Learning to Detect Multi-class Anomalies with Just One Normal Image Prompt

Unsupervised reconstruction networks using self-attention transformers have achieved state-of-the-art performance for multi-class (unified) anomaly detection with a single model. However, these self-attention reconstruction models primarily operate on target features, which may result in perfect reconstruction for both normal and anomaly features due to high consistency with context, leading to failure in detecting anomalies. Additionally, these models often produce inaccurate anomaly segmentation due to performing reconstruction in a low spatial resolution latent space. To enable reconstruction models enjoying high efficiency while enhancing their generalization for unified anomaly detection, we propose a simple yet effective method that reconstructs normal features and restores anomaly features with just One Normal Image Prompt (OneNIP). In contrast to previous work, OneNIP allows for the first time to reconstruct or restore anomalies with just one normal image prompt, effectively boosting unified anomaly detection performance. Furthermore, we propose a supervised refiner that regresses reconstruction errors by using both real normal and synthesized anomalous images, which significantly improves pixel-level anomaly segmentation. OneNIP outperforms previous methods on three industry anomaly detection benchmarks: MVTec, BTAD, and VisA. The code and pre-trained models are available at https://github.com/gaobb/OneNIP.

Behind the Noise: Conformal Quantile Regression Reveals Emergent Representations

Scientific imaging often involves long acquisition times to obtain high-quality data, especially when probing complex, heterogeneous systems. However, reducing acquisition time to increase throughput inevitably introduces significant noise into the measurements. We present a machine learning approach that not only denoises low-quality measurements with calibrated uncertainty bounds, but also reveals emergent structure in the latent space. By using ensembles of lightweight, randomly structured neural networks trained via conformal quantile regression, our method performs reliable denoising while uncovering interpretable spatial and chemical features -- without requiring labels or segmentation. Unlike conventional approaches focused solely on image restoration, our framework leverages the denoising process itself to drive the emergence of meaningful representations. We validate the approach on real-world geobiochemical imaging data, showing how it supports confident interpretation and guides experimental design under resource constraints.

Total Variation-Based Image Decomposition and Denoising for Microscopy Images

Experimentally acquired microscopy images are unavoidably affected by the presence of noise and other unwanted signals, which degrade their quality and might hide relevant features. With the recent increase in image acquisition rate, modern denoising and restoration solutions become necessary. This study focuses on image decomposition and denoising of microscopy images through a workflow based on total variation (TV), addressing images obtained from various microscopy techniques, including atomic force microscopy (AFM), scanning tunneling microscopy (STM), and scanning electron microscopy (SEM). Our approach consists in restoring an image by extracting its unwanted signal components and subtracting them from the raw one, or by denoising it. We evaluate the performance of TV-$L^1$, Huber-ROF, and TGV-$L^1$ in achieving this goal in distinct study cases. Huber-ROF proved to be the most flexible one, while TGV-$L^1$ is the most suitable for denoising. Our results suggest a wider applicability of this method in microscopy, restricted not only to STM, AFM, and SEM images. The Python code used for this study is publicly available as part of AiSurf. It is designed to be integrated into experimental workflows for image acquisition or can be used to denoise previously acquired images.

Highly Undersampled MRI Reconstruction via a Single Posterior Sampling of Diffusion Models

Incoherent k-space under-sampling and deep learning-based reconstruction methods have shown great success in accelerating MRI. However, the performance of most previous methods will degrade dramatically under high acceleration factors, e.g., 8$\times$ or higher. Recently, denoising diffusion models (DM) have demonstrated promising results in solving this issue; however, one major drawback of the DM methods is the long inference time due to a dramatic number of iterative reverse posterior sampling steps. In this work, a Single Step Diffusion Model-based reconstruction framework, namely SSDM-MRI, is proposed for restoring MRI images from highly undersampled k-space. The proposed method achieves one-step reconstruction by first training a conditional DM and then iteratively distilling this model. Comprehensive experiments were conducted on both publicly available fastMRI images and an in-house multi-echo GRE (QSM) subject. Overall, the results showed that SSDM-MRI outperformed other methods in terms of numerical metrics (PSNR and SSIM), qualitative error maps, image fine details, and latent susceptibility information hidden in MRI phase images. In addition, the reconstruction time for a 320*320 brain slice of SSDM-MRI is only 0.45 second, which is only comparable to that of a simple U-net, making it a highly effective solution for MRI reconstruction tasks.

Unsupervised Raindrop Removal from a Single Image using Conditional Diffusion Models

Raindrop removal is a challenging task in image processing. Removing raindrops while relying solely on a single image further increases the difficulty of the task. Common approaches include the detection of raindrop regions in the image, followed by performing a background restoration process conditioned on those regions. While various methods can be applied for the detection step, the most common architecture used for background restoration is the Generative Adversarial Network (GAN). Recent advances in the use of diffusion models have led to state-of-the-art image inpainting techniques. In this paper, we introduce a novel technique for raindrop removal from a single image using diffusion-based image inpainting.

Generalizable Pancreas Segmentation via a Dual Self-Supervised Learning Framework

Recently, numerous pancreas segmentation methods have achieved promising performance on local single-source datasets. However, these methods don't adequately account for generalizability issues, and hence typically show limited performance and low stability on test data from other sources. Considering the limited availability of distinct data sources, we seek to improve the generalization performance of a pancreas segmentation model trained with a single-source dataset, i.e., the single source generalization task. In particular, we propose a dual self-supervised learning model that incorporates both global and local anatomical contexts. Our model aims to fully exploit the anatomical features of the intra-pancreatic and extra-pancreatic regions, and hence enhance the characterization of the high-uncertainty regions for more robust generalization. Specifically, we first construct a global-feature contrastive self-supervised learning module that is guided by the pancreatic spatial structure. This module obtains complete and consistent pancreatic features through promoting intra-class cohesion, and also extracts more discriminative features for differentiating between pancreatic and non-pancreatic tissues through maximizing inter-class separation. It mitigates the influence of surrounding tissue on the segmentation outcomes in high-uncertainty regions. Subsequently, a local-image restoration self-supervised learning module is introduced to further enhance the characterization of the high uncertainty regions. In this module, informative anatomical contexts are actually learned to recover randomly corrupted appearance patterns in those regions.

UnfoldIR: Rethinking Deep Unfolding Network in Illumination Degradation Image Restoration

Deep unfolding networks (DUNs) are widely employed in illumination degradation image restoration (IDIR) to merge the interpretability of model-based approaches with the generalization of learning-based methods. However, the performance of DUN-based methods remains considerably inferior to that of state-of-the-art IDIR solvers. Our investigation indicates that this limitation does not stem from structural shortcomings of DUNs but rather from the limited exploration of the unfolding structure, particularly for (1) constructing task-specific restoration models, (2) integrating advanced network architectures, and (3) designing DUN-specific loss functions. To address these issues, we propose a novel DUN-based method, UnfoldIR, for IDIR tasks. UnfoldIR first introduces a new IDIR model with dedicated regularization terms for smoothing illumination and enhancing texture. We unfold the iterative optimized solution of this model into a multistage network, with each stage comprising a reflectance-assisted illumination correction (RAIC) module and an illumination-guided reflectance enhancement (IGRE) module. RAIC employs a visual state space (VSS) to extract non-local features, enforcing illumination smoothness, while IGRE introduces a frequency-aware VSS to globally align similar textures, enabling mildly degraded regions to guide the enhancement of details in more severely degraded areas. This suppresses noise while enhancing details. Furthermore, given the multistage structure, we propose an inter-stage information consistent loss to maintain network stability in the final stages. This loss contributes to structural preservation and sustains the model's performance even in unsupervised settings. Experiments verify our effectiveness across 5 IDIR tasks and 3 downstream problems.

Learning Cocoercive Conservative Denoisers via Helmholtz Decomposition for Poisson Inverse Problems

Plug-and-play (PnP) methods with deep denoisers have shown impressive results in imaging problems. They typically require strong convexity or smoothness of the fidelity term and a (residual) non-expansive denoiser for convergence. These assumptions, however, are violated in Poisson inverse problems, and non-expansiveness can hinder denoising performance. To address these challenges, we propose a cocoercive conservative (CoCo) denoiser, which may be (residual) expansive, leading to improved denoising. By leveraging the generalized Helmholtz decomposition, we introduce a novel training strategy that combines Hamiltonian regularization to promote conservativeness and spectral regularization to ensure cocoerciveness. We prove that CoCo denoiser is a proximal operator of a weakly convex function, enabling a restoration model with an implicit weakly convex prior. The global convergence of PnP methods to a stationary point of this restoration model is established. Extensive experimental results demonstrate that our approach outperforms closely related methods in both visual quality and quantitative metrics.

A Preliminary Study for GPT-4o on Image Restoration

OpenAI's GPT-4o model, integrating multi-modal inputs and outputs within an autoregressive architecture, has demonstrated unprecedented performance in image generation. In this work, we investigate its potential impact on the image restoration community. We present the first systematic evaluation of GPT-4o across diverse restoration tasks. Our experiments reveal that, although restoration outputs from GPT-4o are visually appealing, they often suffer from pixel-level structural fidelity when compared to ground-truth images. Common issues are variations in image proportions, shifts in object positions and quantities, and changes in viewpoint.To address it, taking image dehazing, derainning, and low-light enhancement as representative case studies, we show that GPT-4o's outputs can serve as powerful visual priors, substantially enhancing the performance of existing dehazing networks. It offers practical guidelines and a baseline framework to facilitate the integration of GPT-4o into future image restoration pipelines. We hope the study on GPT-4o image restoration will accelerate innovation in the broader field of image generation areas. To support further research, we will release GPT-4o-restored images from over 10 widely used image restoration datasets.

Image Restoration via Multi-domain Learning

Due to adverse atmospheric and imaging conditions, natural images suffer from various degradation phenomena. Consequently, image restoration has emerged as a key solution and garnered substantial attention. Although recent Transformer architectures have demonstrated impressive success across various restoration tasks, their considerable model complexity poses significant challenges for both training and real-time deployment. Furthermore, instead of investigating the commonalities among different degradations, most existing restoration methods focus on modifying Transformer under limited restoration priors. In this work, we first review various degradation phenomena under multi-domain perspective, identifying common priors. Then, we introduce a novel restoration framework, which integrates multi-domain learning into Transformer. Specifically, in Token Mixer, we propose a Spatial-Wavelet-Fourier multi-domain structure that facilitates local-region-global multi-receptive field modeling to replace vanilla self-attention. Additionally, in Feed-Forward Network, we incorporate multi-scale learning to fuse multi-domain features at different resolutions. Comprehensive experimental results across ten restoration tasks, such as dehazing, desnowing, motion deblurring, defocus deblurring, rain streak/raindrop removal, cloud removal, shadow removal, underwater enhancement and low-light enhancement, demonstrate that our proposed model outperforms state-of-the-art methods and achieves a favorable trade-off among restoration performance, parameter size, computational cost and inference latency. The code is available at: https://github.com/deng-ai-lab/SWFormer.