Intracranial hemorrhage (ICH) is a pathological condition characterized by bleeding inside the skull or brain, which can be attributed to various factors. Identifying, localizing and quantifying ICH has important clinical implications, in a bleed-dependent manner. While deep learning techniques are widely used in medical image segmentation and have been applied to the ICH segmentation task, existing public ICH datasets do not support the multi-class segmentation problem. To address this, we develop the Brain Hemorrhage Segmentation Dataset (BHSD), which provides a 3D multi-class ICH dataset containing 192 volumes with pixel-level annotations and 2200 volumes with slice-level annotations across five categories of ICH. To demonstrate the utility of the dataset, we formulate a series of supervised and semi-supervised ICH segmentation tasks. We provide experimental results with state-of-the-art models as reference benchmarks for further model developments and evaluations on this dataset.
Consistency regularization has been widely studied in recent semi-supervised semantic segmentation methods. Remarkable performance has been achieved, benefiting from image, feature, and network perturbations. To make full use of these perturbations, in this work, we propose a new consistency regularization framework called mutual knowledge distillation (MKD). We innovatively introduce two auxiliary mean-teacher models based on the consistency regularization method. More specifically, we use the pseudo label generated by one mean teacher to supervise the other student network to achieve a mutual knowledge distillation between two branches. In addition to using image-level strong and weak augmentation, we also employ feature augmentation considering implicit semantic distributions to add further perturbations to the students. The proposed framework significantly increases the diversity of the training samples. Extensive experiments on public benchmarks show that our framework outperforms previous state-of-the-art(SOTA) methods under various semi-supervised settings. Code is available at: https://github.com/jianlong-yuan/semi-mmseg.