6DGS: Enhanced Direction-Aware Gaussian Splatting for Volumetric Rendering

Novel view synthesis has advanced significantly with the development of neural radiance fields (NeRF) and 3D Gaussian splatting (3DGS). However, achieving high quality without compromising real-time rendering remains challenging, particularly for physically-based ray tracing with view-dependent effects. Recently, N-dimensional Gaussians (N-DG) introduced a 6D spatial-angular representation to better incorporate view-dependent effects, but the Gaussian representation and control scheme are sub-optimal. In this paper, we revisit 6D Gaussians and introduce 6D Gaussian Splatting (6DGS), which enhances color and opacity representations and leverages the additional directional information in the 6D space for optimized Gaussian control. Our approach is fully compatible with the 3DGS framework and significantly improves real-time radiance field rendering by better modeling view-dependent effects and fine details. Experiments demonstrate that 6DGS significantly outperforms 3DGS and N-DG, achieving up to a 15.73 dB improvement in PSNR with a reduction of 66.5% Gaussian points compared to 3DGS.

Auxiliary Input in Training: Incorporating Catheter Features into Deep Learning Models for ECG-Free Dynamic Coronary Roadmapping

Dynamic coronary roadmapping is a technology that overlays the vessel maps (the "roadmap") extracted from an offline image sequence of X-ray angiography onto a live stream of X-ray fluoroscopy in real-time. It aims to offer navigational guidance for interventional surgeries without the need for repeated contrast agent injections, thereby reducing the risks associated with radiation exposure and kidney failure. The precision of the roadmaps is contingent upon the accurate alignment of angiographic and fluoroscopic images based on their cardiac phases, as well as precise catheter tip tracking. The former ensures the selection of a roadmap that closely matches the vessel shape in the current frame, while the latter uses catheter tips as reference points to adjust for translational motion between the roadmap and the present vessel tree. Training deep learning models for both tasks is challenging and underexplored. However, incorporating catheter features into the models could offer substantial benefits, given humans heavily rely on catheters to complete the tasks. To this end, we introduce a simple but effective method, auxiliary input in training (AIT), and demonstrate that it enhances model performance across both tasks, outperforming baseline methods in knowledge incorporation and transfer learning.

Few-Shot 3D Volumetric Segmentation with Multi-Surrogate Fusion

Conventional 3D medical image segmentation methods typically require learning heavy 3D networks (e.g., 3D-UNet), as well as large amounts of in-domain data with accurate pixel/voxel-level labels to avoid overfitting. These solutions are thus extremely time- and labor-expensive, but also may easily fail to generalize to unseen objects during training. To alleviate this issue, we present MSFSeg, a novel few-shot 3D segmentation framework with a lightweight multi-surrogate fusion (MSF). MSFSeg is able to automatically segment unseen 3D objects/organs (during training) provided with one or a few annotated 2D slices or 3D sequence segments, via learning dense query-support organ/lesion anatomy correlations across patient populations. Our proposed MSF module mines comprehensive and diversified morphology correlations between unlabeled and the few labeled slices/sequences through multiple designated surrogates, making it able to generate accurate cross-domain 3D segmentation masks given annotated slices or sequences. We demonstrate the effectiveness of our proposed framework by showing superior performance on conventional few-shot segmentation benchmarks compared to prior art, and remarkable cross-domain cross-volume segmentation performance on proprietary 3D segmentation datasets for challenging entities, i.e., tubular structures, with only limited 2D or 3D labels.

Retrieval-augmented Few-shot Medical Image Segmentation with Foundation Models

Medical image segmentation is crucial for clinical decision-making, but the scarcity of annotated data presents significant challenges. Few-shot segmentation (FSS) methods show promise but often require retraining on the target domain and struggle to generalize across different modalities. Similarly, adapting foundation models like the Segment Anything Model (SAM) for medical imaging has limitations, including the need for finetuning and domain-specific adaptation. To address these issues, we propose a novel method that adapts DINOv2 and Segment Anything Model 2 (SAM 2) for retrieval-augmented few-shot medical image segmentation. Our approach uses DINOv2's feature as query to retrieve similar samples from limited annotated data, which are then encoded as memories and stored in memory bank. With the memory attention mechanism of SAM 2, the model leverages these memories as conditions to generate accurate segmentation of the target image. We evaluated our framework on three medical image segmentation tasks, demonstrating superior performance and generalizability across various modalities without the need for any retraining or finetuning. Overall, this method offers a practical and effective solution for few-shot medical image segmentation and holds significant potential as a valuable annotation tool in clinical applications.

Automated Patient Positioning with Learned 3D Hand Gestures

Positioning patients for scanning and interventional procedures is a critical task that requires high precision and accuracy. The conventional workflow involves manually adjusting the patient support to align the center of the target body part with the laser projector or other guiding devices. This process is not only time-consuming but also prone to inaccuracies. In this work, we propose an automated patient positioning system that utilizes a camera to detect specific hand gestures from technicians, allowing users to indicate the target patient region to the system and initiate automated positioning. Our approach relies on a novel multi-stage pipeline to recognize and interpret the technicians' gestures, translating them into precise motions of medical devices. We evaluate our proposed pipeline during actual MRI scanning procedures, using RGB-Depth cameras to capture the process. Results show that our system achieves accurate and precise patient positioning with minimal technician intervention. Furthermore, we validate our method on HaGRID, a large-scale hand gesture dataset, demonstrating its effectiveness in hand detection and gesture recognition.

Divide and Fuse: Body Part Mesh Recovery from Partially Visible Human Images

We introduce a novel bottom-up approach for human body mesh reconstruction, specifically designed to address the challenges posed by partial visibility and occlusion in input images. Traditional top-down methods, relying on whole-body parametric models like SMPL, falter when only a small part of the human is visible, as they require visibility of most of the human body for accurate mesh reconstruction. To overcome this limitation, our method employs a "Divide and Fuse (D&F)" strategy, reconstructing human body parts independently before fusing them, thereby ensuring robustness against occlusions. We design Human Part Parametric Models (HPPM) that independently reconstruct the mesh from a few shape and global-location parameters, without inter-part dependency. A specially designed fusion module then seamlessly integrates the reconstructed parts, even when only a few are visible. We harness a large volume of ground-truth SMPL data to train our parametric mesh models. To facilitate the training and evaluation of our method, we have established benchmark datasets featuring images of partially visible humans with HPPM annotations. Our experiments, conducted on these benchmark datasets, demonstrate the effectiveness of our D&F method, particularly in scenarios with substantial invisibility, where traditional approaches struggle to maintain reconstruction quality.

DDGS-CT: Direction-Disentangled Gaussian Splatting for Realistic Volume Rendering

Digitally reconstructed radiographs (DRRs) are simulated 2D X-ray images generated from 3D CT volumes, widely used in preoperative settings but limited in intraoperative applications due to computational bottlenecks, especially for accurate but heavy physics-based Monte Carlo methods. While analytical DRR renderers offer greater efficiency, they overlook anisotropic X-ray image formation phenomena, such as Compton scattering. We present a novel approach that marries realistic physics-inspired X-ray simulation with efficient, differentiable DRR generation using 3D Gaussian splatting (3DGS). Our direction-disentangled 3DGS (DDGS) method separates the radiosity contribution into isotropic and direction-dependent components, approximating complex anisotropic interactions without intricate runtime simulations. Additionally, we adapt the 3DGS initialization to account for tomography data properties, enhancing accuracy and efficiency. Our method outperforms state-of-the-art techniques in image accuracy. Furthermore, our DDGS shows promise for intraoperative applications and inverse problems such as pose registration, delivering superior registration accuracy and runtime performance compared to analytical DRR methods.

Self-learning Canonical Space for Multi-view 3D Human Pose Estimation

Multi-view 3D human pose estimation is naturally superior to single view one, benefiting from more comprehensive information provided by images of multiple views. The information includes camera poses, 2D/3D human poses, and 3D geometry. However, the accurate annotation of these information is hard to obtain, making it challenging to predict accurate 3D human pose from multi-view images. To deal with this issue, we propose a fully self-supervised framework, named cascaded multi-view aggregating network (CMANet), to construct a canonical parameter space to holistically integrate and exploit multi-view information. In our framework, the multi-view information is grouped into two categories: 1) intra-view information , 2) inter-view information. Accordingly, CMANet consists of two components: intra-view module (IRV) and inter-view module (IEV). IRV is used for extracting initial camera pose and 3D human pose of each view; IEV is to fuse complementary pose information and cross-view 3D geometry for a final 3D human pose. To facilitate the aggregation of the intra- and inter-view, we define a canonical parameter space, depicted by per-view camera pose and human pose and shape parameters ($\theta$ and $\beta$) of SMPL model, and propose a two-stage learning procedure. At first stage, IRV learns to estimate camera pose and view-dependent 3D human pose supervised by confident output of an off-the-shelf 2D keypoint detector. At second stage, IRV is frozen and IEV further refines the camera pose and optimizes the 3D human pose by implicitly encoding the cross-view complement and 3D geometry constraint, achieved by jointly fitting predicted multi-view 2D keypoints. The proposed framework, modules, and learning strategy are demonstrated to be effective by comprehensive experiments and CMANet is superior to state-of-the-art methods in extensive quantitative and qualitative analysis.

Human Mesh Recovery from Arbitrary Multi-view Images

Human mesh recovery from arbitrary multi-view images involves two characteristics: the arbitrary camera poses and arbitrary number of camera views. Because of the variability, designing a unified framework to tackle this task is challenging. The challenges can be summarized as the dilemma of being able to simultaneously estimate arbitrary camera poses and recover human mesh from arbitrary multi-view images while maintaining flexibility. To solve this dilemma, we propose a divide and conquer framework for Unified Human Mesh Recovery (U-HMR) from arbitrary multi-view images. In particular, U-HMR consists of a decoupled structure and two main components: camera and body decoupling (CBD), camera pose estimation (CPE), and arbitrary view fusion (AVF). As camera poses and human body mesh are independent of each other, CBD splits the estimation of them into two sub-tasks for two individual sub-networks (\ie, CPE and AVF) to handle respectively, thus the two sub-tasks are disentangled. In CPE, since each camera pose is unrelated to the others, we adopt a shared MLP to process all views in a parallel way. In AVF, in order to fuse multi-view information and make the fusion operation independent of the number of views, we introduce a transformer decoder with a SMPL parameters query token to extract cross-view features for mesh recovery. To demonstrate the efficacy and flexibility of the proposed framework and effect of each component, we conduct extensive experiments on three public datasets: Human3.6M, MPI-INF-3DHP, and TotalCapture.

Federated Data Model

In artificial intelligence (AI), especially deep learning, data diversity and volume play a pivotal role in model development. However, training a robust deep learning model often faces challenges due to data privacy, regulations, and the difficulty of sharing data between different locations, especially for medical applications. To address this, we developed a method called the Federated Data Model (FDM). This method uses diffusion models to learn the characteristics of data at one site and then creates synthetic data that can be used at another site without sharing the actual data. We tested this approach with a medical image segmentation task, focusing on cardiac magnetic resonance images from different hospitals. Our results show that models trained with this method perform well both on the data they were originally trained on and on data from other sites. This approach offers a promising way to train accurate and privacy-respecting AI models across different locations.