Climbing is a multifaceted sport that combines physical demands and emotional and cognitive challenges. Ascent styles differ in fall distance with lead climbing involving larger falls than top rope climbing, which may result in different perceived risk and fear. In this study, we investigated the psychophysiological relationship between perceived fear and muscle activity in climbers using a combination of statistical modeling and deep learning techniques. We conducted an experiment with 19 climbers, collecting electromyography (EMG), electrocardiography (ECG) and arm motion data during lead and top rope climbing. Perceived fear ratings were collected for the different phases of the climb. Using a linear mixed-effects model, we analyzed the relationships between perceived fear and physiological measures. To capture the non-linear dynamics of this relationship, we extended our analysis to deep learning models and integrated random effects for a personalized modeling approach. Our results showed that random effects improved model performance of the mean squared error (MSE), mean absolute error (MAE) and root mean squared error (RMSE). The results showed that muscle fatigue correlates significantly with increased fear during \textit{lead climbing}. This study highlights the potential of combining statistical and deep learning approaches for modeling the interplay between psychological and physiological states during climbing.
Long-term traffic modelling is fundamental to transport planning, but existing approaches often trade off interpretability, transferability, and predictive accuracy. Classical travel demand models provide behavioural structure but rely on strong assumptions and extensive calibration, whereas generic deep learning models capture complex patterns but often lack theoretical grounding and spatial transferability, limiting their usefulness for long-term planning applications. We propose DeepDemand, a theory-informed deep learning framework that embeds key components of travel demand theory to predict long-term highway traffic volumes using external socioeconomic features and road-network structure. The framework integrates a competitive two-source Dijkstra procedure for local origin-destination (OD) region extraction and OD pair screening with a differentiable architecture modelling OD interactions and travel-time deterrence. The model is evaluated using eight years (2017-2024) of observations on the UK strategic road network, covering 5088 highway segments. Under random cross-validation, DeepDemand achieves an R2 of 0.718 and an MAE of 7406 vehicles, outperforming linear, ridge, random forest, and gravity-style baselines. Performance remains strong under spatial cross-validation (R2 = 0.665), indicating good geographic transferability. Interpretability analysis reveals a stable nonlinear travel-time deterrence pattern, key socioeconomic drivers of demand, and polycentric OD interaction structures aligned with major employment centres and transport hubs. These results highlight the value of integrating transport theory with deep learning for interpretable highway traffic modelling and practical planning applications.
Efficient and adaptable deep learning models are an important area of deep learning research, driven by the need for highly efficient models on edge devices. Few-shot learning enables the use of deep learning models in low-data regimes, a capability that is highly sought after in real-world applications where collecting large annotated datasets is costly or impractical. This challenge is particularly relevant in edge scenarios, where connectivity may be limited, low-latency responses are required, or energy consumption constraints are critical. We propose and evaluate a pre-training method for the MobileViT backbone designed for edge computing. Specifically, we employ knowledge distillation, which transfers the generalization ability of a large-scale teacher model to a lightweight student model. This method achieves accuracy improvements of 14% and 6.7% for one-shot and five-shot classification, respectively, on the MiniImageNet benchmark, compared to the ResNet12 baseline, while reducing by 69% the number of parameters and by 88% the computational complexity of the model, in FLOPs. Furthermore, we deployed the proposed models on a Jetson Orin Nano platform and measured power consumption directly at the power supply, showing that the dynamic energy consumption is reduced by 37% with a latency of 2.6 ms. These results demonstrate that the proposed method is a promising and practical solution for deploying few-shot learning models on edge AI hardware.
Accurate drug response prediction is a critical bottleneck in computational biochemistry, limited by the challenge of modelling the interplay between molecular structure and cellular context. In cancer research, this is acute due to tumour heterogeneity and genomic variability, which hinder the identification of effective therapies. Conventional approaches often fail to capture non-linear relationships between chemical features and biological outcomes across diverse cell lines. To address this, we introduce DPD-Cancer, a deep learning method based on a Graph Attention Transformer (GAT) framework. It is designed for small molecule anti-cancer activity classification and the quantitative prediction of cell-line specific responses, specifically growth inhibition concentration (pGI50). Benchmarked against state-of-the-art methods (pdCSM-cancer, ACLPred, and MLASM), DPD-Cancer demonstrated superior performance, achieving an Area Under ROC Curve (AUC) of up to 0.87 on strictly partitioned NCI60 data and up to 0.98 on ACLPred/MLASM datasets. For pGI50 prediction across 10 cancer types and 73 cell lines, the model achieved Pearson's correlation coefficients of up to 0.72 on independent test sets. These findings confirm that attention-based mechanisms offer significant advantages in extracting meaningful molecular representations, establishing DPD-Cancer as a competitive tool for prioritising drug candidates. Furthermore, DPD-Cancer provides explainability by leveraging the attention mechanism to identify and visualise specific molecular substructures, offering actionable insights for lead optimisation. DPD-Cancer is freely available as a web server at: https://biosig.lab.uq.edu.au/dpd_cancer/.
Time series forecasting is critical across finance, healthcare, and cloud computing, yet progress is constrained by a fundamental bottleneck: the scarcity of large-scale, high-quality benchmarks. To address this gap, we introduce \textsc{QuitoBench}, a regime-balanced benchmark for time series forecasting with coverage across eight trend$\times$seasonality$\times$forecastability (TSF) regimes, designed to capture forecasting-relevant properties rather than application-defined domain labels. The benchmark is built upon \textsc{Quito}, a billion-scale time series corpus of application traffic from Alipay spanning nine business domains. Benchmarking 10 models from deep learning, foundation models, and statistical baselines across 232,200 evaluation instances, we report four key findings: (i) a context-length crossover where deep learning models lead at short context ($L=96$) but foundation models dominate at long context ($L \ge 576$); (ii) forecastability is the dominant difficulty driver, producing a $3.64 \times$ MAE gap across regimes; (iii) deep learning models match or surpass foundation models at $59 \times$ fewer parameters; and (iv) scaling the amount of training data provides substantially greater benefit than scaling model size for both model families. These findings are validated by strong cross-benchmark and cross-metric consistency. Our open-source release enables reproducible, regime-aware evaluation for time series forecasting research.
We study rank selection for low-rank tensor regression under random covariates design. Under a Gaussian random-design model and some mild conditions, we derive population expressions for the expected training-testing discrepancy (optimism) for both CP and Tucker decomposition. We further demonstrate that the optimism is minimized at the true tensor rank for both CP and Tucker regression. This yields a prediction-oriented rank-selection rule that aligns with cross-validation and extends naturally to tensor-model averaging. We also discuss conditions under which under- or over-ranked models may appear preferable, thereby clarifying the scope of the method. Finally, we showcase its practical utility on a real-world image regression task and extend its application to tensor-based compression of neural network, highlighting its potential for model selection in deep learning.
Missing data is a ubiquitous challenge in data analysis, often leading to biased and inaccurate results. Traditional imputation methods usually assume that the missingness mechanism is missing-at-random (MAR), where the missingness is independent of the missing values themselves. This assumption is frequently violated in real-world scenarios, prompted by recent advances in imputation methods using deep learning to address this challenge. However, these methods neglect the crucial issue of nonparametric identifiability in missing-not-at-random (MNAR) data, which can lead to biased and unreliable results. This paper seeks to bridge this gap by proposing a novel framework based on deep latent variable models for MNAR data. Building on the assumption of conditional no self-censoring given latent variables, we establish the identifiability of the data distribution. This crucial theoretical result guarantees the feasibility of our approach. To effectively estimate unknown parameters, we develop an efficient algorithm utilizing importance-weighted autoencoders. We demonstrate, both theoretically and empirically, that our estimation process accurately recovers the ground-truth joint distribution under specific regularity conditions. Extensive simulation studies and real-world data experiments showcase the advantages of our proposed method compared to various classical and state-of-the-art approaches to missing data imputation.
Real time sensor based applications in pervasive computing require edge deployable models to ensure low latency privacy and efficient interaction. A prime example is sensor based human activity recognition where models must balance accuracy with stringent resource constraints. Yet many deep learning approaches treat temporal sensor signals as black box sequences overlooking spectral temporal structure while demanding excessive computation. We present SPECTRA a deployment first co designed spectral temporal architecture that integrates short time Fourier transform STFT feature extraction depthwise separable convolutions and channel wise self attention to capture spectral temporal dependencies under real edge runtime and memory constraints. A compact bidirectional GRU with attention pooling summarizes within window dynamics at low cost reducing downstream model burden while preserving accuracy. Across five public HAR datasets SPECTRA matches or approaches larger CNN LSTM and Transformer baselines while substantially reducing parameters latency and energy. Deployments on a Google Pixel 9 smartphone and an STM32L4 microcontroller further demonstrate end to end deployable realtime private and efficient HAR.
Echo-planar imaging (EPI) remains the cornerstone of diffusion MRI, but it is prone to severe geometric distortions due to its rapid sampling scheme that renders the sequence highly sensitive to $B_{0}$ field inhomogeneities. While deep learning has helped improve MRI reconstruction, integrating robust geometric distortion correction into a self-supervised framework remains an unmet need. To address this, we present FINDER (Field-Integrated Network for Distortion-free EPI Reconstruction), a novel zero-shot, scan-specific framework that reformulates reconstruction as a joint optimization of the underlying image and the $B_{0}$ field map. Specifically, we employ a physics-guided unrolled network that integrates dual-domain denoisers and virtual coil extensions to enforce robust data consistency. This is coupled with an Implicit Neural Representation (INR) conditioned on spatial coordinates and latent image features to model the off-resonance field as a continuous, differentiable function. Employing an alternating minimization strategy, FINDER synergistically updates the reconstruction network and the field map, effectively disentangling susceptibility-induced geometric distortions from anatomical structures. Experimental results demonstrate that FINDER achieves superior geometric fidelity and image quality compared to state-of-the-art baselines, offering a robust solution for high-quality diffusion imaging.
In surgical training for medical students, proficiency development relies on expert-led skill assessment, which is costly, time-limited, difficult to scale, and its expertise remains confined to institutions with available specialists. Automated AI-based assessment offers a viable alternative, but progress is constrained by the lack of datasets containing realistic trainee errors and the multi-view variability needed to train robust computer vision approaches. To address this gap, we present Surgical-Hands (SHands), a large-scale multi-view video dataset for surgical hand-gesture and error recognition for medical training. \textsc{SHands} captures linear incision and suturing using five RGB cameras from complementary viewpoints, performed by 52 participants (20 experts and 32 trainees), each completing three standardized trials per procedure. The videos are annotated at the frame level with 15 gesture primitives and include a validated taxonomy of 8 trainee error types, enabling both gesture recognition and error detection. We further define standardized evaluation protocols for single-view, multi-view, and cross-view generalization, and benchmark state-of-the-art deep learning models on the dataset. SHands is publicly released to support the development of robust and scalable AI systems for surgical training grounded in clinically curated domain knowledge.