Brief2Design: A Multi-phased, Compositional Approach to Prompt-based Graphic Design

Professional designers work from client briefs that specify goals and constraints but often lack concrete design details. Translating these abstract requirements into visual designs poses a central challenge, yet existing tools address specific aspects or induce fixation through complete outputs. Through interviews with six professional designers, we identified how designers address this challenge: first structuring ambiguous requirements, then exploring individual elements, and finally recombining alternatives. We developed Brief2Design, supporting this workflow through requirement extraction and recommendation, element-level exploration for objects, backgrounds, text, typography, and composition, and flexible recombination of selected elements. A within-subjects study with twelve designers compared Brief2Design against a conversational baseline. The structured approach increased prompt diversity and received high ratings for requirement extraction and recommendation, but required longer generation time and achieved comparable image diversity. These findings reveal that structured workflows benefit requirement clarification at the cost of efficiency, informing design trade-offs for AI-assisted graphic design tools.

Rethinking Uncertainty in Segmentation: From Estimation to Decision

In medical image segmentation, uncertainty estimates are often reported but rarely used to guide decisions. We study the missing step: how uncertainty maps are converted into actionable policies such as accepting, flagging, or deferring predictions. We formulate segmentation as a two-stage pipeline, estimation followed by decision, and show that optimizing uncertainty alone fails to capture most of the achievable safety gains. Using retinal vessel segmentation benchmarks (DRIVE, STARE, CHASE_DB1), we evaluate two uncertainty sources (Monte Carlo Dropout and Test-Time Augmentation) combined with three deferral strategies, and introduce a simple confidence-aware deferral rule that prioritizes uncertain and low-confidence predictions. Our results show that the best method and policy combination removes up to 80 percent of segmentation errors at only 25 percent pixel deferral, while achieving strong cross-dataset robustness. We further show that calibration improvements do not translate to better decision quality, highlighting a disconnect between standard uncertainty metrics and real-world utility. These findings suggest that uncertainty should be evaluated based on the decisions it enables, rather than in isolation.

Conflated Inverse Modeling to Generate Diverse and Temperature-Change Inducing Urban Vegetation Patterns

Urban areas are increasingly vulnerable to thermal extremes driven by rapid urbanization and climate change. Traditionally, thermal extremes have been monitored using Earth-observing satellites and numerical modeling frameworks. For example, land surface temperature derived from Landsat or Sentinel imagery is commonly used to characterize surface heating patterns. These approaches operate as forward models, translating radiative observations or modeled boundary conditions into estimates of surface thermal states. While forward models can predict land surface temperature from vegetation and urban form, the inverse problem of determining spatial vegetation configurations that achieve a desired regional temperature shift remains largely unexplored. This task is inherently underdetermined, as multiple spatial vegetation patterns can yield similar aggregated temperature responses. Conventional regression and deterministic neural networks fail to capture this ambiguity and often produce averaged solutions, particularly under data-scarce conditions. We propose a conflated inverse modeling framework that combines a predictive forward model with a diffusion-based generative inverse model to produce diverse, physically plausible image-based vegetation patterns conditioned on specific temperature goals. Our framework maintains control over thermal outcomes while enabling diverse spatial vegetation configurations, even when such combinations are absent from training data. Altogether, this work introduces a controllable inverse modeling approach for urban climate adaptation that accounts for the inherent diversity of the problem. Code is available at the GitHub repository.

Human Pose Estimation in Trampoline Gymnastics: Improving Performance Using a New Synthetic Dataset

Trampoline gymnastics involves extreme human poses and uncommon viewpoints, on which state-of-the art pose estimation models tend to under-perform. We demonstrate that this problem can be addressed by fine-tuning a pose estimation model on a dataset of synthetic trampoline poses (STP). STP is generated from motion capture recordings of trampoline routines. We develop a pipeline to fit noisy motion capture data to a parametric human model, then generate multiview realistic images. We use this data to fine-tune a ViTPose model, and test it on real multi-view trampoline images. The resulting model exhibits accuracy improvements in 2D which translates to improved 3D triangulation. In 2D, we obtain state-of-the-art results on such challenging data, bridging the performance gap between common and extreme poses. In 3D, we reduce the MPJPE by 12.5 mm with our best model, which represents an improvement of 19.6% compared to the pretrained ViTPose model.

AnyUser: Translating Sketched User Intent into Domestic Robots

We introduce AnyUser, a unified robotic instruction system for intuitive domestic task instruction via free-form sketches on camera images, optionally with language. AnyUser interprets multimodal inputs (sketch, vision, language) as spatial-semantic primitives to generate executable robot actions requiring no prior maps or models. Novel components include multimodal fusion for understanding and a hierarchical policy for robust action generation. Efficacy is shown via extensive evaluations: (1) Quantitative benchmarks on the large-scale dataset showing high accuracy in interpreting diverse sketch-based commands across various simulated domestic scenes. (2) Real-world validation on two distinct robotic platforms, a statically mounted 7-DoF assistive arm (KUKA LBR iiwa) and a dual-arm mobile manipulator (Realman RMC-AIDAL), performing representative tasks like targeted wiping and area cleaning, confirming the system's ability to ground instructions and execute them reliably in physical environments. (3) A comprehensive user study involving diverse demographics (elderly, simulated non-verbal, low technical literacy) demonstrating significant improvements in usability and task specification efficiency, achieving high task completion rates (85.7%-96.4%) and user satisfaction. AnyUser bridges the gap between advanced robotic capabilities and the need for accessible non-expert interaction, laying the foundation for practical assistive robots adaptable to real-world human environments.

Uncertainty Quantification for Distribution-to-Distribution Flow Matching in Scientific Imaging

Distribution-to-distribution generative models support scientific imaging tasks ranging from modeling cellular perturbation responses to translating medical images across conditions. Trustworthy generation requires both reliability (generalization across labs, devices, and experimental conditions) and accountability (detecting out-of-distribution cases where predictions may be unreliable). Uncertainty quantification (UQ) based approaches serve as promising candidates for these tasks, yet UQ for distribution-to-distribution generative models remains underexplored. We present a unified UQ framework, Bayesian Stochastic Flow Matching (BSFM), that disentangles aleatoric and epistemic uncertainty. The Stochastic Flow Matching (SFM) component augments deterministic flows with a diffusion term to improve model generalization to unseen scenarios. For UQ, we develop a scalable Bayesian approach -- MCD-Antithetic -- that combines Monte Carlo Dropout with sample-efficient antithetic sampling to produce effective anomaly scores for out-of-distribution detection. Experiments on cellular imaging (BBBC021, JUMP) and brain fMRI (Theory of Mind) across diverse scenarios show that SFM improves reliability while MCD-Antithetic enhances accountability.

Image-based Quantification of Postural Deviations on Patients with Cervical Dystonia: A Machine Learning Approach Using Synthetic Training Data

Cervical dystonia (CD) is the most common form of dystonia, yet current assessment relies on subjective clinical rating scales, such as the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS), which requires expertise, is subjective and faces low inter-rater reliability some items of the score. To address the lack of established objective tools for monitoring disease severity and treatment response, this study validates an automated image-based head pose and shift estimation system for patients with CD. We developed an assessment tool that combines a pretrained head-pose estimation algorithm for rotational symptoms with a deep learning model trained exclusively on ~16,000 synthetic avatar images to evaluate rare translational symptoms, specifically lateral shift. This synthetic data approach overcomes the scarcity of clinical training examples. The system's performance was validated in a multicenter study by comparing its predicted scores against the consensus ratings of 20 clinical experts using a dataset of 100 real patient images and 100 labeled synthetic avatars. The automated system demonstrated strong agreement with expert clinical ratings for rotational symptoms, achieving high correlations for torticollis (r=0.91), laterocollis (r=0.81), and anteroretrocollis (r=0.78). For lateral shift, the tool achieved a moderate correlation (r=0.55) with clinical ratings and demonstrated higher accuracy than human raters in controlled benchmark tests on avatars. By leveraging synthetic training data to bridge the clinical data gap, this model successfully generalizes to real-world patients, providing a validated, objective tool for CD postural assessment that can enable standardized clinical decision-making and trial evaluation.

Automated Detection of Multiple Sclerosis Lesions on 7-tesla MRI Using U-net and Transformer-based Segmentation

Ultra-high field 7-tesla (7T) MRI improves visualization of multiple sclerosis (MS) white matter lesions (WML) but differs sufficiently in contrast and artifacts from 1.5-3T imaging - suggesting that widely used automated segmentation tools may not translate directly. We analyzed 7T FLAIR scans and generated reference WML masks from Lesion Segmentation Tool (LST) outputs followed by expert manual revision. As external comparators, we applied LST-LPA and the more recent LST-AI ensemble, both originally developed on lower-field data. We then trained 3D UNETR and SegFormer transformer-based models on 7T FLAIR at multiple resolutions (0.5x0.5x0.5^3, 1.0x1.0x1.0^3, and 1.5x1.5x2.0^3) and evaluated all methods using voxel-wise and lesion-wise metrics from the BraTS 2023 framework. On the held-out test set at native 0.5x0.5x0.5^3 resolution, 7T-trained transformers achieved competitive overlap with LST-AI while recovering additional small lesions that were missed by classical methods, at the cost of some boundary variability and occasional artifact-related false positives. On a held-out 7 T test set, our best transformer model (SegFormer) achieved a voxel-wise Dice of 0.61 and lesion-wise Dice of 0.20, improving on the classical LST-LPA tool (Dice 0.39, lesion-wise Dice 0.02). Performance decreased for models trained on downsampled images, underscoring the value of native 7T resolution for small-lesion detection. By releasing our 7T-trained models, we aim to provide a reproducible, ready-to-use resource for automated lesion quantification in ultra-high field MS research (https://github.com/maynord/7T-MS-lesion-segmentation).

TuLaBM: Tumor-Biased Latent Bridge Matching for Contrast-Enhanced MRI Synthesis

Contrast-enhanced magnetic resonance imaging (CE-MRI) plays a crucial role in brain tumor assessment; however, its acquisition requires gadolinium-based contrast agents (GBCAs), which increase costs and raise safety concerns. Consequently, synthesizing CE-MRI from non-contrast MRI (NC-MRI) has emerged as a promising alternative. Early Generative Adversarial Network (GAN)-based approaches suffered from instability and mode collapse, while diffusion models, despite impressive synthesis quality, remain computationally expensive and often fail to faithfully reproduce critical tumor contrast patterns. To address these limitations, we propose Tumor-Biased Latent Bridge Matching (TuLaBM), which formulates NC-to-CE MRI translation as Brownian bridge transport between source and target distributions in a learned latent space, enabling efficient training and inference. To enhance tumor-region fidelity, we introduce a Tumor-Biased Attention Mechanism (TuBAM) that amplifies tumor-relevant latent features during bridge evolution, along with a boundary-aware loss that constrains tumor interfaces to improve margin sharpness. While bridge matching has been explored for medical image translation in pixel space, our latent formulation substantially reduces computational cost and inference time. Experiments on BraTS2023-GLI (BraSyn) and Cleveland Clinic (in-house) liver MRI dataset show that TuLaBM consistently outperforms state-of-the-art baselines on both whole-image and tumor-region metrics, generalizes effectively to unseen liver MRI data in zero-shot and fine-tuned settings, and achieves inference times under 0.097 seconds per image.

Relational Epipolar Graphs for Robust Relative Camera Pose Estimation

A key component of Visual Simultaneous Localization and Mapping (VSLAM) is estimating relative camera poses using matched keypoints. Accurate estimation is challenged by noisy correspondences. Classical methods rely on stochastic hypothesis sampling and iterative estimation, while learning-based methods often lack explicit geometric structure. In this work, we reformulate relative pose estimation as a relational inference problem over epipolar correspondence graphs, where matched keypoints are nodes and nearby ones are connected by edges. Graph operations such as pruning, message passing, and pooling estimate a quaternion rotation, translation vector, and the Essential Matrix (EM). Minimizing a loss comprising (i) $\mathcal{L}_2$ differences with ground truth (GT), (ii) Frobenius norm between estimated and GT EMs, (iii) singular value differences, (iv) heading angle differences, and (v) scale differences, yields the relative pose between image pairs. The dense detector-free method LoFTR is used for matching. Experiments on indoor and outdoor benchmarks show improved robustness to dense noise and large baseline variation compared to classical and learning-guided approaches, highlighting the effectiveness of global relational consensus.