A bag of tricks for real-time Mitotic Figure detection

Mitotic figure (MF) detection in histopathology images is challenging due to large variations in slide scanners, staining protocols, tissue types, and the presence of artifacts. This paper presents a collection of training techniques - a bag of tricks - that enable robust, real-time MF detection across diverse domains. We build on the efficient RTMDet single stage object detector to achieve high inference speed suitable for clinical deployment. Our method addresses scanner variability and tumor heterogeneity via extensive multi-domain training data, balanced sampling, and careful augmentation. Additionally, we employ targeted, hard negative mining on necrotic and debris tissue to reduce false positives. In a grouped 5-fold cross-validation across multiple MF datasets, our model achieves an F1 score between 0.78 and 0.84. On the preliminary test set of the MItosis DOmain Generalization (MIDOG) 2025 challenge, our single-stage RTMDet-S based approach reaches an F1 of 0.81, outperforming larger models and demonstrating adaptability to new, unfamiliar domains. The proposed solution offers a practical trade-off between accuracy and speed, making it attractive for real-world clinical adoption.

UltraTac: Integrated Ultrasound-Augmented Visuotactile Sensor for Enhanced Robotic Perception

Visuotactile sensors provide high-resolution tactile information but are incapable of perceiving the material features of objects. We present UltraTac, an integrated sensor that combines visuotactile imaging with ultrasound sensing through a coaxial optoacoustic architecture. The design shares structural components and achieves consistent sensing regions for both modalities. Additionally, we incorporate acoustic matching into the traditional visuotactile sensor structure, enabling integration of the ultrasound sensing modality without compromising visuotactile performance. Through tactile feedback, we dynamically adjust the operating state of the ultrasound module to achieve flexible functional coordination. Systematic experiments demonstrate three key capabilities: proximity sensing in the 3-8 cm range ($R^2=0.90$), material classification (average accuracy: 99.20%), and texture-material dual-mode object recognition achieving 92.11% accuracy on a 15-class task. Finally, we integrate the sensor into a robotic manipulation system to concurrently detect container surface patterns and internal content, which verifies its potential for advanced human-machine interaction and precise robotic manipulation.

From Leiden to Pleasure Island: The Constant Potts Model for Community Detection as a Hedonic Game

Community detection is one of the fundamental problems in data science which consists of partitioning nodes into disjoint communities. We present a game-theoretic perspective on the Constant Potts Model (CPM) for partitioning networks into disjoint communities, emphasizing its efficiency, robustness, and accuracy. Efficiency: We reinterpret CPM as a potential hedonic game by decomposing its global Hamiltonian into local utility functions, where the local utility gain of each agent matches the corresponding increase in global utility. Leveraging this equivalence, we prove that local optimization of the CPM objective via better-response dynamics converges in pseudo-polynomial time to an equilibrium partition. Robustness: We introduce and relate two stability criteria: a strict criterion based on a novel notion of robustness, requiring nodes to simultaneously maximize neighbors and minimize non-neighbors within communities, and a relaxed utility function based on a weighted sum of these objectives, controlled by a resolution parameter. Accuracy: In community tracking scenarios, where initial partitions are used to bootstrap the Leiden algorithm with partial ground-truth information, our experiments reveal that robust partitions yield higher accuracy in recovering ground-truth communities.

Decomposing Behavioral Phase Transitions in LLMs: Order Parameters for Emergent Misalignment

Fine-tuning LLMs on narrowly harmful datasets can lead to behavior that is broadly misaligned with respect to human values. To understand when and how this emergent misalignment occurs, we develop a comprehensive framework for detecting and characterizing rapid transitions during fine-tuning using both distributional change detection methods as well as order parameters that are formulated in plain English and evaluated by an LLM judge. Using an objective statistical dissimilarity measure, we quantify how the phase transition that occurs during fine-tuning affects multiple aspects of the model. In particular, we assess what percentage of the total distributional change in model outputs is captured by different aspects, such as alignment or verbosity, providing a decomposition of the overall transition. We also find that the actual behavioral transition occurs later in training than indicated by the peak in the gradient norm alone. Our framework enables the automated discovery and quantification of language-based order parameters, which we demonstrate on examples ranging from knowledge questions to politics and ethics.

Unobtrusive In-Situ Measurement of Behavior Change by Deep Metric Similarity Learning of Motion Patterns

This paper introduces an unobtrusive in-situ measurement method to detect user behavior changes during arbitrary exposures in XR systems. Here, such behavior changes are typically associated with the Proteus effect or bodily affordances elicited by different avatars that the users embody in XR. We present a biometric user model based on deep metric similarity learning, which uses high-dimensional embeddings as reference vectors to identify behavior changes of individual users. We evaluate our model against two alternative approaches: a (non-learned) motion analysis based on central tendencies of movement patterns and subjective post-exposure embodiment questionnaires frequently used in various XR exposures. In a within-subject study, participants performed a fruit collection task while embodying avatars of different body heights (short, actual-height, and tall). Subjective assessments confirmed the effective manipulation of perceived body schema, while the (non-learned) objective analyses of head and hand movements revealed significant differences across conditions. Our similarity learning model trained on the motion data successfully identified the elicited behavior change for various query and reference data pairings of the avatar conditions. The approach has several advantages in comparison to existing methods: 1) In-situ measurement without additional user input, 2) generalizable and scalable motion analysis for various use cases, 3) user-specific analysis on the individual level, and 4) with a trained model, users can be added and evaluated in real time to study how avatar changes affect behavior.

Activation Subspaces for Out-of-Distribution Detection

To ensure the reliability of deep models in real-world applications, out-of-distribution (OOD) detection methods aim to distinguish samples close to the training distribution (in-distribution, ID) from those farther away (OOD). In this work, we propose a novel OOD detection method that utilizes singular value decomposition of the weight matrix of the classification head to decompose the model's activations into decisive and insignificant components, which contribute maximally, respectively minimally, to the final classifier output. We find that the subspace of insignificant components more effectively distinguishes ID from OOD data than raw activations in regimes of large distribution shifts (Far-OOD). This occurs because the classification objective leaves the insignificant subspace largely unaffected, yielding features that are ''untainted'' by the target classification task. Conversely, in regimes of smaller distribution shifts (Near-OOD), we find that activation shaping methods profit from only considering the decisive subspace, as the insignificant component can cause interference in the activation space. By combining two findings into a single approach, termed ActSub, we achieve state-of-the-art results in various standard OOD benchmarks.

Automated Clinical Problem Detection from SOAP Notes using a Collaborative Multi-Agent LLM Architecture

Accurate interpretation of clinical narratives is critical for patient care, but the complexity of these notes makes automation challenging. While Large Language Models (LLMs) show promise, single-model approaches can lack the robustness required for high-stakes clinical tasks. We introduce a collaborative multi-agent system (MAS) that models a clinical consultation team to address this gap. The system is tasked with identifying clinical problems by analyzing only the Subjective (S) and Objective (O) sections of SOAP notes, simulating the diagnostic reasoning process of synthesizing raw data into an assessment. A Manager agent orchestrates a dynamically assigned team of specialist agents who engage in a hierarchical, iterative debate to reach a consensus. We evaluated our MAS against a single-agent baseline on a curated dataset of 420 MIMIC-III notes. The dynamic multi-agent configuration demonstrated consistently improved performance in identifying congestive heart failure, acute kidney injury, and sepsis. Qualitative analysis of the agent debates reveals that this structure effectively surfaces and weighs conflicting evidence, though it can occasionally be susceptible to groupthink. By modeling a clinical team's reasoning process, our system offers a promising path toward more accurate, robust, and interpretable clinical decision support tools.

Continuous Monitoring of Large-Scale Generative AI via Deterministic Knowledge Graph Structures

Generative AI (GEN AI) models have revolutionized diverse application domains but present substantial challenges due to reliability concerns, including hallucinations, semantic drift, and inherent biases. These models typically operate as black-boxes, complicating transparent and objective evaluation. Current evaluation methods primarily depend on subjective human assessment, limiting scalability, transparency, and effectiveness. This research proposes a systematic methodology using deterministic and Large Language Model (LLM)-generated Knowledge Graphs (KGs) to continuously monitor and evaluate GEN AI reliability. We construct two parallel KGs: (i) a deterministic KG built using explicit rule-based methods, predefined ontologies, domain-specific dictionaries, and structured entity-relation extraction rules, and (ii) an LLM-generated KG dynamically derived from real-time textual data streams such as live news articles. Utilizing real-time news streams ensures authenticity, mitigates biases from repetitive training, and prevents adaptive LLMs from bypassing predefined benchmarks through feedback memorization. To quantify structural deviations and semantic discrepancies, we employ several established KG metrics, including Instantiated Class Ratio (ICR), Instantiated Property Ratio (IPR), and Class Instantiation (CI). An automated real-time monitoring framework continuously computes deviations between deterministic and LLM-generated KGs. By establishing dynamic anomaly thresholds based on historical structural metric distributions, our method proactively identifies and flags significant deviations, thus promptly detecting semantic anomalies or hallucinations. This structured, metric-driven comparison between deterministic and dynamically generated KGs delivers a robust and scalable evaluation framework.

JVLGS: Joint Vision-Language Gas Leak Segmentation

Gas leaks pose serious threats to human health and contribute significantly to atmospheric pollution, drawing increasing public concern. However, the lack of effective detection methods hampers timely and accurate identification of gas leaks. While some vision-based techniques leverage infrared videos for leak detection, the blurry and non-rigid nature of gas clouds often limits their effectiveness. To address these challenges, we propose a novel framework called Joint Vision-Language Gas leak Segmentation (JVLGS), which integrates the complementary strengths of visual and textual modalities to enhance gas leak representation and segmentation. Recognizing that gas leaks are sporadic and many video frames may contain no leak at all, our method incorporates a post-processing step to reduce false positives caused by noise and non-target objects, an issue that affects many existing approaches. Extensive experiments conducted across diverse scenarios show that JVLGS significantly outperforms state-of-the-art gas leak segmentation methods. We evaluate our model under both supervised and few-shot learning settings, and it consistently achieves strong performance in both, whereas competing methods tend to perform well in only one setting or poorly in both. Code available at: https://github.com/GeekEagle/JVLGS

Comprehensive Signal Quality Evaluation of a Wearable Textile ECG Garment: A Sex-Balanced Study

We introduce a novel wearable textile-garment featuring an innovative electrode placement aimed at minimizing noise and motion artifacts, thereby enhancing signal fidelity in Electrocardiography (ECG) recordings. We present a comprehensive, sex-balanced evaluation involving 15 healthy males and 15 healthy female participants to ensure the device's suitability across anatomical and physiological variations. The assessment framework encompasses distinct evaluation approaches: quantitative signal quality indices to objectively benchmark device performance; rhythm-based analyzes of physiological parameters such as heart rate and heart rate variability; machine learning classification tasks to assess application-relevant predictive utility; morphological analysis of ECG features including amplitude and interval parameters; and investigations of the effects of electrode projection angle given by the textile / body shape, with all analyzes stratified by sex to elucidate sex-specific influences. Evaluations were conducted across various activity phases representing real-world conditions. The results demonstrate that the textile system achieves signal quality highly concordant with reference devices in both rhythm and morphological analyses, exhibits robust classification performance, and enables identification of key sex-specific determinants affecting signal acquisition. These findings underscore the practical viability of textile-based ECG garments for physiological monitoring as well as psychophysiological state detection. Moreover, we identify the importance of incorporating sex-specific design considerations to ensure equitable and reliable cardiac diagnostics in wearable health technologies.