ISLES'24: Improving final infarct prediction in ischemic stroke using multimodal imaging and clinical data

Accurate estimation of core (irreversibly damaged tissue) and penumbra (salvageable tissue) volumes is essential for ischemic stroke treatment decisions. Perfusion CT, the clinical standard, estimates these volumes but is affected by variations in deconvolution algorithms, implementations, and thresholds. Core tissue expands over time, with growth rates influenced by thrombus location, collateral circulation, and inherent patient-specific factors. Understanding this tissue growth is crucial for determining the need to transfer patients to comprehensive stroke centers, predicting the benefits of additional reperfusion attempts during mechanical thrombectomy, and forecasting final clinical outcomes. This work presents the ISLES'24 challenge, which addresses final post-treatment stroke infarct prediction from pre-interventional acute stroke imaging and clinical data. ISLES'24 establishes a unique 360-degree setting where all feasibly accessible clinical data are available for participants, including full CT acute stroke imaging, sub-acute follow-up MRI, and clinical tabular data. The contributions of this work are two-fold: first, we introduce a standardized benchmarking of final stroke infarct segmentation algorithms through the ISLES'24 challenge; second, we provide insights into infarct segmentation using multimodal imaging and clinical data strategies by identifying outperforming methods on a finely curated dataset. The outputs of this challenge are anticipated to enhance clinical decision-making and improve patient outcome predictions. All ISLES'24 materials, including data, performance evaluation scripts, and leading algorithmic strategies, are available to the research community following \url{https://isles-24.grand-challenge.org/}.

Classification of 24-hour movement behaviors from wrist-worn accelerometer data: from handcrafted features to deep learning techniques

Purpose: We compared the performance of deep learning (DL) and classical machine learning (ML) algorithms for the classification of 24-hour movement behavior into sleep, sedentary, light intensity physical activity (LPA), and moderate-to-vigorous intensity physical activity (MVPA). Methods: Open-access data from 151 adults wearing a wrist-worn accelerometer (Axivity-AX3) was used. Participants were randomly divided into training, validation, and test sets (121, 15, and 15 participants each). Raw acceleration signals were segmented into non-overlapping 10-second windows, and then a total of 104 handcrafted features were extracted. Four DL algorithms-Long Short-Term Memory (LSTM), Bidirectional Long Short-Term Memory (BiLSTM), Gated Recurrent Units (GRU), and One-Dimensional Convolutional Neural Network (1D-CNN)-were trained using raw acceleration signals and with handcrafted features extracted from these signals to predict 24-hour movement behavior categories. The handcrafted features were also used to train classical ML algorithms, namely Random Forest (RF), Support Vector Machine (SVM), Extreme Gradient Boosting (XGBoost), Logistic Regression (LR), Artificial Neural Network (ANN), and Decision Tree (DT) for classifying 24-hour movement behavior intensities. Results: LSTM, BiLSTM, and GRU showed an overall accuracy of approximately 85% when trained with raw acceleration signals, and 1D-CNN an overall accuracy of approximately 80%. When trained on handcrafted features, the overall accuracy for both DL and classical ML algorithms ranged from 70% to 81%. Overall, there was a higher confusion in classification of MVPA and LPA, compared to sleep and sedentary categories. Conclusion: DL methods with raw acceleration signals had only slightly better performance in predicting 24-hour movement behavior intensities, compared to when DL and classical ML were trained with handcrafted features.

Vehicle 24-Color Long Tail Recognition Based on Smooth Modulation Neural Network with Multi-layer Feature Representation

Vehicle color recognition plays an important role in intelligent traffic management and criminal investigation assistance. However, the current vehicle color recognition research involves at most 13 types of colors and the recognition accuracy is low, which is difficult to meet practical applications. To this end, this paper has built a benchmark dataset (Vehicle Color-24) that includes 24 types of vehicle colors, including 10091 vehicle pictures taken from 100 hours of urban road surveillance videos. In addition, in order to solve the problem of long tail distribution in Vehicle Color-24 dataset and low recognition rate of existing methods, this paper proposes a Smooth Modulated Neural Network with Multi-layer Feature Representation (SMNN-MFR) is used for 24 types of vehicle color recognition. SMNN-MFR includes four parts: feature extraction, multi-scale feature fusion, suggestion frame generation and smooth modulation. The model is trained and verified on the Vehicle Color-24 benchmark dataset. Comprehensive experiments show that the average recognition accuracy of the algorithm in the 24 categories of color benchmark databases is 94.96%, which is 33.47% higher than the Faster RCNN network. In addition, the average accuracy rate of the model when recognizing 8 types of colors is 97.25%, and the detection accuracy of algorithms in similar databases is improved. At the same time, visualization and ablation experiments also proved the rationality of our network settings and the effectiveness of each module. The code and database are published at: https://github.com/mendy-2013.

AXOLOTL'24 Shared Task on Multilingual Explainable Semantic Change Modeling

This paper describes the organization and findings of AXOLOTL'24, the first multilingual explainable semantic change modeling shared task. We present new sense-annotated diachronic semantic change datasets for Finnish and Russian which were employed in the shared task, along with a surprise test-only German dataset borrowed from an existing source. The setup of AXOLOTL'24 is new to the semantic change modeling field, and involves subtasks of identifying unknown (novel) senses and providing dictionary-like definitions to these senses. The methods of the winning teams are described and compared, thus paving a path towards explainability in computational approaches to historical change of meaning.

How We Won the ISLES'24 Challenge by Preprocessing

Stroke is among the top three causes of death worldwide, and accurate identification of stroke lesion boundaries is critical for diagnosis and treatment. Supervised deep learning methods have emerged as the leading solution for stroke lesion segmentation but require large, diverse, and annotated datasets. The ISLES'24 challenge addresses this need by providing longitudinal stroke imaging data, including CT scans taken on arrival to the hospital and follow-up MRI taken 2-9 days from initial arrival, with annotations derived from follow-up MRI. Importantly, models submitted to the ISLES'24 challenge are evaluated using only CT inputs, requiring prediction of lesion progression that may not be visible in CT scans for segmentation. Our winning solution shows that a carefully designed preprocessing pipeline including deep-learning-based skull stripping and custom intensity windowing is beneficial for accurate segmentation. Combined with a standard large residual nnU-Net architecture for segmentation, this approach achieves a mean test Dice of 28.5 with a standard deviation of 21.27.

LLMs for energy and macronutrients estimation using only text data from 24-hour dietary recalls: a parameter-efficient fine-tuning experiment using a 10-shot prompt

BACKGROUND: Most artificial intelligence tools used to estimate nutritional content rely on image input. However, whether large language models (LLMs) can accurately predict nutritional values based solely on text descriptions of foods consumed remains unknown. If effective, this approach could enable simpler dietary monitoring without the need for photographs. METHODS: We used 24-hour dietary recalls from adolescents aged 12-19 years in the National Health and Nutrition Examination Survey (NHANES). An open-source quantized LLM was prompted using a 10-shot, chain-of-thought approach to estimate energy and five macronutrients based solely on text strings listing foods and their quantities. We then applied parameter-efficient fine-tuning (PEFT) to evaluate whether predictive accuracy improved. NHANES-calculated values served as the ground truth for energy, proteins, carbohydrates, total sugar, dietary fiber and total fat. RESULTS: In a pooled dataset of 11,281 adolescents (49.9% male, mean age 15.4 years), the vanilla LLM yielded poor predictions. The mean absolute error (MAE) was 652.08 for energy and the Lin's CCC <0.46 across endpoints. In contrast, the fine-tuned model performed substantially better, with energy MAEs ranging from 171.34 to 190.90 across subsets, and Lin's CCC exceeding 0.89 for all outcomes. CONCLUSIONS: When prompted using a chain-of-thought approach and fine-tuned with PEFT, open-source LLMs exposed solely to text input can accurately predict energy and macronutrient values from 24-hour dietary recalls. This approach holds promise for low-burden, text-based dietary monitoring tools.

Feature Selection on a Flare Forecasting Testbed: A Comparative Study of 24 Methods

The Space-Weather ANalytics for Solar Flares (SWAN-SF) is a multivariate time series benchmark dataset recently created to serve the heliophysics community as a testbed for solar flare forecasting models. SWAN-SF contains 54 unique features, with 24 quantitative features computed from the photospheric magnetic field maps of active regions, describing their precedent flare activity. In this study, for the first time, we systematically attacked the problem of quantifying the relevance of these features to the ambitious task of flare forecasting. We implemented an end-to-end pipeline for preprocessing, feature selection, and evaluation phases. We incorporated 24 Feature Subset Selection (FSS) algorithms, including multivariate and univariate, supervised and unsupervised, wrappers and filters. We methodologically compared the results of different FSS algorithms, both on the multivariate time series and vectorized formats, and tested their correlation and reliability, to the extent possible, by using the selected features for flare forecasting on unseen data, in univariate and multivariate fashions. We concluded our investigation with a report of the best FSS methods in terms of their top-k features, and the analysis of the findings. We wish the reproducibility of our study and the availability of the data allow the future attempts be comparable with our findings and themselves.

LLM+KG@VLDB'24 Workshop Summary

The unification of large language models (LLMs) and knowledge graphs (KGs) has emerged as a hot topic. At the LLM+KG'24 workshop, held in conjunction with VLDB 2024 in Guangzhou, China, one of the key themes explored was important data management challenges and opportunities due to the effective interaction between LLMs and KGs. This report outlines the major directions and approaches presented by various speakers during the LLM+KG'24 workshop.

Validation of a 24-hour-ahead Prediction model for a Residential Electrical Load under diverse climate

Accurate household electrical energy demand prediction is essential for effectively managing sustainable Energy Communities. Integrated with the Energy Management System, these communities aim to optimise operational costs. However, most existing forecasting models are region-specific and depend on large datasets, limiting their applicability across different climates and geographical areas. These models often lack flexibility and may not perform well in regions with limited historical data, leading to inaccurate predictions. This paper proposes a global model for 24-hour-ahead hourly electrical energy demand prediction that is designed to perform effectively across diverse climate conditions and datasets. The model's efficiency is demonstrated using data from two distinct regions: Ireland, with a maritime climate and Vietnam, with a tropical climate. Remarkably, the model achieves high accuracy even with a limited dataset spanning only nine months. Its robustness is further validated across different seasons in Ireland (summer and winter) and Vietnam (dry and wet). The proposed model is evaluated against state-of-the-art machine learning and deep learning methods. Simulation results indicate that the model consistently outperforms benchmark models, showcasing its capability to provide reliable forecasts globally, regardless of varying climatic conditions and data availability. This research underscores the model's potential to enhance the efficiency and sustainability of Energy Communities worldwide. The proposed model achieves a Mean Absolute Percentage Error of 8.0% and 4.0% on the full Irish and Vietnamese datasets.

RetiNerveNet: Using Recursive Deep Learning to Estimate Pointwise 24-2 Visual Field Data based on Retinal Structure

Glaucoma is the leading cause of irreversible blindness in the world, affecting over 70 million people. The cumbersome Standard Automated Perimetry (SAP) test is most frequently used to detect visual loss due to glaucoma. Due to the SAP test's innate difficulty and its high test-retest variability, we propose the RetiNerveNet, a deep convolutional recursive neural network for obtaining estimates of the SAP visual field. RetiNerveNet uses information from the more objective Spectral-Domain Optical Coherence Tomography (SDOCT). RetiNerveNet attempts to trace-back the arcuate convergence of the retinal nerve fibers, starting from the Retinal Nerve Fiber Layer (RNFL) thickness around the optic disc, to estimate individual age-corrected 24-2 SAP values. Recursive passes through the proposed network sequentially yield estimates of the visual locations progressively farther from the optic disc. The proposed network is able to obtain more accurate estimates of the individual visual field values, compared to a number of baselines, implying its utility as a proxy for SAP. We further augment RetiNerveNet to additionally predict the SAP Mean Deviation values and also create an ensemble of RetiNerveNets that further improves the performance, by increasingly weighting-up underrepresented parts of the training data.