Agent Hospital: A Simulacrum of Hospital with Evolvable Medical Agents

In this paper, we introduce a simulacrum of hospital called Agent Hospital that simulates the entire process of treating illness. All patients, nurses, and doctors are autonomous agents powered by large language models (LLMs). Our central goal is to enable a doctor agent to learn how to treat illness within the simulacrum. To do so, we propose a method called MedAgent-Zero. As the simulacrum can simulate disease onset and progression based on knowledge bases and LLMs, doctor agents can keep accumulating experience from both successful and unsuccessful cases. Simulation experiments show that the treatment performance of doctor agents consistently improves on various tasks. More interestingly, the knowledge the doctor agents have acquired in Agent Hospital is applicable to real-world medicare benchmarks. After treating around ten thousand patients (real-world doctors may take over two years), the evolved doctor agent achieves a state-of-the-art accuracy of 93.06% on a subset of the MedQA dataset that covers major respiratory diseases. This work paves the way for advancing the applications of LLM-powered agent techniques in medical scenarios.

ToMBench: Benchmarking Theory of Mind in Large Language Models

Theory of Mind (ToM) is the cognitive capability to perceive and ascribe mental states to oneself and others. Recent research has sparked a debate over whether large language models (LLMs) exhibit a form of ToM. However, existing ToM evaluations are hindered by challenges such as constrained scope, subjective judgment, and unintended contamination, yielding inadequate assessments. To address this gap, we introduce ToMBench with three key characteristics: a systematic evaluation framework encompassing 8 tasks and 31 abilities in social cognition, a multiple-choice question format to support automated and unbiased evaluation, and a build-from-scratch bilingual inventory to strictly avoid data leakage. Based on ToMBench, we conduct extensive experiments to evaluate the ToM performance of 10 popular LLMs across tasks and abilities. We find that even the most advanced LLMs like GPT-4 lag behind human performance by over 10% points, indicating that LLMs have not achieved a human-level theory of mind yet. Our aim with ToMBench is to enable an efficient and effective evaluation of LLMs' ToM capabilities, thereby facilitating the development of LLMs with inherent social intelligence.