R2P: A Deep Learning Model from mmWave Radar to Point Cloud

Recent research has shown the effectiveness of mmWave radar sensing for object detection in low visibility environments, which makes it an ideal technique in autonomous navigation systems. In this paper, we introduce Radar to Point Cloud (R2P), a deep learning model that generates smooth, dense, and highly accurate point cloud representation of a 3D object with fine geometry details, based on rough and sparse point clouds with incorrect points obtained from mmWave radar. These input point clouds are converted from the 2D depth images that are generated from raw mmWave radar sensor data, characterized by inconsistency, and orientation and shape errors. R2P utilizes an architecture of two sequential deep learning encoder-decoder blocks to extract the essential features of those radar-based input point clouds of an object when observed from multiple viewpoints, and to ensure the internal consistency of a generated output point cloud and its accurate and detailed shape reconstruction of the original object. We implement R2P to replace Stage 2 of our recently proposed 3DRIMR (3D Reconstruction and Imaging via mmWave Radar) system. Our experiments demonstrate the significant performance improvement of R2P over the popular existing methods such as PointNet, PCN, and the original 3DRIMR design.

Dual-CLVSA: a Novel Deep Learning Approach to Predict Financial Markets with Sentiment Measurements

It is a challenging task to predict financial markets. The complexity of this task is mainly due to the interaction between financial markets and market participants, who are not able to keep rational all the time, and often affected by emotions such as fear and ecstasy. Based on the state-of-the-art approach particularly for financial market predictions, a hybrid convolutional LSTM Based variational sequence-to-sequence model with attention (CLVSA), we propose a novel deep learning approach, named dual-CLVSA, to predict financial market movement with both trading data and the corresponding social sentiment measurements, each through a separate sequence-to-sequence channel. We evaluate the performance of our approach with backtesting on historical trading data of SPDR SP 500 Trust ETF over eight years. The experiment results show that dual-CLVSA can effectively fuse the two types of data, and verify that sentiment measurements are not only informative for financial market predictions, but they also contain extra profitable features to boost the performance of our predicting system.

A Knowledge-Based Decision Support System for In Vitro Fertilization Treatment

In Vitro Fertilization (IVF) is the most widely used Assisted Reproductive Technology (ART). IVF usually involves controlled ovarian stimulation, oocyte retrieval, fertilization in the laboratory with subsequent embryo transfer. The first two steps correspond with follicular phase of females and ovulation in their menstrual cycle. Therefore, we refer to it as the treatment cycle in our paper. The treatment cycle is crucial because the stimulation medications in IVF treatment are applied directly on patients. In order to optimize the stimulation effects and lower the side effects of the stimulation medications, prompt treatment adjustments are in need. In addition, the quality and quantity of the retrieved oocytes have a significant effect on the outcome of the following procedures. To improve the IVF success rate, we propose a knowledge-based decision support system that can provide medical advice on the treatment protocol and medication adjustment for each patient visit during IVF treatment cycle. Our system is efficient in data processing and light-weighted which can be easily embedded into electronic medical record systems. Moreover, an oocyte retrieval oriented evaluation demonstrates that our system performs well in terms of accuracy of advice for the protocols and medications.

DeepPoint: A Deep Learning Model for 3D Reconstruction in Point Clouds via mmWave Radar

Recent research has shown that mmWave radar sensing is effective for object detection in low visibility environments, which makes it an ideal technique in autonomous navigation systems such as autonomous vehicles. However, due to the characteristics of radar signals such as sparsity, low resolution, specularity, and high noise, it is still quite challenging to reconstruct 3D object shapes via mmWave radar sensing. Built on our recent proposed 3DRIMR (3D Reconstruction and Imaging via mmWave Radar), we introduce in this paper DeepPoint, a deep learning model that generates 3D objects in point cloud format that significantly outperforms the original 3DRIMR design. The model adopts a conditional Generative Adversarial Network (GAN) based deep neural network architecture. It takes as input the 2D depth images of an object generated by 3DRIMR's Stage 1, and outputs smooth and dense 3D point clouds of the object. The model consists of a novel generator network that utilizes a sequence of DeepPoint blocks or layers to extract essential features of the union of multiple rough and sparse input point clouds of an object when observed from various viewpoints, given that those input point clouds may contain many incorrect points due to the imperfect generation process of 3DRIMR's Stage 1. The design of DeepPoint adopts a deep structure to capture the global features of input point clouds, and it relies on an optimally chosen number of DeepPoint blocks and skip connections to achieve performance improvement over the original 3DRIMR design. Our experiments have demonstrated that this model significantly outperforms the original 3DRIMR and other standard techniques in reconstructing 3D objects.

CLVSA: A Convolutional LSTM Based Variational Sequence-to-Sequence Model with Attention for Predicting Trends of Financial Markets

Financial markets are a complex dynamical system. The complexity comes from the interaction between a market and its participants, in other words, the integrated outcome of activities of the entire participants determines the markets trend, while the markets trend affects activities of participants. These interwoven interactions make financial markets keep evolving. Inspired by stochastic recurrent models that successfully capture variability observed in natural sequential data such as speech and video, we propose CLVSA, a hybrid model that consists of stochastic recurrent networks, the sequence-to-sequence architecture, the self- and inter-attention mechanism, and convolutional LSTM units to capture variationally underlying features in raw financial trading data. Our model outperforms basic models, such as convolutional neural network, vanilla LSTM network, and sequence-to-sequence model with attention, based on backtesting results of six futures from January 2010 to December 2017. Our experimental results show that, by introducing an approximate posterior, CLVSA takes advantage of an extra regularizer based on the Kullback-Leibler divergence to prevent itself from overfitting traps.

Financial Markets Prediction with Deep Learning

Financial markets are difficult to predict due to its complex systems dynamics. Although there have been some recent studies that use machine learning techniques for financial markets prediction, they do not offer satisfactory performance on financial returns. We propose a novel one-dimensional convolutional neural networks (CNN) model to predict financial market movement. The customized one-dimensional convolutional layers scan financial trading data through time, while different types of data, such as prices and volume, share parameters (kernels) with each other. Our model automatically extracts features instead of using traditional technical indicators and thus can avoid biases caused by selection of technical indicators and pre-defined coefficients in technical indicators. We evaluate the performance of our prediction model with strictly backtesting on historical trading data of six futures from January 2010 to October 2017. The experiment results show that our CNN model can effectively extract more generalized and informative features than traditional technical indicators, and achieves more robust and profitable financial performance than previous machine learning approaches.

Colorectal Polyp Detection in Real-world Scenario: Design and Experiment Study

Colorectal polyps are abnormal tissues growing on the intima of the colon or rectum with a high risk of developing into colorectal cancer, the third leading cause of cancer death worldwide. Early detection and removal of colon polyps via colonoscopy have proved to be an effective approach to prevent colorectal cancer. Recently, various CNN-based computer-aided systems have been developed to help physicians detect polyps. However, these systems do not perform well in real-world colonoscopy operations due to the significant difference between images in a real colonoscopy and those in the public datasets. Unlike the well-chosen clear images with obvious polyps in the public datasets, images from a colonoscopy are often blurry and contain various artifacts such as fluid, debris, bubbles, reflection, specularity, contrast, saturation, and medical instruments, with a wide variety of polyps of different sizes, shapes, and textures. All these factors pose a significant challenge to effective polyp detection in a colonoscopy. To this end, we collect a private dataset that contains 7,313 images from 224 complete colonoscopy procedures. This dataset represents realistic operation scenarios and thus can be used to better train the models and evaluate a system's performance in practice. We propose an integrated system architecture to address the unique challenges for polyp detection. Extensive experiments results show that our system can effectively detect polyps in a colonoscopy with excellent performance in real time.

Retinopathy of Prematurity Stage Diagnosis Using Object Segmentation and Convolutional Neural Networks

Retinopathy of Prematurity (ROP) is an eye disorder primarily affecting premature infants with lower weights. It causes proliferation of vessels in the retina and could result in vision loss and, eventually, retinal detachment, leading to blindness. While human experts can easily identify severe stages of ROP, the diagnosis of earlier stages, which are the most relevant to determining treatment choice, are much more affected by variability in subjective interpretations of human experts. In recent years, there has been a significant effort to automate the diagnosis using deep learning. This paper builds upon the success of previous models and develops a novel architecture, which combines object segmentation and convolutional neural networks (CNN) to construct an effective classifier of ROP stages 1-3 based on neonatal retinal images. Motivated by the fact that the formation and shape of a demarcation line in the retina is the distinguishing feature between earlier ROP stages, our proposed system first trains an object segmentation model to identify the demarcation line at a pixel level and adds the resulting mask as an additional "color" channel in the original image. Then, the system trains a CNN classifier based on the processed images to leverage information from both the original image and the mask, which helps direct the model's attention to the demarcation line. In a number of careful experiments comparing its performance to previous object segmentation systems and CNN-only systems trained on our dataset, our novel architecture significantly outperforms previous systems in accuracy, demonstrating the effectiveness of our proposed pipeline.

Pseudo-Labeling for Small Lesion Detection on Diabetic Retinopathy Images

Diabetic retinopathy (DR) is a primary cause of blindness in working-age people worldwide. About 3 to 4 million people with diabetes become blind because of DR every year. Diagnosis of DR through color fundus images is a common approach to mitigate such problem. However, DR diagnosis is a difficult and time consuming task, which requires experienced clinicians to identify the presence and significance of many small features on high resolution images. Convolutional Neural Network (CNN) has proved to be a promising approach for automatic biomedical image analysis recently. In this work, we investigate lesion detection on DR fundus images with CNN-based object detection methods. Lesion detection on fundus images faces two unique challenges. The first one is that our dataset is not fully labeled, i.e., only a subset of all lesion instances are marked. Not only will these unlabeled lesion instances not contribute to the training of the model, but also they will be mistakenly counted as false negatives, leading the model move to the opposite direction. The second challenge is that the lesion instances are usually very small, making them difficult to be found by normal object detectors. To address the first challenge, we introduce an iterative training algorithm for the semi-supervised method of pseudo-labeling, in which a considerable number of unlabeled lesion instances can be discovered to boost the performance of the lesion detector. For the small size targets problem, we extend both the input size and the depth of feature pyramid network (FPN) to produce a large CNN feature map, which can preserve the detail of small lesions and thus enhance the effectiveness of the lesion detector. The experimental results show that our proposed methods significantly outperform the baselines.

3D Aggregated Faster R-CNN for General Lesion Detection

Lesions are damages and abnormalities in tissues of the human body. Many of them can later turn into fatal diseases such as cancers. Detecting lesions are of great importance for early diagnosis and timely treatment. To this end, Computed Tomography (CT) scans often serve as the screening tool, allowing us to leverage the modern object detection techniques to detect the lesions. However, lesions in CT scans are often small and sparse. The local area of lesions can be very confusing, leading the region based classifier branch of Faster R-CNN easily fail. Therefore, most of the existing state-of-the-art solutions train two types of heterogeneous networks (multi-phase) separately for the candidate generation and the False Positive Reduction (FPR) purposes. In this paper, we enforce an end-to-end 3D Aggregated Faster R-CNN solution by stacking an "aggregated classifier branch" on the backbone of RPN. This classifier branch is equipped with Feature Aggregation and Local Magnification Layers to enhance the classifier branch. We demonstrate our model can achieve the state of the art performance on both LUNA16 and DeepLesion dataset. Especially, we achieve the best single-model FROC performance on LUNA16 with the inference time being 4.2s per processed scan.