Prototypical-part interpretable methods, e.g., ProtoPNet, enhance interpretability by connecting classification predictions to class-specific training prototypes, thereby offering an intuitive insight into their decision-making. Current methods rely on a discriminative classifier trained with point-based learning techniques that provide specific values for prototypes. Such prototypes have relatively low representation power due to their sparsity and potential redundancy, with each prototype containing no variability measure. In this paper, we present a new generative learning of prototype distributions, named Mixture of Gaussian-distributed Prototypes (MGProto), which are represented by Gaussian mixture models (GMM). Such an approach enables the learning of more powerful prototype representations since each learned prototype will own a measure of variability, which naturally reduces the sparsity given the spread of the distribution around each prototype, and we also integrate a prototype diversity objective function into the GMM optimisation to reduce redundancy. Incidentally, the generative nature of MGProto offers a new and effective way for detecting out-of-distribution samples. To improve the compactness of MGProto, we further propose to prune Gaussian-distributed prototypes with a low prior. Experiments on CUB-200-2011, Stanford Cars, Stanford Dogs, and Oxford-IIIT Pets datasets show that MGProto achieves state-of-the-art classification and OoD detection performances with encouraging interpretability results.
The learning with noisy labels has been addressed with both discriminative and generative models. Although discriminative models have dominated the field due to their simpler modeling and more efficient computational training processes, generative models offer a more effective means of disentangling clean and noisy labels and improving the estimation of the label transition matrix. However, generative approaches maximize the joint likelihood of noisy labels and data using a complex formulation that only indirectly optimizes the model of interest associating data and clean labels. Additionally, these approaches rely on generative models that are challenging to train and tend to use uninformative clean label priors. In this paper, we propose a new generative noisy-label learning approach that addresses these three issues. First, we propose a new model optimisation that directly associates data and clean labels. Second, the generative model is implicitly estimated using a discriminative model, eliminating the inefficient training of a generative model. Third, we propose a new informative label prior inspired by partial label learning as supervision signal for noisy label learning. Extensive experiments on several noisy-label benchmarks demonstrate that our generative model provides state-of-the-art results while maintaining a similar computational complexity as discriminative models.
Audio-visual segmentation (AVS) is a complex task that involves accurately segmenting the corresponding sounding object based on audio-visual queries. Successful audio-visual learning requires two essential components: 1) an unbiased dataset with high-quality pixel-level multi-class labels, and 2) a model capable of effectively linking audio information with its corresponding visual object. However, these two requirements are only partially addressed by current methods, with training sets containing biased audio-visual data, and models that generalise poorly beyond this biased training set. In this work, we propose a new strategy to build cost-effective and relatively unbiased audio-visual semantic segmentation benchmarks. Our strategy, called Visual Post-production (VPO), explores the observation that it is not necessary to have explicit audio-visual pairs extracted from single video sources to build such benchmarks. We also refine the previously proposed AVSBench to transform it into the audio-visual semantic segmentation benchmark AVSBench-Single+. Furthermore, this paper introduces a new pixel-wise audio-visual contrastive learning method to enable a better generalisation of the model beyond the training set. We verify the validity of the VPO strategy by showing that state-of-the-art (SOTA) models trained with datasets built by matching audio and visual data from different sources or with datasets containing audio and visual data from the same video source produce almost the same accuracy. Then, using the proposed VPO benchmarks and AVSBench-Single+, we show that our method produces more accurate audio-visual semantic segmentation than SOTA models. Code and dataset will be available.
Methods to detect malignant lesions from screening mammograms are usually trained with fully annotated datasets, where images are labelled with the localisation and classification of cancerous lesions. However, real-world screening mammogram datasets commonly have a subset that is fully annotated and another subset that is weakly annotated with just the global classification (i.e., without lesion localisation). Given the large size of such datasets, researchers usually face a dilemma with the weakly annotated subset: to not use it or to fully annotate it. The first option will reduce detection accuracy because it does not use the whole dataset, and the second option is too expensive given that the annotation needs to be done by expert radiologists. In this paper, we propose a middle-ground solution for the dilemma, which is to formulate the training as a weakly- and semi-supervised learning problem that we refer to as malignant breast lesion detection with incomplete annotations. To address this problem, our new method comprises two stages, namely: 1) pre-training a multi-view mammogram classifier with weak supervision from the whole dataset, and 2) extending the trained classifier to become a multi-view detector that is trained with semi-supervised student-teacher learning, where the training set contains fully and weakly-annotated mammograms. We provide extensive detection results on two real-world screening mammogram datasets containing incomplete annotations, and show that our proposed approach achieves state-of-the-art results in the detection of malignant breast lesions with incomplete annotations.
Prototypical part network (ProtoPNet) methods have been designed to achieve interpretable classification by associating predictions with a set of training prototypes, which we refer to as trivial (i.e., easy-to-learn) prototypes because they are trained to lie far from the classification boundary in the feature space. Note that it is possible to make an analogy between ProtoPNet and support vector machine (SVM) given that the classification from both methods relies on computing similarity with a set of training points (i.e., trivial prototypes in ProtoPNet, and support vectors in SVM). However, while trivial prototypes are located far from the classification boundary, support vectors are located close to this boundary, and we argue that this discrepancy with the well-established SVM theory can result in ProtoPNet models with suboptimal classification accuracy. In this paper, we aim to improve the classification accuracy of ProtoPNet with a new method to learn support prototypes that lie near the classification boundary in the feature space, as suggested by the SVM theory. In addition, we target the improvement of classification interpretability with a new model, named ST-ProtoPNet, which exploits our support prototypes and the trivial prototypes to provide complementary interpretability information. Experimental results on CUB-200-2011, Stanford Cars, and Stanford Dogs datasets demonstrate that the proposed method achieves state-of-the-art classification accuracy and produces more visually meaningful and diverse prototypes.
Learning with noisy-labels has become an important research topic in computer vision where state-of-the-art (SOTA) methods explore: 1) prediction disagreement with co-teaching strategy that updates two models when they disagree on the prediction of training samples; and 2) sample selection to divide the training set into clean and noisy sets based on small training loss. However, the quick convergence of co-teaching models to select the same clean subsets combined with relatively fast overfitting of noisy labels may induce the wrong selection of noisy label samples as clean, leading to an inevitable confirmation bias that damages accuracy. In this paper, we introduce our noisy-label learning approach, called Asymmetric Co-teaching (AsyCo), which introduces novel prediction disagreement that produces more consistent divergent results of the co-teaching models, and a new sample selection approach that does not require small-loss assumption to enable a better robustness to confirmation bias than previous methods. More specifically, the new prediction disagreement is achieved with the use of different training strategies, where one model is trained with multi-class learning and the other with multi-label learning. Also, the new sample selection is based on multi-view consensus, which uses the label views from training labels and model predictions to divide the training set into clean and noisy for training the multi-class model and to re-label the training samples with multiple top-ranked labels for training the multi-label model. Extensive experiments on synthetic and real-world noisy-label datasets show that AsyCo improves over current SOTA methods.
State-of-the-art (SOTA) deep learning mammogram classifiers, trained with weakly-labelled images, often rely on global models that produce predictions with limited interpretability, which is a key barrier to their successful translation into clinical practice. On the other hand, prototype-based models improve interpretability by associating predictions with training image prototypes, but they are less accurate than global models and their prototypes tend to have poor diversity. We address these two issues with the proposal of BRAIxProtoPNet++, which adds interpretability to a global model by ensembling it with a prototype-based model. BRAIxProtoPNet++ distills the knowledge of the global model when training the prototype-based model with the goal of increasing the classification accuracy of the ensemble. Moreover, we propose an approach to increase prototype diversity by guaranteeing that all prototypes are associated with different training images. Experiments on weakly-labelled private and public datasets show that BRAIxProtoPNet++ has higher classification accuracy than SOTA global and prototype-based models. Using lesion localisation to assess model interpretability, we show BRAIxProtoPNet++ is more effective than other prototype-based models and post-hoc explanation of global models. Finally, we show that the diversity of the prototypes learned by BRAIxProtoPNet++ is superior to SOTA prototype-based approaches.
When analysing screening mammograms, radiologists can naturally process information across two ipsilateral views of each breast, namely the cranio-caudal (CC) and mediolateral-oblique (MLO) views. These multiple related images provide complementary diagnostic information and can improve the radiologist's classification accuracy. Unfortunately, most existing deep learning systems, trained with globally-labelled images, lack the ability to jointly analyse and integrate global and local information from these multiple views. By ignoring the potentially valuable information present in multiple images of a screening episode, one limits the potential accuracy of these systems. Here, we propose a new multi-view global-local analysis method that mimics the radiologist's reading procedure, based on a global consistency learning and local co-occurrence learning of ipsilateral views in mammograms. Extensive experiments show that our model outperforms competing methods, in terms of classification accuracy and generalisation, on a large-scale private dataset and two publicly available datasets, where models are exclusively trained and tested with global labels.
3D medical image segmentation methods have been successful, but their dependence on large amounts of voxel-level annotated data is a disadvantage that needs to be addressed given the high cost to obtain such annotation. Semi-supervised learning (SSL) solve this issue by training models with a large unlabelled and a small labelled dataset. The most successful SSL approaches are based on consistency learning that minimises the distance between model responses obtained from perturbed views of the unlabelled data. These perturbations usually keep the spatial input context between views fairly consistent, which may cause the model to learn segmentation patterns from the spatial input contexts instead of the segmented objects. In this paper, we introduce the Translation Consistent Co-training (TraCoCo) which is a consistency learning SSL method that perturbs the input data views by varying their spatial input context, allowing the model to learn segmentation patterns from visual objects. Furthermore, we propose the replacement of the commonly used mean squared error (MSE) semi-supervised loss by a new Cross-model confident Binary Cross entropy (CBC) loss, which improves training convergence and keeps the robustness to co-training pseudo-labelling mistakes. We also extend CutMix augmentation to 3D SSL to further improve generalisation. Our TraCoCo shows state-of-the-art results for the Left Atrium (LA) and Brain Tumor Segmentation (BRaTS19) datasets with different backbones. Our code is available at https://github.com/yyliu01/TraCoCo.