An objective validation of polyp and instrument segmentation methods in colonoscopy through Medico 2020 polyp segmentation and MedAI 2021 transparency challenges

Automatic analysis of colonoscopy images has been an active field of research motivated by the importance of early detection of precancerous polyps. However, detecting polyps during the live examination can be challenging due to various factors such as variation of skills and experience among the endoscopists, lack of attentiveness, and fatigue leading to a high polyp miss-rate. Deep learning has emerged as a promising solution to this challenge as it can assist endoscopists in detecting and classifying overlooked polyps and abnormalities in real time. In addition to the algorithm's accuracy, transparency and interpretability are crucial to explaining the whys and hows of the algorithm's prediction. Further, most algorithms are developed in private data, closed source, or proprietary software, and methods lack reproducibility. Therefore, to promote the development of efficient and transparent methods, we have organized the "Medico automatic polyp segmentation (Medico 2020)" and "MedAI: Transparency in Medical Image Segmentation (MedAI 2021)" competitions. We present a comprehensive summary and analyze each contribution, highlight the strength of the best-performing methods, and discuss the possibility of clinical translations of such methods into the clinic. For the transparency task, a multi-disciplinary team, including expert gastroenterologists, accessed each submission and evaluated the team based on open-source practices, failure case analysis, ablation studies, usability and understandability of evaluations to gain a deeper understanding of the models' credibility for clinical deployment. Through the comprehensive analysis of the challenge, we not only highlight the advancements in polyp and surgical instrument segmentation but also encourage qualitative evaluation for building more transparent and understandable AI-based colonoscopy systems.

Z-GMOT: Zero-shot Generic Multiple Object Tracking

Despite the significant progress made in recent years, Multi-Object Tracking (MOT) approaches still suffer from several limitations, including their reliance on prior knowledge of tracking targets, which necessitates the costly annotation of large labeled datasets. As a result, existing MOT methods are limited to a small set of predefined categories, and they struggle with unseen objects in the real world. To address these issues, Generic Multiple Object Tracking (GMOT) has been proposed, which requires less prior information about the targets. However, all existing GMOT approaches follow a one-shot paradigm, relying mainly on the initial bounding box and thus struggling to handle variants e.g., viewpoint, lighting, occlusion, scale, and etc. In this paper, we introduce a novel approach to address the limitations of existing MOT and GMOT methods. Specifically, we propose a zero-shot GMOT (Z-GMOT) algorithm that can track never-seen object categories with zero training examples, without the need for predefined categories or an initial bounding box. To achieve this, we propose iGLIP, an improved version of Grounded language-image pretraining (GLIP), which can detect unseen objects while minimizing false positives. We evaluate our Z-GMOT thoroughly on the GMOT-40 dataset, AnimalTrack testset, DanceTrack testset. The results of these evaluations demonstrate a significant improvement over existing methods. For instance, on the GMOT-40 dataset, the Z-GMOT outperforms one-shot GMOT with OC-SORT by 27.79 points HOTA and 44.37 points MOTA. On the AnimalTrack dataset, it surpasses fully-supervised methods with DeepSORT by 12.55 points HOTA and 8.97 points MOTA. To facilitate further research, we will make our code and models publicly available upon acceptance of this paper.

EmbryosFormer: Deformable Transformer and Collaborative Encoding-Decoding for Embryos Stage Development Classification

The timing of cell divisions in early embryos during the In-Vitro Fertilization (IVF) process is a key predictor of embryo viability. However, observing cell divisions in Time-Lapse Monitoring (TLM) is a time-consuming process and highly depends on experts. In this paper, we propose EmbryosFormer, a computational model to automatically detect and classify cell divisions from original time-lapse images. Our proposed network is designed as an encoder-decoder deformable transformer with collaborative heads. The transformer contracting path predicts per-image labels and is optimized by a classification head. The transformer expanding path models the temporal coherency between embryo images to ensure monotonic non-decreasing constraint and is optimized by a segmentation head. Both contracting and expanding paths are synergetically learned by a collaboration head. We have benchmarked our proposed EmbryosFormer on two datasets: a public dataset with mouse embryos with 8-cell stage and an in-house dataset with human embryos with 4-cell stage. Source code: https://github.com/UARK-AICV/Embryos.