Fracture interactive geodesic active contours for bone segmentation

For bone segmentation, the classical geodesic active contour model is usually limited by its indiscriminate feature extraction, and then struggles to handle the phenomena of edge obstruction, edge leakage and bone fracture. Thus, we propose a fracture interactive geodesic active contour algorithm tailored for bone segmentation, which can better capture bone features and perform robustly to the presence of bone fractures and soft tissues. Inspired by orthopedic knowledge, we construct a novel edge-detector function that combines the intensity and gradient norm, which guides the contour towards bone edges without being obstructed by other soft tissues and therefore reduces mis-segmentation. Furthermore, distance information, where fracture prompts can be embedded, is introduced into the contour evolution as an adaptive step size to stabilize the evolution and help the contour stop at bone edges and fractures. This embedding provides a way to interact with bone fractures and improves the accuracy in the fracture regions. Experiments in pelvic and ankle segmentation demonstrate the effectiveness on addressing the aforementioned problems and show an accurate, stable and consistent performance, indicating a broader application in other bone anatomies. Our algorithm also provides insights into combining the domain knowledge and deep neural networks.

LLM4MG: Adapting Large Language Model for Multipath Generation via Synesthesia of Machines

Based on Synesthesia of Machines (SoM), a large language model (LLM) is adapted for multipath generation (LLM4MG) for the first time. Considering a typical sixth-generation (6G) vehicle-to-infrastructure (V2I) scenario, a new multi-modal sensing-communication dataset is constructed, named SynthSoM-V2I, including channel multipath information, millimeter wave (mmWave) radar sensory data, RGB-D images, and light detection and ranging (LiDAR) point clouds. Based on the SynthSoM-V2I dataset, the proposed LLM4MG leverages Large Language Model Meta AI (LLaMA) 3.2 for multipath generation via multi-modal sensory data. The proposed LLM4MG aligns the multi-modal feature space with the LLaMA semantic space through feature extraction and fusion networks. To further achieve general knowledge transfer from the pre-trained LLaMA for multipath generation via multi-modal sensory data, the low-rank adaptation (LoRA) parameter-efficient fine-tuning and propagation-aware prompt engineering are exploited. Simulation results demonstrate that the proposed LLM4MG outperforms conventional deep learning-based methods in terms of line-of-sight (LoS)/non-LoS (NLoS) classification with accuracy of 92.76%, multipath power/delay generation precision with normalized mean square error (NMSE) of 0.099/0.032, and cross-vehicular traffic density (VTD), cross-band, and cross-scenario generalization. The utility of the proposed LLM4MG is validated by real-world generalization. The necessity of high-precision multipath generation for system design is also demonstrated by channel capacity comparison.

CURE: Controlled Unlearning for Robust Embeddings -- Mitigating Conceptual Shortcuts in Pre-Trained Language Models

Pre-trained language models have achieved remarkable success across diverse applications but remain susceptible to spurious, concept-driven correlations that impair robustness and fairness. In this work, we introduce CURE, a novel and lightweight framework that systematically disentangles and suppresses conceptual shortcuts while preserving essential content information. Our method first extracts concept-irrelevant representations via a dedicated content extractor reinforced by a reversal network, ensuring minimal loss of task-relevant information. A subsequent controllable debiasing module employs contrastive learning to finely adjust the influence of residual conceptual cues, enabling the model to either diminish harmful biases or harness beneficial correlations as appropriate for the target task. Evaluated on the IMDB and Yelp datasets using three pre-trained architectures, CURE achieves an absolute improvement of +10 points in F1 score on IMDB and +2 points on Yelp, while introducing minimal computational overhead. Our approach establishes a flexible, unsupervised blueprint for combating conceptual biases, paving the way for more reliable and fair language understanding systems.

Good Deep Features to Track: Self-Supervised Feature Extraction and Tracking in Visual Odometry

Visual-based localization has made significant progress, yet its performance often drops in large-scale, outdoor, and long-term settings due to factors like lighting changes, dynamic scenes, and low-texture areas. These challenges degrade feature extraction and tracking, which are critical for accurate motion estimation. While learning-based methods such as SuperPoint and SuperGlue show improved feature coverage and robustness, they still face generalization issues with out-of-distribution data. We address this by enhancing deep feature extraction and tracking through self-supervised learning with task specific feedback. Our method promotes stable and informative features, improving generalization and reliability in challenging environments.

Directed Evolution of Proteins via Bayesian Optimization in Embedding Space

Directed evolution is an iterative laboratory process of designing proteins with improved function by iteratively synthesizing new protein variants and evaluating their desired property with expensive and time-consuming biochemical screening. Machine learning methods can help select informative or promising variants for screening to increase their quality and reduce the amount of necessary screening. In this paper, we present a novel method for machine-learning-assisted directed evolution of proteins which combines Bayesian optimization with informative representation of protein variants extracted from a pre-trained protein language model. We demonstrate that the new representation based on the sequence embeddings significantly improves the performance of Bayesian optimization yielding better results with the same number of conducted screening in total. At the same time, our method outperforms the state-of-the-art machine-learning-assisted directed evolution methods with regression objective.

SitLLM: Large Language Models for Sitting Posture Health Understanding via Pressure Sensor Data

Poor sitting posture is a critical yet often overlooked factor contributing to long-term musculoskeletal disorders and physiological dysfunctions. Existing sitting posture monitoring systems, although leveraging visual, IMU, or pressure-based modalities, often suffer from coarse-grained recognition and lack the semantic expressiveness necessary for personalized feedback. In this paper, we propose \textbf{SitLLM}, a lightweight multimodal framework that integrates flexible pressure sensing with large language models (LLMs) to enable fine-grained posture understanding and personalized health-oriented response generation. SitLLM comprises three key components: (1) a \textit{Gaussian-Robust Sensor Embedding Module} that partitions pressure maps into spatial patches and injects local noise perturbations for robust feature extraction; (2) a \textit{Prompt-Driven Cross-Modal Alignment Module} that reprograms sensor embeddings into the LLM's semantic space via multi-head cross-attention using the pre-trained vocabulary embeddings; and (3) a \textit{Multi-Context Prompt Module} that fuses feature-level, structure-level, statistical-level, and semantic-level contextual information to guide instruction comprehension.

Scale-interaction transformer: a hybrid cnn-transformer model for facial beauty prediction

Automated Facial Beauty Prediction (FBP) is a challenging computer vision task due to the complex interplay of local and global facial features that influence human perception. While Convolutional Neural Networks (CNNs) excel at feature extraction, they often process information at a fixed scale, potentially overlooking the critical inter-dependencies between features at different levels of granularity. To address this limitation, we introduce the Scale-Interaction Transformer (SIT), a novel hybrid deep learning architecture that synergizes the feature extraction power of CNNs with the relational modeling capabilities of Transformers. The SIT first employs a multi-scale module with parallel convolutions to capture facial characteristics at varying receptive fields. These multi-scale representations are then framed as a sequence and processed by a Transformer encoder, which explicitly models their interactions and contextual relationships via a self-attention mechanism. We conduct extensive experiments on the widely-used SCUT-FBP5500 benchmark dataset, where the proposed SIT model establishes a new state-of-the-art. It achieves a Pearson Correlation of 0.9187, outperforming previous methods. Our findings demonstrate that explicitly modeling the interplay between multi-scale visual cues is crucial for high-performance FBP. The success of the SIT architecture highlights the potential of hybrid CNN-Transformer models for complex image regression tasks that demand a holistic, context-aware understanding.

Dual-Scale Volume Priors with Wasserstein-Based Consistency for Semi-Supervised Medical Image Segmentation

Despite signi cant progress in semi-supervised medical image segmentation, most existing segmentation networks overlook e ective methodological guidance for feature extraction and important prior information from datasets. In this paper, we develop a semi-supervised medical image segmentation framework that e ectively integrates spatial regularization methods and volume priors. Speci cally, our approach integrates a strong explicit volume prior at the image scale and Threshold Dynamics spatial regularization, both derived from variational models, into the backbone segmentation network. The target region volumes for each unlabeled image are estimated by a regression network, which e ectively regularizes the backbone segmentation network through an image-scale Wasserstein distance constraint, ensuring that the class ratios in the segmentation results for each unlabeled image match those predicted by the regression network. Additionally, we design a dataset-scale Wasserstein distance loss function based on a weak implicit volume prior, which enforces that the volume distribution predicted for the unlabeled dataset is similar to that of labeled dataset. Experimental results on the 2017 ACDC dataset, PROMISE12 dataset, and thigh muscle MR image dataset show the superiority of the proposed method.

Dual-Mode Visual System for Brain-Computer Interfaces: Integrating SSVEP and P300 Responses

In brain-computer interface (BCI) systems, steady-state visual evoked potentials (SSVEP) and P300 responses have achieved widespread implementation owing to their superior information transfer rates (ITR) and minimal training requirements. These neurophysiological signals have exhibited robust efficacy and versatility in external device control, demonstrating enhanced precision and scalability. However, conventional implementations predominantly utilise liquid crystal display (LCD)-based visual stimulation paradigms, which present limitations in practical deployment scenarios. This investigation presents the development and evaluation of a novel light-emitting diode (LED)-based dual stimulation apparatus designed to enhance SSVEP classification accuracy through the integration of both SSVEP and P300 paradigms. The system employs four distinct frequencies, 7 Hz, 8 Hz, 9 Hz, and 10 Hz, corresponding to forward, backward, right, and left directional controls, respectively. Oscilloscopic verification confirmed the precision of these stimulation frequencies. Real-time feature extraction was accomplished through the concurrent analysis of maximum Fast Fourier Transform (FFT) amplitude and P300 peak detection to ascertain user intent. Directional control was determined by the frequency exhibiting maximal amplitude characteristics. The visual stimulation hardware demonstrated minimal frequency deviation, with error differentials ranging from 0.15%to 0.20%across all frequencies. The implemented signal processing algorithm successfully discriminated all four stimulus frequencies whilst correlating them with their respective P300 event markers. Classification accuracy was evaluated based on correct task intention recognition. The proposed hybrid system achieved a mean classification accuracy of 86.25%, coupled with an average ITR of 42.08 bits per minute (bpm).

A Knowledge Noise Mitigation Framework for Knowledge-based Visual Question Answering

Knowledge-based visual question answering (KB-VQA) requires a model to understand images and utilize external knowledge to provide accurate answers. Existing approaches often directly augment models with retrieved information from knowledge sources while ignoring substantial knowledge redundancy, which introduces noise into the answering process. To address this, we propose a training-free framework with knowledge focusing for KB-VQA, that mitigates the impact of noise by enhancing knowledge relevance and reducing redundancy. First, for knowledge retrieval, our framework concludes essential parts from the image-question pairs, creating low-noise queries that enhance the retrieval of highly relevant knowledge. Considering that redundancy still persists in the retrieved knowledge, we then prompt large models to identify and extract answer-beneficial segments from knowledge. In addition, we introduce a selective knowledge integration strategy, allowing the model to incorporate knowledge only when it lacks confidence in answering the question, thereby mitigating the influence of redundant information. Our framework enables the acquisition of accurate and critical knowledge, and extensive experiments demonstrate that it outperforms state-of-the-art methods.