Enhancing Radiological Diagnosis: A Collaborative Approach Integrating AI and Human Expertise for Visual Miss Correction

Human-AI collaboration to identify and correct perceptual errors in chest radiographs has not been previously explored. This study aimed to develop a collaborative AI system, CoRaX, which integrates eye gaze data and radiology reports to enhance diagnostic accuracy in chest radiology by pinpointing perceptual errors and refining the decision-making process. Using public datasets REFLACX and EGD-CXR, the study retrospectively developed CoRaX, employing a large multimodal model to analyze image embeddings, eye gaze data, and radiology reports. The system's effectiveness was evaluated based on its referral-making process, the quality of referrals, and performance in collaborative diagnostic settings. CoRaX was tested on a simulated error dataset of 271 samples with 28% (93 of 332) missed abnormalities. The system corrected 21% (71 of 332) of these errors, leaving 7% (22 of 312) unresolved. The Referral-Usefulness score, indicating the accuracy of predicted regions for all true referrals, was 0.63 (95% CI 0.59, 0.68). The Total-Usefulness score, reflecting the diagnostic accuracy of CoRaX's interactions with radiologists, showed that 84% (237 of 280) of these interactions had a score above 0.40. In conclusion, CoRaX efficiently collaborates with radiologists to address perceptual errors across various abnormalities, with potential applications in the education and training of novice radiologists.

Multimodal Learning and Cognitive Processes in Radiology: MedGaze for Chest X-ray Scanpath Prediction

Predicting human gaze behavior within computer vision is integral for developing interactive systems that can anticipate user attention, address fundamental questions in cognitive science, and hold implications for fields like human-computer interaction (HCI) and augmented/virtual reality (AR/VR) systems. Despite methodologies introduced for modeling human eye gaze behavior, applying these models to medical imaging for scanpath prediction remains unexplored. Our proposed system aims to predict eye gaze sequences from radiology reports and CXR images, potentially streamlining data collection and enhancing AI systems using larger datasets. However, predicting human scanpaths on medical images presents unique challenges due to the diverse nature of abnormal regions. Our model predicts fixation coordinates and durations critical for medical scanpath prediction, outperforming existing models in the computer vision community. Utilizing a two-stage training process and large publicly available datasets, our approach generates static heatmaps and eye gaze videos aligned with radiology reports, facilitating comprehensive analysis. We validate our approach by comparing its performance with state-of-the-art methods and assessing its generalizability among different radiologists, introducing novel strategies to model radiologists' search patterns during CXR image diagnosis. Based on the radiologist's evaluation, MedGaze can generate human-like gaze sequences with a high focus on relevant regions over the CXR images. It sometimes also outperforms humans in terms of redundancy and randomness in the scanpaths.

Global-to-local Expression-aware Embeddings for Facial Action Unit Detection

Expressions and facial action units (AUs) are two levels of facial behavior descriptors. Expression auxiliary information has been widely used to improve the AU detection performance. However, most existing expression representations can only describe pre-determined discrete categories (e.g., Angry, Disgust, Happy, Sad, etc.) and cannot capture subtle expression transformations like AUs. In this paper, we propose a novel fine-grained \textsl{Global Expression representation Encoder} to capture subtle and continuous facial movements, to promote AU detection. To obtain such a global expression representation, we propose to train an expression embedding model on a large-scale expression dataset according to global expression similarity. Moreover, considering the local definition of AUs, it is essential to extract local AU features. Therefore, we design a \textsl{Local AU Features Module} to generate local facial features for each AU. Specifically, it consists of an AU feature map extractor and a corresponding AU mask extractor. First, the two extractors transform the global expression representation into AU feature maps and masks, respectively. Then, AU feature maps and their corresponding AU masks are multiplied to generate AU masked features focusing on local facial region. Finally, the AU masked features are fed into an AU classifier for judging the AU occurrence. Extensive experiment results demonstrate the superiority of our proposed method. Our method validly outperforms previous works and achieves state-of-the-art performances on widely-used face datasets, including BP4D, DISFA, and BP4D+.

Facial Action Units Detection Aided by Global-Local Expression Embedding

Since Facial Action Unit (AU) annotations require domain expertise, common AU datasets only contain a limited number of subjects. As a result, a crucial challenge for AU detection is addressing identity overfitting. We find that AUs and facial expressions are highly associated, and existing facial expression datasets often contain a large number of identities. In this paper, we aim to utilize the expression datasets without AU labels to facilitate AU detection. Specifically, we develop a novel AU detection framework aided by the Global-Local facial Expressions Embedding, dubbed GLEE-Net. Our GLEE-Net consists of three branches to extract identity-independent expression features for AU detection. We introduce a global branch for modeling the overall facial expression while eliminating the impacts of identities. We also design a local branch focusing on specific local face regions. The combined output of global and local branches is firstly pre-trained on an expression dataset as an identity-independent expression embedding, and then finetuned on AU datasets. Therefore, we significantly alleviate the issue of limited identities. Furthermore, we introduce a 3D global branch that extracts expression coefficients through 3D face reconstruction to consolidate 2D AU descriptions. Finally, a Transformer-based multi-label classifier is employed to fuse all the representations for AU detection. Extensive experiments demonstrate that our method significantly outperforms the state-of-the-art on the widely-used DISFA, BP4D and BP4D+ datasets.