Large language models surpass human experts in predicting neuroscience results

Scientific discoveries often hinge on synthesizing decades of research, a task that potentially outstrips human information processing capacities. Large language models (LLMs) offer a solution. LLMs trained on the vast scientific literature could potentially integrate noisy yet interrelated findings to forecast novel results better than human experts. To evaluate this possibility, we created BrainBench, a forward-looking benchmark for predicting neuroscience results. We find that LLMs surpass experts in predicting experimental outcomes. BrainGPT, an LLM we tuned on the neuroscience literature, performed better yet. Like human experts, when LLMs were confident in their predictions, they were more likely to be correct, which presages a future where humans and LLMs team together to make discoveries. Our approach is not neuroscience-specific and is transferable to other knowledge-intensive endeavors.

Understanding top-down attention using task-oriented ablation design

Top-down attention allows neural networks, both artificial and biological, to focus on the information most relevant for a given task. This is known to enhance performance in visual perception. But it remains unclear how attention brings about its perceptual boost, especially when it comes to naturalistic settings like recognising an object in an everyday scene. What aspects of a visual task does attention help to deal with? We aim to answer this with a computational experiment based on a general framework called task-oriented ablation design. First we define a broad range of visual tasks and identify six factors that underlie task variability. Then on each task we compare the performance of two neural networks, one with top-down attention and one without. These comparisons reveal the task-dependence of attention's perceptual boost, giving a clearer idea of the role attention plays. Whereas many existing cognitive accounts link attention to stimulus-level variables, such as visual clutter and object scale, we find greater explanatory power in system-level variables that capture the interaction between the model, the distribution of training data and the task format. This finding suggests a shift in how attention is studied could be fruitful. We make publicly available our code and results, along with statistics relevant to ImageNet-based experiments beyond this one. Our contribution serves to support the development of more human-like vision models and the design of more informative machine-learning experiments.

A Too-Good-to-be-True Prior to Reduce Shortcut Reliance

Despite their impressive performance in object recognition and other tasks under standard testing conditions, deep convolutional neural networks (DCNNs) often fail to generalize to out-of-distribution (o.o.d.) samples. One cause for this shortcoming is that modern architectures tend to rely on "shortcuts" - superficial features that correlate with categories without capturing deeper invariants that hold across contexts. Real-world concepts often possess a complex structure that can vary superficially across contexts, which can make the most intuitive and promising solutions in one context not generalize to others. One potential way to improve o.o.d. generalization is to assume simple solutions are unlikely to be valid across contexts and downweight them, which we refer to as the too-good-to-be-true prior. We implement this inductive bias in a two-stage approach that uses predictions from a low-capacity network (LCN) to inform the training of a high-capacity network (HCN). Since the shallow architecture of the LCN can only learn surface relationships, which includes shortcuts, we downweight training items for the HCN that the LCN can master, thereby encouraging the HCN to rely on deeper invariant features that should generalize broadly. Using a modified version of the CIFAR-10 dataset in which we introduced shortcuts, we found that the two-stage LCN-HCN approach reduced reliance on shortcuts and facilitated o.o.d. generalization.

The perceptual boost of visual attention is task-dependent in naturalistic settings

Attentional modulation of neural representations is known to enhance processing of task-relevant visual information. Is the resulting perceptual boost task-dependent in naturalistic settings? We aim to answer this with a large-scale computational experiment. First we design a series of visual tasks, each consisting of classifying images from a particular task set (group of image categories). The nature of a given task is determined by which categories are included in the task set. Then on each task we compare the accuracy of an attention-augmented neural network to that of an attention-free counterpart. We show that, all else being equal, the performance impact of attention is stronger with increasing task-set difficulty, weaker with increasing task-set size, and weaker with increasing perceptual similarity within a task set.

The Costs and Benefits of Goal-Directed Attention in Deep Convolutional Neural Networks

Attention in machine learning is largely bottom-up, whereas people also deploy top-down, goal-directed attention. Motivated by neuroscience research, we evaluated a plug-and-play, top-down attention layer that is easily added to existing deep convolutional neural networks (DCNNs). In object recognition tasks, increasing top-down attention has benefits (increasing hit rates) and costs (increasing false alarm rates). At a moderate level, attention improves sensitivity (i.e., increases $d^\prime$) at only a moderate increase in bias for tasks involving standard images, blended images, and natural adversarial images. These theoretical results suggest that top-down attention can effectively reconfigure general-purpose DCNNs to better suit the current task goal. We hope our results continue the fruitful dialog between neuroscience and machine learning.