A Differentiable Partially Observable Generalized Linear Model with Forward-Backward Message Passing

The partially observable generalized linear model (POGLM) is a powerful tool for understanding neural connectivity under the assumption of existing hidden neurons. With spike trains only recorded from visible neurons, existing works use variational inference to learn POGLM meanwhile presenting the difficulty of learning this latent variable model. There are two main issues: (1) the sampled Poisson hidden spike count hinders the use of the pathwise gradient estimator in VI; and (2) the existing design of the variational model is neither expressive nor time-efficient, which further affects the performance. For (1), we propose a new differentiable POGLM, which enables the pathwise gradient estimator, better than the score function gradient estimator used in existing works. For (2), we propose the forward-backward message-passing sampling scheme for the variational model. Comprehensive experiments show that our differentiable POGLMs with our forward-backward message passing produce a better performance on one synthetic and two real-world datasets. Furthermore, our new method yields more interpretable parameters, underscoring its significance in neuroscience.

Multi-Region Markovian Gaussian Process: An Efficient Method to Discover Directional Communications Across Multiple Brain Regions

Studying the complex interactions between different brain regions is crucial in neuroscience. Various statistical methods have explored the latent communication across multiple brain regions. Two main categories are the Gaussian Process (GP) and Linear Dynamical System (LDS), each with unique strengths. The GP-based approach effectively discovers latent variables such as frequency bands and communication directions. Conversely, the LDS-based approach is computationally efficient but lacks powerful expressiveness in latent representation. In this study, we merge both methodologies by creating an LDS mirroring a multi-output GP, termed Multi-Region Markovian Gaussian Process (MRM-GP). Our work is the first to establish a connection between an LDS and a multi-output GP that explicitly models frequencies and phase delays within the latent space of neural recordings. Consequently, the model achieves a linear inference cost over time points and provides an interpretable low-dimensional representation, revealing communication directions across brain regions and separating oscillatory communications into different frequency bands.

A Differentiable POGLM with Forward-Backward Message Passing

The partially observable generalized linear model (POGLM) is a powerful tool for understanding neural connectivity under the assumption of existing hidden neurons. With spike trains only recorded from visible neurons, existing works use variational inference to learn POGLM meanwhile presenting the difficulty of learning this latent variable model. There are two main issues: (1) the sampled Poisson hidden spike count hinders the use of the pathwise gradient estimator in VI; and (2) the existing design of the variational model is neither expressive nor time-efficient, which further affects the performance. For (1), we propose a new differentiable POGLM, which enables the pathwise gradient estimator, better than the score function gradient estimator used in existing works. For (2), we propose the forward-backward message-passing sampling scheme for the variational model. Comprehensive experiments show that our differentiable POGLMs with our forward-backward message passing produce a better performance on one synthetic and two real-world datasets. Furthermore, our new method yields more interpretable parameters, underscoring its significance in neuroscience.

Forward $χ^2$ Divergence Based Variational Importance Sampling

Maximizing the log-likelihood is a crucial aspect of learning latent variable models, and variational inference (VI) stands as the commonly adopted method. However, VI can encounter challenges in achieving a high log-likelihood when dealing with complicated posterior distributions. In response to this limitation, we introduce a novel variational importance sampling (VIS) approach that directly estimates and maximizes the log-likelihood. VIS leverages the optimal proposal distribution, achieved by minimizing the forward $\chi^2$ divergence, to enhance log-likelihood estimation. We apply VIS to various popular latent variable models, including mixture models, variational auto-encoders, and partially observable generalized linear models. Results demonstrate that our approach consistently outperforms state-of-the-art baselines, both in terms of log-likelihood and model parameter estimation.

Extraction and Recovery of Spatio-Temporal Structure in Latent Dynamics Alignment with Diffusion Model

In the field of behavior-related brain computation, it is necessary to meaningfully align raw neural population activities against the drastic shift between them. However, the alignment is non-trivial since most neural population activities are in a multivariate time-series manner. An instrumental framework within neuroscience research posits that trial-based neural population activities rely on low-dimensional latent dynamics. Focusing on such latent dynamics greatly facilitates the alignment procedure. Despite the considerable progress we have reached, existing methods usually ignore the intrinsic spatio-temporal structures within latent dynamics. Thus, those solutions lead to poor quality in dynamics structures and overall performance after alignment. To tackle this problem, we propose a method leveraging the expressiveness of diffusion model to relieve such issues. Specifically, the latent dynamics structures of the source domain are first extracted by the diffusion model. Then, such structures are well-recovered through a maximum likelihood alignment procedure on the target domain. We first demonstrate the effectiveness of our proposed method on a synthetic dataset. Then, when applied to neural recordings from primate motor cortex, under both cross-day and inter-subject settings, our method consistently manifests its capability of preserving the spatio-temporal structure of latent dynamics and outperforms existing approaches in alignment quality.

Extracting Attentive Social Temporal Excitation for Sequential Recommendation

In collaborative filtering, it is an important way to make full use of social information to improve the recommendation quality, which has been proved to be effective because user behavior will be affected by her friends. However, existing works leverage the social relationship to aggregate user features from friends' historical behavior sequences in a user-level indirect paradigm. A significant defect of the indirect paradigm is that it ignores the temporal relationships between behavior events across users. In this paper, we propose a novel time-aware sequential recommendation framework called Social Temporal Excitation Networks (STEN), which introduces temporal point processes to model the fine-grained impact of friends' behaviors on the user s dynamic interests in an event-level direct paradigm. Moreover, we propose to decompose the temporal effect in sequential recommendation into social mutual temporal effect and ego temporal effect. Specifically, we employ a social heterogeneous graph embedding layer to refine user representation via structural information. To enhance temporal information propagation, STEN directly extracts the fine-grained temporal mutual influence of friends' behaviors through the mutually exciting temporal network. Besides, the user s dynamic interests are captured through the self-exciting temporal network. Extensive experiments on three real-world datasets show that STEN outperforms state-of-the-art baseline methods. Moreover, STEN provides event-level recommendation explainability, which is also illustrated experimentally.

ICMT: Item Cluster-Wise Multi-Objective Training for Long-Tail Recommendation

Item recommendation based on historical user-item interactions is of vital importance for web-based services. However, the data used to train a recommender system (RS) suffers from severe popularity bias. Interactions of a small fraction of popular (head) items account for almost the whole training data. Normal training methods from such biased data tend to repetitively generate recommendations from the head items, which further exacerbates the data bias and affects the exploration of potentially interesting items from niche (tail) items. In this paper, we explore the central theme of long-tail recommendation. Through an empirical study, we find that head items are very likely to be recommended due to the fact that the gradients coming from head items dominate the overall gradient update process, which further affects the optimization of tail items. To this end, we propose a general framework namely Item Cluster-Wise Multi-Objective Training (ICMT) for long-tail recommendation. Firstly, the disentangled representation learning is utilized to identify the popularity impact behind user-item interactions. Then item clusters are adaptively formulated according to the disentangled popularity representation. After that, we consider the learning over the whole training data as a weighted aggregation of multiple item cluster-wise objectives, which can be resolved through a Pareto-Efficient solver for a harmonious overall gradient direction. Besides, a contractive loss focusing on model robustness is derived as a regularization term. We instantiate ICMT with three state-of-the-art recommendation models and conduct experiments on three real-world datasets. %Through alleviating the popularity bias, Experimental results demonstrate that the proposed ICMT significantly improves the overall recommendation performance, especially on tail items.

DemiNet: Dependency-Aware Multi-Interest Network with Self-Supervised Graph Learning for Click-Through Rate Prediction

In this paper, we propose a novel model named DemiNet (short for DEpendency-Aware Multi-Interest Network}) to address the above two issues. To be specific, we first consider various dependency types between item nodes and perform dependency-aware heterogeneous attention for denoising and obtaining accurate sequence item representations. Secondly, for multiple interests extraction, multi-head attention is conducted on top of the graph embedding. To filter out noisy inter-item correlations and enhance the robustness of extracted interests, self-supervised interest learning is introduced to the above two steps. Thirdly, to aggregate the multiple interests, interest experts corresponding to different interest routes give rating scores respectively, while a specialized network assigns the confidence of each score. Experimental results on three real-world datasets demonstrate that the proposed DemiNet significantly improves the overall recommendation performance over several state-of-the-art baselines. Further studies verify the efficacy and interpretability benefits brought from the fine-grained user interest modeling.

SAR Image Change Detection via Spatial Metric Learning with an Improved Mahalanobis Distance

The log-ratio (LR) operator has been widely employed to generate the difference image for synthetic aperture radar (SAR) image change detection. However, the difference image generated by this pixel-wise operator can be subject to SAR images speckle and unavoidable registration errors between bitemporal SAR images. In this letter, we proposed a spatial metric learning method to obtain a difference image more robust to the speckle by learning a metric from a set of constraint pairs. In the proposed method, spatial context is considered in constructing constraint pairs, each of which consists of patches in the same location of bitemporal SAR images. Then, a semi-definite positive metric matrix $\bf M$ can be obtained by the optimization with the max-margin criterion. Finally, we verify our proposed method on four challenging datasets of bitemporal SAR images. Experimental results demonstrate that the difference map obtained by our proposed method outperforms than other state-of-art methods.