A Decade-Scale Benchmark Evaluating LLMs' Clinical Practice Guidelines Detection and Adherence in Multi-turn Conversations

Clinical practice guidelines (CPGs) play a pivotal role in ensuring evidence-based decision-making and improving patient outcomes. While Large Language Models (LLMs) are increasingly deployed in healthcare scenarios, it is unclear to which extend LLMs could identify and adhere to CPGs during conversations. To address this gap, we introduce CPGBench, an automated framework benchmarking the clinical guideline detection and adherence capabilities of LLMs in multi-turn conversations. We collect 3,418 CPG documents from 9 countries/regions and 2 international organizations published in the last decade spanning across 24 specialties. From these documents, we extract 32,155 clinical recommendations with corresponding publication institute, date, country, specialty, recommendation strength, evidence level, etc. One multi-turn conversation is generated for each recommendation accordingly to evaluate the detection and adherence capabilities of 8 leading LLMs. We find that the 71.1%-89.6% recommendations can be correctly detected, while only 3.6%-29.7% corresponding titles can be correctly referenced, revealing the gap between knowing the guideline contents and where they come from. The adherence rates range from 21.8% to 63.2% in different models, indicating a large gap between knowing the guidelines and being able to apply them. To confirm the validity of our automatic analysis, we further conduct a comprehensive human evaluation involving 56 clinicians from different specialties. To our knowledge, CPGBench is the first benchmark systematically revealing which clinical recommendations LLMs fail to detect or adhere to during conversations. Given that each clinical recommendation may affect a large population and that clinical applications are inherently safety critical, addressing these gaps is crucial for the safe and responsible deployment of LLMs in real world clinical practice.

Evaluating adaptive and generative AI-based feedback and recommendations in a knowledge-graph-integrated programming learning system

This paper introduces the design and development of a framework that integrates a large language model (LLM) with a retrieval-augmented generation (RAG) approach leveraging both a knowledge graph and user interaction history. The framework is incorporated into a previously developed adaptive learning support system to assess learners' code, generate formative feedback, and recommend exercises. Moerover, this study examines learner preferences across three instructional modes; adaptive, Generative AI (GenAI), and hybrid GenAI-adaptive. An experimental study was conducted to compare the learning performance and perception of the learners, and the effectiveness of these three modes using four key log features derived from 4956 code submissions across all experimental groups. The analysis results show that learners receiving feedback from GenAI modes had significantly more correct code and fewer code submissions missing essential programming logic than those receiving feedback from adaptive mode. In particular, the hybrid GenAI-adaptive mode achieved the highest number of correct submissions and the fewest incorrect or incomplete attempts, outperforming both the adaptive-only and GenAI-only modes. Questionnaire responses further indicated that GenAI-generated feedback was widely perceived as helpful, while all modes were rated positively for ease of use and usefulness. These results suggest that the hybrid GenAI-adaptive mode outperforms the other two modes across all measured log features.

Design Once, Deploy at Scale: Template-Driven ML Development for Large Model Ecosystems

Modern computational advertising platforms typically rely on recommendation systems to predict user responses, such as click-through rates, conversion rates, and other optimization events. To support a wide variety of product surfaces and advertiser goals, these platforms frequently maintain an extensive ecosystem of machine learning (ML) models. However, operating at this scale creates significant development and efficiency challenges. Substantial engineering effort is required to regularly refresh ML models and propagate new techniques, which results in long latencies when deploying ML innovations across the ecosystem. We present a large-scale empirical study comparing model performance, efficiency, and ML technique propagation between a standardized model-building approach and independent per-model optimization in recommendation systems. To facilitate this standardization, we propose the Standard Model Template (SMT) -- a framework that generates high-performance models adaptable to diverse data distributions and optimization events. By utilizing standardized, composable ML model components, SMT reduces technique propagation complexity from $O(n \cdot 2^k)$ to $O(n + k)$ where $n$ is the number of models and $k$ the number of techniques. Evaluating an extensive suite of models over four global development cycles within Meta's production ads ranking ecosystem, our results demonstrate: (1) a 0.63% average improvement in cross-entropy at neutral serving capacity, (2) a 92% reduction in per-model iteration engineering time, and (3) a $6.3\times$ increase in technique-model pair adoption throughput. These findings challenge the conventional wisdom that diverse optimization goals inherently require diversified ML model design.

Visual or Textual: Effects of Explanation Format and Personal Characteristics on the Perception of Explanations in an Educational Recommender System

Explanations are central to improving transparency, trust, and user satisfaction in recommender systems (RS), yet it remains unclear how different explanation formats (visual vs. textual) are suited to users with different personal characteristics (PCs). To this end, we report a within-subject user study (n=54) comparing visual and textual explanations and examine how explanation format and PCs jointly influence perceived control, transparency, trust, and satisfaction in an educational recommender system (ERS). Using robust mixed-effects models, we analyze the moderating effects of a wide range of PCs, including Big Five traits, need for cognition, decision making style, visualization familiarity, and technical expertise. Our results show that a well-designed visual, simple, interactive, selective, easy to understand visualization that clearly and intuitively communicates how user preferences are linked to recommendations, fosters perceived control, transparency, appropriate trust, and satisfaction in the ERS for most users, independent of their PCs. Moreover, we derive a set of guidelines to support the effective design of explanations in ERSs.

An Explainable Ensemble Learning Framework for Crop Classification with Optimized Feature Pyramids and Deep Networks

Agriculture is increasingly challenged by climate change, soil degradation, and resource depletion, and hence requires advanced data-driven crop classification and recommendation solutions. This work presents an explainable ensemble learning paradigm that fuses optimized feature pyramids, deep networks, self-attention mechanisms, and residual networks for bolstering crop suitability predictions based on soil characteristics (e.g., pH, nitrogen, potassium) and climatic conditions (e.g., temperature, rainfall). With a dataset comprising 3,867 instances and 29 features from the Ethiopian Agricultural Transformation Agency and NASA, the paradigm leverages preprocessing methods such as label encoding, outlier removal using IQR, normalization through StandardScaler, and SMOTE for balancing classes. A range of machine learning models such as Logistic Regression, K-Nearest Neighbors, Support Vector Machines, Decision Trees, Random Forest, Gradient Boosting, and a new Relative Error Support Vector Machine are compared, with hyperparameter tuning through Grid Search and cross-validation. The suggested "Final Ensemble" meta-ensemble design outperforms with 98.80% accuracy, precision, recall, and F1-score, compared to individual models such as K-Nearest Neighbors (95.56% accuracy). Explainable AI methods, such as SHAP and permutation importance, offer actionable insights, highlighting critical features such as soil pH, nitrogen, and zinc. The paradigm addresses the gap between intricate ML models and actionable agricultural decision-making, fostering sustainability and trust in AI-powered recommendations

DIET: Learning to Distill Dataset Continually for Recommender Systems

Modern deep recommender models are trained under a continual learning paradigm, relying on massive and continuously growing streaming behavioral logs. In large-scale platforms, retraining models on full historical data for architecture comparison or iteration is prohibitively expensive, severely slowing down model development. This challenge calls for data-efficient approaches that can faithfully approximate full-data training behavior without repeatedly processing the entire evolving data stream. We formulate this problem as \emph{streaming dataset distillation for recommender systems} and propose \textbf{DIET}, a unified framework that maintains a compact distilled dataset which evolves alongside streaming data while preserving training-critical signals. Unlike existing dataset distillation methods that construct a static distilled set, DIET models distilled data as an evolving training memory and updates it in a stage-wise manner to remain aligned with long-term training dynamics. DIET enables effective continual distillation through principled initialization from influential samples and selective updates guided by influence-aware memory addressing within a bi-level optimization framework. Experiments on large-scale recommendation benchmarks demonstrate that DIET compresses training data to as little as \textbf{1-2\%} of the original size while preserving performance trends consistent with full-data training, reducing model iteration cost by up to \textbf{60$\times$}. Moreover, the distilled datasets produced by DIET generalize well across different model architectures, highlighting streaming dataset distillation as a scalable and reusable data foundation for recommender system development.

Doctorina MedBench: End-to-End Evaluation of Agent-Based Medical AI

We present Doctorina MedBench, a comprehensive evaluation framework for agent-based medical AI based on the simulation of realistic physician-patient interactions. Unlike traditional medical benchmarks that rely on solving standardized test questions, the proposed approach models a multi-step clinical dialogue in which either a physician or an AI system must collect medical history, analyze attached materials (including laboratory reports, images, and medical documents), formulate differential diagnoses, and provide personalized recommendations. System performance is evaluated using the D.O.T.S. metric, which consists of four components: Diagnosis, Observations/Investigations, Treatment, and Step Count, enabling assessment of both clinical correctness and dialogue efficiency. The system also incorporates a multi-level testing and quality monitoring architecture designed to detect model degradation during both development and deployment. The framework supports safety-oriented trap cases, category-based random sampling of clinical scenarios, and full regression testing. The dataset currently contains more than 1,000 clinical cases covering over 750 diagnoses. The universality of the evaluation metrics allows the framework to be used not only to assess medical AI systems, but also to evaluate physicians and support the development of clinical reasoning skills. Our results suggest that simulation of clinical dialogue may provide a more realistic assessment of clinical competence compared to traditional examination-style benchmarks.

MCLMR: A Model-Agnostic Causal Learning Framework for Multi-Behavior Recommendation

Multi-Behavior Recommendation (MBR) leverages multiple user interaction types (e.g., views, clicks, purchases) to enrich preference modeling and alleviate data sparsity issues in traditional single-behavior approaches. However, existing MBR methods face fundamental challenges: they lack principled frameworks to model complex confounding effects from user behavioral habits and item multi-behavior distributions, struggle with effective aggregation of heterogeneous auxiliary behaviors, and fail to align behavioral representations across semantic gaps while accounting for bias distortions. To address these limitations, we propose MCLMR, a novel model-agnostic causal learning framework that can be seamlessly integrated into various MBR architectures. MCLMR first constructs a causal graph to model confounding effects and performs interventions for unbiased preference estimation. Under this causal framework, it employs an Adaptive Aggregation module based on Mixture-of-Experts to dynamically fuse auxiliary behavior information and a Bias-aware Contrastive Learning module to align cross-behavior representations in a bias-aware manner. Extensive experiments on three real-world datasets demonstrate that MCLMR achieves significant performance improvements across various baseline models, validating its effectiveness and generality. All data and code will be made publicly available. For anonymous review, our code is available at the following the link: https://github.com/gitrxh/MCLMR.

Hyena Operator for Fast Sequential Recommendation

Sequential recommendation models, particularly those based on attention, achieve strong accuracy but incur quadratic complexity, making long user histories prohibitively expensive. Sub-quadratic operators such as Hyena provide efficient alternatives in language modeling, but their potential in recommendation remains underexplored. We argue that Hyena faces challenges in recommendation due to limited representation capacity on sparse, long user sequences. To address these challenges, we propose HyenaRec, a novel sequential recommender that integrates polynomial-based kernel parameterization with gated convolutions. Specifically, we design convolutional kernels using Legendre orthogonal polynomials, which provides a smooth and compact basis for modeling long-term temporal dependencies. A complementary gating mechanism captures fine-grained short-term behavioral bursts, yielding a hybrid architecture that balances global temporal evolution with localized user interests under sparse feedback. This construction enhances expressiveness while scaling linearly with sequence length. Extensive experiments on multiple real-world datasets demonstrate that HyenaRec consistently outperforms Attention-, Recurrent-, and other baselines in ranking accuracy. Moreover, it trains significantly faster (up to 6x speedup), with particularly pronounced advantages on long-sequence scenarios where efficiency is maintained without sacrificing accuracy. These results highlight polynomial-based kernel parameterization as a principled and scalable alternative to attention for sequential recommendation.

Shaping the Future of Mathematics in the Age of AI

Artificial intelligence is transforming mathematics at a speed and scale that demand active engagement from the mathematical community. We examine five areas where this transformation is particularly pressing: values, practice, teaching, technology, and ethics. We offer recommendations on safeguarding our intellectual autonomy, rethinking our practice, broadening curricula, building academically oriented infrastructure, and developing shared ethical principles - with the aim of ensuring that the future of mathematics is shaped by the community itself.