FRAME: Feedback-Refined Agent Methodology for Enhancing Medical Research Insights

The automation of scientific research through large language models (LLMs) presents significant opportunities but faces critical challenges in knowledge synthesis and quality assurance. We introduce Feedback-Refined Agent Methodology (FRAME), a novel framework that enhances medical paper generation through iterative refinement and structured feedback. Our approach comprises three key innovations: (1) A structured dataset construction method that decomposes 4,287 medical papers into essential research components through iterative refinement; (2) A tripartite architecture integrating Generator, Evaluator, and Reflector agents that progressively improve content quality through metric-driven feedback; and (3) A comprehensive evaluation framework that combines statistical metrics with human-grounded benchmarks. Experimental results demonstrate FRAME's effectiveness, achieving significant improvements over conventional approaches across multiple models (9.91% average gain with DeepSeek V3, comparable improvements with GPT-4o Mini) and evaluation dimensions. Human evaluation confirms that FRAME-generated papers achieve quality comparable to human-authored works, with particular strength in synthesizing future research directions. The results demonstrated our work could efficiently assist medical research by building a robust foundation for automated medical research paper generation while maintaining rigorous academic standards.

IIMedGPT: Promoting Large Language Model Capabilities of Medical Tasks by Efficient Human Preference Alignment

Recent researches of large language models(LLM), which is pre-trained on massive general-purpose corpora, have achieved breakthroughs in responding human queries. However, these methods face challenges including limited data insufficiency to support extensive pre-training and can not align responses with users' instructions. To address these issues, we introduce a medical instruction dataset, CMedINS, containing six medical instructions derived from actual medical tasks, which effectively fine-tunes LLM in conjunction with other data. Subsequently, We launch our medical model, IIMedGPT, employing an efficient preference alignment method, Direct preference Optimization(DPO). The results show that our final model outperforms existing medical models in medical dialogue.Datsets, Code and model checkpoints will be released upon acceptance.

Beyond Training: Dynamic Token Merging for Zero-Shot Video Understanding

Recent advancements in multimodal large language models (MLLMs) have opened new avenues for video understanding. However, achieving high fidelity in zero-shot video tasks remains challenging. Traditional video processing methods rely heavily on fine-tuning to capture nuanced spatial-temporal details, which incurs significant data and computation costs. In contrast, training-free approaches, though efficient, often lack robustness in preserving context-rich features across complex video content. To this end, we propose DYTO, a novel dynamic token merging framework for zero-shot video understanding that adaptively optimizes token efficiency while preserving crucial scene details. DYTO integrates a hierarchical frame selection and a bipartite token merging strategy to dynamically cluster key frames and selectively compress token sequences, striking a balance between computational efficiency with semantic richness. Extensive experiments across multiple benchmarks demonstrate the effectiveness of DYTO, achieving superior performance compared to both fine-tuned and training-free methods and setting a new state-of-the-art for zero-shot video understanding.

RankCLIP: Ranking-Consistent Language-Image Pretraining

Among the ever-evolving development of vision-language models, contrastive language-image pretraining (CLIP) has set new benchmarks in many downstream tasks such as zero-shot classifications by leveraging self-supervised contrastive learning on large amounts of text-image pairs. However, its dependency on rigid one-to-one mappings overlooks the complex and often multifaceted relationships between and within texts and images. To this end, we introduce RankCLIP, a novel pretraining method that extends beyond the rigid one-to-one matching framework of CLIP and its variants. By leveraging both in-modal and cross-modal ranking consistency, RankCLIP improves the alignment process, enabling it to capture the nuanced many-to-many relationships between and within each modality. Through comprehensive experiments, we demonstrate the enhanced capability of RankCLIP to effectively improve performance across various downstream tasks, notably achieving significant gains in zero-shot classifications over state-of-the-art methods, underscoring the potential of RankCLIP in further advancing vision-language pretraining.