FluoCLIP: Stain-Aware Focus Quality Assessment in Fluorescence Microscopy

Accurate focus quality assessment (FQA) in fluorescence microscopy remains challenging, as the stain-dependent optical properties of fluorescent dyes cause abrupt and heterogeneous focus shifts. However, existing datasets and models overlook this variability, treating focus quality as a stain-agnostic problem. In this work, we formulate the task of stain-aware FQA, emphasizing that focus behavior in fluorescence microscopy must be modeled as a function of staining characteristics. Through quantitative analysis of existing datasets (FocusPath, BBBC006) and our newly curated FluoMix, we demonstrate that focus-rank relationships vary substantially across stains, underscoring the need for stain-aware modeling in fluorescence microscopy. To support this new formulation, we propose FluoMix, the first dataset for stain-aware FQA that encompasses multiple tissues, fluorescent stains, and focus variations. Building on this dataset, we propose FluoCLIP, a two-stage vision-language framework that leverages CLIP's alignment capability to interpret focus quality in the context of biological staining. In the stain-grounding phase, FluoCLIP learns general stain representations by aligning textual stain tokens with visual features, while in the stain-guided ranking phase, it optimizes stain-specific rank prompts for ordinal focus prediction. Together, our formulation, dataset, and framework establish the first foundation for stain-aware FQA, and FluoCLIP achieves strong generalization across diverse fluorescence microscopy conditions.

VIRO: Robust and Efficient Neuro-Symbolic Reasoning with Verification for Referring Expression Comprehension

Referring Expression Comprehension (REC) aims to localize the image region corresponding to a natural-language query. Recent neuro-symbolic REC approaches leverage large language models (LLMs) and vision-language models (VLMs) to perform compositional reasoning, decomposing queries 4 structured programs and executing them step-by-step. While such approaches achieve interpretable reasoning and strong zero-shot generalization, they assume that intermediate reasoning steps are accurate. However, this assumption causes cascading errors: false detections and invalid relations propagate through the reasoning chain, yielding high-confidence false positives even when no target is present in the image. To address this limitation, we introduce Verification-Integrated Reasoning Operators (VIRO), a neuro-symbolic framework that embeds lightweight operator-level verifiers within reasoning steps. Each operator executes and validates its output, such as object existence or spatial relationship, thereby allowing the system to robustly handle no-target cases when verification conditions are not met. Our framework achieves state-of-the-art performance, reaching 61.1% balanced accuracy across target-present and no-target settings, and demonstrates generalization to real-world egocentric data. Furthermore, VIRO shows superior computational efficiency in terms of throughput, high reliability with a program failure rate of less than 0.3%, and scalability through decoupled program generation from execution.

WaterMod: Modular Token-Rank Partitioning for Probability-Balanced LLM Watermarking

Large language models now draft news, legal analyses, and software code with human-level fluency. At the same time, regulations such as the EU AI Act mandate that each synthetic passage carry an imperceptible, machine-verifiable mark for provenance. Conventional logit-based watermarks satisfy this requirement by selecting a pseudorandom green vocabulary at every decoding step and boosting its logits, yet the random split can exclude the highest-probability token and thus erode fluency. WaterMod mitigates this limitation through a probability-aware modular rule. The vocabulary is first sorted in descending model probability; the resulting ranks are then partitioned by the residue rank mod k, which distributes adjacent-and therefore semantically similar-tokens across different classes. A fixed bias of small magnitude is applied to one selected class. In the zero-bit setting (k=2), an entropy-adaptive gate selects either the even or the odd parity as the green list. Because the top two ranks fall into different parities, this choice embeds a detectable signal while guaranteeing that at least one high-probability token remains available for sampling. In the multi-bit regime (k>2), the current payload digit d selects the color class whose ranks satisfy rank mod k = d. Biasing the logits of that class embeds exactly one base-k digit per decoding step, thereby enabling fine-grained provenance tracing. The same modular arithmetic therefore supports both binary attribution and rich payloads. Experimental results demonstrate that WaterMod consistently attains strong watermark detection performance while maintaining generation quality in both zero-bit and multi-bit settings. This robustness holds across a range of tasks, including natural language generation, mathematical reasoning, and code synthesis. Our code and data are available at https://github.com/Shinwoo-Park/WaterMod.

Semantic Exploration with Adaptive Gating for Efficient Problem Solving with Language Models

Recent advancements in large language models (LLMs) have shown remarkable potential in various complex tasks requiring multi-step reasoning methods like tree search to explore diverse reasoning paths. However, existing methods often suffer from computational inefficiency and redundancy. First, they overlook the diversity of task difficulties, leading to unnecessarily extensive searches even for easy tasks. Second, they neglect the semantics of reasoning paths, resulting in redundant exploration of semantically identical paths. To address these limitations, we propose Semantic Exploration with Adaptive Gating (SEAG), a computationally efficient method. SEAG employs an adaptive gating mechanism that dynamically decides whether to conduct a tree search, based on the confidence level of answers from a preceding simple reasoning method. Furthermore, its tree-based exploration consolidates semantically identical reasoning steps, reducing redundant explorations while maintaining or even improving accuracy. Our extensive experiments demonstrate that SEAG significantly improves accuracy by 4.3% on average while requiring only 31% of computational costs compared to existing tree search-based methods on complex reasoning benchmarks including GSM8K and ARC with diverse language models such as Llama2, Llama3, and Mistral.

Retrieval-Augmented Generation with Estimation of Source Reliability

Retrieval-augmented generation (RAG) addresses key limitations of large language models (LLMs), such as hallucinations and outdated knowledge, by incorporating external databases. These databases typically consult multiple sources to encompass up-to-date and various information. However, standard RAG methods often overlook the heterogeneous source reliability in the multi-source database and retrieve documents solely based on relevance, making them prone to propagating misinformation. To address this, we propose Reliability-Aware RAG (RA-RAG) which estimates the reliability of multiple sources and incorporates this information into both retrieval and aggregation processes. Specifically, it iteratively estimates source reliability and true answers for a set of queries with no labelling. Then, it selectively retrieves relevant documents from a few of reliable sources and aggregates them using weighted majority voting, where the selective retrieval ensures scalability while not compromising the performance. We also introduce a benchmark designed to reflect real-world scenarios with heterogeneous source reliability and demonstrate the effectiveness of RA-RAG compared to a set of baselines.

Hybrid-TTA: Continual Test-time Adaptation via Dynamic Domain Shift Detection

Continual Test Time Adaptation (CTTA) has emerged as a critical approach for bridging the domain gap between the controlled training environments and the real-world scenarios, enhancing model adaptability and robustness. Existing CTTA methods, typically categorized into Full-Tuning (FT) and Efficient-Tuning (ET), struggle with effectively addressing domain shifts. To overcome these challenges, we propose Hybrid-TTA, a holistic approach that dynamically selects instance-wise tuning method for optimal adaptation. Our approach introduces the Dynamic Domain Shift Detection (DDSD) strategy, which identifies domain shifts by leveraging temporal correlations in input sequences and dynamically switches between FT and ET to adapt to varying domain shifts effectively. Additionally, the Masked Image Modeling based Adaptation (MIMA) framework is integrated to ensure domain-agnostic robustness with minimal computational overhead. Our Hybrid-TTA achieves a notable 1.6%p improvement in mIoU on the Cityscapes-to-ACDC benchmark dataset, surpassing previous state-of-the-art methods and offering a robust solution for real-world continual adaptation challenges.

Dynamic Guidance Adversarial Distillation with Enhanced Teacher Knowledge

In the realm of Adversarial Distillation (AD), strategic and precise knowledge transfer from an adversarially robust teacher model to a less robust student model is paramount. Our Dynamic Guidance Adversarial Distillation (DGAD) framework directly tackles the challenge of differential sample importance, with a keen focus on rectifying the teacher model's misclassifications. DGAD employs Misclassification-Aware Partitioning (MAP) to dynamically tailor the distillation focus, optimizing the learning process by steering towards the most reliable teacher predictions. Additionally, our Error-corrective Label Swapping (ELS) corrects misclassifications of the teacher on both clean and adversarially perturbed inputs, refining the quality of knowledge transfer. Further, Predictive Consistency Regularization (PCR) guarantees consistent performance of the student model across both clean and adversarial inputs, significantly enhancing its overall robustness. By integrating these methodologies, DGAD significantly improves upon the accuracy of clean data and fortifies the model's defenses against sophisticated adversarial threats. Our experimental validation on CIFAR10, CIFAR100, and Tiny ImageNet datasets, employing various model architectures, demonstrates the efficacy of DGAD, establishing it as a promising approach for enhancing both the robustness and accuracy of student models in adversarial settings.

Salience-Based Adaptive Masking: Revisiting Token Dynamics for Enhanced Pre-training

In this paper, we introduce Saliency-Based Adaptive Masking (SBAM), a novel and cost-effective approach that significantly enhances the pre-training performance of Masked Image Modeling (MIM) approaches by prioritizing token salience. Our method provides robustness against variations in masking ratios, effectively mitigating the performance instability issues common in existing methods. This relaxes the sensitivity of MIM-based pre-training to masking ratios, which in turn allows us to propose an adaptive strategy for `tailored' masking ratios for each data sample, which no existing method can provide. Toward this goal, we propose an Adaptive Masking Ratio (AMR) strategy that dynamically adjusts the proportion of masking for the unique content of each image based on token salience. We show that our method significantly improves over the state-of-the-art in mask-based pre-training on the ImageNet-1K dataset.

Emerging Property of Masked Token for Effective Pre-training

Driven by the success of Masked Language Modeling (MLM), the realm of self-supervised learning for computer vision has been invigorated by the central role of Masked Image Modeling (MIM) in driving recent breakthroughs. Notwithstanding the achievements of MIM across various downstream tasks, its overall efficiency is occasionally hampered by the lengthy duration of the pre-training phase. This paper presents a perspective that the optimization of masked tokens as a means of addressing the prevailing issue. Initially, we delve into an exploration of the inherent properties that a masked token ought to possess. Within the properties, we principally dedicated to articulating and emphasizing the `data singularity' attribute inherent in masked tokens. Through a comprehensive analysis of the heterogeneity between masked tokens and visible tokens within pre-trained models, we propose a novel approach termed masked token optimization (MTO), specifically designed to improve model efficiency through weight recalibration and the enhancement of the key property of masked tokens. The proposed method serves as an adaptable solution that seamlessly integrates into any MIM approach that leverages masked tokens. As a result, MTO achieves a considerable improvement in pre-training efficiency, resulting in an approximately 50% reduction in pre-training epochs required to attain converged performance of the recent approaches.

MedBN: Robust Test-Time Adaptation against Malicious Test Samples

Test-time adaptation (TTA) has emerged as a promising solution to address performance decay due to unforeseen distribution shifts between training and test data. While recent TTA methods excel in adapting to test data variations, such adaptability exposes a model to vulnerability against malicious examples, an aspect that has received limited attention. Previous studies have uncovered security vulnerabilities within TTA even when a small proportion of the test batch is maliciously manipulated. In response to the emerging threat, we propose median batch normalization (MedBN), leveraging the robustness of the median for statistics estimation within the batch normalization layer during test-time inference. Our method is algorithm-agnostic, thus allowing seamless integration with existing TTA frameworks. Our experimental results on benchmark datasets, including CIFAR10-C, CIFAR100-C and ImageNet-C, consistently demonstrate that MedBN outperforms existing approaches in maintaining robust performance across different attack scenarios, encompassing both instant and cumulative attacks. Through extensive experiments, we show that our approach sustains the performance even in the absence of attacks, achieving a practical balance between robustness and performance.