on five medical imaging benchmarks across three key adaptation tasks, demonstrating its superior performance in both cross-domain and in-domain adaptation settings, even under varying levels of training data availability. Notably, MedBridge achieved over 6-15% improvement in AUC compared to state-of-the-art VLM adaptation methods in multi-label thoracic disease diagnosis, underscoring its effectiveness in leveraging foundation models for accurate and data-efficient medical diagnosis. Our code is available at https://github.com/ai-med/MedBridge.

DiaMond: Dementia Diagnosis with Multi-Modal Vision Transformers Using MRI and PET

Diagnosing dementia, particularly for Alzheimer's Disease (AD) and frontotemporal dementia (FTD), is complex due to overlapping symptoms. While magnetic resonance imaging (MRI) and positron emission tomography (PET) data are critical for the diagnosis, integrating these modalities in deep learning faces challenges, often resulting in suboptimal performance compared to using single modalities. Moreover, the potential of multi-modal approaches in differential diagnosis, which holds significant clinical importance, remains largely unexplored. We propose a novel framework, DiaMond, to address these issues with vision Transformers to effectively integrate MRI and PET. DiaMond is equipped with self-attention and a novel bi-attention mechanism that synergistically combine MRI and PET, alongside a multi-modal normalization to reduce redundant dependency, thereby boosting the performance. DiaMond significantly outperforms existing multi-modal methods across various datasets, achieving a balanced accuracy of 92.4% in AD diagnosis, 65.2% for AD-MCI-CN classification, and 76.5% in differential diagnosis of AD and FTD. We also validated the robustness of DiaMond in a comprehensive ablation study. The code is available at https://github.com/ai-med/DiaMond.

Faster Image2Video Generation: A Closer Look at CLIP Image Embedding's Impact on Spatio-Temporal Cross-Attentions

This paper investigates the role of CLIP image embeddings within the Stable Video Diffusion (SVD) framework, focusing on their impact on video generation quality and computational efficiency. Our findings indicate that CLIP embeddings, while crucial for aesthetic quality, do not significantly contribute towards the subject and background consistency of video outputs. Moreover, the computationally expensive cross-attention mechanism can be effectively replaced by a simpler linear layer. This layer is computed only once at the first diffusion inference step, and its output is then cached and reused throughout the inference process, thereby enhancing efficiency while maintaining high-quality outputs. Building on these insights, we introduce the VCUT, a training-free approach optimized for efficiency within the SVD architecture. VCUT eliminates temporal cross-attention and replaces spatial cross-attention with a one-time computed linear layer, significantly reducing computational load. The implementation of VCUT leads to a reduction of up to 322T Multiple-Accumulate Operations (MACs) per video and a decrease in model parameters by up to 50M, achieving a 20% reduction in latency compared to the baseline. Our approach demonstrates that conditioning during the Semantic Binding stage is sufficient, eliminating the need for continuous computation across all inference steps and setting a new standard for efficient video generation.

Mamba? Catch The Hype Or Rethink What Really Helps for Image Registration

Our findings indicate that adopting "advanced" computational elements fails to significantly improve registration accuracy. Instead, well-established registration-specific designs offer fair improvements, enhancing results by a marginal 1.5\% over the baseline. Our findings emphasize the importance of rigorous, unbiased evaluation and contribution disentanglement of all low- and high-level registration components, rather than simply following the computer vision trends with "more advanced" computational blocks. We advocate for simpler yet effective solutions and novel evaluation metrics that go beyond conventional registration accuracy, warranting further research across diverse organs and modalities. The code is available at \url{https://github.com/BailiangJ/rethink-reg}.

Stable-Pose: Leveraging Transformers for Pose-Guided Text-to-Image Generation

Controllable text-to-image (T2I) diffusion models have shown impressive performance in generating high-quality visual content through the incorporation of various conditions. Current methods, however, exhibit limited performance when guided by skeleton human poses, especially in complex pose conditions such as side or rear perspectives of human figures. To address this issue, we present Stable-Pose, a novel adapter model that introduces a coarse-to-fine attention masking strategy into a vision Transformer (ViT) to gain accurate pose guidance for T2I models. Stable-Pose is designed to adeptly handle pose conditions within pre-trained Stable Diffusion, providing a refined and efficient way of aligning pose representation during image synthesis. We leverage the query-key self-attention mechanism of ViTs to explore the interconnections among different anatomical parts in human pose skeletons. Masked pose images are used to smoothly refine the attention maps based on target pose-related features in a hierarchical manner, transitioning from coarse to fine levels. Additionally, our loss function is formulated to allocate increased emphasis to the pose region, thereby augmenting the model's precision in capturing intricate pose details. We assessed the performance of Stable-Pose across five public datasets under a wide range of indoor and outdoor human pose scenarios. Stable-Pose achieved an AP score of 57.1 in the LAION-Human dataset, marking around 13% improvement over the established technique ControlNet. The project link and code is available at https://github.com/ai-med/StablePose.

Box It to Bind It: Unified Layout Control and Attribute Binding in T2I Diffusion Models

While latent diffusion models (LDMs) excel at creating imaginative images, they often lack precision in semantic fidelity and spatial control over where objects are generated. To address these deficiencies, we introduce the Box-it-to-Bind-it (B2B) module - a novel, training-free approach for improving spatial control and semantic accuracy in text-to-image (T2I) diffusion models. B2B targets three key challenges in T2I: catastrophic neglect, attribute binding, and layout guidance. The process encompasses two main steps: i) Object generation, which adjusts the latent encoding to guarantee object generation and directs it within specified bounding boxes, and ii) attribute binding, guaranteeing that generated objects adhere to their specified attributes in the prompt. B2B is designed as a compatible plug-and-play module for existing T2I models, markedly enhancing model performance in addressing the key challenges. We evaluate our technique using the established CompBench and TIFA score benchmarks, demonstrating significant performance improvements compared to existing methods. The source code will be made publicly available at https://github.com/nextaistudio/BoxIt2BindIt.