TreeProbe : A Tibetan Medicine Benchmark for Cultural Bias in LLMs

Large language models are increasingly viewed as a potential means of mitigating global health inequities, yet their outputs often reflect dominant high-resource medical traditions and provide limited coverage of traditional medical knowledge systems. Tibetan medicine, one of the world's four major traditional medical systems, has an independent and highly structured theoretical framework. When models lack grounded understanding of Tibetan medicine, they may fall back on dominant epistemic systems and distort the native knowledge structure during reasoning. However, quantitative tools for evaluating cultural bias in Tibetan medicine remain largely absent. To address this gap, we introduce TreeProbe, the first cultural-bias benchmark organized around the native Tree of Medicine framework in Tibetan medicine. It contains 4,719 expert-adjudicated items covering 467 diseases and 10 subtasks along the three roots. Experiments on representative LLMs show that current models remain limited in native Tibetan medical contexts and exhibit systematic external ontology drift. Further analysis reveals that models diverge in whether they drift toward biomedical or TCM reasoning, shaped by pretraining data composition and surface resemblance between TCM and Tibetan medicine. TreeProbe provides a diagnostic benchmark for developing medical AI systems that are both linguistically inclusive and epistemically fair. Code and data are available in an anonymous repository at https://anonymous.4open.science/r/TreeProbe/.

Knowledge before Reasoning: EC-Reason-Bench, a Training-Free Diagnostic Benchmark for LLM Enzyme Classification

Enzyme function prediction is a hierarchical, knowledge-intensive form of protein function classification. Existing benchmarks expose an anomaly: general LLMs often get the coarse first level right, yet once asked for a complete EC number their accuracy at levels two through four drops to almost zero, while specialized models and tools stay usable. We propose EC-Reason-Bench, a training-free, diagnostic evaluation protocol built to answer two questions: why general LLMs score close to nothing on EC number prediction, and how much of that loss can be recovered without updating a single weight. We break enzyme classification ability into four orthogonal levers that can each be measured on their own: output structure, external knowledge, reasoning structure, and reasoning robustness. We test each lever with an inference-time method against a shared zero-shot baseline reproducing previously reported near-zero performance. Experiments with several strong reasoning LLMs yield four main findings. First, external knowledge is decisive and must precede reasoning: uniformly low closed-book performance rises sharply with open-book access, narrowing model gaps. Second, in closed-book settings, whether cascading and chain-of-thought help or hurt depends on a model's tendency to abstain. Third, once evidence is available the aggregate score of the best LLM setting is indistinguishable from simply voting the EC numbers of the nearest retrieved neighbors; that tie is an artifact of averaging, and it hides a large gain on adversarial evidence set against an equally large loss on multi-functional enzymes. Reasoning over evidence therefore acts as an arbiter of conflicting neighbors rather than as a source of knowledge, and no single-number leaderboard can see it. Fourth, accuracy obeys a law of homology availability.

Baichuan-M4: A Clinical-Grade Medical Agent System for Continuous Care

Baichuan-M4 is Baichuan Intelligence's clinical-grade medical large model, designed for continuous care rather than single-turn medical question answering. It is built as a coordinated medical agent system around three pillars: Baichuan-Harness, a unified runtime that keeps reinforcement-learning training and real-world deployment consistent while enforcing action constraints, tool use, long-term patient memory, and multi-agent coordination; a core reasoning model trained with a continuous-care reinforcement-learning framework that integrates span-level reward modeling (SPAR++), reasoning-path compression, curriculum learning, and stabilized policy optimization; and a clinical tool layer for patient-memory management, authoritative evidence-based retrieval, and multimodal medical perception across documents, X-rays, and dermatology. On a cross-dimensional medical evaluation suite, Baichuan-M4 attains leading results in static medical knowledge and safety, dynamic OSCE-style consultation, long-context clinical memory, evidence-based retrieval, medical document OCR, and multimodal image understanding, while lowering the hallucination rate to 3.3%.

SkillForge: Forging Domain-Specific, Self-Evolving Agent Skills in Cloud Technical Support

Deploying LLM-powered agents in enterprise scenarios such as cloud technical support demands high-quality, domain-specific skills. However, existing skill creators lack domain grounding, producing skills poorly aligned with real-world task requirements. Moreover, once deployed, there is no systematic mechanism to trace execution failures back to skill deficiencies and drive targeted refinements, leaving skill quality stagnant despite accumulating operational evidence. We introduce SkillForge, a self-evolving framework that closes an end-to-end creation-evaluation-refinement loop. To produce well-aligned initial skills, a Domain-Contextualized Skill Creator grounds skill synthesis in knowledge bases and historical support tickets. To enable continuous self-optimization, a three-stage pipeline -- Failure Analyzer, Skill Diagnostician, and Skill Optimizer -- automatically diagnoses execution failures in batch, pinpoints the underlying skill deficiencies, and rewrites the skill to eliminate them. This cycle runs iteratively, allowing skills to self-improve with every round of deployment feedback. Evaluated on five real-world cloud support scenarios spanning 1,883 tickets and 3,737 tasks, experiments show that: (1) the Domain-Contextualized Skill Creator produces substantially better initial skills than the generic skill creator, as measured by consistency with expert-authored reference responses from historical tickets; and (2) the self-evolution loop progressively improves skill quality from diverse starting points (including expert-authored, domain-created, and generic skills) across successive rounds, demonstrating that automated evolution can surpass manually curated expert knowledge.

When Modalities Remember: Continual Learning for Multimodal Knowledge Graphs

Real-world multimodal knowledge graphs (MMKGs) are dynamic, with new entities, relations, and multimodal knowledge emerging over time. Existing continual knowledge graph reasoning (CKGR) methods focus on structural triples and cannot fully exploit multimodal signals from new entities. Existing multimodal knowledge graph reasoning (MMKGR) methods, however, usually assume static graphs and suffer catastrophic forgetting as graphs evolve. To address this gap, we present a systematic study of continual multimodal knowledge graph reasoning (CMMKGR). We construct several continual multimodal knowledge graph benchmarks from existing MMKG datasets and propose MRCKG, a new CMMKGR model. Specifically, MRCKG employs a multimodal-structural collaborative curriculum to schedule progressive learning based on the structural connectivity of new triples to the historical graph and their multimodal compatibility. It also introduces a cross-modal knowledge preservation mechanism to mitigate forgetting through entity representation stability, relational semantic consistency, and modality anchoring. In addition, a multimodal contrastive replay scheme with a two-stage optimization strategy reinforces learned knowledge via multimodal importance sampling and representation alignment. Experiments on multiple datasets show that MRCKG preserves previously learned multimodal knowledge while substantially improving the learning of new knowledge.

Rethinking Regularization Methods for Knowledge Graph Completion

Knowledge graph completion (KGC) has attracted considerable attention in recent years because it is critical to improving the quality of knowledge graphs. Researchers have continuously explored various models. However, most previous efforts have neglected to take advantage of regularization from a deeper perspective and therefore have not been used to their full potential. This paper rethinks the application of regularization methods in KGC. Through extensive empirical studies on various KGC models, we find that carefully designed regularization not only alleviates overfitting and reduces variance but also enables these models to break through the upper bounds of their original performance. Furthermore, we introduce a novel sparse-regularization method that embeds the concept of rank-based selective sparsity into the KGC regularizer. The core idea is to selectively penalize those components with significant features in the embedding vector, thus effectively ignoring many components that contribute little and may only represent noise. Various comparative experiments on multiple datasets and multiple models show that the SPR regularization method is better than other regularization methods and can enable the KGC model to further break through the performance margin.

RetrieveAll: A Multilingual Named Entity Recognition Framework with Large Language Models

The rise of large language models has led to significant performance breakthroughs in named entity recognition (NER) for high-resource languages, yet there remains substantial room for improvement in low- and medium-resource languages. Existing multilingual NER methods face severe language interference during the multi-language adaptation process, manifested in feature conflicts between different languages and the competitive suppression of low-resource language features by high-resource languages. Although training a dedicated model for each language can mitigate such interference, it lacks scalability and incurs excessive computational costs in real-world applications. To address this issue, we propose RetrieveAll, a universal multilingual NER framework based on dynamic LoRA. The framework decouples task-specific features across languages and demonstrates efficient dynamic adaptability. Furthermore, we introduce a cross-granularity knowledge augmented method that fully exploits the intrinsic potential of the data without relying on external resources. By leveraging a hierarchical prompting mechanism to guide knowledge injection, this approach advances the paradigm from "prompt-guided inference" to "prompt-driven learning." Experimental results show that RetrieveAll outperforms existing baselines; on the PAN-X dataset, it achieves an average F1 improvement of 12.1 percent.

PROPHET: An Inferable Future Forecasting Benchmark with Causal Intervened Likelihood Estimation

Predicting future events stands as one of the ultimate aspirations of artificial intelligence. Recent advances in large language model (LLM)-based systems have shown remarkable potential in forecasting future events, thereby garnering significant interest in the research community. Currently, several benchmarks have been established to evaluate the forecasting capabilities by formalizing the event prediction as a retrieval-augmented generation (RAG) and reasoning task. In these benchmarks, each prediction question is answered with relevant retrieved news articles. However, because there is no consideration on whether the questions can be supported by valid or sufficient supporting rationales, some of the questions in these benchmarks may be inherently noninferable. To address this issue, we introduce a new benchmark, PROPHET, which comprises inferable forecasting questions paired with relevant news for retrieval. To ensure the inferability of the benchmark, we propose Causal Intervened Likelihood (CIL), a statistical measure that assesses inferability through causal inference. In constructing this benchmark, we first collected recent trend forecasting questions and then filtered the data using CIL, resulting in an inferable benchmark for event prediction. Through extensive experiments, we first demonstrate the validity of CIL and in-depth investigations into event prediction with the aid of CIL. Subsequently, we evaluate several representative prediction systems on PROPHET, drawing valuable insights for future directions.

A Coarse-to-fine Morphological Approach With Knowledge-based Rules and Self-adapting Correction for Lung Nodules Segmentation

The segmentation module which precisely outlines the nodules is a crucial step in a computer-aided diagnosis(CAD) system. The most challenging part of such a module is how to achieve high accuracy of the segmentation, especially for the juxtapleural, non-solid and small nodules. In this research, we present a coarse-to-fine methodology that greatly improves the thresholding method performance with a novel self-adapting correction algorithm and effectively removes noisy pixels with well-defined knowledge-based principles. Compared with recent strong morphological baselines, our algorithm, by combining dataset features, achieves state-of-the-art performance on both the public LIDC-IDRI dataset (DSC 0.699) and our private LC015 dataset (DSC 0.760) which closely approaches the SOTA deep learning-based models' performances. Furthermore, unlike most available morphological methods that can only segment the isolated and well-circumscribed nodules accurately, the precision of our method is totally independent of the nodule type or diameter, proving its applicability and generality.