Consensus, dissensus and synergy between clinicians and specialist foundation models in radiology report generation

Radiology reports are an instrumental part of modern medicine, informing key clinical decisions such as diagnosis and treatment. The worldwide shortage of radiologists, however, restricts access to expert care and imposes heavy workloads, contributing to avoidable errors and delays in report delivery. While recent progress in automated report generation with vision-language models offer clear potential in ameliorating the situation, the path to real-world adoption has been stymied by the challenge of evaluating the clinical quality of AI-generated reports. In this study, we build a state-of-the-art report generation system for chest radiographs, \textit{Flamingo-CXR}, by fine-tuning a well-known vision-language foundation model on radiology data. To evaluate the quality of the AI-generated reports, a group of 16 certified radiologists provide detailed evaluations of AI-generated and human written reports for chest X-rays from an intensive care setting in the United States and an inpatient setting in India. At least one radiologist (out of two per case) preferred the AI report to the ground truth report in over 60$\%$ of cases for both datasets. Amongst the subset of AI-generated reports that contain errors, the most frequently cited reasons were related to the location and finding, whereas for human written reports, most mistakes were related to severity and finding. This disparity suggested potential complementarity between our AI system and human experts, prompting us to develop an assistive scenario in which \textit{Flamingo-CXR} generates a first-draft report, which is subsequently revised by a clinician. This is the first demonstration of clinician-AI collaboration for report writing, and the resultant reports are assessed to be equivalent or preferred by at least one radiologist to reports written by experts alone in 80$\%$ of in-patient cases and 60$\%$ of intensive care cases.

Improving alignment of dialogue agents via targeted human judgements

We present Sparrow, an information-seeking dialogue agent trained to be more helpful, correct, and harmless compared to prompted language model baselines. We use reinforcement learning from human feedback to train our models with two new additions to help human raters judge agent behaviour. First, to make our agent more helpful and harmless, we break down the requirements for good dialogue into natural language rules the agent should follow, and ask raters about each rule separately. We demonstrate that this breakdown enables us to collect more targeted human judgements of agent behaviour and allows for more efficient rule-conditional reward models. Second, our agent provides evidence from sources supporting factual claims when collecting preference judgements over model statements. For factual questions, evidence provided by Sparrow supports the sampled response 78% of the time. Sparrow is preferred more often than baselines while being more resilient to adversarial probing by humans, violating our rules only 8% of the time when probed. Finally, we conduct extensive analyses showing that though our model learns to follow our rules it can exhibit distributional biases.

Characteristics of Harmful Text: Towards Rigorous Benchmarking of Language Models

Large language models produce human-like text that drive a growing number of applications. However, recent literature and, increasingly, real world observations, have demonstrated that these models can generate language that is toxic, biased, untruthful or otherwise harmful. Though work to evaluate language model harms is under way, translating foresight about which harms may arise into rigorous benchmarks is not straightforward. To facilitate this translation, we outline six ways of characterizing harmful text which merit explicit consideration when designing new benchmarks. We then use these characteristics as a lens to identify trends and gaps in existing benchmarks. Finally, we apply them in a case study of the Perspective API, a toxicity classifier that is widely used in harm benchmarks. Our characteristics provide one piece of the bridge that translates between foresight and effective evaluation.

Scaling Language Models: Methods, Analysis & Insights from Training Gopher

Language modelling provides a step towards intelligent communication systems by harnessing large repositories of written human knowledge to better predict and understand the world. In this paper, we present an analysis of Transformer-based language model performance across a wide range of model scales -- from models with tens of millions of parameters up to a 280 billion parameter model called Gopher. These models are evaluated on 152 diverse tasks, achieving state-of-the-art performance across the majority. Gains from scale are largest in areas such as reading comprehension, fact-checking, and the identification of toxic language, but logical and mathematical reasoning see less benefit. We provide a holistic analysis of the training dataset and model's behaviour, covering the intersection of model scale with bias and toxicity. Finally we discuss the application of language models to AI safety and the mitigation of downstream harms.

Ethical and social risks of harm from Language Models

This paper aims to help structure the risk landscape associated with large-scale Language Models (LMs). In order to foster advances in responsible innovation, an in-depth understanding of the potential risks posed by these models is needed. A wide range of established and anticipated risks are analysed in detail, drawing on multidisciplinary expertise and literature from computer science, linguistics, and social sciences. We outline six specific risk areas: I. Discrimination, Exclusion and Toxicity, II. Information Hazards, III. Misinformation Harms, V. Malicious Uses, V. Human-Computer Interaction Harms, VI. Automation, Access, and Environmental Harms. The first area concerns the perpetuation of stereotypes, unfair discrimination, exclusionary norms, toxic language, and lower performance by social group for LMs. The second focuses on risks from private data leaks or LMs correctly inferring sensitive information. The third addresses risks arising from poor, false or misleading information including in sensitive domains, and knock-on risks such as the erosion of trust in shared information. The fourth considers risks from actors who try to use LMs to cause harm. The fifth focuses on risks specific to LLMs used to underpin conversational agents that interact with human users, including unsafe use, manipulation or deception. The sixth discusses the risk of environmental harm, job automation, and other challenges that may have a disparate effect on different social groups or communities. In total, we review 21 risks in-depth. We discuss the points of origin of different risks and point to potential mitigation approaches. Lastly, we discuss organisational responsibilities in implementing mitigations, and the role of collaboration and participation. We highlight directions for further research, particularly on expanding the toolkit for assessing and evaluating the outlined risks in LMs.

Challenges in Detoxifying Language Models

Large language models (LM) generate remarkably fluent text and can be efficiently adapted across NLP tasks. Measuring and guaranteeing the quality of generated text in terms of safety is imperative for deploying LMs in the real world; to this end, prior work often relies on automatic evaluation of LM toxicity. We critically discuss this approach, evaluate several toxicity mitigation strategies with respect to both automatic and human evaluation, and analyze consequences of toxicity mitigation in terms of model bias and LM quality. We demonstrate that while basic intervention strategies can effectively optimize previously established automatic metrics on the RealToxicityPrompts dataset, this comes at the cost of reduced LM coverage for both texts about, and dialects of, marginalized groups. Additionally, we find that human raters often disagree with high automatic toxicity scores after strong toxicity reduction interventions -- highlighting further the nuances involved in careful evaluation of LM toxicity.

Achieving Robustness in the Wild via Adversarial Mixing with Disentangled Representations

Recent research has made the surprising finding that state-of-the-art deep learning models sometimes fail to generalize to small variations of the input. Adversarial training has been shown to be an effective approach to overcome this problem. However, its application has been limited to enforcing invariance to analytically defined transformations like $\ell_p$-norm bounded perturbations. Such perturbations do not necessarily cover plausible real-world variations that preserve the semantics of the input (such as a change in lighting conditions). In this paper, we propose a novel approach to express and formalize robustness to these kinds of real-world transformations of the input. The two key ideas underlying our formulation are (1) leveraging disentangled representations of the input to define different factors of variations, and (2) generating new input images by adversarially composing the representations of different images. We use a StyleGAN model to demonstrate the efficacy of this framework. Specifically, we leverage the disentangled latent representations computed by a StyleGAN model to generate perturbations of an image that are similar to real-world variations (like adding make-up, or changing the skin-tone of a person) and train models to be invariant to these perturbations. Extensive experiments show that our method improves generalization and reduces the effect of spurious correlations.

Towards Robust Image Classification Using Sequential Attention Models

In this paper we propose to augment a modern neural-network architecture with an attention model inspired by human perception. Specifically, we adversarially train and analyze a neural model incorporating a human inspired, visual attention component that is guided by a recurrent top-down sequential process. Our experimental evaluation uncovers several notable findings about the robustness and behavior of this new model. First, introducing attention to the model significantly improves adversarial robustness resulting in state-of-the-art ImageNet accuracies under a wide range of random targeted attack strengths. Second, we show that by varying the number of attention steps (glances/fixations) for which the model is unrolled, we are able to make its defense capabilities stronger, even in light of stronger attacks --- resulting in a "computational race" between the attacker and the defender. Finally, we show that some of the adversarial examples generated by attacking our model are quite different from conventional adversarial examples --- they contain global, salient and spatially coherent structures coming from the target class that would be recognizable even to a human, and work by distracting the attention of the model away from the main object in the original image.

Reducing Sentiment Bias in Language Models via Counterfactual Evaluation

Recent improvements in large-scale language models have driven progress on automatic generation of syntactically and semantically consistent text for many real-world applications. Many of these advances leverage the availability of large corpora. While training on such corpora encourages the model to understand long-range dependencies in text, it can also result in the models internalizing the social biases present in the corpora. This paper aims to quantify and reduce biases exhibited by language models. Given a conditioning context (e.g. a writing prompt) and a language model, we analyze if (and how) the sentiment of the generated text is affected by changes in values of sensitive attributes (e.g. country names, occupations, genders, etc.) in the conditioning context, a.k.a. counterfactual evaluation. We quantify these biases by adapting individual and group fairness metrics from the fair machine learning literature. Extensive evaluation on two different corpora (news articles and Wikipedia) shows that state-of-the-art Transformer-based language models exhibit biases learned from data. We propose embedding-similarity and sentiment-similarity regularization methods that improve both individual and group fairness metrics without sacrificing perplexity and semantic similarity---a positive step toward development and deployment of fairer language models for real-world applications.

Learning Transferable Graph Exploration

This paper considers the problem of efficient exploration of unseen environments, a key challenge in AI. We propose a `learning to explore' framework where we learn a policy from a distribution of environments. At test time, presented with an unseen environment from the same distribution, the policy aims to generalize the exploration strategy to visit the maximum number of unique states in a limited number of steps. We particularly focus on environments with graph-structured state-spaces that are encountered in many important real-world applications like software testing and map building. We formulate this task as a reinforcement learning problem where the `exploration' agent is rewarded for transitioning to previously unseen environment states and employ a graph-structured memory to encode the agent's past trajectory. Experimental results demonstrate that our approach is extremely effective for exploration of spatial maps; and when applied on the challenging problems of coverage-guided software-testing of domain-specific programs and real-world mobile applications, it outperforms methods that have been hand-engineered by human experts.