System-Level Error Propagation and Tail-Risk Amplification in Reference-Based Robotic Navigation

Image guided robotic navigation systems often rely on reference based geometric perception pipelines, where accurate spatial mapping is established through multi stage estimation processes. In biplanar X ray guided navigation, such pipelines are widely used due to their real time capability and geometric interpretability. However, navigation reliability can be constrained by an overlooked system level failure mechanism in which installation induced structural perturbations introduced at the perception stage are progressively amplified along the perception reconstruction execution chain and dominate execution level error and tail risk behavior. This paper investigates this mechanism from a system level perspective and presents a unified error propagation modeling framework that characterizes how installation induced structural perturbations propagate and couple with pixel level observation noise through biplanar imaging, projection matrix estimation, triangulation, and coordinate mapping. Using first order analytic uncertainty propagation and Monte Carlo simulations, we analyze dominant sensitivity channels and quantify worst case error behavior beyond mean accuracy metrics. The results show that rotational installation error is a primary driver of system level error amplification, while translational misalignment of comparable magnitude plays a secondary role under typical biplanar geometries. Real biplanar X ray bench top experiments further confirm that the predicted amplification trends persist under realistic imaging conditions. These findings reveal a broader structural limitation of reference based multi stage geometric perception pipelines and provide a framework for system level reliability analysis and risk aware design in safety critical robotic navigation systems.

SOMA-1M: A Large-Scale SAR-Optical Multi-resolution Alignment Dataset for Multi-Task Remote Sensing

Synthetic Aperture Radar (SAR) and optical imagery provide complementary strengths that constitute the critical foundation for transcending single-modality constraints and facilitating cross-modal collaborative processing and intelligent interpretation. However, existing benchmark datasets often suffer from limitations such as single spatial resolution, insufficient data scale, and low alignment accuracy, making them inadequate for supporting the training and generalization of multi-scale foundation models. To address these challenges, we introduce SOMA-1M (SAR-Optical Multi-resolution Alignment), a pixel-level precisely aligned dataset containing over 1.3 million pairs of georeferenced images with a specification of 512 x 512 pixels. This dataset integrates imagery from Sentinel-1, PIESAT-1, Capella Space, and Google Earth, achieving global multi-scale coverage from 0.5 m to 10 m. It encompasses 12 typical land cover categories, effectively ensuring scene diversity and complexity. To address multimodal projection deformation and massive data registration, we designed a rigorous coarse-to-fine image matching framework ensuring pixel-level alignment. Based on this dataset, we established comprehensive evaluation benchmarks for four hierarchical vision tasks, including image matching, image fusion, SAR-assisted cloud removal, and cross-modal translation, involving over 30 mainstream algorithms. Experimental results demonstrate that supervised training on SOMA-1M significantly enhances performance across all tasks. Notably, multimodal remote sensing image (MRSI) matching performance achieves current state-of-the-art (SOTA) levels. SOMA-1M serves as a foundational resource for robust multimodal algorithms and remote sensing foundation models. The dataset will be released publicly at: https://github.com/PeihaoWu/SOMA-1M.

A generalizable large-scale foundation model for musculoskeletal radiographs

Artificial intelligence (AI) has shown promise in detecting and characterizing musculoskeletal diseases from radiographs. However, most existing models remain task-specific, annotation-dependent, and limited in generalizability across diseases and anatomical regions. Although a generalizable foundation model trained on large-scale musculoskeletal radiographs is clinically needed, publicly available datasets remain limited in size and lack sufficient diversity to enable training across a wide range of musculoskeletal conditions and anatomical sites. Here, we present SKELEX, a large-scale foundation model for musculoskeletal radiographs, trained using self-supervised learning on 1.2 million diverse, condition-rich images. The model was evaluated on 12 downstream diagnostic tasks and generally outperformed baselines in fracture detection, osteoarthritis grading, and bone tumor classification. Furthermore, SKELEX demonstrated zero-shot abnormality localization, producing error maps that identified pathologic regions without task-specific training. Building on this capability, we developed an interpretable, region-guided model for predicting bone tumors, which maintained robust performance on independent external datasets and was deployed as a publicly accessible web application. Overall, SKELEX provides a scalable, label-efficient, and generalizable AI framework for musculoskeletal imaging, establishing a foundation for both clinical translation and data-efficient research in musculoskeletal radiology.

Recovering 3D Shapes from Ultra-Fast Motion-Blurred Images

We consider the problem of 3D shape recovery from ultra-fast motion-blurred images. While 3D reconstruction from static images has been extensively studied, recovering geometry from extreme motion-blurred images remains challenging. Such scenarios frequently occur in both natural and industrial settings, such as fast-moving objects in sports (e.g., balls) or rotating machinery, where rapid motion distorts object appearance and makes traditional 3D reconstruction techniques like Multi-View Stereo (MVS) ineffective. In this paper, we propose a novel inverse rendering approach for shape recovery from ultra-fast motion-blurred images. While conventional rendering techniques typically synthesize blur by averaging across multiple frames, we identify a major computational bottleneck in the repeated computation of barycentric weights. To address this, we propose a fast barycentric coordinate solver, which significantly reduces computational overhead and achieves a speedup of up to 4.57x, enabling efficient and photorealistic simulation of high-speed motion. Crucially, our method is fully differentiable, allowing gradients to propagate from rendered images to the underlying 3D shape, thereby facilitating shape recovery through inverse rendering. We validate our approach on two representative motion types: rapid translation and rotation. Experimental results demonstrate that our method enables efficient and realistic modeling of ultra-fast moving objects in the forward simulation. Moreover, it successfully recovers 3D shapes from 2D imagery of objects undergoing extreme translational and rotational motion, advancing the boundaries of vision-based 3D reconstruction. Project page: https://maxmilite.github.io/rec-from-ultrafast-blur/

ShapeUP: Scalable Image-Conditioned 3D Editing

Recent advancements in 3D foundation models have enabled the generation of high-fidelity assets, yet precise 3D manipulation remains a significant challenge. Existing 3D editing frameworks often face a difficult trade-off between visual controllability, geometric consistency, and scalability. Specifically, optimization-based methods are prohibitively slow, multi-view 2D propagation techniques suffer from visual drift, and training-free latent manipulation methods are inherently bound by frozen priors and cannot directly benefit from scaling. In this work, we present ShapeUP, a scalable, image-conditioned 3D editing framework that formulates editing as a supervised latent-to-latent translation within a native 3D representation. This formulation allows ShapeUP to build on a pretrained 3D foundation model, leveraging its strong generative prior while adapting it to editing through supervised training. In practice, ShapeUP is trained on triplets consisting of a source 3D shape, an edited 2D image, and the corresponding edited 3D shape, and learns a direct mapping using a 3D Diffusion Transformer (DiT). This image-as-prompt approach enables fine-grained visual control over both local and global edits and achieves implicit, mask-free localization, while maintaining strict structural consistency with the original asset. Our extensive evaluations demonstrate that ShapeUP consistently outperforms current trained and training-free baselines in both identity preservation and edit fidelity, offering a robust and scalable paradigm for native 3D content creation.

PMPBench: A Paired Multi-Modal Pan-Cancer Benchmark for Medical Image Synthesis

Contrast medium plays a pivotal role in radiological imaging, as it amplifies lesion conspicuity and improves detection for the diagnosis of tumor-related diseases. However, depending on the patient's health condition or the medical resources available, the use of contrast medium is not always feasible. Recent work has explored AI-based image translation to synthesize contrast-enhanced images directly from non-contrast scans, aims to reduce side effects and streamlines clinical workflows. Progress in this direction has been constrained by data limitations: (1) existing public datasets focus almost exclusively on brain-related paired MR modalities; (2) other collections include partially paired data but suffer from missing modalities/timestamps and imperfect spatial alignment; (3) explicit labeling of CT vs. CTC or DCE phases is often absent; (4) substantial resources remain private. To bridge this gap, we introduce the first public, fully paired, pan-cancer medical imaging dataset spanning 11 human organs. The MR data include complete dynamic contrast-enhanced (DCE) sequences covering all three phases (DCE1-DCE3), while the CT data provide paired non-contrast and contrast-enhanced acquisitions (CTC). The dataset is curated for anatomical correspondence, enabling rigorous evaluation of 1-to-1, N-to-1, and N-to-N translation settings (e.g., predicting DCE phases from non-contrast inputs). Built upon this resource, we establish a comprehensive benchmark. We report results from representative baselines of contemporary image-to-image translation. We release the dataset and benchmark to catalyze research on safe, effective contrast synthesis, with direct relevance to multi-organ oncology imaging workflows. Our code and dataset are publicly available at https://github.com/YifanChen02/PMPBench.

Finite-time Stable Pose Estimation on TSE(3) using Point Cloud and Velocity Sensors

This work presents a finite-time stable pose estimator (FTS-PE) for rigid bodies undergoing rotational and translational motion in three dimensions, using measurements from onboard sensors that provide position vectors to inertially-fixed points and body velocities. The FTS-PE is a full-state observer for the pose (position and orientation) and velocities and is obtained through a Lyapunov analysis that shows its stability in finite time and its robustness to bounded measurement noise. Further, this observer is designed directly on the state space, the tangent bundle of the Lie group of rigid body motions, SE(3), without using local coordinates or (dual) quaternion representations. Therefore, it can estimate arbitrary rigid body motions without encountering singularities or the unwinding phenomenon and be readily applied to autonomous vehicles. A version of this observer that does not need translational velocity measurements and uses only point clouds and angular velocity measurements from rate gyros, is also obtained. It is discretized using the framework of geometric mechanics for numerical and experimental implementations. The numerical simulations compare the FTS-PE with a dual-quaternion extended Kalman filter and our previously developed variational pose estimator (VPE). The experimental results are obtained using point cloud images and rate gyro measurements obtained from a Zed 2i stereo depth camera sensor. These results validate the stability and robustness of the FTS-PE.

Cross-Domain Object Detection Using Unsupervised Image Translation

Unsupervised domain adaptation for object detection addresses the adaption of detectors trained in a source domain to work accurately in an unseen target domain. Recently, methods approaching the alignment of the intermediate features proven to be promising, achieving state-of-the-art results. However, these methods are laborious to implement and hard to interpret. Although promising, there is still room for improvements to close the performance gap toward the upper-bound (when training with the target data). In this work, we propose a method to generate an artificial dataset in the target domain to train an object detector. We employed two unsupervised image translators (CycleGAN and an AdaIN-based model) using only annotated data from the source domain and non-annotated data from the target domain. Our key contributions are the proposal of a less complex yet more effective method that also has an improved interpretability. Results on real-world scenarios for autonomous driving show significant improvements, outperforming state-of-the-art methods in most cases, further closing the gap toward the upper-bound.

Sim2real Image Translation Enables Viewpoint-Robust Policies from Fixed-Camera Datasets

Vision-based policies for robot manipulation have achieved significant recent success, but are still brittle to distribution shifts such as camera viewpoint variations. Robot demonstration data is scarce and often lacks appropriate variation in camera viewpoints. Simulation offers a way to collect robot demonstrations at scale with comprehensive coverage of different viewpoints, but presents a visual sim2real challenge. To bridge this gap, we propose MANGO -- an unpaired image translation method with a novel segmentation-conditioned InfoNCE loss, a highly-regularized discriminator design, and a modified PatchNCE loss. We find that these elements are crucial for maintaining viewpoint consistency during sim2real translation. When training MANGO, we only require a small amount of fixed-camera data from the real world, but show that our method can generate diverse unseen viewpoints by translating simulated observations. In this domain, MANGO outperforms all other image translation methods we tested. Imitation-learning policies trained on data augmented by MANGO are able to achieve success rates as high as 60\% on views that the non-augmented policy fails completely on.

Semi-Supervised Domain Adaptation with Latent Diffusion for Pathology Image Classification

Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches either fail to leverage unlabeled data from the target domain or rely on image-to-image translation, which can distort tissue structures and compromise model accuracy. In this work, we propose a semi-supervised domain adaptation (SSDA) framework that utilizes a latent diffusion model trained on unlabeled data from both the source and target domains to generate morphology-preserving and target-aware synthetic images. By conditioning the diffusion model on foundation model features, cohort identity, and tissue preparation method, we preserve tissue structure in the source domain while introducing target-domain appearance characteristics. The target-aware synthetic images, combined with real, labeled images from the source cohort, are subsequently used to train a downstream classifier, which is then tested on the target cohort. The effectiveness of the proposed SSDA framework is demonstrated on the task of lung adenocarcinoma prognostication. The proposed augmentation yielded substantially better performance on the held-out test set from the target cohort, without degrading source-cohort performance. The approach improved the weighted F1 score on the target-cohort held-out test set from 0.611 to 0.706 and the macro F1 score from 0.641 to 0.716. Our results demonstrate that target-aware diffusion-based synthetic data augmentation provides a promising and effective approach for improving domain generalization in computational pathology.