Enhancing super-resolution ultrasound localisation through multi-frame deconvolution exploiting spatiotemporal coherence

Super-resolution ultrasound imaging through microbubble (MB) localisation and tracking, also known as ultrasound localisation microscopy, allows non-invasive sub-diffraction resolution imaging of microvasculature in animals and humans. The number of MBs localised from the acquired contrast-enhanced ultrasound (CEUS) images and the localisation precision directly influence the quality of the resulting super-resolution microvasculature images. However, non-negligible noise present in the CEUS images can make localising MBs challenging. To enhance the MB localisation performance, we propose a Multi-Frame Deconvolution (MF-Decon) framework that can exploit the spatiotemporal coherence inherent in the CEUS data, with new spatial and temporal regularisers designed based on total variation (TV) and regularisation by denoising (RED). Based on the MF-Decon framework, we introduce two novel methods: MF-Decon with spatial and temporal TVs (MF-Decon+3DTV) and MF-Decon with spatial RED and temporal TV (MF-Decon+RED+TV). Results from in silico simulations indicate that our methods outperform two widely used methods using deconvolution or normalised cross-correlation across all evaluation metrics, including precision, recall, $F_1$ score, mean and standard localisation errors. In particular, our methods improve MB localisation precision by up to 39% and recall by up to 12%. Super-resolution microvasculature maps generated with our methods on a publicly available in vivo rat brain dataset show less noise, better contrast, higher resolution and more vessel structures.

Enhanced Generative Recommendation via Content and Collaboration Integration

Generative recommendation has emerged as a promising paradigm aimed at augmenting recommender systems with recent advancements in generative artificial intelligence. This task has been formulated as a sequence-to-sequence generation process, wherein the input sequence encompasses data pertaining to the user's previously interacted items, and the output sequence denotes the generative identifier for the suggested item. However, existing generative recommendation approaches still encounter challenges in (i) effectively integrating user-item collaborative signals and item content information within a unified generative framework, and (ii) executing an efficient alignment between content information and collaborative signals. In this paper, we introduce content-based collaborative generation for recommender systems, denoted as ColaRec. To capture collaborative signals, the generative item identifiers are derived from a pretrained collaborative filtering model, while the user is represented through the aggregation of interacted items' content. Subsequently, the aggregated textual description of items is fed into a language model to encapsulate content information. This integration enables ColaRec to amalgamate collaborative signals and content information within an end-to-end framework. Regarding the alignment, we propose an item indexing task to facilitate the mapping between the content-based semantic space and the interaction-based collaborative space. Additionally, a contrastive loss is introduced to ensure that items with similar collaborative GIDs possess comparable content representations, thereby enhancing alignment. To validate the efficacy of ColaRec, we conduct experiments on three benchmark datasets. Empirical results substantiate the superior performance of ColaRec.

A Fast Automatic Method for Deconvoluting Macro X-ray Fluorescence Data Collected from Easel Paintings

Macro X-ray Fluorescence (MA-XRF) scanning is increasingly widely used by researchers in heritage science to analyse easel paintings as one of a suite of non-invasive imaging techniques. The task of processing the resulting MA-XRF datacube generated in order to produce individual chemical element maps is called MA-XRF deconvolution. While there are several existing methods that have been proposed for MA-XRF deconvolution, they require a degree of manual intervention from the user that can affect the final results. The state-of-the-art AFRID approach can automatically deconvolute the datacube without user input, but it has a long processing time and does not exploit spatial dependency. In this paper, we propose two versions of a fast automatic deconvolution (FAD) method for MA-XRF datacubes collected from easel paintings with ADMM (alternating direction method of multipliers) and FISTA (fast iterative shrinkage-thresholding algorithm). The proposed FAD method not only automatically analyses the datacube and produces element distribution maps of high-quality with spatial dependency considered, but also significantly reduces the running time. The results generated on the MA-XRF datacubes collected from two easel paintings from the National Gallery, London, verify the performance of the proposed FAD method.

Beyond Keywords and Relevance: A Personalized Ad Retrieval Framework in E-Commerce Sponsored Search

On most sponsored search platforms, advertisers bid on some keywords for their advertisements (ads). Given a search request, ad retrieval module rewrites the query into bidding keywords, and uses these keywords as keys to select Top N ads through inverted indexes. In this way, an ad will not be retrieved even if queries are related when the advertiser does not bid on corresponding keywords. Moreover, most ad retrieval approaches regard rewriting and ad-selecting as two separated tasks, and focus on boosting relevance between search queries and ads. Recently, in e-commerce sponsored search more and more personalized information has been introduced, such as user profiles, long-time and real-time clicks. Personalized information makes ad retrieval able to employ more elements (e.g. real-time clicks) as search signals and retrieval keys, however it makes ad retrieval more difficult to measure ads retrieved through different signals. To address these problems, we propose a novel ad retrieval framework beyond keywords and relevance in e-commerce sponsored search. Firstly, we employ historical ad click data to initialize a hierarchical network representing signals, keys and ads, in which personalized information is introduced. Then we train a model on top of the hierarchical network by learning the weights of edges. Finally we select the best edges according to the model, boosting RPM/CTR. Experimental results on our e-commerce platform demonstrate that our ad retrieval framework achieves good performance.