Guiding the Recommender: Information-Aware Auto-Bidding for Content Promotion

Modern content platforms offer paid promotion to mitigate cold start by allocating exposure via auctions. Our empirical analysis reveals a counterintuitive flaw in this paradigm: while promotion rescues low-to-medium quality content, it can harm high-quality content by forcing exposure to suboptimal audiences, polluting engagement signals and downgrading future recommendation. We recast content promotion as a dual-objective optimization that balances short-term value acquisition with long-term model improvement. To make this tractable at bid time in content promotion, we introduce a decomposable surrogate objective, gradient coverage, and establish its formal connection to Fisher Information and optimal experimental design. We design a two-stage auto-bidding algorithm based on Lagrange duality that dynamically paces budget through a shadow price and optimizes impression-level bids using per-impression marginal utilities. To address missing labels at bid time, we propose a confidence-gated gradient heuristic, paired with a zeroth-order variant for black-box models that reliably estimates learning signals in real time. We provide theoretical guarantees, proving monotone submodularity of the composite objective, sublinear regret in online auction, and budget feasibility. Extensive offline experiments on synthetic and real-world datasets validate the framework: it outperforms baselines, achieves superior final AUC/LogLoss, adheres closely to budget targets, and remains effective when gradients are approximated zeroth-order. These results show that strategic, information-aware promotion can improve long-term model performance and organic outcomes beyond naive impression-maximization strategies.

Lost in Tokenization: Context as the Key to Unlocking Biomolecular Understanding in Scientific LLMs

Scientific Large Language Models (Sci-LLMs) have emerged as a promising frontier for accelerating biological discovery. However, these models face a fundamental challenge when processing raw biomolecular sequences: the tokenization dilemma. Whether treating sequences as a specialized language, risking the loss of functional motif information, or as a separate modality, introducing formidable alignment challenges, current strategies fundamentally limit their reasoning capacity. We challenge this sequence-centric paradigm by positing that a more effective strategy is to provide Sci-LLMs with high-level structured context derived from established bioinformatics tools, thereby bypassing the need to interpret low-level noisy sequence data directly. Through a systematic comparison of leading Sci-LLMs on biological reasoning tasks, we tested three input modes: sequence-only, context-only, and a combination of both. Our findings are striking: the context-only approach consistently and substantially outperforms all other modes. Even more revealing, the inclusion of the raw sequence alongside its high-level context consistently degrades performance, indicating that raw sequences act as informational noise, even for models with specialized tokenization schemes. These results suggest that the primary strength of existing Sci-LLMs lies not in their nascent ability to interpret biomolecular syntax from scratch, but in their profound capacity for reasoning over structured, human-readable knowledge. Therefore, we argue for reframing Sci-LLMs not as sequence decoders, but as powerful reasoning engines over expert knowledge. This work lays the foundation for a new class of hybrid scientific AI agents, repositioning the developmental focus from direct sequence interpretation towards high-level knowledge synthesis. The code is available at github.com/opendatalab-raise-dev/CoKE.