Abstract:Reinforcement Learning (RL) has demonstrated impressive capabilities in robotic control but remains challenging due to high sample complexity, safety concerns, and the sim-to-real gap. While offline RL eliminates the need for risky real-world exploration by learning from pre-collected data, it suffers from distributional shift, limiting policy generalization. Model-Based RL (MBRL) addresses this by leveraging predictive models for synthetic rollouts, yet existing approaches often lack robust uncertainty estimation, leading to compounding errors in offline settings. We introduce Offline Robotic World Model (RWM-O), a model-based approach that explicitly estimates epistemic uncertainty to improve policy learning without reliance on a physics simulator. By integrating these uncertainty estimates into policy optimization, our approach penalizes unreliable transitions, reducing overfitting to model errors and enhancing stability. Experimental results show that RWM-O improves generalization and safety, enabling policy learning purely from real-world data and advancing scalable, data-efficient RL for robotics.
Abstract:Acquiring physically plausible motor skills across diverse and unconventional morphologies-including humanoid robots, quadrupeds, and animals-is essential for advancing character simulation and robotics. Traditional methods, such as reinforcement learning (RL) are task- and body-specific, require extensive reward function engineering, and do not generalize well. Imitation learning offers an alternative but relies heavily on high-quality expert demonstrations, which are difficult to obtain for non-human morphologies. Video diffusion models, on the other hand, are capable of generating realistic videos of various morphologies, from humans to ants. Leveraging this capability, we propose a data-independent approach for skill acquisition that learns 3D motor skills from 2D-generated videos, with generalization capability to unconventional and non-human forms. Specifically, we guide the imitation learning process by leveraging vision transformers for video-based comparisons by calculating pair-wise distance between video embeddings. Along with video-encoding distance, we also use a computed similarity between segmented video frames as a guidance reward. We validate our method on locomotion tasks involving unique body configurations. In humanoid robot locomotion tasks, we demonstrate that 'No-data Imitation Learning' (NIL) outperforms baselines trained on 3D motion-capture data. Our results highlight the potential of leveraging generative video models for physically plausible skill learning with diverse morphologies, effectively replacing data collection with data generation for imitation learning.
Abstract:In reinforcement learning (RL), agents often struggle to perform well on tasks that differ from those encountered during training. This limitation presents a challenge to the broader deployment of RL in diverse and dynamic task settings. In this work, we introduce memory augmentation, a memory-based RL approach to improve task generalization. Our approach leverages task-structured augmentations to simulate plausible out-of-distribution scenarios and incorporates memory mechanisms to enable context-aware policy adaptation. Trained on a predefined set of tasks, our policy demonstrates the ability to generalize to unseen tasks through memory augmentation without requiring additional interactions with the environment. Through extensive simulation experiments and real-world hardware evaluations on legged locomotion tasks, we demonstrate that our approach achieves zero-shot generalization to unseen tasks while maintaining robust in-distribution performance and high sample efficiency.
Abstract:Combining the agility of legged locomotion with the capabilities of manipulation, loco-manipulation platforms have the potential to perform complex tasks in real-world applications. To this end, state-of-the-art quadrupeds with attached manipulators, such as the Boston Dynamics Spot, have emerged to provide a capable and robust platform. However, both the complexity of loco-manipulation control, as well as the black-box nature of commercial platforms pose challenges for developing accurate dynamics models and control policies. We address these challenges by developing a hand-crafted kinematic model for a quadruped-with-arm platform and, together with recent advances in Bayesian Neural Network (BNN)-based dynamics learning using physical priors, efficiently learn an accurate dynamics model from data. We then derive control policies for loco-manipulation via model-based reinforcement learning (RL). We demonstrate the effectiveness of this approach on hardware using the Boston Dynamics Spot with a manipulator, accurately performing dynamic end-effector trajectory tracking even in low data regimes.
Abstract:Learning robust and generalizable world models is crucial for enabling efficient and scalable robotic control in real-world environments. In this work, we introduce a novel framework for learning world models that accurately capture complex, partially observable, and stochastic dynamics. The proposed method employs a dual-autoregressive mechanism and self-supervised training to achieve reliable long-horizon predictions without relying on domain-specific inductive biases, ensuring adaptability across diverse robotic tasks. We further propose a policy optimization framework that leverages world models for efficient training in imagined environments and seamless deployment in real-world systems. Through extensive experiments, our approach consistently outperforms state-of-the-art methods, demonstrating superior autoregressive prediction accuracy, robustness to noise, and generalization across manipulation and locomotion tasks. Notably, policies trained with our method are successfully deployed on ANYmal D hardware in a zero-shot transfer, achieving robust performance with minimal sim-to-real performance loss. This work advances model-based reinforcement learning by addressing the challenges of long-horizon prediction, error accumulation, and sim-to-real transfer. By providing a scalable and robust framework, the introduced methods pave the way for adaptive and efficient robotic systems in real-world applications.
Abstract:Aerial robotics for transporting suspended payloads as the form of freely-floating manipulator are growing great interest in recent years. However, the prior information of the payload, such as the mass, is always hard to obtain accurately in practice. The force/torque caused by payload and residual dynamics will introduce unmodeled perturbations to the system, which negatively affects the closed-loop performance. Different from estimation-like methods, this paper proposes Neural Predictor, a learning-based approach to model force/torque caused by payload and residual dynamics as a dynamical system. It results a hybrid model including both the first-principles dynamics and the learned dynamics. This hybrid model is then integrated into a MPC framework to improve closed-loop performance. Effectiveness of proposed framework is verified extensively in both numerical simulations and real-world flight experiments. The results indicate that our approach can capture force/torque caused by payload and residual dynamics accurately, respond quickly to the changes of them and improve the closed-loop performance significantly. In particular, Neural Predictor outperforms a state-of-the-art learning-based estimator and has reduced the force and torque estimation errors by up to 66.15% and 33.33% while using less samples.
Abstract:In drug discovery, predicting the absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties of small-molecule drugs is critical for ensuring safety and efficacy. However, the process of accurately predicting these properties is often resource-intensive and requires extensive experimental data. To address this challenge, we propose SMILES-Mamba, a two-stage model that leverages both unlabeled and labeled data through a combination of self-supervised pretraining and fine-tuning strategies. The model first pre-trains on a large corpus of unlabeled SMILES strings to capture the underlying chemical structure and relationships, before being fine-tuned on smaller, labeled datasets specific to ADMET tasks. Our results demonstrate that SMILES-Mamba exhibits competitive performance across 22 ADMET datasets, achieving the highest score in 14 tasks, highlighting the potential of self-supervised learning in improving molecular property prediction. This approach not only enhances prediction accuracy but also reduces the dependence on large, labeled datasets, offering a promising direction for future research in drug discovery.
Abstract:In this work, we propose a novel learning-based method to jointly estimate the shape and subsurface scattering (SSS) parameters of translucent objects by utilizing polarization cues. Although polarization cues have been used in various applications, such as shape from polarization (SfP), BRDF estimation, and reflection removal, their application in SSS estimation has not yet been explored. Our observations indicate that the SSS affects not only the light intensity but also the polarization signal. Hence, the polarization signal can provide additional cues for SSS estimation. We also introduce the first large-scale synthetic dataset of polarized translucent objects for training our model. Our method outperforms several baselines from the SfP and inverse rendering realms on both synthetic and real data, as demonstrated by qualitative and quantitative results.
Abstract:Bringing a novel drug from the original idea to market typically requires more than ten years and billions of dollars. To alleviate the heavy burden, a natural idea is to reuse the approved drug to treat new diseases. The process is also known as drug repurposing or drug repositioning. Machine learning methods exhibited huge potential in automating drug repurposing. However, it still encounter some challenges, such as lack of labels and multimodal feature representation. To address these issues, we design DrugCLIP, a cutting-edge contrastive learning method, to learn drug and disease's interaction without negative labels. Additionally, we have curated a drug repurposing dataset based on real-world clinical trial records. Thorough empirical studies are conducted to validate the effectiveness of the proposed DrugCLIP method.
Abstract:Large language model systems face important security risks from maliciously crafted messages that aim to overwrite the system's original instructions or leak private data. To study this problem, we organized a capture-the-flag competition at IEEE SaTML 2024, where the flag is a secret string in the LLM system prompt. The competition was organized in two phases. In the first phase, teams developed defenses to prevent the model from leaking the secret. During the second phase, teams were challenged to extract the secrets hidden for defenses proposed by the other teams. This report summarizes the main insights from the competition. Notably, we found that all defenses were bypassed at least once, highlighting the difficulty of designing a successful defense and the necessity for additional research to protect LLM systems. To foster future research in this direction, we compiled a dataset with over 137k multi-turn attack chats and open-sourced the platform.