The retinogeniculate pathway (RGVP) is responsible for carrying visual information from the retina to the lateral geniculate nucleus. Identification and visualization of the RGVP are important in studying the anatomy of the visual system and can inform treatment of related brain diseases. Diffusion MRI (dMRI) tractography is an advanced imaging method that uniquely enables in vivo mapping of the 3D trajectory of the RGVP. Currently, identification of the RGVP from tractography data relies on expert (manual) selection of tractography streamlines, which is time-consuming, has high clinical and expert labor costs, and affected by inter-observer variability. In this paper, we present what we believe is the first deep learning framework, namely DeepRGVP, to enable fast and accurate identification of the RGVP from dMRI tractography data. We design a novel microstructure-informed supervised contrastive learning method that leverages both streamline label and tissue microstructure information to determine positive and negative pairs. We propose a simple and successful streamline-level data augmentation method to address highly imbalanced training data, where the number of RGVP streamlines is much lower than that of non-RGVP streamlines. We perform comparisons with several state-of-the-art deep learning methods that were designed for tractography parcellation, and we show superior RGVP identification results using DeepRGVP.
A signed distance function (SDF) as the 3D shape description is one of the most effective approaches to represent 3D geometry for rendering and reconstruction. Our work is inspired by the state-of-the-art method DeepSDF that learns and analyzes the 3D shape as the iso-surface of its shell and this method has shown promising results especially in the 3D shape reconstruction and compression domain. In this paper, we consider the degeneration problem of reconstruction coming from the capacity decrease of the DeepSDF model, which approximates the SDF with a neural network and a single latent code. We propose Local Geometry Code Learning (LGCL), a model that improves the original DeepSDF results by learning from a local shape geometry of the full 3D shape. We add an extra graph neural network to split the single transmittable latent code into a set of local latent codes distributed on the 3D shape. Mentioned latent codes are used to approximate the SDF in their local regions, which will alleviate the complexity of the approximation compared to the original DeepSDF. Furthermore, we introduce a new geometric loss function to facilitate the training of these local latent codes. Note that other local shape adjusting methods use the 3D voxel representation, which in turn is a problem highly difficult to solve or even is insolvable. In contrast, our architecture is based on graph processing implicitly and performs the learning regression process directly in the latent code space, thus make the proposed architecture more flexible and also simple for realization. Our experiments on 3D shape reconstruction demonstrate that our LGCL method can keep more details with a significantly smaller size of the SDF decoder and outperforms considerably the original DeepSDF method under the most important quantitative metrics.
We propose a new approach of NoSQL database index selection. For different workloads, we select different indexes and their different parameters to optimize the database performance. The approach builds a deep reinforcement learning model to select an optimal index for a given fixed workload and adapts to a changing workload. Experimental results show that, Deep Reinforcement Learning Index Selection Approach (DRLISA) has improved performance to varying degrees according to traditional single index structures.